Scopoletin and Scoparone from Viola philippica Attenuate the Virulence of Pseudomonas aeruginosa by Inhibiting Quorum Sensing-Related Genes by Luo Y, Zhang S, Ou S, Shen C, Xiao Q, Chen W, Pu J, Zeng J, Zheng D, Huang B, Chen C

“…Plant-based natural products are rich sources of anti-QS compounds. Viola philippica Cav. …”
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Non-Invasive Ventilation Failure in Pediatric ICU: A Machine Learning Driven Prediction by Maria Vittoria Chiaruttini, Giulia Lorenzoni, Marco Daverio, Luca Marchetto, Francesca Izzo, Giovanna Chidini, Enzo Picconi, Claudio Nettuno, Elisa Zanonato, Raffaella Sagredini, Emanuele Rossetti, Maria Cristina Mondardini, Corrado Cecchetti, Pasquale Vitale, Nicola Alaimo, Denise Colosimo, Francesco Sacco, Giulia Genoni, Daniela Perrotta, Camilla Micalizzi, Silvia Moggia, Giosuè Chisari, Immacolata Rulli, Andrea Wolfler, Angela Amigoni, Dario Gregori

“…This study aims to identify predictors of first-attempt NIV failure in PICU patients by testing various machine learning techniques and comparing their predictive abilities. <b>Methods</b>: Data were sourced from the TIPNet registry, which comprised patients admitted to 23 Italian Paediatric Intensive Care Units (PICUs). …”
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Chemicals of concern in select packaged hair relaxers available on the Kenyan market: an examination of ingredient labels and measurement of pH by Beatrice N. Irungu, Adana A. M. Llanos, Adana A. M. Llanos, Adana A. M. Llanos, Mary Nyangi, Teresa Olisa, Esther Matu, Esther Matu, Amber Rockson, Alexis Schaefer, Adiba Ashrafi, Mary Beth Terry, Mary Beth Terry, Jasmine A. McDonald, Jasmine A. McDonald, Janet Nudelman, Laura Dobbs Gillan, Pujeeta Chowdhary, Sabina Wachira, Cecilia Kimani

“…BackgroundThere is an emerging interest in the investigation of hair relaxers as important sources of exposure to chemicals of concern (CoCs) and their associated adverse health effects. …”
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Integrated single-cell analysis reveals the regulatory network of disulfidptosis-related lncRNAs in bladder cancer: constructing a prognostic model and predicting treatment respons... by Jiafu Xiao, Jiafu Xiao, Jiafu Xiao, Wuhao Liu, Wuhao Liu, Wuhao Liu, Jianxin Gong, Jianxin Gong, Jianxin Gong, Weifeng Lai, Weifeng Lai, Weifeng Lai, Neng Luo, Neng Luo, Neng Luo, Yingfan He, Junrong Zou, Junrong Zou, Zhihua He, Zhihua He, Zhihua He

“…This study aims to investigate disulfidptosis-related lncRNAs (DRLs) as potential prognostic markers for BLCA patients.MethodsUtilizing single-cell sequencing data, RNA sequencing data, and corresponding clinical information sourced from the GEO and TCGA databases, this study conducted cell annotation and intercellular communication analyses to identify differentially expressed disulfide death-related genes (DRGs). …”
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Development and validation of an interpretable multi-task model to predict outcomes in patients with rhabdomyolysis: a multicenter retrospective cohort studyResearch in context by Chunli Liu, Jie Shi, Fengjuan Wang, Duo Li, Yu Luo, Bofan Yang, Yunlong Zhao, Li Zhang, Dingwei Yang, Heng Jin, Jie Song, Xiaoqin Guo, Haojun Fan, Qi Lv

