Pharmacokinetics of post-transplant cyclophosphamide and its associations with clinical outcomes in pediatric haploidentical hematopoietic stem cell transplantation by Kyung Taek Hong, Sungyeun Bae, Yoon Sunwoo, Juyeon Lee, Hyun Jin Park, Bo Kyung Kim, Jung Yoon Choi, Joo-Youn Cho, Kyung-Sang Yu, Jaeseong Oh, Hyoung Jin Kang

“…The simulated pharmacokinetic profiles of cyclophosphamide and its metabolites were compared among different age groups using real-world data. Results A total of 15 pediatric patients (median age at HSCT 9.6 years, range 1.6–16.8) were enrolled. …”
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Experience with the Use of Thio/Mel Conditioning Regimen Prior to Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma by SV Gritsaev, II Kostroma, AA Zhernyakova, IM Zapreeva, EV Karyagina, ZhV Chubukina, SA Tiranova, IS Martynkevich, SS Bessmeltsev, AV Chechetkin

“…In multiple myeloma (MM) treatment a single autologous hematopoietic stem cell transplantation (auto-HSCT) is preceded by conditioning regimens aimed at intensifying cytoreductive effect. …”
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Tacrolimus exposure during the three-month period following allogeneic stem cell transplantation predicts overall survival by Alzbeta Zavrelova, Katerina Zibridova, Jakub Radocha, Eva Cermakova, Petra Rozsivalova, Pavel Zak, Benjamin Visek, Miriam Lanska, Jana Stevkova, Sara Merdita, Ondrej Slanar, Martin Sima

“…ObjectivesThe objective of this study was to investigate the relationship between both short-term and long-term tacrolimus exposure and overall survival after allogeneic stem cell transplantation and to propose individualized tacrolimus dosing based on the population pharmacokinetic model.Study designTacrolimus exposure during the first 3 months of therapy after transplantation was calculated using therapeutic drug monitoring data from all patients who underwent allogeneic stem cell transplantation from 2016 to 2018. …”
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Repeat-dose toxicity of human umbilical cord mesenchymal stem cells via subcutaneous injection in NOG mice by Lijuan Xia, Jinjin Shao, Qian Yang, Chengda Zhang, Zhiqi Xie, Linying Wang, Cong Xu, Siming Zhang, Jing Liu, Jing Liu, Fang Liu, Fang Liu, Yuhua Shi, Liqiang Gu, Xiaobo Lin, Jiahong Wang, Ying Chen, Yunxiang Chen, Xin Pan, Feifei Wu, Ruolang Pan, Jinfeng Liang, Lijiang Zhang, Lijiang Zhang

“…However, safety data for subcutaneous injection of stem cells remain limited. …”
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CD36 enrichment in HER2-positive mesenchymal stem cells drives therapy refractoriness in breast cancer by Lorenzo Castagnoli, Alma Franceschini, Valeria Cancila, Matteo Dugo, Martina Bigliardi, Claudia Chiodoni, Paolo Toneguzzo, Viola Regondi, Paola A. Corsetto, Filippo Pietrantonio, Serena Mazzucchelli, Fabio Corsi, Antonino Belfiore, Andrea Vingiani, Giancarlo Pruneri, Francesca Ligorio, Mario P. Colombo, Elda Tagliabue, Claudio Tripodo, Claudio Vernieri, Tiziana Triulzi, Serenella M. Pupa

“…Intratumor expression of CSC subsets was evaluated via multiplex immunostaining and immunolocalization analysis. Results Molecular data demonstrated that CD36 is significantly upmodulated on treatment in therapy resistant HER2 + BC patients and its expression levels in BC cells is correlated with FA uptake. …”
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VPA Enhances Pulp Regeneration by Regulating LPS-Induced Human Dental Pulp Stem Cells Odontogenic Differentiation by Zhihua Wang, Minghao Wang, Zhirong Luo, Yi Fu, Xiaomiao Zhu, Dongyu Li, Wenkai Jiang, Xiaogang Cheng, Chengxiong Cai, Xiaoru Zhu, Paul R. Cooper, Shengchao Wang, Wenxi He

