Harnessing mesenchymal stem/stromal cells-based therapies for rheumatoid arthritis: mechanisms, clinical applications, and microenvironmental interactions by Ying-Feng Gao, Na Zhao, Cheng-Hu Hu

“…Abstract Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by persistent joint inflammation and progressive bone destruction. …”
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Exploring aneuploidies in two-center isolated bovine embryonic stem cell lines: Implications for cultured meat production by Chloë Deelkens, Elly De Vlieghere, Mario Van Poucke, Masaki Kinoshita, Jeffrey Aalders, Lieven Thorrez, Bert Devriendt, Ann Van Soom, Luc Peelman, Björn Menten, Catharina De Schauwer, Jolanda van Hengel

“…This research underscores the necessity for systematic monitoring and optimizing culture conditions to mitigate genomic instabilities, ensuring the safe application of bESCs in sustainable food systems. …”
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Early and non-destructive prediction of the differentiation efficiency of human induced pluripotent stem cells using imaging and machine learning by Miki Arai Hojo, Taku Tsuzuki, Yosuke Ozawa, Toshiyuki Araki, Hidetoshi Sakurai

“…Abstract The reproducibility and robustness of many directed differentiation protocols from human induced pluripotent stem cells (hiPSCs) remain low, and the long differentiation induction period significantly limits protocol optimization. …”
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An efficient hybrid Hopfield convolutional neural network for detecting spam bots in Twitter platform by A.V. Santhosh Kumar, N. Suresh Kumar, R. Kanniga Devi

“…This paper proposes a novel spam bot detection system for the Twitter social network that combines profile and tweet-based features. …”
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Design and Testing of a Whole-Row Top-Loosening Stem-Clamping Seedling Extraction Device for Hole Tray Seedlings by Zehui Peng, Fazhan Yang, Yuhuan Li, Xiang Li, Baogang Li, Guoli Xu

“…The pepper plug tray seedlings were selected as the experimental subjects for testing the mechanical properties of the stems. The tensile and compressive mechanical properties of the stems were obtained, and the kinematic model of the seedling spacing process and the mechanical model of the seedling clamping process were established. …”
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In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors. by David Gothard, Emma L Smith, Janos M Kanczler, Cameron R Black, Julia A Wells, Carol A Roberts, Lisa J White, Omar Qutachi, Heather Peto, Hassan Rashidi, Luis Rojo, Molly M Stevens, Alicia J El Haj, Felicity R A J Rose, Kevin M Shakesheff, Richard O C Oreffo

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Human studies of the efficacy and safety of stem cells in the treatment of diabetic peripheral neuropathy: a systematic review and meta-analysis by Seyed Danial Alizadeh, Shima Jahani, Mohammad Rezaei Zadeh Rukerd, Reza Tabrizi, Rasoul Masoomi, Seyedeh Zahra Banihashemian, Mahgol Sadat Hassan Zadeh Tabatabaei, Zahra Ghodsi, Ahmad Pour-Rashidi, James Harrop, Vafa Rahimi-Movaghar

“…Abstract Objective To assess the efficacy and safety of stem cell therapy in human studies for diabetic peripheral neuropathy (DPN). …”
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Protocol for automated graph-based clustering of single-cell RNA-seq data with application in mouse intestinal stem cells by Alexander L.E. Wang, Luca Zanella, Yosuke Ochiai, Leonardo Golinelli, Andrea Califano, Ermanno Malagola, Alessandro Vasciaveo

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Adhesion and proliferation behavior of primary human mesenchymal stem cells on sulfated cellulose nanofiber scaffolds with different sulfate contents by Ritomo Kai, Mayumi Hatakeyama, Shinichiro Iwamoto, Takuya Kitaoka

“…Primary human mesenchymal stem cells (hMSCs) have attracted much attention in regenerative medicine, where stem cell culture currently requires xeno-free (xenogeneic component-free) systems for both media and scaffolds. …”
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Improved genetic algorithm based on rule optimization strategy for fibre allocation by Feng Tan, Zhipeng Yuan, Yong Zhang, Sheng Tang, Feng Guo, Shuai Zhang

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Calibration of Electron Microscopes Through Deep Learning and Bayesian Optimization by Jilles S. van Hulst, Roy A. C. van Zuijlen, Narges Javaheri, Maurits Diephuis, Duarte J. Antunes, W. P. M. H. Heemels