“…We aimed to develop and externally validate an interpretable multi-task machine learning (ML) model to predict four clinical outcomes in patients with rhabdomyolysis: AKI, disease severity, the need for RRT, and in-hospital mortality. Methods: We conducted a retrospective study using three data sources: the eICU Collaborative Research Database (eICU-CRD), the Medical Information Mart for Intensive Care IV (MIMIC-IV), and electronic medical records from four tertiary hospitals in China. …”
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Systematic review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP): study protocol by Stuart B Hooper, Peter G Davis, Anup C Katheria, Venkataseshan Sundaram, Lisa Askie, Martin Kluckow, Shigeharu Hosono, Eugene Dempsey, Walid El-Naggar, William Tarnow-Mordi, Heike Rabe, Ronny Knol, Lelia Duley, Thomas Debray, Amir Kugelman, Kellie Murphy, Anna Lene Seidler, Kylie E Hunter, Michael Meyer, Catalina De Paco Matallana, John Kattwinkel, Judith Mercer, Justin Josephsen, Karen Fairchild, Ola Andersson, Vikram Datta, Graeme Polglase, Angie Barba, John Simes, Ava Grace Tan-Koay, Anu George, Anu Sachdeva, Arjan Te Pas, Ashish K C, Bimlesh Kumar, Carl Backes, Chamnan Tanprasertkul, Chayatat Ruangkit, G Ram Mohan, Gillian Gyte, Guillermo Carroli, Heidi Al-Wassia, Hytham Atia, Islam Nour, Jiangqin Liu, John Bauer, Kristy Robledo, Lakhbir Dhaliwal, Laura Perretta, Lin Ling, Manoj Varanattu, Maria Goya, Musa Silahli, Neelam Kler, Neil Finer, Omar Kamlin, Peter Giannone, Pharuhad Pongmee, Prisana Panichkul, Sandeep Kadam, Sangkae Chamnanvanakij, Shiraz Badurdeen, Simone Pratesi, Thomas Ranjit, Victor Lago Leal, Waldemar Carlo

“…Network meta-analysis (NMA) enables comparison and ranking of all available interventions using a combination of direct and indirect comparisons.Objectives (1) To evaluate the effectiveness of cord management strategies for preterm infants on neonatal mortality and morbidity overall and for different participant characteristics using IPD meta-analysis. (2) To evaluate and rank the effect of different cord management strategies for preterm births on mortality and other key outcomes using NMA.Methods and analysis Systematic searches of Medline, Embase, clinical trial registries, and other sources for all ongoing and completed randomised controlled trials comparing cord management strategies at preterm birth (before 37 weeks’ gestation) have been completed up to 13 February 2019, but will be updated regularly to include additional trials. …”
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The global prevalence of biofilm-forming Enterococcus faecalis in clinical isolates: a systematic review and meta-analysis by Ephrem Tamrat, Zelalem Asmare, Alene Geteneh, Assefa Sisay, Ermias Getachew, Brhanu Kassanew, Mesfin Dessale, Yalewayker Gashaw, Abdu Jemal, Muluken Gashaw, Alembante Bazezew, Solomon Gedfie, Woldeteklehaymanot Kassahun, Wagaw Abebe, Zelalem Dejazmach, Tadesse Misganaw, Agenagnew Ashagre, Marye Nigatie, Abebe Adisu Damtie, Bewuketu Belete Alemu, Zewdu Tefera, Bahriew Mezgebu, Getinet Kumie, Mulugeta Kiros, Melese Abate Reta

“…Publication bias was evaluated using Egger’s test and corrected with trim-and-fill analysis. …”
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Effects of olympic combat sports on physical fitness in non-athlete students: a systematic review with meta-analysis by Jordan Hernandez-Martinez, Jordan Hernandez-Martinez, Izham Cid-Calfucura, Eduardo Guzmán-Muñoz, Eduardo Guzmán-Muñoz, Tomas Herrera-Valenzuela, Pedro Delgado-Floody, Cristian Nuñez-Espinosa, Cristian Nuñez-Espinosa, Cristian Nuñez-Espinosa, Braulio Magnani Branco, Jorge Mota, Hadi Nobari, Joaquin Perez-Carcamo, Edgar Vásquez-Carrasco, Edgar Vásquez-Carrasco, Pablo Valdés-Badilla, Pablo Valdés-Badilla

“…This systematic review and meta-analysis aimed to evaluate the effects of OCS interventions on selected physical fitness outcomes among school-aged and university students, compared with active or standard.MethodsA systematic literature search was conducted in May 2024 and April 2025 using seven generic databases—PubMed, ProQuest, EBSCOhost, CINAHL Complete, Scopus, Web of Science (core collection), and PEDro (Physiotherapy Evidence Database). …”
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Preoperative and intraoperative neuromonitoring and mapping techniques impact oncological and functional outcomes in supratentorial function-eloquent brain tumours: a systematic re... by Asfand Baig Mirza, Amisha Vastani, Rishabh Suvarna, Sami Rashed, Aws Al-Omari, Engelbert Mthunzi, Feras Fayez, Nicala Rampersad, Josephine Jung, Alba Díaz Baamonde, José Siado Mosquera, Ali Elhag, Francesco Marchi, Richard Gullan, Keyoumars Ashkan, Ranjeev Bhangoo, Francesco Vergani, Ana Mirallave-Pescador, José Pedro Lavrador

