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Circadian rhythms in stem cells and their therapeutic potential
Published 2025-02-01Get full text
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Fostering community discussions and building a toolkit for mental health and wellness in STEM
Published 2024-12-01“…We hope this paper serves as a valuable guide for potential facilitators to initiate conversations about mental health and wellness in their respective STEM spaces.…”
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Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells
Published 2025-01-01“…The objectives of this study are to define a robust and consistent method for the differentiation of induced pluripotent stem cells (iPSCs) into macrophages that can address these needs for recurrent studies with high yields and the potential for gene editing. …”
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The power duo: unleashing cognitive potential through human-AI synergy in STEM and non-STEM education
Published 2025-03-01Get full text
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5
Astrocytes enhance the invasion potential of glioblastoma stem-like cells.
Published 2013-01-01“…Glioblastomas (GBMs) are characterized as highly invasive; the contribution of GBM stem-like cells (GSCs) to the invasive phenotype, however, has not been completely defined. …”
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Therapeutic potential of exosomal lncRNAs derived from stem cells in wound healing: focusing on mesenchymal stem cells
Published 2025-02-01“…Abstract The self-renewal ability and multipotency of stem cells give them great potential for use in wound healing. …”
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Parkinson's Disease and Mesenchymal Stem Cells: Potential for Cell-Based Therapy
Published 2012-01-01“…Cell transplantation is a strategy with great potential for the treatment of Parkinson's disease, and many types of stem cells, including neural stem cells and embryonic stem cells, are considered candidates for transplantation therapy. …”
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The Potential of Mesenchymal Stem Cell-Derived Exosomes to Treat Diabetes Mellitus
Published 2025-01-01“…Consequently, MSC-derived exosomes have attracted attention as a novel treatment for DM as an alternative to stem cell therapy. In this review, we will introduce the potential of MSC-derived exosomes for the treatment of DM by discussing the studies that have used MSC-derived exosomes to treat DM, which have shown therapeutic effects in both type 1 and type 2 DM.…”
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The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer’s Disease
Published 2021-01-01“…Until the invention of induced pluripotent stem cells (iPSCs) in 2006, the bulk of research was carried out using transgenic animal models that offered little promise in their ability to translate well from benchtop to bedside, creating a bottleneck in the development of therapeutics. …”
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Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair
Published 2018-01-01“…This review summarizes current advances in dental pulp stem cells (DPSCs) and their potential applications in the nervous diseases. …”
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The metaphysical, ethical and theological musings on embryonic stem cells
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Adipose-derived stem cell exosomes: mechanisms and therapeutic potentials in wound healing
Published 2025-06-01“…Among the emerging therapeutic strategies, adipose-derived stem cell exosomes (ADSC-Exos) attract significant attention due to their potent regenerative capabilities. …”
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Very small embryonic-like stem cells (VSELs) on the way for potential applications in regenerative medicine
Published 2025-03-01“…Our group purified these rare cells, naming them very small embryonic-like stem cells (VSELs). With their broad differentiation potential, VSELs have emerged as a new candidate population for clinical applications. …”
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PCL scaffold with well-defined hierarchical pores effectively controls cell migration and alignment of human mesenchymal stem cells
Published 2025-04-01“…This highlights the need to design a biopolymeric scaffold with well-defined hierarchical structure and optimized surface properties to improve bone regeneration. …”
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Stem cells in regenerative medicine: Unlocking therapeutic potential through stem cell therapy, 3D bioprinting, gene editing, and drug discovery
Published 2025-06-01“…Stem Cells (SCs) have become potentially instrumental in addressing many human diseases such as cancer, diabetes, age-related diseases and tissue defects. …”
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Therapeutic Potential of Olfactory Ensheathing Cells and Mesenchymal Stem Cells in Spinal Cord Injuries
Published 2017-01-01“…However, treatment options for spinal cord injury are limited, but rehabilitation and experimental technologies have been found to help maintain or improve remaining nerve function in some cases. Mesenchymal stem cells as well as olfactory ensheathing cells seem to show therapeutic impact on damaged spinal cord and might be useful in neuroregeneration. …”
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Evaluation of the Therapeutic Potential of Mesenchymal Stem Cells (MSCs) in Preclinical Models of Autoimmune Diseases
Published 2022-01-01“…This emphasizes a greater need for building robust preclinical models and models that can better predict the clinical translation of stem cell-based therapeutics. Stem cell therapy based on MSCs having the definitive potential to regulate the immune system and control inflammation is emerging as a promising tool for the treatment of autoimmune disorders while promoting tissue regeneration. …”
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Stem cell culture conditions affect in vitro differentiation potential and mouse gastruloid formation.
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Exploring the antioxidant, antiglycation, and anti-inflammatory potential of Oroxylum indicum stem bark extracts.
Published 2025-01-01“…Several extracts from its stem bark were obtained using hexane, ethyl acetate, and ethanol as extraction solvents. …”
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Blood-brain barrier repair: potential and challenges of stem cells and exosomes in stroke treatment
Published 2025-04-01“…This review will present the latest research advances in stem cells and their exosomes in stroke treatment, as well as the challenges of cell source, transplantation timing, dosage, and route of administration in clinical application, aiming to discuss their mechanisms of repairing BBB integrity and potential for clinical application, and proposes future research directions. …”
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