BIOMECHANICAL STUDY OF SINGLE ROOTED TEETH RESTORED WITH DOWEL CORS by M. M. Klepach, B.Y. Silenko, T. A. Khmil, M. V. Khrebor, Y. I. Silenko

“…As a main evaluation criterion when comparing the stress-strain state of considered mathematical models of the system "dowel core- recovery single rooted tooth - lower jaw" should take the maximum values of equivalent stresses in the dowel core and the dentin of the root part of the tooth recoverable, arising from the action of the calculated values of functional loads , since exceeding these tension can cause destruction of the root of the tooth or core. …”
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Uterine Smooth Muscle Tumor of Uncertain Malignant Potential (STUMP) Treated with Conservative Surgery: Systematic Review of Reproductive Outcomes by Martina Arcieri, Stefano Cianci, Canio Martinelli, Silvana Parisi, Stefano Pergolizzi, Vito Andrea Capozzi, Marco La Verde, Carlo Ronsini, Stefano Restaino, Giuseppe Vizzielli, Vittorio Palmara, Roberta Granese, Alfredo Ercoli

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Effects of a WHO-guided digital health intervention for depression in Syrian refugees in Lebanon: A randomized controlled trial. by Pim Cuijpers, Eva Heim, Jinane Abi Ramia, Sebastian Burchert, Kenneth Carswell, Ilja Cornelisz, Christine Knaevelsrud, Philip Noun, Chris van Klaveren, Edith Van't Hof, Edwina Zoghbi, Mark van Ommeren, Rabih El Chammay

“…The guided WHO Step-by-Step intervention we examined should be made available to communities of displaced people that have digital access.…”
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The ubiquitin code of RAS proteins: Decoding its role in cancer progression by Yedan Shi, Yong Shen, Xiuyuan Zhang, Ning Zhu, Yuwei Ding, Ying Yuan, Juan Wang

“…We also analyze the heterogeneity of ubiquitination patterns across distinct RAS isoforms (KRAS4A, KRAS4B, NRAS, and HRAS) and their functional disparities in cancers. Targeting the ubiquitination pathway offers novel strategies to overcome RAS proteins. …”
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Sand nourishment for multifunctional coastal climate adaptation: three key implications for researchers by Haye H. Geukes, Tosca T. Kettler, Eva M. Lansu, Vincent Bax, Solveig Höfer, Matthieu A. de Schipper, Renske de Winter, Arjen P. Luijendijk, Valerie C. Reijers, Peter M. van Bodegom, Wietse I. van de Lageweg, Tjisse van der Heide, Alexander P.E. van Oudenhoven

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The Usefulness of T1-Weighted Magnetic Resonance Images for Diagnosis of Acute Leukemia Manifesting Musculoskeletal Symptoms prior to Appearance of Peripheral Blood Abnormalities by Toshihide Yoshikawa, Akihiko Tanizawa, Koji Suzuki, Nanae Tanaka, Taihei Hayashi, Masayo Tsuda, Genrei Ohta, Naoko Kikuchi, Hiroyuki Okamoto, Takehiko Sakai, Yoshihiro Taniguchi, Yusei Ohshima

“…The patients with acute leukemia occasionally present with musculoskeletal symptoms initially, including bone pain, joint pain, muscular pain, and functional impairment. Without abnormal findings of peripheral blood cell counts or smear, the correct diagnosis tends to be delayed. …”
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Understanding suicidality in adolescents and young adults at clinical high risk for psychosis: a narrative review on risk factors and clinical insights by Maria Pontillo, Cristina Di Vincenzo, Michelangelo Di Luzio, Francesco Demaria, Barbara D’Aiello, Ilaria Bertoncini, Massimo Apicella, Milena Labonia, Gino Maglio, Roberto Averna, Stefano Vicari, Stefano Vicari

“…Key risk factors include prior suicide attempts, impaired social functioning, psychiatric comorbidities, and stigma-related distress. …”
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Physical Activity in Mental Health Disorders – Therapeutic Potential and Mechnisms by Maria Wachowska, Paweł Maciej Rycąbel, Mateusz Romaniuk, Marek Jarosław Molenda, Mateusz Paniak, Wojciech Jan Sowiński, Oliwia, Marta Szymura, Agnieszka Ewelina Wojciechowska, Michał Brunon Krawczyk

“…Aerobic and resistance exercises, as well as yoga, are effective in alleviating depressive symptoms, anxiety, and PTSD, improving ADHD-related cognitive functions, and decreasing substance cravings. This study aims to analyze the influence of physical activity on mental disorders. …”
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Research progress and implications of the application of large language model in shared decision-making in China’s healthcare field by Xuejing Li, Xuejing Li, Xuejing Li, Sihan Chen, Sihan Chen, Sihan Chen, Meiqi Meng, Meiqi Meng, Meiqi Meng, Ziyan Wang, Ziyan Wang, Ziyan Wang, Hongzhan Jiang, Hongzhan Jiang, Hongzhan Jiang, Yufang Hao, Yufang Hao, Yufang Hao