“…Methods: This systematic review and meta-analysis examined literature up to March 2023, sourced from PubMed, Embase, and Medline. …”
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Rapid, sensitive, and species-independent detection of Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 antibodiesResearch in context by Elif Karaaslan, Cheng-Feng Chiang, Gülter Öncü Kurutaş, Orçun Barkay, Nesibe Selma Çetin Güler, Merve Yazıcı Kalkan, Hanife Nur Karakoç Parlayan, Özlem Akdoğan, Aysel Kocagül Çelikbaş, Firdevs Aksoy, Umut Devrim Binay, Nurcan Baykam, Gürdal Yılmaz, Mohammad M. Sajadi, Scott D. Pegan, John D. Klena, Joel M. Montgomery, Faruk Karakeçili, Ahmet Kalkan, Mehmet Ziya Doymaz, Christina F. Spiropoulou, Éric Bergeron

“…National Institute of Allergy and Infectious Diseases (1R01AI180125-01A1): sample acquisition. Funding sources did not have a role in the writing or decision to submit the publication.…”
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The Effect of L-glutathione Postharvest Treatment on the Physicochemical Characteristics of Sabrina Strawberry Fruit during Cold Storage by Karim Mandahakki, Hamid Hassanpour

“…., 2023).Materials and MethodsSabrina strawberry fruit was obtained from a commercial greenhouse located in Urmia in the full maturity stage. …”
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Subtype cluster analysis unveiled the correlation between m6A- and cuproptosis-related lncRNAs and the prognosis, immune microenvironment, and treatment sensitivity of esophageal c... by Ming Zhang, Yani Su, Pengfei Wen, Xiaolong Shao, Peng Yang, Peng An, Wensen Jing, Lin Liu, Zhi Yang, Mingyi Yang

“…Data on 23 m6A regulators and 25 cuproptosis-related genes were sourced from the latest literature. The m6aCRLncs linked to EC were identified through co-expression analysis. …”
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Genetic Diversity and Relationship Analysis of Different Local and International Cultivars and some Strawberry Clones (Fragaria× ananassa Duch) by Masume Abedi, Mehdi Hadadinejad, Kamran Ghasemi, Ghafar Kiani

“…Transplants of imported cultivars were sourced from the Kurdistan Agricultural and Natural Resources Research Center. …”
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CONSORT 2025声明：随机试验报告指南更新版 CONSORT 2025 Statement: Updated Guideline for Reporting Randomised Trials by 译者：李辉1，2，谢雪微1，3 (Translator: LI Hui1,2, XIE Xuewei1,3 )

“…Conclusions Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomised trials to ensure that trial reports are clear and transparent.…”
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Enhancing the Accuracy of Land Use/Cover Map Using Some Spectral Indices in Sarab County–East Azerbaijan by A. Sarabchi, H. Rezaei, F. Shahbazi

“…Materials and Methods As an initial step, LULC features were identified through fieldwork, and their geographic coordinates were recorded using GPS. …”
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Analyzing Political Distrust as a Driving Factor for Protesting Political Actions in the Context of Security Threats and Political Corruption by Mahmoudreza Rahbarqazi, Morteza Ebrahimi

“…The dataset was sourced from the seventh wave of the World Values Survey, which utilized a stratified sampling technique targeting Iranian citizens. …”
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Genetic diversity analysis and core collection construction of Phyllanthus emblica based on SSR markers by WANG Jianchao, ZHANG Xiaoyan, ZHANG Lijie, LI Tao, XIE Lixue

“…The SM genetic distance, Jaccard genetic distance, and Nei & Li genetic distance were used to select the appropriate clustering method. The priority sampling strategy and random sampling strategy were evaluated. …”
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Long-term exposure to outdoor fine particulate and physical activity with mortality and cardiovascular events: an analysis of the Prospective Urban Rural Epidemiology (PURE)-China... by Jun Hao, Zhiguang Liu, Bo Hu, Duolao Wang, Sumathy Rangarajan, Yang Wang, Chuangshi Wang, Lap Ah Tse, Weida Liu, Sidong Li, Minghai Yan, Qiujing Cai, Salim Yusuf, Wei Li

“…This study aims to explore these interactions related to CVD and mortality. Methods: We analysed data from the PURE-China cohort, including 39,970 adults aged 35–70 years, with a median follow-up of 11.9 years. …”
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Editorial by Bulent Cavas

