Novel Copper(II) Coordination Compounds Containing Pyridine Derivatives of <i>N</i>⁴-Methoxyphenyl-Thiosemicarbazones with Selective Anticancer Activity by Roman Rusnac, Olga Garbuz, Victor Kravtsov, Elena Melnic, Dorin Istrati, Victor Tsapkov, Donald Poirier, Aurelian Gulea

“…The molecular structure of four compounds was investigated using single crystal X-ray diffraction. Spectral analysis techniques such as FT-IR, ¹H NMR, ¹³C NMR, elemental analysis, and molar conductivity were used for all the synthesized compounds. …”
Get full text

MIRI-LRS Spectrum of a Cold Exoplanet around a White Dwarf: Water, Ammonia, and Methane Measurements by Maël Voyer, Quentin Changeat, Pierre-Olivier Lagage, Pascal Tremblin, Rens Waters, Manuel Güdel, Thomas Henning, Olivier Absil, David Barrado, Anthony Boccaletti, Jeroen Bouwman, Alain Coulais, Leen Decin, Adrian M. Glauser, John Pye, Alistair Glasse, René Gastaud, Sarah Kendrew, Polychronis Patapis, Daniel Rouan, Ewine F. van Dishoeck, Göran Östlin, Tom P. Ray, Gillian Wright

“…We observed WD 0806-661 b using JWST’s Mid-InfraRed Instrument Low-Resolution Spectrometer, covering the wavelength range from 5 to 12 μ m, and the Imager, providing us with 12.8, 15, 18, and 21 μ m photometric measurements. …”
Get full text

OrthoticS for TReatment of symptomatic flat feet In CHildren (OSTRICH): a randomised controlled trial by Sarah Cockayne, Kalpita Baird, Sally Gates, Caroline Fairhurst, Joy Adamson, Rachel M Bottomley-Wise, Amie Woodward, Michael R Backhouse, Rachel Bye, Nina Davies, Catherine Hewitt, Colin Holton, Peter Knapp, Anne-Maree Keenan, Stewart Morrison, Daniel Parker, Daniel C Perry, Sarah Ronaldson, Mark Smith, Tim Theologis, Victoria Exley, Jane McAdam, David J Torgerson

“…The mean age of participants was 10.6 years (range 6.3–14.8) and 55.2% were male. No adverse events were reported. …”
Get full text

SEGS-1 episomes generated during cassava mosaic disease enhance disease severity by Evangelista Chiunga, Evangelista Chiunga, Evangelista Chiunga, Catherine D. Aimone, Cyprian Rajabu, Mary M. Dallas, Joseph Ndunguru, José T. Ascencio-Ibáñez, Elijah M. Ateka, Linda Hanley-Bowdoin

“…Susceptible cultivars developed severe CMD with or without exogenous SEGS-1, while exogenous SEGS-1 increased disease severity in cultivars carrying CMD2 resistance, which is conferred by a single locus, but not CMD1 resistance, which is polygenic. Analysis of infected plants in the absence of exogenous SEGS-1 revealed that some, but not all, cultivars form SEGS-1 episomes during CMD. …”
Get full text

Slope—sedimentary source rock-type helium enrichment model: a case study of Shenmu Gas Field, Ordos Basin by Zhengang DING, Chenglin LIU, Liyong FAN, Rui KANG, Jianfa CHEN, Haidong WANG, Sijie HONG, Aslam Khan MUHAMMAD

“…The results showed that the helium content in the Upper Paleozoic of the Shenmu Gas Field ranged from 0.017% to 0.116%, with an average content of 0.05%, meeting the standard of a helium-containing gas field. …”
Get full text

Hemorrhagic disease of the newborn: modern approaches to diagnosis, prevention and treatment by E. M. Rashkova, A. A. Shakirova, H. A. Sarkisyan, L. A. Levchenko, S. V. Cherkasova, E. I. Shabelnikova

