Search for molecular descriptors and computer prediction of biological activity in a series of S-derivatives (1,2,4-triazole-3(2H)-yl)methyl)thiopyrimidines by Yu. V. Karpenko, O. I. Panasenko, A. P. Litun

“…In silico techniques are currently widely used to evaluate the interactions of emerging drug candidates with pharmacological conditions and predict their metabolic conversions. …”
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FORMATION OF INFORMATION CULTURE IN STUDENTS OF ENGINEERING AND PEDAGOGICAL AREAS OF EXPERTISE DURING THEIR VOCATIONAL TRAINING by Sliusarenko Mykola, Filatov Sergiy

“…The study examines the problem of the content and structure of the students’ information culture in engineering and pedagogical areas of expertise, as well as directions, methods and technologies of its formation during their professional training. …”
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Multilingual competency and academic performance: a machine learning-based analysis of the 2022/2023 Somaliland national primary exam data by Jibril Abdikadir Ali, Mustafe Khadar Abdi, Tawakal Abdi Ali, Abdisalan Hassan Muse, Mukhtar Abdi Omar, Mukhtaar Axmed Cumar

“…The study analyzed national examination data from 20,638 students who participated in the 2022/2023 Grade 8 national exams, sourced from the Somaliland National Examination and Certification Board (NECB). …”
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Vitamin D levels and its influencing factors in children and adolescents in mainland China: a systematic review and meta-analysis by Bo Chen, Pengyun Ji, Zisheng Li, Wenyan Qin, Youqing She

“…This study aims to systematically evaluate vitamin D nutritional status among children and adolescents in Mainland China through a quantitative analysis of literature, providing evidence-based strategies for prevention.Design This is a systematic review and meta-analysis, conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.Data sources A comprehensive search strategy was implemented across eight electronic databases (PubMed, Embase, Web of Science, Cochrane Library, CNKI, VIP, Wanfang and CBM) from inception to February 2024.Eligibility criteria We included cross-sectional studies that measured serum 25-hydroxyvitamin D levels and analysed influencing factors (eg, age, season, region) in healthy children and adolescents aged 0–18 years in Mainland China; studies reporting prevalence data of vitamin D deficiency/insufficiency based on standardised thresholds (deficiency <50 nmol/L, insufficiency 50–75 nmol/L) and using validated detection methods (eg, liquid chromatography-tandem mass spectrometry, chemiluminescence immunoassay, ELISA) were prioritised.Data extraction and synthesis Two independent reviewers systematically searched, screened and extracted data using predefined protocols. …”
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Effectiveness of school food environment policies on children's dietary behaviors: A systematic review and meta-analysis. by Renata Micha, Dimitra Karageorgou, Ioanna Bakogianni, Eirini Trichia, Laurie P Whitsel, Mary Story, Jose L Peñalvo, Dariush Mozaffarian

“…Significant sources of heterogeneity or publication bias were not identified.…”
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The effects of air pollutants and meteorological factors on the occurrence and regression of coronary artery lesions in Kawasaki disease: a study combining case-control and cohort... by Yinan Yang, Yanxia Zhang, Shuhong Cai, Dan Wang, Muhua Liao, Xi Chen, Jiaxian Zhou, Huitao Meng, Xiaobin Hu

“…The meteorological data were sourced from the China Meteorological Data Network, including the daily average temperature and the daily average relative humidity. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Single-cell data were sourced from the Tumor Immune Single-cell Hub (TISCH). …”
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Analyzing the level of river sediment pollution with heavy metals using Geo-accumulation Index and Enrichment Factor by Sepehr Akhlaghifard, Toraj Nasr Abadi, Hassan Hoveidi

“…The purpose of this research is to measure the concentration of heavy metals in the sediments of the river bed and to evaluate and analyze it using Geoaccumulation index and Enrichment Factor, which led to the suggested solutions in order to avert and control the further spreading of pollution.Material and Methods: In this research, nine stations were selected based on the land use of the area. …”
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The effectiveness of nurse-led palliative care needs assessment on patients’ quality of life and symptom burden: a systematic review by Gursharan K. Singh, Claudia Virdun, Megan Rattray, Roslyn Prichard, Rochelle Wynne

“…Methods: A systematic review of English language, randomised controlled trials, conducted in May 2023, and updated in April 2024, on the impact of nurse-led palliative care needs assessment was undertaken. …”
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Israeli Youth Pilgrimages to Poland. Rationale and Polemics by Dan Soen, Nitza Davidovich

“…It was this new attitude to the sources of Israeli identity that led to the commencement of trips to Poland by adolescents in the 1980s. …”
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Nurses' occupational fatigue level and risk factors: A systematic review and meta-analysis. by Rong Pi, Yunfang Liu, Rong Yan, Zong De, Yali Wan, Yi Chen, Zihan He, Fang Liu, Yan Wang, Suyun Li

