CAR’TCR-T cells co-expressing CD33-CAR and dNPM1-TCR as superior dual-targeting approach for AML treatment by Karin Teppert, Isabella Elias Yonezawa Ogusuku, Caroline Brandes, Vera Herbel, Nora Winter, Niels Werchau, Svetlana Khorkova, Christian Wöhle, Nojan Jelveh, Kevin Bisdorf, Boris Engels, Thomas Schaser, Kathleen Anders, Annette Künkele, Dominik Lock

“…Acute myeloid leukemia (AML), a fast-progressing hematological malignancy affecting myeloid cells, is typically treated with chemotherapy or hematopoietic stem cell transplantation. However, approximately half of the patients face relapses and 5-year survival rates are poor. …”
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Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. by Christopher A Maxwell, Javier Benítez, Laia Gómez-Baldó, Ana Osorio, Núria Bonifaci, Ricardo Fernández-Ramires, Sylvain V Costes, Elisabet Guinó, Helen Chen, Gareth J R Evans, Pooja Mohan, Isabel Català, Anna Petit, Helena Aguilar, Alberto Villanueva, Alvaro Aytes, Jordi Serra-Musach, Gad Rennert, Flavio Lejbkowicz, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Carla B Ripamonti, Bernardo Bonanni, Alessandra Viel, Anna Allavena, Loris Bernard, Paolo Radice, Eitan Friedman, Bella Kaufman, Yael Laitman, Maya Dubrovsky, Roni Milgrom, Anna Jakubowska, Cezary Cybulski, Bohdan Gorski, Katarzyna Jaworska, Katarzyna Durda, Grzegorz Sukiennicki, Jan Lubiński, Yin Yao Shugart, Susan M Domchek, Richard Letrero, Barbara L Weber, Frans B L Hogervorst, Matti A Rookus, J Margriet Collee, Peter Devilee, Marjolijn J Ligtenberg, Rob B van der Luijt, Cora M Aalfs, Quinten Waisfisz, Juul Wijnen, Cornelis E P van Roozendaal, HEBON, EMBRACE, Douglas F Easton, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Patricia Harrington, D Gareth Evans, Fiona Lalloo, Rosalind Eeles, Louise Izatt, Carol Chu, Diana Eccles, Fiona Douglas, Carole Brewer, Heli Nevanlinna, Tuomas Heikkinen, Fergus J Couch, Noralane M Lindor, Xianshu Wang, Andrew K Godwin, Maria A Caligo, Grazia Lombardi, Niklas Loman, Per Karlsson, Hans Ehrencrona, Anna von Wachenfeldt, SWE-BRCA, Rosa Bjork Barkardottir, Ute Hamann, Muhammad U Rashid, Adriana Lasa, Trinidad Caldés, Raquel Andrés, Michael Schmitt, Volker Assmann, Kristen Stevens, Kenneth Offit, João Curado, Hagen Tilgner, Roderic Guigó, Gemma Aiza, Joan Brunet, Joan Castellsagué, Griselda Martrat, Ander Urruticoechea, Ignacio Blanco, Laima Tihomirova, David E Goldgar, Saundra Buys, Esther M John, Alexander Miron, Melissa Southey, Mary B Daly, BCFR, Rita K Schmutzler, Barbara Wappenschmidt, Alfons Meindl, Norbert Arnold, Helmut Deissler, Raymonda Varon-Mateeva, Christian Sutter, Dieter Niederacher, Evgeny Imyamitov, Olga M Sinilnikova, Dominique Stoppa-Lyonne, Sylvie Mazoyer, Carole Verny-Pierre, Laurent Castera, Antoine de Pauw, Yves-Jean Bignon, Nancy Uhrhammer, Jean-Philippe Peyrat, Philippe Vennin, Sandra Fert Ferrer, Marie-Agnès Collonge-Rame, Isabelle Mortemousque, GEMO Study Collaborators, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, Sue Healey, kConFab, Mary Helen Barcellos-Hoff, Marc Vidal, Stephen B Gruber, Conxi Lázaro, Gabriel Capellá, Lesley McGuffog, Katherine L Nathanson, Antonis C Antoniou, Georgia Chenevix-Trench, Markus C Fleisch, Víctor Moreno, Miguel Angel Pujana

