Early determination of potential critical quality attributes of therapeutic antibodies in developability studies through surface plasmon resonance-based relative binding activity a... by Shuai Wang, Yanqiu Wang, Zhenzhen Li, Ye Hong, Zhaohui Wang, Jiteng Fan, Qiong Wang, Yuanjie Ge, Xiaofeng Zhao, Guangcun Cheng, Changyan Chen, Yadan Wu, Yayuan Fu

“…We identified several potential CQAs, including Asp isomerization, Asn deamidation, and fragmentation. Some potential CQAs affected binding affinity of antibody and resulted in a reduction of binding activity. …”
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Unraveling the spatiotemporal dynamics and drivers of surface and tropospheric ozone in China by Shuai Yin, Chong Shi, Husi Letu, Zhijun Jin, Qingnan Chu, Huazhe Shang, Dabin Ji, Meng Guo, Kunpeng Yi, Xin Zhao, Tangzhe Nie, Zhongyi Sun

“…These findings imply that the current mitigation strategy still has some insufficiencies, and to reduce the exposure risk in the future, China needs to set more ambitious mitigation targets and continue to push forward and strengthen the synergetic control of multiple air pollutants.…”
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In Vitro Assessment of <i>Penicillium expansum</i> Sensitivity to Difenoconazole by Mohammed Khadiri, Hassan Boubaker, Abdelaaziz Farhaoui, Said Ezrari, Mohammed Radi, Rachid Ezzouggari, Fouad Mokrini, Essaid Ait Barka, Rachid Lahlali

“…Moreover, the results indicate that 46 isolates were able to develop even at a concentration of 5 µg/mL of Dif (the suggested discriminatory dose), indicating reduced sensitivity to this fungicide. The analysis of the values of the effective concentration to inhibit 50% (EC50) of mycelial growth of <i>P. expansum</i> ranging from 0.027 to 1.673 µg/mL (mean: 0.263 µg/mL, variation factor: 62.507) and for spore germination from 0.0002 to 0.787 µg/mL (mean: 0.048 µg/mL, variation factor: 4113.835). …”
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Predicting Immunogenic Epitopes Variation of Envelope 2 Gene Among Chikungunya Virus Clonal Lineages by an In Silico Approach by Sung-Yeon Cho, Dong-Gun Lee, Jung Yeon Park, Won-Bok Kim, Raeseok Lee, Dukhee Nho, Eun-Jee Oh, Hyeyoung Lee, Chulmin Park

“…Phylogenetic analysis revealed distinct geographically distributed clonal lineages (clades I-IV). …”
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Uncovering the importance of soil type, landscape connectivity, and pedodiversity for nature’s contributions to people in a typical agricultural region by Guangyi Deng, Haibo Jiang, Yang Wen, Chunguang He, Lianxi Sheng, Dehai Gu, Shuai Ma

“…Landscape connectivity and pedodiversity were identified as critical determinants of NCP levels, in some cases exceeding the influence of climate and vegetation. …”
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Genotyping by sequencing reveals the genetic diversity and population structure of Peruvian highland maize races by Carlos I. Arbizu, Carlos I. Arbizu, Isamar Bazo-Soto, Joel Flores, Rodomiro Ortiz, Raul Blas, Pedro J. García-Mendoza, Ricardo Sevilla, José Crossa, Alexander Grobman

“…Population structure analysis indicated that these 423 distinct genotypes can be included in 10 groups, with some maize races clustering together. …”
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Using Continuous Flight Auger Pile Execution Energy to Enhance Reliability and Reduce Costs in Foundation Construction by Darym Júnior Ferrari de Campos, José Camapum de Carvalho, Paulo Ivo Braga de Queiroz, Luan Carlos Sena Monteiro Ozelim, José Antonio Schiavon, Dimas Betioli Ribeiro, Vinicius Resende Domingues

“…It shows that considering fixed-length piles may not favor safety, as the energy-based analysis revealed that some piles needed longer shafts. …”
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Comparison of machine learning models for coronavirus prediction by B. K. Amos, I. V. Smirnov, M. M. Hermann

“…It is a family of viruses ranging from the common cold to severe acute respiratory syndrome (SARS). …”
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Quantification of Phenolic Compounds in Olive Oils by Near-Infrared Spectroscopy and Multiple Regression: Effects of Cultivar, Hydroxytyrosol Supplementation, and Deep-Frying by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

“…The results show that HTyr ranged from 7.28 mg/kg in Manzanilla (lowest) to 21.43 mg/kg in Royuela (highest). …”
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« Paroles de flics ». Communications policières et actualité politique au Maroc (2005-2023) by Mériam Cheikh

“…Without going into the details of the 101 issues of Police Magazine and Revue de Police under review (the space available does not allow for text analysis), the aim is to highlight the most significant elements that demonstrate the stages of opening up and then of closing down of the police’s discourse on itself. …”
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Teledentistry for Improving Access To, and Quality of Oral Health Care: Overview of Systematic Reviews and Meta-Analyses by Pascaline Kengne Talla, Paul Allison, André Bussières, Anisha Rodrigues, Frédéric Bergeron, Nicolas Giraudeau, Elham Emami

“… Abstract BackgroundDigital interventions including teledentistry are promising approaches to address some of the inadequacies of health care systems. …”
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Genotype by environment interactions and phenotypic traits stability of the EUCLEG faba bean collection by Dejan Sokolović, Snežana Babić, Mirjana Petrović, Ignacio Solís, Mathias Cougnon, Natalia Gutierrez, Pertti Pärssinen, Dirk Reheul, Jasmina Radović, Ana M. Torres

