The Proresolving Lipid Mediator Maresin1 Alleviates Experimental Pancreatitis via Switching Macrophage Polarization by Yingying Lu, Guotao Lu, Lin Gao, Qingtian Zhu, Jing Xue, Jingzhu Zhang, Xiaojie Ma, Nan Ma, Qi Yang, Jie Dong, Weijuan Gong, Weiqin Li, Zhihui Tong

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Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study by Ken-ei Sada, Shuhei Yoshida, Kenji Saito, Yuya Fujita, Eisuke Inoue, Kiyoshi Migita, Naoki Matsuoka, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara, Keisuke Nishimura, Takashi Kida, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Tomoyuki Asano, Shotaro Ogawa, Jumpei Fukita, Yusuke Matsuo, Takahisa Onishi

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Blood immunomap for prediction of responses to anti-PD-1 immunotherapy in metastatic non-small cell lung cancer by Maria Semitekolou, Nikolaos Paschalidis, Domenico Lo Tartaro, Aikaterini Tsitsopoulou, Panagiota Stamou, Alexandros Mavroudis, Effrosyni Markaki, Athina Varveri, Ioannis Morianos, Matthieu Lavigne, Charalampos Fotsitzoudis, Sofia Magkouta, Konstantina Dede, Ioannis Kalomenidis, Konstantinos Samitas, Konstantinos Potaris, Andrea Cossarizza, Dimitrios Mavroudis, Sara De Biasi, Panayiotis Verginis

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Identification of intratumoral microbiome-driven immune modulation and therapeutic implications in diffuse large B-cell lymphoma by Zheng Yijia, Xiaoyu Li, Lina Ma, Siying Wang, Hong Du, Yun Wu, Jing Yu, Yunxia Xiang, Daiqin Xiong, Huiting Shan, Yubo Wang, Zhi Wang, Jianping Hao, Jie Wang

“…Methods Transcriptomic and microbiome data from 48 DLBCL patients were obtained from public databases. …”
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Abstract 054: Transradial Thrombectomy Using "Sheathless PV" Guide Catheter in Armenia: Three‐Year Institutional Experience in 103 Cases by David Sahakyan, Anna Isahakyan, David Marqaryan, Aleksan Petrosyan, Mikayel Grigoryan

“…The interest in its use specifically for TRA stemmed from competitive price (∼ $100 per catheter vs ), hydrophilic coating of the outer shaft, as well as lack of femoral closure devices in the country. …”
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Políticas de cuotas en el empleo público: desafíos para la inclusión de personas trans en Aragón by Julieta Vartabedian, Maribel Blázquez Rodríguez, José Luis Gómez, J. Ignacio Pichardo

“…An analysis of the opinions of public administration employees in Aragón reveals that this resistance largely stems from a lack of understanding of the structural barriers faced by trans people. …”
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ANALYTICAL VALIDATION OF A 10-COLOR FLOW CYTOMETRY PANEL FOR ASSESSMENT OF MEASURABLE RESIDUAL DISEASE OF ACUTE MYELOID LEUKEMIA by AR Severino, CM Bertolucci, JFDS Tosi, MRV Ikoma-Colturato

“…Infinicyt (Cytognos™) software was used for data analysis. Statistical analysis: R software (v 4.1.2) and Excel were used for statistical analysis, considering a p value ≤ 0.05 as significant. …”
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Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study by Kazuaki Chayama, Yuji Takaeko, Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Takayuki Yamaji, Takahiro Harada, Yiming Han, Haruki Hashimoto, Yasuki Kihara, Eisuke Hida, Chikara Goto, Yoshiki Aibara, Farina Mohamad Yusoff, Shinji Kishimoto, Ayumu Nakashima, Yukihito Higashi

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Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features by Peter Novak, MD, PhD, David M. Systrom, MD, Sadie P. Marciano, PA-C, Alexandra Witte, PA-C, Arabella Warren, MD, PhD, Donna Felsenstein, MD, Matthew P. Giannetti, MD, Matthew J. Hamilton, MD, Jennifer Nicoloro-SantaBarbara, PhD, Mariana Castells, MD, Khosro Farhad, MD, David M. Pilgrim, MD, William J. Mullally, MD, Mark C. Fishman, MD, Jeff M. Milunsky, MD, Aubrey Milunsky, MD, Joel Krier, MD

