Cardiac fibroblast-mediated ECM remodeling regulates maturation in an in vitro 3D engineered cardiac tissue by Yongjun Jang, Myeongjin Kang, Yong Guk Kang, Dongtak Lee, Hyo Gi Jung, Dae Sung Yoon, Jongseong Kim, Yongdoo Park

“…However, excessive collagen accumulation reduced functional maturation by limiting contractile efficiency. Our data suggest that ECM remodeling by cardiac fibroblasts is essential for cardiac tissue maintenance and maturation. …”
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Patterns of Health Services and Medicine Utilisation by First‐Generation Pakistani Immigrants in New Zealand by Noor A. Mann, Zain A. Khan, Saima Asghar, Afshan Rani, Nadia Hussain, Sumera S. Akhtar, Susan Heydon, Mudassir Anwar

“…The interviews were audio‐taped and transcribed verbatim. Data were analysed iteratively using an inductive thematic approach. …”
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Panoptic Plant Recognition in 3D Point Clouds: A Dual-Representation Learning Approach with the PP3D Dataset by Lin Zhao, Sheng Wu, Jiahao Fu, Shilin Fang, Shan Liu, Tengping Jiang

“…Leveraging this dataset, we propose the panoptic plant recognition task, which combines semantic segmentation (stems and leaves) with leaf instance segmentation. …”
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No increased drought-related mortality after thinning: a meta-analysis by Julius Willig, Julia Schwarz, Philip Comeau, Henrik Hartmann, Ulrich Kohnle, Josep Maria Espelta, Harri Mäkinen, Roma Ogaya, Mikko Peltoniemi, Josep Penuelas, Brian Roth, Ricardo Ruiz-Peinado, Florian Ruge, Jürgen Bauhus

“…We propose better documentation of thinning trials to improve the data base for systematic reviews.…”
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Single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts reveals transcriptional complexity in the insect central complex by Derek G Epiney, Gonzalo Morales Chaya, Noah R Dillon, Sen-Lin Lai, Chris Q Doe

“…In Drosophila, there are two types of neural stem cells, called Type 1 (T1) and Type 2 (T2) neuroblasts. …”
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Ethanol Administration in Mice Leads to Sex-Specific Changes in the Acetylation of α-Tubulin in the Cerebellum by Abosede Elesinnla, Rehana Khatoon, Nicholas Kleinert, Junfang Wu, Jaylyn Waddell, Tibor Kristian

“…Notably, however, no significant changes were observed in the level of the tubulin deacetylating enzyme, HDAC6, in either sex. Conclusions: Our data demonstrate that these sex differences stem from variations in expression levels of tubulin acetyltransferase (αTAT1), and the rate of ethanol metabolism-related acetyl-CoA production between male and female animals.…”
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In Vitro Culture of Vitrified Immature Mouse Testicular Tissue in The Presence of N-acetylcysteine Antioxidant by Parmiss Nikoosokhan, Zeinab Ghezelayagh, Samira Hajiaghalou, Alireza Alizadeh Moghadam Masouleh, Bita Ebrahimi

“…Background: Cryopreservation of immature testicular tissue is a suitable method for spermatogonial stem cell (SSC) preservation in prepubertal boys, who are at risk of infertility due to cancer treatments. …”
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Serum indicators in functional high-risk multiple myeloma patients undertaking proteasome inhibitors therapy: a retrospective study by Linquan Zhan, Dai Yuan, Xueling Ge, Mei Ding, Jianhong Wang, Xiangxiang Zhou, Xin Wang

“…There was no difference in baseline data between the two groups. Renal impairment (RI, Scr > 2 mg/dL) was common in MM patients and made sense in FHR status. …”
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Epidemiology of Chronic Hepatitis C in First Nations Populations in Canadian Prairie Provinces by Kate P. R. Dunn, Dennis Wardman, Maxim Trubnikov, Chris Sarin, Tom Wong, Hongqun Liu, Samuel S. Lee

“…This non-systematic informative review considers transdisciplinary perspectives, regional data, and published literature connecting context to the disproportionate HCV burden experienced by First Nations populations in the prairie provinces of Canada, and offers examples of participatory and community-led initiatives working toward the elimination of HCV as a public health threat. …”
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Identification and Comprehensive Evaluation of Drought Tolerance in Sorghum During Germination and Seedling Stages by Manhong Wang, Irshad Ahmad, Bin Qin, Lei Chen, Weicheng Bu, Guanglong Zhu, Guisheng Zhou

“…The present results demonstrate that the principal component analysis could represent 77.18% of the data from the original 11 indicators. Total root length, stem diameter, and leaf area were identified as the main evaluation indicators for sorghum seedling drought tolerance. …”
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Crucial role of the Pht1;4 Gene in Sb(V) tolerance and uptake in Arabidopsis thaliana by Ziyi Dong, Mengchang He, Chunye Lin, Wei Ouyang, Xitao Liu