“…Subgroup analysis was conducted to explore sources of heterogeneity. The registration PROSPERO number is CRD42023456337.…”
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Identification of hypoxia-related diagnostic biomarkers and immune signatures in diminished ovarian reserve by Minxue Song, Lili Ni, Zebing Ma, Xin Zhong, Yibing Liu, Jilin Kuang, Ping Li

“…This study investigated the genetic links between hypoxia and DOR.MethodsThe GSE87201 dataset for DOR was sourced from Gene Expression Omnibus database, normalized for common differentially expressed genes (Co-DEGs), and identified Hypoxia-related differentially expressed genes (HRDEGs) via GeneCards; Receiver Operating Characteristic (ROC) curves evaluated HRDEGs’ diagnostic value, and protein-protein interaction networks were visualized with STRING and Cytoscape. …”
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The economic and social burden of pediatric cerebral palsy in Spain: a cost-of-illness study by Diana Marcela Nova-Díaz, Paloma Arana-Rivera, Eduardo Sánchez-Iriso, Sergio Aguilera-Albesa

“…This study aims to classify and estimate the economic and social costs of pediatric CP in Spain from a societal perspective, considering healthcare, government, and family burdens. Additionally, it evaluates the caregiving burden experienced by primary caregivers.MethodsA bottom–up, disease-specific COI study was conducted from a societal perspective using data from a population-based epidemiological registry of CP. …”
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Twenty-year outcomes after repeat doses of antenatal corticosteroids prior to 32 weeks' gestation: Follow-up of a randomised clinical trial. by Robyn W May, Anthony G B Walters, Greg D Gamble, Caroline A Crowther, Stuart R Dalziel, Carl L Eagleton, Christopher J D McKinlay, Barry J Milne, Jane E Harding

“…However, this may have been too early to evaluate potential adverse effects on respiratory and other long-term outcomes. …”
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The Effectiveness and Complication Rate of Resorbable Biopolymers in Oral Surgery: A Systematic Review by Riccardo Fabozzi, Francesco Bianchetti, Domenico Baldi, Catherine Yumang Sanchez, Francesco Bagnasco, Nicola De Angelis

“…PEG-based membranes were found to perform on par with or occasionally better than traditional collagen membranes derived from porcine sources. Additionally, the application of 3D-printable polymers demonstrated promise in site-specific healing. …”
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CONSORT 2025 statement: Updated guideline for reporting randomised trials. by Sally Hopewell, An-Wen Chan, Gary S Collins, Asbjørn Hróbjartsson, David Moher, Kenneth F Schulz, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A Berlin, Nita Bhandari, Nancy J Butcher, Marion K Campbell, Runcie C W Chidebe, Diana Elbourne, Andrew Farmer, Dean A Fergusson, Robert M Golub, Steven N Goodman, Tammy C Hoffmann, John P A Ioannidis, Brennan C Kahan, Rachel L Knowles, Sarah E Lamb, Steff Lewis, Elizabeth Loder, Martin Offringa, Philippe Ravaud, Dawn P Richards, Frank W Rockhold, David L Schriger, Nandi L Siegried, Sophie Staniszewska, Rod S Taylor, Lehana Thabane, David Torgerson, Sunita Vohra, Ian R White, Isabelle Boutron

“…<h4>Conclusions</h4>Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomised trials to ensure that trial reports are clear and transparent.…”
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Association Between Sarcopenia Susceptibility and Cesarean Section: A Study Based on National Health and Nutrition Examination Survey (NHANES) and Mendelian Randomization by Tian F, Pan H, Wu Q, Jiang D

“…Two-sample bidirectional MR was employed to evaluate causal relationships. Genetic data associated with CS (n=462,933) and appendicular lean mass (ALM, n=450,243) were sourced from the largest genome-wide association studies (GWAS). …”
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Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients by Zi-han Gou, Nan Su, Xiao-chuan Li, Da-peng Ren, Shan-shan Ren, Lin Wang, Yao Wang

“…Gene expression data were sourced from the GSE163943 dataset in the Gene Expression Omnibus (GEO) database. …”
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Benefits of Early Enteral Feeding with a Locally Prepared Protein-Energy Ration after Surgery for Acute Generalised Peritonitis: A Randomised Trial in Two Hospitals in Bukavu, East... by Jean Paul Buhendwa Cikwanine, Jonathan Tunangoya Yoyu, Désiré Munyali Alumeti, Bernard Mugisho, John Mutendela Kivukuto, Rivain Fefe Iteke, Ona Longombe Ahuka, Willy Kalau Arung

“…Conclusion. EEF with locally sourced protein-energy rations can enhance a patient’s nutritional status and facilitate postoperative recovery. …”
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Development of a warning model for drug-induced liver injury in the older patients by Qiaozhi Hu, Qiaozhi Hu, Xiaoqi Li, Xiaoqi Li, Dan Zou, Zhiyao He, Zhiyao He, Ting Xu

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