“…Large Language Models (LLMs), with their powerful natural language processing capabilities, demonstrate unique advantages in enhancing communication efficiency, supporting personalized decision-making, and promoting multi-party collaboration. Key functionalities such as information integration, personalized support tools, and sentiment analysis significantly improve patient engagement and decision quality. …”
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Insight into the leavening process and structural properties of buns containing okara by Caporizzi Rossella, Derossi Antonio, Speranza Barbara, Racioppo Angela, La Gatta Barbara, Rutigliano Mariacinzia, Marinaro Grazia, Di Ruzza Benedetto, Cammarelle Antonella, Viscecchia Rosaria, Corbo Maria Rosaria, Severini Carla

“…Future research should explore process optimization and sensory profiling to enhance consumer appeal and product performance.…”
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Sleep quality in patients with Parkinson’s disease in the Republic of Moldova – preliminary results by Lilia Rotaru, Madalina Cebuc, Oxana Grosu, Adrian Lupusor, Ion Moldovanu, Stela Odobescu, Svetlana Lozovanu, Victor Vovc, Ghenadie Carausu, Stanislav Groppa

“…Correspondingly, a greater interest should be applied in the establishment of prophylactic measures.…”
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Financial and legal aspects of innovation clusters by A. S. Kirpa

“…The study was carried out on the basis of general scientific interdisciplinary and specific methods (formal-legal, comparative-legal, structural-functional).…”
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STAT1β modulates the tumor immune microenvironment to improve prognosis in ovarian cancer: a comprehensive study of transcriptional and protein expression differences by Ning Lan, Xintong Li, Yifan Qiao, Siyi Zhang, Min Chen, Xiaofeng Yang, Yuliang Zou, Juan Ren, Meili Pei

“…Abstract Objectives As a central regulator of the JAK/STAT signaling pathway, STAT1 generates functionally distinct α and β protein isoforms through alternative splicing. …”
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Designing a Digital Intervention to Increase Human Milk Feeding Among Black Mothers: Qualitative Study of Acceptability and Preferences by Loral Patchen, Jeannette Tsuei, Donna Sherard, Patricia Moriarty, Zoe Mungai-Barris, Tony Ma, Elina Bajracharya, Katie Chang, William Douglas Evans

“…Third, functionality and features were identified as key factors, highlighting content diversity, ease of use, credibility, and interactivity. …”
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One more way to address the seasonal water shortage of the largest freshwater lake in China? A nature-based solution through lake bathymetry restoration by Bing Li, Guishan Yang, Rongrong Wan, David P. Hamilton, Jing Yao

“…However, trade-offs among multiple ecosystem services and an optimization procedure should be used in future to select the different opportunities for restoration planning.…”
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Ultrasonic chemical synthesis of zinc-manganese ferrites with improved magnetic properties by Wafaa Azouzi, Ikram Boulahya, Jerome Robert, Ahmed Essyed, Abdelfattah Mahmoud, Ahmed Al Shami, Dris Ihiawakrim, Hicham Labrim, Mohammed Benaissa

“…Such an ionic engineering should definitely open the way to promising applications in biomedical imaging.…”
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Revolutionizing treatment for disorders of consciousness: a multidisciplinary review of advancements in deep brain stimulation by Yi Yang, Tian-Qing Cao, Sheng-Hong He, Lu-Chen Wang, Qi-Heng He, Ling-Zhong Fan, Yong-Zhi Huang, Hao-Ran Zhang, Yong Wang, Yuan-Yuan Dang, Nan Wang, Xiao-Ke Chai, Dong Wang, Qiu-Hua Jiang, Xiao-Li Li, Chen Liu, Shou-Yan Wang

“…Despite showing promising outcomes, challenges remain in patient selection, precise target localization, and the determination of optimal stimulation parameters. Future research should focus on conducting large-scale controlled studies to delve into the pathophysiological mechanisms of DOC. …”
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Evaluation of Phenolic Compounds and Antioxidant Activity in Three Black Cherry Tomato Varieties Grown Under Greenhouse Conditions by Josué Daniel Hernández-Vega, Ixchel Parola-Contreras, Erik Gustavo Tovar-Pérez, Ramón Gerardo Guevara-González, Humberto Aguirre-Becerra, Ana Angélica Feregrino-Pérez, Luis Miguel Contreras-Medina, Rosario Guzmán-Cruz

“…These findings highlight the antioxidant potential of black cherry tomatoes and their high potential nutritional value for consumers. Future research should explore how environmental factors influence their biochemical composition and potential applications in functional food.…”
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From data on gross activity to the characterization of animal behaviour: which metrics for which purposes? by van Dixhoorn, Ingrid, Aubé, Lydiane, van Zyl, Coenraad, de Mol, Rudi, van der Werf, Joop, Lardy, Romain, Mialon, Marie-Madeleine, van Reenen, Kees, Veissier, Isabelle

“…Data processing and calculations, however, should be clarified and harmonised across studies for the results to be comparable. …”
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Effects of Ammonia Stress on Liver Tissue Structure, Enzyme Activities, and Metabolome of Juvenile Largemouth Bass <i>Micropterus salmoides</i> by Decheng Pu, Zhengxi Wang, Jishu Zheng, Peiyuan Li, Xiuli Wei, Dongsheng Li, Lihong Gao, Lin Zhou, Yu Wang

“…It is suggested that the duration of ammonia concentration exceeding 4 mg/L in high-density aquaculture should not exceed 7 days.…”
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