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7921
Palliative care burden and specialist service utilisation for individuals with cardiovascular disease in Australia: a national population-based observational study
Published 2025-05-01“…In advanced stages, patients with CVD often require palliative care due to reduced health-related quality of life from physical, psychological and spiritual symptoms, along with physical disability.Objectives To investigate (1) the symptom and function burden of patients with CVD on their first admission to specialist palliative care services and (2) how these care burdens, and other clinical characteristics, affected patients’ utilisation of community-based versus inpatient services.Design A national population-based observational study using point-of-care outcomes sourced from the Australian palliative care outcomes and collaboration (PCOC).Settings Community-based and inpatient Specialist palliative care services across Australia registered in the PCOC.Participants Patients who required specialist palliative care principally for CVD, and whose death occurred between 1 January 2013 and 31 December 2022.Methods Five validated clinical instruments were used to collect point-of-care outcomes on each individual’s function (Resource Utilisation Groups - Activities of Daily Living (RUG) & Australia-modified Karnofsky Performance Status (AKPS)), symptom distress (Symptoms Assessment Scale & Palliative Care Problem Severity Score) and other clinical characteristics (Palliative Care Phases). …”
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7922
Effectiveness of a Web-Based Medication Education Course on Pregnant Women’s Medication Information Literacy and Decision Self-Efficacy: Randomized Controlled Trial
Published 2025-01-01“…The identification of appropriate medication information sources requires adequate medical information literacy (MIL). …”
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7923
Construction of enhanced MRI-based radiomics models using machine learning algorithms for non-invasive prediction of IL7R expression in high-grade gliomas and its prognostic value...
Published 2025-03-01“…To evaluate prognosis, we applied both univariate and multivariate Cox regression analyses alongside Kaplan–Meier survival analysis. …”
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7924
Efficacy and safety of stem cells in the treatment of glaucoma: systematic review and meta-analysis based on animal experiments
Published 2025-07-01“…Accordingly, this systematic review and meta-analysis evaluated the therapeutic efficacy and safety of stem cell transplantation in experimental glaucoma models, with a focus on functional outcomes (IOP modulation), structural preservation (RGC survival, and nerve fiber layer integrity), and neuroprotective efficacy.MethodsA systematic literature retrieval from multiple online databases (e.g., PubMed, Web of Science, Embase, Cochrane Library, Scopus, CNKI, WFSD, VIP, and CBM) was conducted through 3 January 2025, to identify relevant animal experimental studies. …”
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7925
Identifying Shahid Sattari’s Strategic Leadership Competencies: Teachings for Public Managers
Published 2025-03-01“…To ensure reliability, the two-coder agreement method was employed to evaluate and confirm findings. …”
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7926
Sarcopenia in type 2 Diabetes mellitus among Asian populations: prevalence and risk factors based on AWGS- 2019: a systematic review and meta-analysis
Published 2025-04-01“…The present review aimed to evaluate the prevalence of sarcopenia among Asian T2DM patients and identify associated risk factors using AWGS-2019 criteria through systematic review and meta-analysis. …”
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7927
Effectiveness of general practitioner-delivered nutrition care on dietary and health outcomes in adults with chronic conditions: a systematic review
Published 2025-08-01“…Objectives To evaluate the effectiveness of nutrition care delivered by general practitioners (GPs) compared with usual or no care on dietary and health outcomes in adults with diet-related chronic conditions or risk states and to examine which intervention components are associated with effectiveness.Study design A systematic review of randomised controlled trials (RCTs).Data sources CINAHL, Embase, MEDLINE and ProQuest Nursing and Allied Health databases were searched in October 2021 and updated in February 2024 for articles related to GPs, nutrition care and diet-related health outcomes.Eligibility criteria Published RCTs were included according to the following criteria: adults with or at risk of diet-related chronic conditions; nutrition care delivered by GPs in the primary care setting; usual or no care as comparators; and dietary and/or health outcomes with a minimum 3-month follow-up. …”
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7928
A Review of Degradation and Reliability Analysis of a Solar PV Module
Published 2024-01-01“…Also, as the world’s energy portfolio evolves toward cleaner energy sources, PV deployment is anticipated to maintain this increasing trend. …”
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7929
A case-crossover study on association between ambient temperature and injury incidence in Shenzhen City
Published 2025-05-01“…The meteorological data were sourced from the fifth generation of the European Centre for Medium-Range Weather Forecasts (ECMWF) land reanalysis data. …”
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7930
A Feasibility Study for Clinical Implementation of hypo fractionated SBRT Program at a Clinic in an LMIC Using Locally Designed Lung Phantom
