The unexploited potential of data systems tracking medicines utilization: an opportunity to improve access to oncology combination therapies by Steven Simoens, David Dodwell, Michael Hartevelt, Peter Lindgren, Peter Lindgren, Michele Pistollato, Lisa Pont, Caridad Pontes, Alexander Roediger, Antun Sablek, Eric Van Ganse, Qinyi Wang, Chris Wenger, Tim Wilsdon, Entela Xoxi, Entela Xoxi, Brian Godman, Brian Godman

“…The feasibility of this solution requires data on the utilization of combination therapies.AimTo investigate the ability of data systems across Belgium, England, France, Italy, Spain, Sweden, Switzerland and Australia to track drug utilization of combination therapies, particularly in oncology.MethodsA targeted literature review was conducted to investigate the attributes of the key data systems. …”
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Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii by Maria Romano, Federico Falchi, Federico Falchi, Eliana De Gregorio, Maria Stabile, Antonella Migliaccio, Alessia Ruggiero, Valeria Napolitano, Ida Autiero, Flavia Squeglia, Rita Berisio

“…The best ligand was tested for its ability to hamper colistin resistance in Acinetobacter baumannii clinical isolates. …”
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APPLICATION OF LEUKOCYTE FILTERS TO OBTAIN A PREPARATION OF CYTOKINE-INDUCED KILLER CELLS by Yu. V. Gelm, L. Yu. Grivtsova, E. V. Sayapina, N. S. Semenova, T. Yu. Mushkarina, S. A. Ivanov, A. D. Kaprin

“…AbstractThe ability of CIK cells to recognize and lyse tumor cells has been demonstrated in preclinical studies in vitro. …”
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Investigating Falls Risk Awareness in Hospitals Using the Self‐Awareness of Falls Risk Measure (SAFRM): Empirical Research Quantitative by Elissa Dabkowski, Simon J. Cooper, Jhodie Duncan, Karen Missen

“…An exploratory factor analysis (EFA) revealed a three‐factor solution from section A of the SAFRM, which were labelled Physical Activity Awareness, Cognitive Awareness and Balance Awareness. …”
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Post-harvest processing methods have critical roles on the contents of active metabolites and pharmacological effects of Astragali Radix by Xiaoyan Zhang, Shengnan Jiang, Tingting Sun, Wenbing Zhi, Kairu Ding, Ziyao Qiao, Hong Zhang, Hong Zhang, Ye Li, Yang Liu, Yang Liu

“…The entropy weight method, combined with the technique for order preference by similarity to ideal solution (TOPSIS), was employed to optimize the fresh processing method. …”
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Role of BDNF-TrkB signaling pathway in early-life cadmium exposure induced cognitive dysfunction in mice by Yan SHI, Siqi YANG, Yougang WANG, Qiumei WU, Jinquan LI

“…The cadmium content in brain was detected and the learning and memory ability was tested by Y maze and Morris water maze to evaluate cognitive function of offspring mice. …”
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An improved bacterial single-cell RNA-seq reveals biofilm heterogeneity by Xiaodan Yan, Hebin Liao, Chenyi Wang, Chun Huang, Wei Zhang, Chunming Guo, Yingying Pu

“…This innovative approach offers a cost-effective, equipment-free, and high-throughput solution for bacterial single-cell RNA sequencing (scRNA-seq). …”
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Smartphone-Based Telemonitoring for Better Oral Health With Toothbrushes: 6-Month Randomized Controlled Trial by Jaeyeon Kim, Yiseul Choi, Yoolbin Song, Wonse Park

“… BackgroundA toothbrush device that telemonitors toothbrushing is a technologically advanced solution providing personalized feedback on toothbrushing habits and oral hygiene. …”
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Morphometric changes in the heart of rats with alloxan and streptozotocin diabetes by Saule Zhautikova, Kulash Nurseitova, Lyubov Piven, Tatyana Kim, Irina Baryshnikova, Gulnur Bakaramova, Arailym Amantayeva, Zhadyra Orynbayeva

“…In diabetes mellitus (DM), the ability of the myocardium to fully relax and fill with blood during diastole is impaired. …”
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DEVELOPMENT OF PRACTICAL SKILLS IN FOREIGN STUDENTS DURING EDUCATION AT THE DEPARTMENT OF PROPEDEUTICS OF SURGICAL DENTISTRY by I.A. Kolisnyk, A.I. Pankevych, A.M. Hohol, V.M. Novikov, E.Yu. Rezvina, M.A. Korostashova