“…Hierarchical cluster analysis and principal component analyses showed a clear correlation between the traits analysed and the botanical type. …”
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A comprehensive study of respiration rates in dairy cattle in a Mediterranean climate by Grazyne Tresoldi, Mina Hejazi, Cassandra B. Tucker

“…The likelihood of upper normal RR values (30–50 breaths/min, according to some textbooks) was highest when air temperatures (AT) were below 20 to 25°C, depending on the life stage. …”
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Closeby Habitable Exoplanet Survey (CHES). IV. Synergy between Astrometry and Direct Imaging Missions of the Habitable World Observatory for Detecting Earth-like Planets by Chunhui Bao, Jianghui Ji, Dongjie Tan, Guo Chen, Xiumin Huang, Su Wang, Yao Dong

“…Under the adopted detection limit, our analysis indicates that prior CHES observations can increase completeness by approximately 10% and improve detection efficiency by factors ranging from 2 to 30. …”
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Temporary 2-week suspension of methotrexate treatment to enhance COVID-19 vaccine response in people with immune-mediated inflammatory diseases: the VROOM RCT by Abhishek Abhishek, Nicholas Peckham, Corinna Pade, Joseph M Gibbons, Lucy Cureton, Catherine J Reynolds, Anne Francis, Vicki Barber, Jennifer Williams, Duncan Appelbe, Lucy Eldridge, Patrick Julier, Daniel M Altmann, James Bluett, Tim Brooks, Laura C Coates, Ines Rombach, Amanda Semper, Ashley Otter, Ana M Valdes, Jonathan S Nguyen-Van-Tam, Hywel C Williams, Rosemary J Boyton, Áine McKnight, Jonathan A Cook

“…We did not have data for memory B-cell and T-cell responses. Some hospitals declined to participate in the 26-week follow-up visit which was added to the study after interim analysis, due to lack of capacity, contributing to increased attrition at week 26. …”
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Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review by Joy Duxbury, Alina Haines-Delmont, John Baker, Peter Baker, Gary Bourlet, Elaine Craig, James Ridley, Rachel Whyte, Beth Morrison, Michaela Thomson, Anthony Tsang, Tella Lantta

“…Background There is some evidence to support approaches to reduce restrictive practices in settings for people with a learning disability who may also have a diagnosis of autism or mental health problems. …”
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Assessing Habitat Suitability for the Invasive Species Lantana camara on Bali Island: A Model Using the Biodiversity and Climate Change Virtual Laboratory (BCCVL) by Rajif Iryadi, Sutomo, Muhammad Hadi Saputra, Nida Humaida, Eko Pujiono, Jalma Giring Sukmawati, Aditya Hani, Komang Kartika Indi Swari, Dewa Ayu Intan Sari, Muhammad Bima Atmaja, Wieke Herningtyas, Reni Setyo Wahyuningtyas, Eddie van Etten

“…Potential improvements through additional environmental parameters were suggested. While L. camara has some potential benefits as a medicinal plant in Balinese culture, its invasive nature poses significant threats to native ecosystems. …”
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In Vitro Evidence for the Efficacy of Manuka Honey and Its Components Against the Major Human Pathogenic <i>Sporothrix</i> Species by Andrea Reis Bernardes-Engemann, Fernando Almeida-Silva, Levi G. Cleare, Jefferson D. da Cruz, Jefferson Rocha de A. Silva, Walter Sotto M. Fernandes Neto, Rosely Maria Zancopé-Oliveira, Ana Claudia Fernandes Amaral, Joshua D. Nosanchuk, Rodrigo Almeida-Paes

“…In recent years, the observation of reduced treatment effectiveness in some patients has arisen, possibly due to <i>Sporothrix</i> spp. resistance mechanisms. …”
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Cadmium Bioavailability Based on Diffusive Gradients in Thin Films Technique and Conventional Chemical Extraction in High Geological Background Soil Area of Northwestern Zhejiang P... by Chao WU, Binbin SUN, Xiaomeng CHENG, Dong LIU, Yu QIAO, Ling He, Daoming ZENG

“…Studies have shown that \begin{document}$ {{C}}_{{\text{CaCl}}_{\text{2}}} $\end{document} solution can effectively replace metal ions adsorbed by soil particles, and the change of soil pH and soil structure has little effect on the replacement rate, giving it a wide range of applications. \begin{document}$ {{C}}_{{\text{CaCl}}_{\text{2}}} $\end{document} solution mainly displaces the adsorbed Cd from soil through static ion exchange, and the extracted available Cd is mainly water-soluble and exchangeable Cd, but some bioavailable metals in soil (such as soil particles or unstable organic/inorganic complexes in soil solution) may not be extracted, so the bioavailability of Cd in soil may be underestimated…”
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Pulmonary aspergillosis in US Veterans with COVID-19: a nationwide, retrospective cohort study by Kaitlin Swinnerton, Nathanael R. Fillmore, Ikwo Oboho, Janet Grubber, Mary Brophy, Nhan V Do, Paul A Monach, Westyn Branch-Elliman

“…Conclusions: Patients with underlying risk factors for invasive aspergillosis continue to be at some risk despite SARS-CoV-2 immunization. Risk in patients without immune suppression or preexisting lung disease is very low. …”
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