“…The study finds that digital sources, particularly the internet, play a dominant role in shaping sexual awareness. …”
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Invasive pneumococcal disease in Argentina: a snapshot from a retrospective observational study on serotypes, antimicrobial resistance, and the potential impact of the COVID-19 pan... by Jonathan Zintgraff, Paula Gagetti, Nahuel Sánchez Eluchans, Paulina Marchetti, María Alicia Moscoloni, Lucia Irazu, Claudia S. Lara, Alejandra Corso, Claudia Hernández, Alejandra Blanco, Vanessa Reitjman, Carlos Vay, Claudia Alfonso, Claudia Garbaz, Claudia Etcheves, Flavia Amalfa, Debora Stepanik, Liliana Fernandez Caniggia, Marisa Turco, Adriana Procopio, Miryam Vazquez, Mariela Soledad Zarate, Marta Giovanakis, Marta Flaibani, Nora Gómez, Rosana Pereda, Liliana Guelfand, Silvana Manganello, Iliana Martinez, Ana Togneri, Andrea Pacha, Maria L. Benvenutti, Mabel Rizzo, Silvia Beatriz Fernandez, Maria Cervelli, Mónica Machain, Andrea Fascente, Laura Paniccia, María Adelaida Rosetti, Hebe Gullo, Maria Susana Commisso, Nory Cerda, Carolina Vaccino, Victoria Monzani, Laura Morvay, Micaela Sogga, Viviana Vilches, Ana Laura Mariñazky, Appendino Andrea, Laura Biglieri, Sandra Bognanni, Cecilia Vescina, Johanna Pérez, Liliana Meccia, Marisa Almuzara, Alejandra Sale, Mónica Sparo, Sofía Murzicato, Gabriela Galán, Roxana Depardo, Maricel Garrone, Adriana Fernández Laussi, Graciela Priore, Mónica Vallejo, Cecilia Barrachia, Adriana Melo, Victoria Ascua, Patricia Lopez, Daniela Carrizo, Patricia Valdez, Mariela Silvia Farfan, Viviana David, Leyla Guadalupe Gómez Capara, Mónica Graciela Sucin, Viviana Isabel Saito, Laura Pícoli, Mariana Carol Rey, Isabel Ana Marques, Norma Ester Cech, Susana Ortiz, Mario FloresTeresa M Strella, Omar Daher, Ana Littvik, Claudia Amareto De Costabella, Lidia Wolff De Jakob, Lilia Norma Camisassa, Liliana González, Patricia Montanaro, Marina Botiglieri, Paulo Cortéz, Ana María Pato, Juan Pellegrini, Lorena del Barco, María Eugenia de Torres, María Silvia Díaz, María Ofelia Moulins, Luis Otaegui, Norma Yoya, Nancy Comello, Silvana Vivaldo, Nancy Noemí Pereyra, Marcelo Tóffoli, Gabriela Granados, Beatriz Resina, Adriana Pereyra, Gladys Almada, Sonia Flores, Mónica Romanazi, Ada Zanusso, Adriana Edith Acosta, Alfredo Matile, Beatriz Garcia, Lorena Leguizamón, Viviana Villalba, Cristina Pérez, Fernanda Bulgueroni, Néstor Blazquez, María Laura Álvarez, Cristina Carranza, Mariela Roncallo, Gonzalo Crombas, Daniela Durani, Graciela Stafforini, Maria Gabriela Rivolier, Cristina Bono, Eloisa Aguirre, Ana Berejnoi, Silvia Amador, Norma Sponton, Hugo Castro, Marisa López, Ema María Fernández, Hugo Rigo, Josefina Villegas, Vilma Krause, Alejandra Vargas, Mariel Borda, Andrea Badano, Adriana Ernst, Andrea Nepote, Maria Gilli, Emilce Mendez, Alicia Nagel, Maria Inés Zamboni, Noemi Borda, Stella Virgolini, Maria Rosa Baroni, Marciana Cragnolino, Maria Elisa Pavón, Manuel Boutureira, Marcela Vargas, Alejandra Guerra, Ana Maria Villagra De Trejo, José Assa, Fernández de Gandur, Norma Cudmani

“…This study aimed to characterise changes in serotype distribution, in vitro antimicrobial susceptibility, and the frequency of invasive pneumococcal disease (IPD) in paediatric and adult populations in Argentina during the pre-COVID (2018–2019) and post-COVID (2021–2022) eras. Methods: We conducted a national laboratory-based surveillance study analysing 1304 S. pneumoniae isolates sourced from Argentina's National Surveillance Program for invasive pneumococcal disease. …”
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