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Evaluating main gas emission and energy consumption economy during tobacco leaf curing life cycle based on clean energy by Yinlong Zhu, Yonglei Jiang, Yi Chen, Jiaen Su, Ming Li, Qiongfen Yu, Zhenhua Gu, Jianhuan Deng, Sheng Tang, Zhihao Song, Xudong Wang, Bo Ma

“…Data analysis showed that CO2 emission concentration of each energy roaster reached the highest in all stages under standard working conditions, and CO2 emission of biomass roaster reached 550.68 kg in the 10th stage, while there was no SO2 emission from alcohol-based and natural gas roasters. …”
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The effects of postponing BCG vaccination on the risk of BCG-related complications among patients with severe combined immunodeficiency disease in Saudi Arabia by Amal Aldhaheri, Ohoud Alyabes, Ohoud Alyabes, Suliman Aljumaah, Suliman Aljumaah, Raghad Alhuthil, Raghad Alonazi, Shefa Alamoudi, Mohammed Alsuhaibani, Mohammed Alsuhaibani, Salem Alghamdi, Salem Alghamdi, Esam A. Albanyan, Esam A. Albanyan, Sami Al-Hajjar, Sami Al-Hajjar, Reem Mohammed, Rand Arnaout, Sultan Albuhairi, Nora Alrumayyan, Bandar Al-Saud, Bandar Al-Saud, Hamoud Al-Mousa, Hamoud Al-Mousa

“…The incidence of BCG-related complications dropped significantly after the policy change, from 46.1% in Era 1 to 2.6% in Era 2. Patients required stem cell transplantation and a median of 17.6 months of anti-mycobacterial therapy. …”
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Restricting SLC7A5-mediated Leucine uptake in T cells prevents acute GVHD and maintains GVT response by Nieves Fernández-Gallego, Blanca Anega, Susana Luengo-Arias, Maider Bizkarguenaga, Rubén Gil-Redondo, Nieves Embade, Laura Navarrete-Arias, Marta Ramírez-Huesca, Emigdio Álvarez-Corrales, Sara G Dosil, Raquel Castillo-González, Amelia Rojas-Gomez, Inés Espeleta, Sara Martínez-Martínez, Arantzazu Alfranca, Virginia G de Yebenes, Noa Beatriz Martín-Cófreces, Julián Aragonés, Pilar Martin, Oscar Millet, Francisco Sánchez-Madrid, Danay Cibrian

“…On the contrary, L-Leu removal reduced mTORC1 and completely blocked glycolysis but preserved mitochondrial function, favoring the generation of central memory responses and expression of stemness marker TCF1. In addition, our metabolomics data underscores the L-Leu-derived metabolite β-hydroxybutyrate as an important marker for SLC7A5-dependent allogenic T cell expansion in aGVHD.…”
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Effect of Growth Period Duration on Faba Bean (Vicia faba L.) Varieties with Conventional and Multivariate Methods and Sensory Evaluation of Green Seed Quality by Arman Kazemi, Peyman Sharifi, Nosaibeh Nezamdust

“…The effect of sowing date was significant on all traits except stems per plant. The interaction effect of two factors was also significant on all traits except days to emergence and stems per plant. …”
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Investigating POU3F4 in cancer: Expression patterns, prognostic implications, and functional roles in tumor immunity by Weiwei Chen, Yaya Ji, Rui Wang, Ruijie Ji, Yujian Lin, Yuhang Wu, Lehan Liu, Tianle Sha, Wen Li, Lei Zhang, Longfei Yang, Xinhua Zhang, Jianxiang Song

“…Research has demonstrated that POU3F4 is integral to various cancers, in addition to its significance in inner ear development, pancreatic differentiation, as well as neural stem cell differentiation. Nevertheless, comprehensive pan-cancer analyses focusing on POU3F4 remain limited. …”
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Novel perceptions and insights into the rare hematologic malignancy of acute megakaryocytic leukemia: a multicenter clinical retrospective study by Yuan Liu, Yanquan Liu, Xiaojun Chen, Yue Yin, Zhenyuan Xu, Jiachen Xie, Jianzhen Shen, He Huang, Huidong Guo

“…Patients with AMKL might benefit from induced remission chemotherapy combined with novel targeted therapy. Hematopoietic stem cell transplantation should be carried out as soon as possible after the first CR induced by standard chemotherapy to optimize the prognosis.…”
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IL‐2Rα is a potential biomarker for heart failure diagnosis of patients with end‐stage renal disease and haemodialysis by Bingya Lv, Zhe Wang, Ya Suo, Shuai Shao, Meng Yuan, Yue Zhang, Lihua Wang, Guangping Li, Qiankun Bao