“…The assimilation of theoretical material, the ability to analyze, search and process the received information are definitely important goals, however, the content of medical education cannot be reduced to only theoretical knowledge, but must ensure the mastery of practical skills. …”
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Response of rumen methane production and microbial community to different abatement strategies in yaks by Qian Zhang, Tongqing Guo, Xungang Wang, Lin Wei, Yalin Wang, Shanshan Li, Hongjin Liu, Na Zhao, Shixiao Xu

“…The selected strategies—Sodium Nitrate solution, regional Medicago sativa L., and regional Helianthus tuberosus L.…”
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Biological prerequisites for the introduction of health-saving technologies in the process of adaptive physical education of schoolchildren with visual impairments by Bozhena Bukhovets, Galyna Dyshel, Petro Todorov, Inna Asauliuk, Vitaly Usychenko

“…Summing up the final analysis of the studied indicators on a sample of 12-year-old schoolchildren with visual impairments, it showed that the three-factor solution turned out to be the most informative and covers 83,14%. …”
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political thought of Sayyed Ahmad Barilavi by Mohammad Ali Mir Ali, mohammad shojaiyan, Sayed Yahya Mosavi

“…The core question of this inquiry is: according to Sayyid Ahmad Barelvi, what were the crises facing the society of the Indian subcontinent at that time, what did he consider their roots and causes, and what was his ideal political order and the solutions he prescribed for overcoming these crises?…”
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UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN SERAI WANGI (Cymbopogon nardus L.) SECARA IN VITRO DENGAN METODE HRBC (Human Red Blood Cell) by Eni Kartika Sari, Ni Putu Dea Anantarini, Beta Ria Erika Marita Dellima

“…The anti-inflammatory activity test of the ethanol extract of citronella leaves was carried out in vitro based on its effect on the stability of the red blood cell membrane using the HRBC method with blood damaged by a hypotonic solution as the test medium. The results showed that the ethanol extract of citronella leaves had an anti-inflammatory effect from its ability to maintain red blood cell stability, where the higher the concentration, the greater the % stability of red blood cells. …”
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Synergistic Adsorption and Photocatalytic Activity under Visible Irradiation Using Ag-ZnO/GO Nanoparticles Derived at Low Temperature by Viet Ha Tran Thi, The Ha Cao, Tri Nhut Pham, Tien Thanh Pham, Manh Cuong Le

“…Ag-ZnO/graphene oxide (AG-ZnO/GO) nanocomposite was synthesized via facile aqueous solution reactions at low temperature in order to improve the photocatalytic activity for cationic dye removal under visible light irradiation. …”
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Comparison of neutron transport calculation methods based on C5G7-MOX and preliminary analysis of sensitivity of MOC parameters by GONG Hanyuan, ZHANG Binhang, ZHANG Yonghong, TANG Haibo, YUAN Xianbao

“…BackgroundThe Method of Characteristics (MOC) is widely applied to high-fidelity numerical simulations due to its robust geometric processing capabilities, as well as its ability to balance computational costs and accuracy during calculations. …”
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Generative Modeling for Imbalanced Credit Card Fraud Transaction Detection by Mohammed Tayebi, Said El Kafhali

“…Class imbalance often hinders the performance of machine learning models by limiting their ability to learn from minority classes, such as fraudulent transactions. …”
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Charging pile fault prediction method combining whale optimization algorithm and long short-term memory network by Yansheng Huang, Atthapol Ngaopitakkul, Suntiti Yoomak

“…By introducing the whale optimization mechanism to globally optimize the key parameters of the neural network, the method improved the model’s ability to model complex time series data. Moreover, the method also effectively avoided the problem of traditional methods falling into local optimal solutions, thus improving the training efficiency and generalization ability while maintaining the model accuracy. …”
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Monolithic Desktop Digital Fabrication of Autonomous Walking Robots by Yichen Zhai, Jiayao Yan, Albert De Boer, Martin Faber, Rohini Gupta, Michael T. Tolley

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Risk Assessment of Supplier R&D Investment Based on Improved BP Neural Network by Yinghua Song, Xiaoyan Sang, Zhe Wang, Hongqian Xu

“…Seventeen indicators that affect and constrain project investment factors were identified as input variables of the back propagation (BP) neural network, the comprehensive score of the R&D investment risk assessment was used as the output variable of medical supplies suppliers, and a risk assessment model for the R&D investment of medical material suppliers was established. By leveraging the ability of particle swarm optimization (PSO), whale optimization algorithm (WOA), and genetic algorithm (GA) to search for global optimal solutions, the BP neural network is improved to avoid becoming trapped in local optimal solutions and enhance the model’s generalization ability. …”
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