“…In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal breast tissue and increased risk of developing tumors of basal-like type suggest that BRCA1 regulates stem/progenitor cell proliferation and differentiation. …”
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The Perils of Methanol Exposure: Insights into Toxicity and Clinical Management by Mohammed Alrashed, Norah S. Aldeghaither, Shatha Y. Almutairi, Meshari Almutairi, Abdulrhman Alghamdi, Tariq Alqahtani, Ghada H. Almojathel, Nada A. Alnassar, Sultan M. Alghadeer, Abdulmajeed Alshehri, Mohammed Alnuhait, Omar A. Almohammed

“…Epidemiological data underscore the widespread impact of methanol poisoning, with alarming case fatality rates reported in various countries. …”
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Mineral resource base of Russia’s cobalt: current state and development prospects by G. Yu. Boyarko, L. M. Bolsunovskaya

“…The relevance of this study stems from the need to obtain a comprehensive picture of the state of the cobalt mineral resource base of the Russian Federation. …”
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Regulation of neutrophil migration in acute pulmonary inflammation by extraneuronal α1 gamma-aminobutyric acidA receptors by Anika Fuhr, Robin Roediger, Mariana Simelitidis, Jutta Gamper-Tsigaras, Markus Templin, Michael Kormann, Bernd Antkowiak, Uwe Rudolph, David Köhler, Peter Rosenberger, Kristian-Christos Ngamsri, Franziska M. Konrad

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Comparative analysis of allogeneic hematopoietic cell transplantation in patients with therapy-related and de novo acute promyelocytic leukemia A retrospective study by Satoshi Yamasaki, Masamitsu Yanada, Hiroaki Araie, Takahiro Fukuda, Yoshinobu Kanda, Haruko Tashiro, Naoyuki Uchida, Kazutaka Ozeki, Shuichi Ota, Yasushi Onishi, Noriko Doki, Tatsuo Oyake, Satoru Takada, Masatoshi Sakurai, Yukio Kondo, Hirohisa Nakamae, Toshiro Kawakita, Makoto Onizuka, Yoshiko Atsuta, Takaaki Konuma

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MicroRNAs as novel biomarkers for prenatal fetal congenital heart disease – systematic literature review by Adrianna Kondracka, Paulina Gil-Kulik, Magda Rybak-Krzyszkowska, Jakub Staniczek, Anna Oniszczuk, Bartosz Kondracki

“…However, each of the reviewed studies identified different miRNAs as potential biomarkers. This variability may stem from differences in experimental methodologies, including approaches to miRNA isolation, quantification techniques, and the types of biological materials analyzed. …”
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Assessing sustainable practices and managerial approaches in the hotel industry: A comparative case study by Jitka Vávrová, Lenka Červová, Blanka Brandová, Jorge Pacheco

“…These hotels are direct competitors and have very similar target customers. To collect data, the authors conducted two separate semi-structured, in-depth interviews with the CEOs of both hotels, as well as observations in both establishments and additional interviews with staff. …”
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On Epistemological Boundaries of Turbulence Modeling Revealed through Stokes’ Reserved Stance on Reynolds’ RANS Equations by ZHANG Xiao-feng

“…Through an interdisciplinary investigation combining archival analysis, theoretical fluid dynamics, and philosophy of science, it is revealed that Stokes’ reservations stemmed not from technical negligence but from a profound understanding of the N-S equations’ physical completeness and the inherent epistemological limitations of turbulence closure models. …”
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The Motivations of Citizens to Attend an eHealth Course in the Public Library: Qualitative Interview Study by Lucille Standaar, Adriana Margje Israel, Rosalie van der Vaart, Brigitta Keij, Frank J van Lenthe, Roland Friele, Mariëlle A Beenackers, Lilian Huibertina Davida van Tuyl

“…Themes were identified via a comprehensive thematic data analysis. ResultsThe participants were 51 to 82 years of age (average 73.5, SD 6.6 y) and 14 (70%) participants were female. …”
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PARN Maintains RNA Stability to Regulate Insulin Maturation and GSIS in Pancreatic β Cells by Xiaomei Xie, Xuexue Chen, Chaofan Wang, Longjie Sun, Weiru Yu, Zheng Lv, Shuang Tian, Xiaohong Yao, Fengchao Wang, Deqiang Ding, Juan Chen, Jiali Liu

