CHALLENGES OF MODERNITY IN RUSSIAN EDUCATION: ANALYSIS AND STRATEGIES by Elena F. Moros

“…This means that the education system must promptly identify real and potential hazards, analyze them in detail, and subsequently develop effective tools for risk mitigation and the optimization of further safe development of the educational environment. …”
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Beyond insulin: advancing frontiers in cell-based and genetic therapies for type 1 diabetes management by Tamer A. Addissouky

“…Furthermore, advances in glucose-responsive “smart” insulins, ultra-rapid-acting formulations, and automated delivery systems are optimizing glycemic control. Emerging fields such as nanotechnology, bioartificial pancreas development, and microbiome modulation further expand the T1D therapeutic landscape. …”
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Performance Analysis of IRS-Assisted Multi-Link FSO System Under Pointing Errors by Takumi Ishida, Chedlia Ben Naila, Hiraku Okada, Masaaki Katayama

“…This work aims to evaluate the improvement of the system performance achieved through optimized IRS positioning while accounting for the main degrading factors inherent in FSO systems and IRS design. …”
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Trace-level analysis of geosmin in aquaculture systems by Headspace SPME-GC-MS/MS by Shi-Zhan Tang, Zhong-Xiang Chen, Li Huang, Chen-Hui Li, Ning-Ning Du, Jing Ren, Dong-Li Qin, Peng Wang

“…The persistent challenge of earthy off-flavors in aquatic systems stems largely from geosmin (GSM), a microbial metabolite with an exceptionally low human detection threshold. …”
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The Effects of Land Use Mix on Urban Vitality: A Systemic Conceptualization and Mechanistic Exploration by Yuefei Zhuo, Hangang Hu, Guan Li

“…Key findings include the following: (1) LUM significantly enhances urban vitality, acting as a crucial urban system configuration for both daytime and nighttime activity. (2) The efficacy of LUM stems more from systemic interconnections—convenient access to adjacent spaces (proximity) and functional coordination among diverse land uses—than mere compositional diversity, emphasizing the importance of interrelated elements within the urban fabric. (3) The system’s response to LUM exhibits significant spatial and temporal heterogeneity; proximity’s impact is most variable, while diversity and coordination effects are more stable, underscoring the dynamic and context-dependent nature of these interactions. (4) System-adaptive strategies are crucial: newly developed urban areas benefit from foundational infrastructure and land use diversity (system inputs), while revitalizing older towns requires optimizing spatial accessibility and functional coordination (enhancing existing system linkages). …”
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Orbital Analysis of a Dual Asteroid System Explorer Based on the Finite Element Method by Linli Su, Wenyu Feng, Lie Yang, Zichen Fan, Mingying Huo, Naiming Qi

“…This inadequacy primarily stems from the non-tidally locked nature of asteroid systems, which necessitates continual adjustments to account for changes in gravitational fields. …”
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Next-Generation Vaccine Platforms: Integrating Synthetic Biology, Nanotechnology, and Systems Immunology for Improved Immunogenicity by Majid Eslami, Bahram Fadaee Dowlat, Shayan Yaghmayee, Anoosha Habibian, Saeedeh Keshavarzi, Valentyn Oksenych, Ramtin Naderian

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Optimized nitrogen fertilizer management enhances soybean (Glycine max (L.) Merril.) yield and nitrogen use efficiency by promoting symbiotic nitrogen fixation capacity by Yaxin Xu, Quantong Gao, Lihua Xue, Jianxin Zhang, Cong Wang

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Deep Reinforcement Learning-Enabled Computation Offloading: A Novel Framework to Energy Optimization and Security-Aware in Vehicular Edge-Cloud Computing Networks by Waleed Almuseelem

“…Moreover, ensuring data security and optimizing energy usage within this framework remain significant challenges. …”
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Enhanced Spectral Efficiency in RIS-Assisted MIMO Systems Through Joint Precoding and RIS Configuration by Mohammed Adil Abbas, Aqiel N. Almamori, Ahmed Jumaa Lafta, Asaad H. Sahar

“…This paper proposes a unified joint optimization framework to enhance spectral efficiency in reconfigurable intelligent surface (RIS)-assisted multiple-input multiple-output (MIMO) systems. …”
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Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids by Cong-Yi Shen, Qi-Rong Zhou, Xiang Wu, Xin-Yu Han, Qin Zhang, Xiao Chen, Yu-Xiao Lai, Long Bai, Ying-Ying Jing, Jian-Hua Wang, Cheng-Long Wang, Zhen Geng, Jia-Can Su