“…Depending on the age of onset, early is distinguished – it manifests itself in the first 24 hours of life, classical – develops on the 2-7th day and late, manifesting itself after 1 week of life (rarely occurs at the age of up to 6 months of life, and some authors indicate the age children under 1 year of age) hemorrhagic disease of the newborn forms. …”
Get full text

When do citizen scientists record biodiversity? Non‐random temporal patterns of recording effort and associated factors by Inês T. Rosário, Patrícia Tiago, Sergio Chozas, César Capinha

“…Recording activity was higher on weekends, to some extent on Fridays and during the spring months. …”
Get full text

Relationship of the Critical Care Pain Observation Tool Score With the APACHE II Score, Sedation Level, and Ventilation Parameters in Critically Ill Patients Under Mechanical Venti... by Zohreh Akbari, Ali Asghar Jesmi, Neda Mahdavifar, Ali Taj, Shakiba Mozari

“…Objective: This study aims to evaluate the correlation of pain intensity with the acute physiology and chronic health evaluation (APACHE II) score, the Ramsay sedation scale (RSS) score, and some ventilation parameters in patients under mechanical ventilation admitted to the ICU.  …”
Get full text

Symptom variability in outpatients with COPD and validation of the Colombian COPD Symptom Variability Instrument (EPOC-CoVaSy) by Eidelman Antonio González-Mejía, Olga Constanza Uñate-Suárez, Carlos José Bula- Gutiérrez, Yojana Patricia Patiño-Jiménez

“…Results: Participants’ mean age was 73.3±8.3 years and 71.87% were male. According to the analysis of the diaries, the mean scores (visual analog scale) for all symptoms and the performance of activities of daily living ranged between 0.5 and 2.5, being higher in the morning (mean scores between 1.5 and 2.5) than in the afternoon and night (mean scores between 0.5 and 1.5); however, symptom variability was minimal. …”
Get full text

Potential confounding mutations in Keio knockout strains: implications for research accuracy by Oishi Sen, Xianghui Liu, Staffan Kjelleberg, Scott A. Rice, Thomas Seviour

“…A small number of SNPs and INDELs were predicted in the coding and intergenic regions of the knock-out mutants in comparison to the parental strain through sequencing and bioinformatic analysis. Mutations in the coding regions of genes (different from the actual gene knocked out in the mutants) led to different types of mutations in the affected genes, ranging from nonsense mutations to frameshift mutations, which could affect the functionality of the resulting gene products. …”
Get full text

Sick Child Feeding Practice and Associated Factors among Mothers of Children Less Than 24 Months Old, in Burayu Town, Ethiopia by Nega Degefa, Hiwot Tadesse, Fekadu Aga, Tomas Yeheyis

“…Growing evidence suggests that inadequate intake, poor caring practices, and disease process were some of the immediate and major causes of undernutrition in children. …”
Get full text

In silico identification of potential inhibitors for the universal stress G4LZI3 protein from Schistosoma mansoni using molecular docking and molecular dynamics simulation analyses by Lihle Mahamba, Mustafa Alhaji Isa, Abidemi Paul Kappo

“…Control efforts primarily rely on health education, improved sanitation, snail host management, and mass drug administration with Praziquantel (PZQ). PZQ has some limitations, such as its lower effectiveness against immature parasites and the potential for developing resistance. …”
Get full text

Using the Q-method to explore pregnant and breastfeeding women’s perceptions of antibiotic use in Mahajanga, Northwest Madagascar by Sitraka Rakotosamimanana, Aina Harimanana, Timothée Razafindrabesa, Voahirana Ravololomihanta, Laurent Kapesa, Chiarella Mattern, Daouda Kassié

“…Principal component analysis (PCA) was used to analyze the rankings and identify groups of women with differing or similar viewpoints. …”
Get full text