Published 2025-06-01“…The goal is to alleviate the burden on patients and health care providers, particularly in the context of limited resources. Methods and Materials: A lung phantom was designed from locally sourced materials consisting of wood slabs to mimic the lung, a perspex tank filled with water for tissue equivalence, and a 3-cm diameter acrylic ball to simulate the tumor. …”
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7931
Semaglutide in MASLD Patients: Improved Survival and Liver Outcomes
Published 2025-07-01“…These benefits appear to result primarily from metabolic improvements and anti-inflammatory effects. <b>Materials and Methods</b>: Data were sourced from TriNetX, a global health research platform with de-identified electronic medical records spanning 135 million patients across 112 healthcare organizations worldwide. …”
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7932
Paeonia suffruticosa Andrews root extract ameliorates photoaging via regulating IRS1/PI3K/FOXO pathway
Published 2025-03-01“…However, there are few reports on the photoprotective effects of P. suffruticosa Andr. root bark, this study aims to investigate its research in this area.MethodsThis study utilized P. suffruticosa Andr. root bark sourced from Kunming, Yunnan Province, China. …”
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7933
Bridging Data Silos in Oncology with Modular Software for Federated Analysis on Fast Healthcare Interoperability Resources: Multisite Implementation Study
Published 2025-04-01“… BackgroundReal-world data (RWD) from sources like administrative claims, electronic health records, and cancer registries offer insights into patient populations beyond the tightly regulated environment of randomized controlled trials. …”
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7934
Fucoidan alleviates high sucrose-induced metabolic disorders and enhances intestinal homeostasis through modulation of Notch signaling
Published 2025-05-01“…Introduction: The therapeutic potential of fucoidan (FUC), a natural polysaccharide, in metabolic disorders is recognized, yet its underlying mechanisms remain unclear. Methods: We conducted investigations into the therapeutic mechanisms of FUC sourced from Sargassum fulvellum concerning metabolic disorders induced by a high-sucrose diet (HSD), employing Drosophila melanogaster and mice models. …”
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7935
Eradication of Helicobacter pylori for prevention of aspirin-associated peptic ulcer bleeding in adults over 65 years: the HEAT RCT
Published 2025-08-01“…All plausible events which mentioned GI bleeding or peptic ulcer in any of the outcome data sources were evaluated by a blinded adjudication committee comprising three specialist clinicians. …”
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7936
Investigating Engine Performance and Emission Characteristics during Testing of Diesel-Biodiesel Mixed Fuels Obtained from Vegetable Oils and their Modeling
Published 2025-06-01“…A total of 36 treatments were evaluated using a randomized complete block design (RCBD), incorporating four engine speeds and nine fuel types. …”
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7937
Effect of anti-inflammatory diets on health-related quality of life in adults with chronic disease: a systematic review and meta-analysis
“…Objective To evaluate the effectiveness of anti-inflammatory diets on health-related quality of life (HRQOL) in adults with at least one chronic disease.Design Systematic review and meta-analysis of randomised controlled trials (RCTs).Data sources MEDLINE, EMBASE, CINAHL, Web of Science and the Cochrane Centre Register of Controlled Trials from inception to 6 May 2024.Eligibility criteria for selecting studies Full-text RCTs published in English assessing the effectiveness of any anti-inflammatory dietary intervention (ie, a diet that emphasises the intake of nutrient-rich, minimally processed foods rich in polyphenols, carotenoids and omega-3 polyunsaturated fatty acids and limits highly-processed, pro-inflammatory foods) on HRQOL in adults with at least one chronic disease were included.Methods Data extraction, risk-of-bias assessments and strength-of-evidence assessments were done by two independent reviewers. …”
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7938
Carpaine ameliorates synovial inflammation by promoting p65 degradation and inhibiting the NF-κB signalling pathway
Published 2025-04-01“…Various antibodies and reagents were sourced from Sigma-Aldrich, Abcam, and other suppliers. …”
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7939
Dietary exposure to nitrites and nitrates in association with type 2 diabetes risk: Results from the NutriNet-Santé population-based cohort study.
Published 2023-01-01“…<h4>Background</h4>Nitrites and nitrates occur naturally in water and soil and are commonly ingested from drinking water and dietary sources. They are also used as food additives, mainly in processed meats, to increase shelf life and to avoid bacterial growth. …”
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7940
Differentiating Latent Tuberculosis from Active Tuberculosis Through Activation Phenotypes and Chemokine Markers HLA-DR, CD38, MCP-1, and RANTES: A Systematic Review and Meta-Analy...
Published 2025-01-01“…Design: This study was conducted in accordance with the PRISMA guidelines for systematic reviews and meta-analyses of diagnostic studies. Data sources and methods: We conducted a comprehensive search of PubMed, Scopus, Sciences Direct, and Web of Science for primary studies published in English up to 2023. …”
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