“…Clinical characteristics and echocardiographic data were collected and analysed. We measured the plasma of 44 cytokines to investigate their correlation with cardiac function and their potential as HF biomarkers. …”
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Dynamics of minimal residual disease and its clinical implications in multiple myeloma: A retrospective real-life analysis by Weiling Xu, Xinyue Liang, Shanshan Liu, Xingcheng Yi, Mengru Tian, Tingting Yue, Yingjie Zhang, Yurong Yan, Maozhuo Lan, Mengtuan Long, Nan Zhang, Jingxuan Wang, Xiaoxiao Sun, Rui Hu, Yufeng Zhu, Xintian Ma, Yue Cheng, Jiayi Xu, Yun Dai, Fengyan Jin

“…Methods: We retrospectively analysed the data of patients with newly diagnosed MM (NDMM) who had flow cytometry-based MRD tests at multiple time points after initiation of therapy. …”
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Long‐term interventions by conservation and development projects support successful recovery of tropical peatlands in Amazonia by Eurídice N. Honorio Coronado, Julio Grández Rios, Jhon delÁguila Pasquel, Gerardo Flores Llampazo, Cesar J. Córdova Oroche, José Reyna Huaymacari, C. Gabriel Hidalgo Pizango, Luis Freitas Alvarado, Ulises Pipa Murayari, Gonzalo Isla Reátegui, Chris López Álvarez, Eva Loja Aleman, Emiliana Isasi‐Catalá, Joaquín Gutierrez‐Sotelo, Frederick C. Draper, Margarita delAguila Villacorta, Timothy R. Baker, Dennis delCastillo Torres, Kenton de laCruz Gamarra, Daniel Escobedo Guerra, Ian T. Lawson, Manuel Martín Brañas, Estela P. Martinez Gonzales, Jacqueline Ramirez Chávez, Katherine H. Roucoux

“…Recovery of M. flexuosa populations was supported by local perceptions of increases in stand productivity, improved values of most indicators within managed stands compared to reference data from unmanaged stands in the region, and continuous recovery of degraded stands over time following the adoption of climbing by both communities. …”
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hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation by Ian Weidling, Christina N. Preiss, Sarah E. Chancellor, Gyan Srivastava, Lauren Gibilisco, Gen Lin, Melanie Shackett Brennan, Janice Lee, Lindsay M. Roth, Olga Morozova, Kyong Nyon Nam, Nehal R. Patel, Qing Liu, J. K. Thomas, Peter Reinhardt, Ruven Wilkens, Dagmar E. Ehrnhoefer, Andreas Striebinger, Stefan Barghorn, Christina Xanthopoulos, Marie-Theres Weil, Sandra Biesinger, Miroslav Cik, Nandini Romanul, Kiran Yanamandra, Alessandra M. Welker, Jessica Wu, Laura Gasparini, Jan Stöhr, Xavier Langlois, Justine D. Manos

“…Using our recently established platform for inducing endogenous Tau aggregation in human induced pluripotent stem cell (hiPSC)-derived cortical excitatory neurons via application of AD brain-derived exogenous Tau aggregates, we explored whether Tau aggregates preferentially induce aggregation in specific neuronal subtypes. …”
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Donor-derived CARCIK-CD19 cells engineered with Sleeping Beauty transposon in acute lymphoblastic leukemia relapsed after allogeneic transplantation by Federico Lussana, Chiara F. Magnani, Stefania Galimberti, Giuseppe Gritti, Giuseppe Gaipa, Daniela Belotti, Benedetta Cabiati, Sara Napolitano, Silvia Ferrari, Alex Moretti, Chiara Buracchi, Gian Maria Borleri, Benedetta Rambaldi, Giuliana Rizzuto, Anna Grassi, Muriel Paganessi, Cristian Meli, Sarah Tettamanti, Giulia Risca, Giulia Pais, Giulio Spinozzi, Fabrizio Benedicenti, Giovanni Cazzaniga, Chiara Capelli, Elisa Gotti, Martino Introna, Josée Golay, Eugenio Montini, Adriana Balduzzi, Maria Grazia Valsecchi, Giuseppe Dastoli, Alessandro Rambaldi, Andrea Biondi

“…Integration site analysis after infusion showed a high clonal diversity. These data demonstrated that SB-engineered CAR-T cells are safe and induce durable remission in heavily pretreated patients with BCP-ALL relapsed after alloHSCT. …”
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