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Research progress on the mechanisms of endogenous neural stem cell differentiation in spinal cord injury repair
Published 2025-06-01“…Spinal cord injury (SCI) is a devastating condition with limited self-repair capacity, resulting in long-term disabilities. Endogenous neural stem cells (eNSCs), which are present in the adult central nervous system (CNS), hold significant potential for repairing neural damage following SCI. …”
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82
Effect of the delivery route and dose of multipotent mesenchymal stem cells on the efficacy of cell therapy (review)
Published 2024-07-01“…However, there is generally contradictory evidence on the comparative efficacy of different cell delivery routes. The optimal dose of transplanted cells is also debated, as high MMSC doses may increase the risks of complications and may not have the proper effect both when administered systemically and locally. …”
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83
Synergistic Effects of Natural Products and Mesenchymal Stem Cells in Osteoarthritis Treatment: A Narrative Review
Published 2025-06-01“…Future research should focus on optimizing delivery systems, conducting large-scale randomized controlled trials, and establishing personalized treatment strategies based on patient biomarkers. …”
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84
Simplifying Stem Cell Therapy for IRs: Exploring New Horizons in Interventional Radiology and Cell Therapy
Published 2024-07-01“…By comprehensively understanding the significance of stem cells in interventional radiology, we can implement optimal methodologies to address diverse medical conditions efficiently.…”
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85
Impact of plant density on stem diameter, plant height, and branching in hemp (Cannabis sativa L.)
Published 2025-06-01“…All stem traits were positively correlated with plant height, and stem diameter was the most correlated. …”
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86
Advancing Osteoarthritis Treatment: The Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes and Biomaterial Integration
Published 2024-10-01“…Future directions should focus on optimizing delivery systems, exploring personalized medicine approaches, and conducting comparative effectiveness studies to fully realize the potential of exosome therapies for OA treatment. …”
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87
Design and Experimental Validation of Stem-Clamping-and-Pull-Out-Type Pepper Plug Seedling-Picking Mechanism
Published 2025-07-01“…To develop a highly efficient, stable, and minimally damaging seedling-picking mechanism, this study proposed a design scheme for a stem-clamping-and-pulling-out-type seedling-picking end actuator driven by a non-circular gear system. …”
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88
Tracking adipose-derived mesenchymal stromal cells in the eye: Integrating IVIS imaging and Alu PCR for enhanced detection of human cells
Published 2025-12-01“…Introduction: Cell transplantation finds broad applications in medical science, with applications ranging from stem cell therapies to cancer research. Despite its widespread use, inherent risks such as tumor formation and immune rejection necessitate a comprehensive understanding of transplanted cell dynamics. …”
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89
Jawbone mesenchymal stromal cells attenuate acute inflammation via hematopoietic niche reinforcement
Published 2025-08-01“…BackgroundThe bone marrow microenvironment, comprising various cell types and molecular signals, finely orchestrates the self‐renewal and lineage commitment of hematopoietic stem cells (HSCs). Although most investigations have centered on mesenchymal stem cells (MSCs) from long bones, the distinct properties and immunoregulatory functions of craniofacial bone marrow derived MSCs remain largely unexplored. …”
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90
In Vivo Healing of Meniscal Lacerations Using Bone Marrow-Derived Mesenchymal Stem Cells and Fibrin Glue
Published 2012-01-01“…An experimental model for optimizing various permutations of this delivery system in vivo was tested in this study. …”
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91
Adipose-derived stem cells and antibiotics: A novel synergistic approach for treating implant-related osteomyelitis
Published 2024-05-01“…This article focused on exploring the potential of combination therapy with adipose-derived stem cells (ADSCs) and antibiotics to overcome these challenges, thereby enhancing treatment efficacy. …”
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92
Successful dupilumab treatment in a patient with severe dermatitis following allogenic hematopoietic stem cell transplantation
Published 2025-04-01“…Abstract Background Allogenic hematopoietic stem cell transplantation (HSCT) is the optimal treatment of hematologic diseases and various malignancies. …”
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Efficacy and safety of stem cells in the treatment of glaucoma: systematic review and meta-analysis based on animal experiments
Published 2025-07-01“…None of these studies reported any adverse systemic events.ConclusionThis meta-analysis provides preclinical evidence supporting stem cell transplantation as a multimodal therapeutic strategy for glaucoma, demonstrating significant efficacy in IOP modulation, neurostructural preservation, and neurotrophic factor expression. …”
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95
A Systematic Review of Mesenchymal Stem Cell-Derived Extracellular Vesicles: A Potential Treatment for Glioblastoma
Published 2024-10-01“…Recent research has highlighted the potential of extracellular vesicles (MSC-EVs) produced from mesenchymal stem cells as a potential treatment approach for GBM. …”
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96
Micromagnetic simulation and optimization of spin-wave transducers
Published 2025-06-01“…Abstract The increasing demand for higher data volume and faster transmission in modern wireless telecommunication systems has elevated requirements for 5G high-band RF hardware. …”
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Mathematical Modeling of Organizational Project Management
Published 2025-12-01“…The relevance of the study stems from the growing complexity of projects and the need to develop tools to minimize risks and optimize resources. …”
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Route of Application and Dose Evaluation of Dental Pulp Stem Cells for the Treatment of Sialadenitis Caused by Sjögren’s Syndrome: A Preclinical Study
Published 2025-04-01“…<b>Background:</b> Sjögren’s syndrome (SS) is an autoimmune disorder characterized by sicca syndrome and/or systemic manifestations. In this study, non-obese diabetic (<i>NOD</i>) mice were used as an animal model for studying SS, to evaluate the optimal administration route and dose range of dental pulp stem cells (DPSCs) in the treatment of sialadenitis caused by SS. …”
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Assessment of mesenchymal stem cells for the treatment of spinal cord injury: a systematic review and network meta-analysis
Published 2025-04-01“…ObjectiveThis study aims to explore the clinical efficacy of mesenchymal stem cell (MSC) transplantation in the treatment of patients with spinal cord injury (SCI) through a network meta-analysis and to discuss the optimal transplantation strategy for treatment.MethodsWe conducted a computer search of clinical randomized controlled studies on MSC treatment for SCI in databases including PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Journal Database (VIP), Wanfang Database, and Chinese Biomedical Literature Service System (SinoMed) up to March 2024. …”
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