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Integrated Single-Step Terahertz Metasensing for Simultaneous Detection Based on Exosomal Membrane Proteins Enables Pathological Typing of Gastric Cancer
Published 2025-01-01“…Characterized by dual-sided independent sensing capabilities with enhanced sensitivity (169 and 325 GHz per refractive index unit, respectively), the metasensor functionalized with antibodies simultaneously reflects the content of 2 membrane proteins in the terahertz spectral response. …”
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The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster.
Published 2012-01-01“…Drosophila has a single CPEB gene, orb and orb2, from each subfamily. orb expression is only detected at high levels in the germline and has critical functions in oogenesis but not spermatogenesis. …”
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Automated identification of soil functional components based on NanoSIMS data
Published 2024-12-01“…The tool is provided as an open-source software toolbox (NanoT). In addition, a two-step unsupervised segmentation method was developed to identify soil functional components based on NanoSIMS analyses. …”
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Femtosecond Laser‐Regulated Microstructures for on‐Demand Functionalization of Magnetic Milli‐Robots
Published 2025-08-01“…As a proof of concept, the functionalized milli‐robot is demonstrated for on‐demand gastric cancer detection, highlighting its potential for real‐time, non‐invasive diagnostics. …”
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Evaluating the effects of coffee consumption on the structure and function of the heart from multiple perspectives
Published 2025-04-01“…ObjectiveTo assess the causal relationship between coffee consumption and cardiac structure and function in elderly European populations using multiple genetic methodologies.MethodsLeveraging genome-wide association study (GWAS) data from elderly European populations, we conducted linkage disequilibrium score regression (LDSC), two-step Mendelian randomization (MR), and colocalization analyses to investigate genetic associations, causal relationships, and mediating effects among these factors. …”
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Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments
Published 2025-03-01“…To mitigate classification imbalances, we employed Tversky loss functions in the ultrasound image classification process.ResultsIn semantic image segmentation, DeepLabV3+ achieved an impressive Intersection over Union (IoU) of 94.37%, while utilizing only 12.4 MB of parameters, including weights and biases. …”
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Association of Fatigue Severity with Balance, Strength, and Functional Independence in Community Dwelling Poststroke Hemiparesis
Published 2024-12-01“…Conclusion: Fatigue can be a contributory factor for loss balance, strength, and functional independence. Early detection and treatment of fatigue can, therefore, help to reduce imbalance, functional dependence, and the risk of falling.…”
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The PINK1-Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells.
Published 2021-01-01“…Our findings suggest that the PINK1 -Parkin mitophagy signalling pathway is not functional in PBMCs. Therefore, PBMCs are not a suitable biosample for analysis of mitophagy function in Parkinson disease patients.…”
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A rapid and robust protocol for generating loss-of-function alleles in pluripotent stem cells
Published 2025-09-01“…Summary: The generation of loss-of-function alleles in human pluripotent stem cells (hPSCs) is used to interrogate gene function and validate reagents; however, identifying clones harboring true loss-of-function alleles remains inefficient. …”
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Damage identification of structures using experimental modal analysis and continuous wavelet transform
Published 2017-07-01“…EMA, which is also known as frequency response function (FRF) testing, has been widely preferred for the modal parameter estimation of structures. …”
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Functionalized novel carbon dots from bell pepper seeds for sustainable green Edoxaban quantification
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Autochthonous lactic acid bacteria from Kaddid as functional starter culture to improve quality and safety
Published 2025-04-01“…As a quality criterion, no exopolysaccharides and biogenic amines production were detected in the evaluated strains. Based on these results, Lpb. paraplantarum K18 strain, with inhibitory and antifungal activities, phenotypical susceptibility to the assayed antimicrobial compounds and low risk as spoilers, could be used as functional starter cultures for safe fermented meat production.…”
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Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript.
Published 2010-05-01“…Thus phenotypically "undifferentiated" cells may consist of a heterogeneous population of functionally distinct cell types. Here we use a transgenic allele designed to detect low level transcription in the primitive endoderm lineage as a tool to identify an immediate early endoderm-like ES cell state. …”
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Measuring nanoscale friction at graphene step edges
Published 2019-12-01“…The resistive component is attributed to chemical interactions between the functional groups at the tip and step-edge surfaces, and the assistive component is due to the topographic effect, same as the case of buried step edge. …”
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Complex Assessment of the Functional State of the Urinary System in Preclinical Studies. Part 2. Markers of Nephrotoxicity (Review)
Published 2024-09-01“…The determination of nephrotoxicity markers is a useful and necessary step in the detection of renal injury in animal experiments; these markers help accurately localise organ damage. …”
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Electrochemical Sensor for Cu(II) Based on Carbon Nanotubes Functionalized with a Rationally Designed Schiff Base
Published 2025-01-01“…This work proposes a new strategy for the electrochemical quantification of Cu(II) using glassy carbon electrodes (GCEs) modified with a nanohybrid of multiwall carbon nanotubes (MWCNTs) non-covalently functionalized with a rationally designed Schiff base containing different groups (SB-dBA). …”
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Role of body anthropometry in severe asthmatic patients: Evidences from the Severe Asthma Network in Italy (SANI) registry
Published 2025-05-01“…Demographic, clinical and functional features were compared, according to body mass index (BMI). …”
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