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Efficacy and Safety of Novel Oral Anti-Cholestatic Agents for Primary Biliary Cholangitis: Meta-Analyses and Systematic Review by Eyad Gadour, Bogdan Miutescu, Hiba Bashir, Abubaker Ali, Salem Alanzi, Abdullah A. Al-Shahrani, Aymen Almuhaidb, Shahed Mohamed, Faisal Abaalkhail, Hadi Kuriry, Mohammed Saad AlQahtani

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Impacted lower third molar classification and difficulty index assessment: comparisons among dental students, general practitioners and deep learning model assistance by Paniti Achararit, Chawan Manaspon, Chavin Jongwannasiri, Promphakkon Kulthanaamondhita, Chumpot Itthichaisri, Soranun Chantarangsu, Thanaphum Osathanon, Ekarat Phattarataratip, Kraisorn Sappayatosok

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Treatment patterns, outcomes and long-term toxicity among patients with Hodgkin’s lymphoma in real world: results of a hospital based registry by E. A. Nikitin, N. N. Sharkunov, V. G. Markaryan, N. A. Lobanova, V. V. Ptushkin

“…Data on treatment results and long-term toxicity of patients with Hodgkin’s lymphoma in Russian Federation are scarce. …”
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The Role of Bosutinib in Chronic Myeloid Leukemia: An Indian Perspective by Mohan Bajranglal Agarwal, Manthanathu Joseph John, Punit Jain, Ashok Kumar Vaid, Ajay Bapna, Maheboob Basade, Palanki Satya Dattatreya, Anupam Chakrapani, Vijay Ramanan, R. Varadarajan, Murali Subramanian, Chirag Aniruddha Shah, Narayanakutty Warrier, Subhaprakash Sanyal, Tyavanagi Shankarmurthy Ashwin, Nagendra Ramanjinappa

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Choice of Myocardial Revascularization Strategy in Elderly Patients with Non-ST Elevation Acute Coronary Syndrome by Sviatoslav A. Kalashnikov, Sergii V. Salo

“…The study had a retrospective, single-center, observational design. Data from 124 patients aged ≥65 years with a diagnosis of non-ST elevation acute coronary syndrome who underwent revascularization by PCI or CABG were analyzed. …”
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Micro-scale genetic structure and genetic variation of Neotricula aperta (Gastropoda: Pomatiopsidae), the intermediate host of Schistosoma mekongi (Digenea: Schistosomatidae) in Ch... by Naruemon Bunchom, Weerachai Saijuntha, Chairat Tantrawatpan, Wanchai Maleewong, Joseph Valencia, Takeshi Agatsuma, Virasack Bounavong, Philippe Buchy, Moritoshi Iwagami

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Snow depth estimation on leadless landfast ice using Cryo2Ice satellite observations by M. Saha, J. Stroeve, J. Stroeve, D. Isleifson, J. Yackel, V. Nandan, V. Nandan, J. C. Landy, H. M. Lam

“…This study is the first assessment of the potential for near-coincident ICESat-2 and Cryosat-2 (Cryo2Ice) snow depth retrievals in a leadless region of the CAA including validation with in situ data. In lieu of sea surface height estimates from leads, snow depths are retrieved using the absolute difference in surface heights (ellipsoidal heights) from ICESat-2 and Cryosat-2 after applying an ocean tide correction based on tidal gauges between satellite passes on 29 April 2022. …”
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“Mulle oli isegi tšau võõras”: vene õppekeelega põhikoolist eestikeelsesse gümnaasiumi by Kristiina Praakli, Aive Mandel

“…The data show that transitioning to a different language of instruction creates uncertainty in adapting to spoken language registers, especially for students with no prior personal experience communicating with Estonian-speaking peers. …”
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Efficacy of Reducing Recurrence of Intrauterine Adhesions and Improving Pregnancy Outcome after Hysteroscopic Adhesiolysis: A Systematic Review and Network Meta-Analysis of Randomi... by Li-jun Lin, Xiao-yong Qiao, Xue-ping Chen, Liang-zhi Xu, Hui Chen

“…Pairwise meta-analyses were performed in random effects model when direct data were available; Network meta-analyses were conducted using “mvmeta” and “network” packages in Stata MP 17.0. …”
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