Charge transfer complexes: a review survey by Vahideh Hadigheh Rezvan

“…These complexes exhibit unique properties that distinguish them from traditional ionic, covalent, and coordination bonds. Some CTCs, especially those involving drugs, possess biological properties such as antibacterial and antiviral effects; experimental and molecular docking studies have been conducted. …”
Get full text

Variability in knowledge retention of medical students: repeated and recently learned basic science topics by Gergely Csaba, István Szabó, József L. Környei, Mónika Kerényi, Zsuzsanna Füzesi, Árpád Csathó

“…Retention rates varied significantly, with values ranging from 54.5 to 97.2%. Microbiology revealed better results of first-semester content compared to the second semester in some of the retention measures, while physiology showed no difference between semesters. …”
Get full text

Plasmid diversity of Serratia marcescens and Klebsiella pneumoniae isolates involved in two carbapenem-resistant Enterobacteriaceae outbreaks in a Swiss hospital by Florian Mauffrey, Claire Bertelli, Gilbert Greub, Bruno Grandbastien, Laurence Senn, Dominique S. Blanc

“…Plasmids showed close relatedness within and across patient and environmental isolates, with core SNP distances ranging from 0 to 18. Some blaNDM-1 plasmids in K. pneumoniae clustered tightly, suggesting persistence and potential cross-contamination routes. …”
Get full text

Influence of oromotor functions on motor development and feeding outcomes in children with cerebral palsy by Amira F. Ibrahim, Sara Y. Elsebahy, Monira I. Aldhahi, Mai M. Khalaf, Ahmed A. Torad, Mona Mohamed Taha, Amira F. El-Sheikh

“…This study aimed to investigate the relationship between the level of gross motor function, feeding level, oromotor structural dysfunction, tongue thrust, and eating performance in children with cerebral palsy (CP).Patients/materials and methods This cross-sectional study included a total of fifty-five children diagnosed with spastic diplegic cerebral palsy, with a mean age of 4.84  years and a mean weight of 12.46  kg. Participants’ ages ranged from 2 to 14  years. All patients underwent evaluations to determine their level of gross motor function using the Gross Motor Function Classification System (GMFCS), feeding level assessed using the Functional Oral Intake Scale, assessment of oromotor structural dysfunction using the Orofacial Motor Functional Assessment Scale, tongue thrust using the Tongue Thrust Rating Scale, and feeding performance using the Oral Motor Assessment Scale.Results Correlational analysis revealed that children with better gross motor function tended to exhibit improved feeding levels, orofacial motor function, and feeding performance (p < 0.05); however, no significant relationship was observed between gross motor function and tongue thrust. …”
Get full text

Impacts of National Reimbursement Drug Price Negotiation on drug accessibility, utilization, and cost in China: a systematic review by Zheng Zhu, Jiawei Zhang, Zhihu Xu, Quan Wang, Yu Qi, Li Yang

“…Most of the studies (66%, n = 12) have some limitations (unclear risk of bias). The published studies indicated the implementation of the NRDPN policy decreased drug prices, ranging from 24 to 72%, which increased the affordability of success-negotiated drugs (refer to those medications that have undergone a successful price negotiation process between pharmaceutical companies and healthcare authorities) and decreased out-of-pocket expenditures. …”
Get full text

Barriers and Facilitators to Medicines Use in Patients With Vision Impairment: A Theory‐Informed Qualitative Study of Patients and Caregivers by Basma Y. Kentab, Heather E. Barry, Sinaa A. Al‐Aqeel, Carmel M. Hughes

“…Caregivers played a major role in assisting patients with medicines. Participants had some positive encounters with pharmacists but reported difficulties in discussing medication issues with them. …”
Get full text

Design and parameter optimization of portable tree transplanting machine by Zhang Jingping, Zhu Jianxi, Sun Teng

“…Furthermore, the format of the vibration shovel was suitable to some different trees whose diameter ranged from 100 mm to 200 mm. …”
Get full text