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421
Evaluation of microRNAs as liquid biopsy markers in adrenocortical tumors
Published 2025-01-01“…IntroductionAdrenal tumors (ATs) encompass a wide differential diagnosis, necessitating a multi-step process for accurate identification. Liquid biopsy emerges as a promising non-invasive technique for distinguishing between malignant and benign, as well as hyperfunctioning and non-functioning cases. …”
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422
LABELING EXTRACELLULAR VESICLES FOR HIGHLY SENSITIVE FLOW CYTOMETRY ANALYSES
Published 2025-08-01“…Sorted EVs preparations resulted particularly suitable for proteomic analyses, which we applied to study their protein cargo, as well as for in vitro and in vivo functional assays. Therefore, LCD staining of EVs may open new routes for the EV clinical translation. …”
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423
Genome-wide analysis clarifies the population genetic structure of wild gilthead sea bream (Sparus aurata).
Published 2021-01-01“…Seascape analysis suggested that this differentiation was mainly due to difference in salinity, this being also supported by preliminary genomic functional analysis. These results are of fundamental importance for the development of proper management of this species in the wild and are a first step toward the study of the potential genetic impact of the sea bream aquaculture industry.…”
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424
Hematopoietic stem cells contribute to lymphatic endothelium.
Published 2008-01-01“…Donor-derived LECs were not detected in mice transplanted with common myeloid progenitors and granulocyte/macrophage progenitors, suggesting that myeloid lineage commitment is not a requisite step in HSC contribution to lymphatic endothelium. …”
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425
Computer‐aided biochemical programming of synthetic microreactors as diagnostic devices
Published 2018-04-01“…However, assembling biochemical parts into functional information processing systems has remained challenging due to extensive multidimensional parameter spaces that must be sampled comprehensively in order to identify robust, specification compliant molecular implementations. …”
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426
Pharyngeal mechanosensory neurons control food swallow in Drosophila melanogaster
Published 2024-12-01“…Inhibition of them causes difficulty in food emptying in the cibarium, while their activation leads to difficulty in cibarium filling. Synaptic and functional connections are detected between the pharyngeal mechanosensory neurons and the motor circuit that controls swallow. …”
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427
Translation and validation of the Saint Louis University Mental Status (SLUMS) Exam for older adults in Thailand: The SLUMS-Thai
Published 2025-08-01“…Background: The Saint Louis University Mental Status (SLUMS) Exam is a commonly used tool for screening cognitive function, particularly for detecting mild cognitive impairment (MCI) and early dementia. …”
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428
Integrating plot-based methods for monitoring biodiversity in island habitats under the scope of BIODIVERSA + project BioMonI: Tree monitoring in Terceira, Tenerife and Réunion Isl...
Published 2025-06-01“…Such data underpin the detection of subtle shifts in community composition, functional diversity and species distributions, which are critical for assessing the effectiveness of conservation actions and predicting future ecological scenarios.In summary, plot-based data are indispensable for targeted and effective biodiversity monitoring on islands. …”
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429
Large-scale discovery of promoter motifs in Drosophila melanogaster.
Published 2007-01-01“…A key step in understanding gene regulation is to identify the repertoire of transcription factor binding motifs (TFBMs) that form the building blocks of promoters and other regulatory elements. …”
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430
p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
Published 2004-08-01“…Skin tumors were induced in wild-type, p19(Arf)-deficient, and p53-deficient mice using the DMBA/TPA two-step protocol. Activating mutations in Hras were detected in all papillomas and carcinomas examined, regardless of genotype. …”
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431
Feasibility of estimating the percentage of desert pavement using Tasseled Cap Transformation indices extracted from Landsat 8 images
Published 2024-08-01“…Creating a detailed surface map is the initial step towards quantitative analysis of this role. …”
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432
Colorectal cancer vaccines: in silico identification of tumor-specific antigens associated with frequent HLA-I alleles in the costa rican Central Valley population
Published 2022-11-01“…We used public data of human exome (DNA regions that produce functional products, including proteins). A variant calling analysis was implemented to detect tumorspecific SNVs, in comparison to healthy tissue. …”
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433
Hyccin, the molecule mutated in the leukodystrophy hypomyelination and congenital cataract (HCC), is a neuronal protein.
Published 2012-01-01“…Since the identification of the cell types expressing a protein of unknown function can contribute to define the physiological context in which the molecule is explicating its function, we analyzed the pattern of Hyccin expression in the central and peripheral nervous system (CNS and PNS). …”
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434
Membrane Permeability Monitoring to Antipsychotic Olanzapine Using Platinum Black-Modified Electrodes
Published 2025-04-01“…The blood–brain barrier (BBB) is key to the regular functioning of the central nervous system. The dysfunction of the BBB has been described in various neurological disorders, including schizophrenia. …”
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435
Methodology for Verification of Geometrically Complex Components Through Reverse Engineering
Published 2025-04-01“…Verification of geometrically complex components is a crucial step in ensuring the quality and functionality of industrial products. …”
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436
The N-terminus of murine leukaemia virus p12 protein is required for mature core stability.
Published 2014-10-01“…The murine leukaemia virus (MLV) gag gene encodes a small protein called p12 that is essential for the early steps of viral replication. The N- and C-terminal regions of p12 are sequentially acting domains, both required for p12 function. …”
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437
New Possibilities for Evaluating Markers of Alzheimer's Disease in Blood Serum
Published 2025-06-01“…Results. Graphene functionalized with sulfo groups from pyranine exhibits sufficient ability to immobilize antibodies. …”
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438
The effect of body-conforming passive wearable device with knee flexion taping on dynamic knee stability
Published 2025-01-01“…There is increasing interest in adding functionality, such as knee stability, to these compact devices, which are more convenient for daily wear than separate devices like braces or exoskeletons. …”
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439
A RARE DISEASE ASSOCIATED WITH IG4, CHARACTERIZED BY SYSTEMIC AMYLOIDOSIS AND LYMPHOPLASMACYTIC CELL DOMINANCE: A CASE PRESENTATION
Published 2024-12-01“…With therapy, patients often experience a reduction in symptoms, a decrease in the size of masses in affected organs, improvement in organ function, and a general decline in serum IgG4 levels over several weeks. …”
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440
Automatic Filtering of Sugarcane Yield Data
Published 2024-12-01“…Sugarcane mechanized harvesting generates large volumes of data that are used to monitor harvesters’ functionalities. The dynamic interaction of the machine-onboard instrumentation–crop system introduces discrepant and noisy values into the data, requiring outlier detectors to support this complex and empirical decision. …”
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