miRNA changes associated with differentiation of human embryonic stem cells into human retinal ganglion cells by Maryam Esmaeili, Daniel A. Smith, Ben Mead

“…Using a CRISPR/Cas9-based reporter embryonic stem cell line, human RGC were generated and their miRNA profile characterized using NanoString miRNA assays. …”
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Enhancing STEM Learning through the Activated Classroom Teaching Pedagogy: A Case Study in Primary Mathematics by Desmond Wesley Govender, Daniel Adeboye, Irene Govender

“…Students often exhibit a strong aversion to STEM subjects, particularly Mathematics, leading to poor performance. …”
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Brain stem’s damage in patients with acoustic neuromas and subtentorial meningiomas according to Proton Magnetic Resonance Spectroscopy by G. I. Moisak, V. Ye. Olyushin, V. A. Fokin, A. V. Okolzin, L. N. Maslova

“…Extracerebral tumors of posterior fossa often lead to dysfunction of the brain stem, however the degree of brain stem’s damage is determined most often on the basis clinical data only. …”
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Arenobufagin suppresses the progression of early-stage hepatocellular carcinoma by inhibiting EpCAM-mediated tumor stemness by Lijuan Deng, Lifang Zou, Chunhong Zhou, Fuqin Yang, Fen Ouyang, Yingru Zhu, Huihui Cao, Min Hu, Xiaoshen Zhang, Junshan Liu

“…Furthermore, arenobufagin inhibited the viability of Hep3B and Huh7 cells with IC 50 values of 36.4 nM and 123.4 nM after 72 h of treatment, respectively. Molecular docking data further indicated that arenobufagin binds EpCAM. …”
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Mesenchymal Stem Cell Therapy for the Treatment of Vocal Fold Scarring: A Systematic Review of Preclinical Studies. by Vibe Lindeblad Wingstrand, Christian Grønhøj Larsen, David H Jensen, Kristian Bork, Lars Sebbesen, Jesper Balle, Anne Fischer-Nielsen, Christian von Buchwald

“…<h4>Data sources</h4>PubMed, Embase, the Cochrane Library and Google Scholar were searched.…”
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The Effect of Stem Integrated Project Based Learning Model on Students' Critical Thinking Ability in Geography Subjects by Dwi Raudatul Jannah, Alfi Sahrina, Dwiyono Hari Utomo

“…It is concluded that the STEM-integrated Project Based Learning model has a significant effect on critical thinking skills.…”
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Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation. by Jinyue Liao, Hoi Ching Suen, Alfred Chun Shui Luk, Lele Yang, Annie Wing Tung Lee, Huayu Qi, Tin-Lap Lee

“…Spermatogonial stem cells (SSC), the foundation of spermatogenesis and male fertility, possess lifelong self-renewal activity. …”
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Transcriptomic characterization of maturing neurons from human neural stem cells across developmental time points by Kimia Hosseini, Gaëtan Philippot, Sara B. Salomonsson, Andrea Cediel-Ulloa, Elnaz Gholizadeh, Robert Fredriksson

“…In this study, human embryonic stem cell (H9 cell line) was differentiated into neural stem cells and subsequently matured into neurons over 30 days. …”
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Enhancing middle school science education: Evaluating a competency-based STEM training program for teachers by Mohamed A. Shahat, Mahmoud M. Emam, Marwa Alhinai, Ehab M. Omara, Nabil Alhabsi, Khoula Alhosni, Amur Al-Yahmedi, Mohammed Al-Amri, Sameh S. Ismail, Sulaiman M. Al-Balushi

“…Grounded in a quasi-experimental design, the study involved 48 junior high school teachers in Oman, randomly assigned to experimental (n = 24) or control (n = 24) groups. Data were analyzed using t-test and MANOVA, with pre- and post-test scores from the Teachers' PCK of STEM Test (TPCKST), revealing significant improvements (p < 0.05) in PCK among teachers in the experimental group compared to the control group. …”
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Efficacy of therapeutic strategies on thrombocytopenia after hematopoietic stem cell transplantation—an evidence-based meta-analysis by Wenxi Hua, Yunyi Chen, Jiaqian Qi, Xiaofei Song, Meng Zhou, Yue Han

“…Background: Thrombocytopenia is a common complication following hematopoietic stem cell transplantation, and there is currently no standardized therapeutic approach for its management. …”
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Same Classroom, Different Reality: Secondary School Students’ Perceptions of STEM Lessons—A Pioneering Study by Lukas Ketscher, Heidrun Stoeger, Wilma Vialle, Albert Ziegler