“…Methods This study employed a digital light processing system to perform 3D bioprinting of a DNA-silk fibroin (DNA-SF) hydrogel sustained-release system (DSRGT) with bone-marrow mesenchymal stem cells (BMSCs) to construct millimeter-scale cerebral organoids. …”
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Advancing gene editing therapeutics: Clinical trials and innovative delivery systems across diverse diseases by Mozhghan Raigani, Zohre Eftekhari, Ahmad Adeli, Fatemeh Kazemi-Lomedasht

“…At the same time, viral vectors have been used for ex vivo modification of T cells and hematopoietic stem cells in autoimmune and infectious diseases. …”
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Microbiome Modulation in Pediatric Leukemia: Impact on Graft-Versus-Host Disease and Treatment Outcomes: A Narrative Review by Samuel Bogdan Todor, Cristian Ichim

“…The gut microbiome significantly influences the outcomes of pediatric leukemia, particularly in patients undergoing hematopoietic stem cell transplantation (HSCT). Dysbiosis, caused by chemotherapy, antibiotics, and immune system changes, contributes to complications such as graft-versus-host disease (GVHD), gastrointestinal issues, and infections. …”
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Establishment of a Highly Efficient In Vitro Regeneration System for <i>Nandina domestica</i> ‘Firepower’ by Xin Zhao, Hao Dong, Yanhua Li, Xinxin Zhang, Yajing Ning, Chengpeng Cui, Shujuan Li

“…After a two-day hardening period for tissue-cultured plantlets, a substrate consisting of peat soil, vermiculite, and perlite at a ratio of 2:2:1 was determined to be the optimal cultivation formulation. This system provides a framework for the industrialized production of <i>Nandina domestica</i> ‘Firepower’.…”
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Selective modulation of the bone remodeling regulatory system through orthodontic tooth movement—a review by Jan Christian Danz, Martin Degen

“…The ensuing sclerostin-depleted region may enhance stem cell differentiation into osteoblasts and subperiosteal osteoid formation. …”
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Application of non-contact infrared monitoring technology in marine controlled-source electromagnetic transmission systems by C. Wang, M. Deng, Z. Ren, M. Wang

“…However, the high-power operation of these systems poses significant safety challenges, mainly stemming from undetectable thermal anomalies. …”
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Matrix vesicle-inspired delivery system based on nanofibrous chitosan microspheres for enhanced bone regeneration by Haolin Bian, Fangfang Song, Shilei Wang, Wei Sun, Bo Hu, Xichao Liang, Hongye Yang, Cui Huang

“…Additionally, the nanofibrous network of NCMP mimics the architecture of natural extracellular matrix (ECM), creating an optimal niche for the active adhesion of stem cells to its surface, exhibiting good biocompatibility, immunoregulation, and osteogenic performance. …”
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Global research trends in biomarkers, therapeutic targets, and drugs for amyotrophic lateral sclerosis: a bibliometric and visualization analysis by Na Guo, Weicheng Huang, Weicheng Huang, Jianliang Huang, Jianliang Huang, Jianliang Huang, Ying Liu, Kai Zhu, Wei Gao, Wei Gao, Wei Gao

“…Future directions should prioritize biomarker standardization, optimization of drug delivery systems, and Clinical Translation.…”
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Efficient induction of tetraploids via adventitious bud regeneration and subsequent phenotypic variation in Acacia melanoxylon by Shenxiu Jiang, Yufei Xia, Aoyu Ling, Jianghai Shu, Kairan You, Shun Wang, Dingju Zhan, Bingshan Zeng, Jun Yang, Xiangyang Kang

“…Results In this study, using the superior A. melanoxylon clone SR3, an in vitro regeneration system using a bud-bearing stem segment was established. …”
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A tunable human intestinal organoid system achieves controlled balance between self-renewal and differentiation by Li Yang, Xulei Wang, Xingyu Zhou, Hongyu Chen, Sentao Song, Liling Deng, Yao Yao, Xiaolei Yin

“…This optimization facilitates the scalability and utility of the organoid system in high-throughput applications.…”
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