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OPTIMIZATION OF GROWING METHODS OF FOOD OATS IN NORTH STEPPE OF UKRAINE by A. D. Girka, I. A. Kulik

“…It’s been established that optimization of oats mineral nutrition helped to increase stem density on 0,7-6,5% in average. …”
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Planning and optimization models in ready-made concrete production and logistics by Mykhailo Buhaievskyi, Yuri Petrenko

“…The main objectives of this study are as follows: (1) to create a systematic representation of logistics processes in concrete production and distribution; (2) to develop a planning and optimization model for the ready-mix concrete supply chain; (3) to design an infrastructure optimization model for the production and distribution network; (4) to build a simulation model for analyzing production and logistics processes; and (5) to perform experiments to evaluate different system operation modes. …”
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Migrating Birds Optimization for the Seaside Problems at Maritime Container Terminals by Eduardo Lalla-Ruiz, Christopher Expósito-Izquierdo, Jesica de Armas, Belén Melián-Batista, J. Marcos Moreno-Vega

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Pulsed Electromagnetic Field-Assisting Reduced Graphene Oxide-Incorporated Nanofibers for Osteogenic Differentiation of Human Dental Pulp Stem Cells by Juo Lee, Sungmin Lee, Iksong Byun, Myung Chul Lee, Jungsil Kim, Hoon Seonwoo

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Mesenchymal stem cell-derived exosomes–a promising therapeutic approach to improve neurocognitive disorders in chronic obstructive pulmonary disease by Hui Xiao, Xiao Yu, Yushan Liu, Wenhua Jiang, Xiaoting Meng, Zhiyong Dong, Fang Wang

“…Mesenchymal stem cell-derived exosomes (MSC-Exos) are nanoscale extracellular vesicles with unique bioactivity, which have shown great potential in the fields of nervous system diseases, respiratory diseases, bone and joint diseases. …”
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Impact of nitrogen fertilization on soil microbial diversity, its mediated enzyme activities, and stem nematode population in sweet potato fields by Fengyu Shi, Xinpeng Meng, Jiaxin Li, Dan Yang, Jianbin Liu, Xingzhong Liu, Meichun Xiang, Yingbo Zhu

“…The results demonstrated that optimal nitrogen fertilization (64.8 kg ha−1) significantly promoted beneficial microbial populations, enhanced soil urease activity, and reduced the incidence of stem nematode disease while maintaining high sweet potato yields.…”
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Efficient Gene-Editing in Human Pluripotent Stem Cells Through Simplified Assembly of Adeno-Associated Viral (AAV) Donor Templates by Berta de La Cruz, Sanhita Mitra, Bingqing He, Melis Çelik, Debora Kaminski, Erik Smedler, Fredrik Sterky

“…Gene-edited human pluripotent stem cells provide attractive model systems to functionally interrogate the role of specific genetic variants in relevant cell types. …”
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Alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived mesenchymal stem cells by Ying Pan, Li Han, Li Han, Yakun Yang, Xinran Wu, Aijun Wang, Aijun Wang, Aijun Wang, Liangqi Xie, Wuqiang Zhu, Shue Wang, Yuguo Lei, Yuguo Lei

“…BackgroundMesenchymal stem cells (MSCs) hold great promise for treating a variety of human diseases; however, their clinical translation is hindered by challenges in large‐scale expansion while preserving therapeutic potency and maintaining small cell size. …”
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Natural killer cells adopt an activated and decidual-like phenotype after autologous hematopoietic stem cell transplantation in children with cancer by Gabirel Astarloa-Pando, Diego Polanco-Alonso, Víctor Sandá, Ane Orrantia, Ainhoa Amarilla-Irusta, Silvia Pérez-Fernández, Raquel Pérez-Garay, Arrate Sevilla, Ainara Lopez-Pardo, Aritz Tijero, José J. Úriz, Mercedes Rey, Itziar Astigarraga, Bárbara Manzanares-Martin, Aitor Zarandona-Garai, Naiara G. Bediaga, Laura Amo, Olatz Zenarruzabeitia, Francisco Borrego

“…Abstract Background Natural killer (NK) cells are among the first immune cell populations to recover after autologous hematopoietic stem cell transplantation (autoHSCT ), yet their dynamic function in pediatric patients remains understudied. …”
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