“…The Pht1;1 knockout mutant exhibited a predominant transmembrane absorption mode for Sb(V), while gene expression data show that knocking out either Pht1;1 or Pht1;4 leads to the upregulation of the other gene. …”
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A population-based study on safety and health of drinking Litsea coreana tea (hawk tea) by Han Zhang, Xiyu Pu, Haijun Huang, Qin Huang, Bao Yu, Weiguo Cao, Weiguo Cao, Yong Zhang

“…BackgroundA herbal tea of leaves and stems of Litsea coreana, named Hawk tea locally, has been traditionally consumed in some places in southwestern China. …”
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Integrated multi-omics analysis reveals the immunotherapeutic significance of tumor cells with high FN1 expression in ovarian cancer by Xinyi Zhang, Zhikai Xiahou, Fu Zhao, Qing Wu, Wei Nie, Shouyan Wang

“…Cell stemness was measured using AUCell and CytoTRACE. The gene regulatory network was analyzed using pySCENIC. …”
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Molecular cloning and functional characterization of the shikimate kinase gene from Baphicacanthus cusia by Yuxiang Huang, Yuxiang Huang, Yuxiang Huang, Hexin Tan, Qing Li, Xunxun Wu, Zhiying Guo, Zhiying Guo, Junfeng Chen, Lei Zhang, Yong Diao

“…In this study, the BcSK gene was isolated and cloned from the transcriptome data of B. cusia. The full-length cDNA of BcSK is 1,657 bp, comprising a 265 bp 5’ UTR, a 507 bp 3’ UTR, and an 885 bp ORF encoding 295 amino acids. …”
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Effect of process parameters on the rheological properties of banana (Musa acuminata) fiber and optimization using response surface methodology by Shubham Pandey, R.K. Naik, Vinay Kumar Pandey, Shivangi Srivastava, Gulden Goksen, Shivam Pandey, Sarvesh Rustagi

“…The labor-intensive, time-consuming, and uneconomical nature of manually extracting banana (Musa acuminata) fibers from pseudo-stem sheaths has prompted the exploration of automation as a solution. …”
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A Case of Acute Eosinophilic Leukemia with a Novel PHF6 Mutation by J. J. Lipof, E. J. Huselton, C. S. Zent, A. Evans, B. Zhang, P. G. Rothberg, J. M. Bennett

“…The rarity of this condition has resulted in a paucity of data to guide management. Additional studies are needed to better characterize this entity and inform optimal management strategies to attain a long-term sustained remission in these patients.…”
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Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis by Zhenyi Su, Yanqing Liu, Lin Wang, Wei Gu

“…Moreover, SLC7A11 activity and its protein stability and cellular localization are also modulated upon stress. Patients' data show that SLC7A11 is overexpressed in various types of human cancers, and higher levels of SLC7A11 predict poorer overall survival. …”
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Integrative analysis of mitochondrial-related gene profiling identifies prognostic clusters and drug resistance mechanisms in low-grade glioma by Xiaozan Chang, Yingxuan Huang, Ying Qu, Yu Guo, Wenwen Fan, Haining Zhen

“…In this study, we explored the role of mitochondrial-related genes through consensus clustering analysis using multi-omics data from the TCGA, CGGA, and other independent datasets. …”
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Bridging the Gap Between hiPSC-CMs Cardiotoxicity Assessment and Clinical LVEF Decline Risk: A Case Study of 21 Tyrosine Kinase Inhibitors by Zhijie Wan, Chenyu Wang, Shizheng Luo, Jinwei Zhu, Hua He, Kun Hao

“…<b>Methods</b>: By leveraging high-throughput cardiotoxicity screening with human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), a mechanism-based toxicodynamic (TD) model for TKIs was constructed. …”
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Analysis of pharmacotherapeutic approaches for multiple myeloma and correlated renal and pulmonary impairments: a retrospective real-world registry study in the Greater Gulf Region... by Ayman Alhejazi, Ahmad Alhuraiji, Abdulnaser Nourallah, Abdulrahman Alshehri, Binyam Usman, Ghada ElGohary, Hafiz Malhan, Ibraheem Motabi, Ibraheem Motabi, Khalil Al Farsi, Mohammed Alshuaibi, Mohanad Diab, Mustaqeem Siddiqui, Ruba Yasin Taha, Tarek Abouzeid, Wesam Ahmed, Wesam Ahmed, Ahmed Ramadan Ali, Rasha Ghonema, Sana Faysal Elkhazin, Yousra Moussa, Abdullah M. Alrajhi, Abdullah M. Alrajhi, Magdy Rabea, Yahia Aktham, Nesreen Bawazeer, Ali Ahmed Ali, Mohamed Zahir Chouikrat

“…This study aims to describe the disease characteristics, various treatment regimens, and outcomes among patients with Relapsed/Refractory Multiple Myeloma (RRMM) in the Greater Gulf region.MethodsA regional, retrospective study was conducted in Gulf countries to collect real-world data from the medical records of 148 patients with RRMM who relapsed 1–3 times in the past two years before the data collection period (July 2022 and February 2023).ResultsThe mean age of the study population was 59.4 years, and 64.2% of the participants were male. …”
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