“…In vitro, the effect of VPA on the odontogenic differentiation of human dental pulp stem cells (hDPSCs) was assessed using mineralization assays following lipopolysaccharide (LPS) exposure. …”
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Safety and efficacy of amnion-derived mesenchymal stem cells (AM01) in patients with steroid-refractory acute graft-versus-host disease after allogeneic haematopoietic stem cell tr... by Hiroki Nishikawa, Shunsuke Ohnishi, Hiroshi Hayashi, Rika Okamoto, Kenichi Yamahara, Toshiyuki Isoe, Norihiro Sato, Akiko Hamada, Toshihiro Soma, Masaya Okada, Satoshi Yoshihara, Kyoko Yoshihara, Kazuhiro Ikegame, Hiroya Tamaki, Katsuji Kaida, Takayuki Inoue, Yuko Ohsugi, Hiroaki Iijima, Daigo Hashimoto, Takanori Teshima, Hiroyasu Ogawa, Yoshihiro Fujimori

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Private Data Leakage in Federated Contrastive Learning Networks by Kongyang Chen, Wenfeng Wang, Zixin Wang, Yao Huang, Yatie Xiao, Wangjun Zhang, Zhipeng Li, Zhefei Guo, Zhucheng Luo, Lin Yin, Haiyan Mai, Xiaoying Wang, Qintai Yang

“…Nonetheless, FCL is susceptible to local data leakage risks, such as membership information leakage, stemming from its distributed nature, an aspect often overlooked in current solutions. …”
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Modeling integration site data for safety assessment with MELISSA by Tsai-Yu Lin, Giacomo Ceoldo, Kimberley House, Matthew Welty, Thao Thi Dang, Denise Klatt, Christian Brendel, Michael P. Murphy, Kenneth Cornetta, Danilo Pellin

“…We characterized the IS profile of a lentiviral vector on Mesenchymal Stem Cells (MSCs) and compared it with that of Hematopoietic Stem and Progenitor Cells (HSPCs). …”
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A Framework for Rapidly Prototyping Data Mining Pipelines by Flavio Corradini, Luca Mozzoni, Marco Piangerelli, Barbara Re, Lorenzo Rossi

“…With the advent of Big Data, data mining techniques have become crucial for improving decision-making across diverse sectors, yet their employment demands significant resources and time. …”
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Fostering the Development of Earth Data Science Skills in a Diverse Community of Online Learners: A Case Study of the Earth Data Science Corps by Nathan A. Quarderer, Leah Wasser, Anne U. Gold, Patricia Montaño, Lauren Herwehe, Katherine Halama, Emily Biggane, Jessica Logan, David Parr, Sylvia Brady, James Sanovia, Charles Jason Tinant, Elisha Yellow Thunder, Justina White Eyes, LaShell Poor Bear/Bagola, Madison Phelps, Trey Orion Phelps, Brett Alberts, Michela Johnson, Nathan Korinek, William Travis, Naomi Jacquez, Kaiea Rohlehr, Emily Ward, Elsa Culler, R. Chelsea Nagy, Jennifer Balch

“…Using a Rasch modeling approach, we found that participating in the EDSC program had a significant impact on undergraduate learners’ comfort and confidence with technical and nontechnical data science skills, as well as their science identity and sense of belonging in science, two critical aspects of recruiting and retaining members of underrepresented groups in STEM. …”
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Secondary use of routinely collected administrative health data for epidemiologic research: Answering research questions using data collected for a different purpose by Scott D. Emerson, Taylor McLinden, Paul Sereda, Amanda M. Yonkman, Jason Trigg, Sandra Peterson, Robert S. Hogg, Kate A. Salters, Viviane D. Lima, Rolando Barrios