“…(3) Explanatory validation strategy: Do gender differences also appear in the perception of STEM lessons? Data were collected via an online questionnaire. …”
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BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis by Ross C. Gruber, Gregory S. Wirak, Anna S. Blazier, Lan Lee, Michael R. Dufault, Nellwyn Hagan, Nathalie Chretien, Michael LaMorte, Timothy R. Hammond, Agnes Cheong, Sean K. Ryan, Andrew Macklin, Mindy Zhang, Nilesh Pande, Evis Havari, Timothy J. Turner, Anthony Chomyk, Emilie Christie, Bruce D. Trapp, Dimitry Ofengeim

“…Finally, we demonstrate that in MS tissue BTK is expressed in B-cells and microglia, with increased levels in lesions. Our data provide rationale for targeting BTK in the CNS to diminish neuroinflammation and disability accumulation.…”
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Synergistic Integration of Mesenchymal Stem Cells and Hydrostatic Pressure in the Expansion and Maintenance of Human Hematopoietic/Progenitor Cells by Yun Gyeong Kang, Jee-Yeong Jeong, Tae-Hee Lee, Ho Sup Lee, Jung-Woog Shin

“…Ex vivo expansion of hematopoietic stem/progenitor cell (HSPC) has been investigated to improve the clinical outcome of HSPC transplantation. …”
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Transcriptome-aligned metabolic profiling by SERSome reflects biological changes following mesenchymal stem cells expansion by Xinyuan Bi, Bin Ma, Wei Liu, Wei-Qiang Gao, Jian Ye, Hanyu Rao

“…Abstract Background Mesenchymal stem cells (MSCs) are widely applied in the treatment of various clinical diseases and in the field of medical aesthetics. …”
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Clinical Applicability of Stem Cell Therapy in Dental Diseases: A Systematic Review of Available Clinical Trials by Atena Shiva, Shahin Arab, Maziar Khatami, Nika Rezaeikalantari, Rezvan Yazdian, Parastoo Namdar

“…Results: Overall, 22 articles with 400 study patients were found and used for qualitative data synthesis. Findings showed that various stem cells with different origins can be used for cell therapy of various dental diseases such as pulp necrosis, traumatic dental injuries, maxillofacial bony defects, impacted third molars, etc. …”
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Design and Experimental Validation of Stem-Clamping-and-Pull-Out-Type Pepper Plug Seedling-Picking Mechanism by Zhenhua Lin, Xiao Li, Hao Sun, Maile Zhou, Jianjun Yin, Jijia He, Daqing Yin

“…The measured angles of the end effector at four key postures were highly consistent with simulation and high-speed camera data, with all key posture errors less than 1°. These results demonstrate the mechanism’s high accuracy, efficiency, and reliability.…”
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Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer. by Roy Blum, Rashmi Gupta, Patricia E Burger, Christopher S Ontiveros, Sarah N Salm, Xiaozhong Xiong, Alexander Kamb, Holger Wesche, Lisa Marshall, Gene Cutler, Xiangyun Wang, Jiri Zavadil, David Moscatelli, E Lynette Wilson

“…<h4>Conclusions/significance</h4>Our data indicate that adult prostate stem or progenitor cells may acquire characteristics of self-renewing primitive fetal prostate cells during oncogenesis and suggest that aberrant activation of components of prostate stem cell pathways may contribute to the development of prostate tumors.…”
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Identification of Stem-Like Cells in Atrial Myxoma by Markers CD44, CD19, and CD45 by Xianghe Song, Danni Liu, Jian Cui, Manqian Zhou, Hui Wang, Na Liu, Xin Qi, Zongjin Li

“…In this study, we investigated whether stem-like cells could contribute to the atrial cardiac myxoma. …”
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Development of PjBL-based Canva Teaching Media with STEM approach to Improve Students' Critical Thinking by Endang Palupi, Puguh Karyanto, Bowo Sugiharto

“…The ADDIE model has five stages, namely Analysis, Define, Design, Implement, and Evaluate. The data analysis used in this research is the RASCH model, Anacova test, and t-test. …”
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Identification of stable housekeeping genes for induced pluripotent stem cells and -derived endothelial cells for drug testing by Sheena L. M. Ong, Hans J. Baelde, David G. P. van IJzendoorn, Judith V. M. G. Bovée, Karoly Szuhai

“…Abstract There are no validated housekeeping genes in induced pluripotent stem cells (iPSC) and derived endothelial iPSC (iPSC-EC). …”
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