“…Many of these challenges stem from the researcher's lack of control over the quality and consistency of data collection, and - furthermore - a lessened understanding of the data being analyzed. …”
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Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. by Christopher Heylman, Rupsa Datta, Agua Sobrino, Steven George, Enrico Gratton

“…In this study, the electrophysiological effects of β-adrenergic drugs, propranolol and isoproterenol, on cardiomyocytes derived from human induced pluripotent stem cells (hiPS-CM) were assessed. The electrophysiological data were collected using high temporal resolution 2-photon microscopy of voltage sensitive dyes as a reporter of membrane voltage. …”
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Post-traumatic growth experience with kinship hematopoietic stem cells transplantation in patients with aplastic anemia: A qualitative study. by Xinrui Huang, Yan Xu, Yue Pan, Menghua Ye, Ting Liu, Min Xu

“…Interpretative phenomenological analysis was used to collect verbal and nonverbal data through purposive sampling.<h4>Results</h4>By analyzing the interview data on the post-traumatic growth experiences of six aplastic anemia kinship hematopoietic stem cell transplant patients and three medical staff, four themes and nine sub-themes were developed.…”
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Development of Innovative Ethno-Vlog Media Based on Ethno-STEM to Equip Students' Creativity and Realize UNNES Conservation Vision by Sudarmin Sudarmin, Langlang Handayani, Sarwi Sarwi, Risa Dwita Hardianti, Norma Eralita, Woro Sumarni, Fonny Dameaty Hutagalung

“…The analysis of the research data and discussion can be concluded that (a) the Ethno-vlog product has been produced by students taking Ethno-science courses and local intelligence with interesting categories; (b) the student's conservation character and creativity can be developed with the creation and learning of a STEM-based Ethno-vlog project; and (c) students' responses to the tasks of the STEM-based Ethno-vlog project are in good categories. …”
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Cell type–dependent role of transforming growth factor-β signaling on postnatal neural stem cell proliferation and migration by Kierra Ware, Joshua Peter, Lucas McClain, Yu Luo

“…Our data showed that exogenous transforming growth factor-β treatment led to inhibition of the proliferation of primary neural stem cells while stimulating their migration. …”
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Synergistic Improvement in Children with Cerebral Palsy Who Underwent Double-Course Human Wharton’s Jelly Stem Cell Transplantation by Xiaojun Fu, Rongrong Hua, Xiaodong Wang, Peishen Wang, Long Yi, Aixue Yu, Jing Yang, Yan Li, Yihua An

“…Our previous studies confirmed that human Wharton’s Jelly stem cell (hWJSC) transplantation improved motor function in children with spastic cerebral palsy (CP). …”
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Risk factors analysis and predictive model construction of infection after pterygium excision combined with limbal stem cell transplantation by WU Jing，TIAN Jingjing，MENG Jie

“…Patients were divided into infected group（13 cases）and uninfected group（107 cases）according to whether they had secondary infection after surgery. The general data and clinical data of the two groups were collected and analyzed, and the influencing factors of infection were analyzed through multivariate logistic regression analysis. …”
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Long-Term Outcomes in Patients with Plasma Cell Myeloma Following High-Dose Chemotherapy with Autologous Stem Cell Transplantation by Eva Oehlbaum, Alexander Ring, Suraj Balakrishna, Antonia Müller

“…In patients with follow-up data of at least 5 years (n=174), the estimated 5-year OS rate was 68.4%. …”
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Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain by Lea Jessica Berg, Chung Ku Lee, Hideaki Matsumura, Anke Leinhaas, Rachel Konang, Ali H. Shaib, Pedro Royero, Julia Schlee, Chao Sheng, Heinz Beck, Martin Karl Schwarz, Nils Brose, Jeong Seop Rhee, Oliver Brüstle

“…Abstract Transplantation of induced pluripotent stem cell-derived neural cells represents a promising strategy for treating neurodegenerative diseases. …”
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