Who seeks treatment for gaming? Characteristics of young and adult patients seeking treatment for gaming disorder by Per Bore, Per Bore, Mitchell Andersson, Mitchell Andersson, Sara Nilsson, Kajsa Oehm, Matti Cervin, Matti Cervin, Anders Håkansson, Anders Håkansson, Emma Claesdotter-Knutsson, Emma Claesdotter-Knutsson

“…Treatment should not only address gaming behavior but also support patients in improving functioning across important areas of life, such as school, work, and relationships.…”
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Optimization of Mangiferin extraction from Mangifera Indica leaves Peruvian Criollo variation using ultrasound assisted surface response methodology by Elena Sofia Espinoza Rodríguez, Stephanie Elena Sosa Pulcha, Naysha Y. M․ Elguera, Abdel Alejandro Portocarrero Banda, Hugo Guillermo Jiménez Pacheco

“…These findings confirm that UAE is an efficient technique for extracting mangiferin while minimizing solvent use and processing time. Future studies should explore the pharmacological applications of the optimized extract and refine purification techniques to enhance its bioavailability and functional properties.…”
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Influence of semicircular canal morphology on the VOR and swimming activity in larval amphibians: a comparative study in Xenopus and axolotl by Parthena Schneider-Soupiadis, Parthena Schneider-Soupiadis, Michael Forsthofer, Michael Forsthofer, Michael Forsthofer, Felix Schneider-Soupiadis, Felix Schneider-Soupiadis, Gilles Courtand, Rosario Sanchez-Gonzalez, François M. Lambert, Hans Straka

“…This study, even preliminary, should open the pathway for further and more complete demonstrations of this functional relationship, that seems to be commonly shared during the evolution.…”
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THE NEED FOR IMPROVED METHODS OF PROSTHESIS DISTALLY UNLIMITED DEFECTS IN THE DENTITION by R. Kozak

“…The most rational structures should be considered Partial dentures, but they are not without drawbacks. …”
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Access to and challenges in water, sanitation, and hygiene in healthcare facilities during the early phase of the COVID-19 pandemic in Ethiopia: A mixed-methods evaluation. by Gete Berihun, Metadel Adane, Zebader Walle, Masresha Abebe, Yeshiwork Alemnew, Tarikuwa Natnael, Atsedemariam Andualem, Sewunet Ademe, Belachew Tegegne, Daniel Teshome, Leykun Berhanu

“…The major problems were the absence of separate latrines for healthcare workers and clients, as well as female and male staffs, an unbalanced number of functional latrines for the number of clients, non-functional latrines, poor cleanliness and misuse of the latrine. …”
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Ecosystem services and multifunctionality are co-regulated by biotic and abiotic factors along with forest types in a temperate forest of South Korea by Min-Ki Lee, Yong-Ju Lee, Jung-Hwa Chun, A-Reum Kim, Chang-Bae Lee

“…., species diversity, functional dominance, stand structural diversity) and abiotic (i.e., topography, climate, and soil) factors, and stand age on EMF and each ecosystem service category. …”
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Research on long-term outcomes of meniscectomy by G. K. Kamushadze

“…Complete or partial meniscectomy significantly increases the risk of osteoarthritis and decreases joint functionality. Preference should be given to reconstructive procedures (meniscal repair), especially in the red and red-white zones of the meniscus, which have better blood supply and regenerative potential. …”
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Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…Discussion Medium-dose inhaled corticosteroid + long-acting β2-agonist is recommended for children with asthma that is uncontrolled on inhaled corticosteroid alone; leukotriene receptor antagonist alone should be avoided. We could not include data from 67% of the eligible trials, conclusions should therefore be viewed with some caution. …”
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Coeliac Disease and Connection with Iron Deficiency Anemia: A Literature Review by Aleksandra Zielińska, Szymon Szypulski, Kinga Kowalik, Maria Michalska, Kinga Tylczyńska, Jakub Skiba, Sebastian Iwaniuk, Ignacy Maciejewski, Natalia Tylczyńska, Zuzanna Skiba

“…There are many causes of iron deficiency anemia (IDA), but celiac disease should always be considered as one of them. The immune response to gluten proteins is the underlying mechanism of the disease. …”
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Effects of reservoir regulation on downstream benthic invertebrate drift in dammed rivers: A review by Jiaxuan Tang, Qin Yang, Qinghui Zeng, Peng Hu, Long Yan, Baolong Zhao, Fengbo Zhang, Kang Zhao, Jinliang Zhang

“…Based on these processes, we suggest that future field sampling research on benthic invertebrate drift should be expanded to include Asian and high-altitude large regulated rivers. …”
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Smartphone Application‐Based Addiction Scale: Psychometric Evidence Across Nine Asian Regions Using Advanced Analytic Methods by I‐Hua Chen, Iqbal Pramukti, Wan Ying Gan, Kamolthip Ruckwongpatr, Le An Pham, Po‐Ching Huang, Mohammed A. Mamun, Irfan Ullah, Haitham A. Jahrami, Chung‐Ying Lin, Amir H. Pakpour

“…ABSTRACT Introduction A smartphone is a device with various functions, including wifi, application functions, mobile networks, ease of mobility, and the capability of using mobile data. …”
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Craniofacial Fibrous Dysplasia: Surgical Management and Long-Term Outcomes at a Referral Center in Mexico City by Luis Alejandro Lopez-Garibay, Osvaldo Guevara-Valmaña, Jose Eduardo Telich-Tarriba, David Felipe Navarro-Barquín, Natalia Haro-Alvarez, Laura Andrade-Delgado, Rogelio Martínez-Wagner

“…An adequate clinical characterization considering the number of affected bones and functional impairment is important to determine the most effective surgical intervention for its management. …”
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Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics by Kristian Galanti, Ghaith Sharaf Dabbagh, Fabrizio Ricci, Sabina Gallina, Roberta Giansante, Ron Jacob, Edmond Obeng‐Gyimah, Leslie T. Cooper Jr, Sanjay K. Prasad, David H. Birnie, Andrew P. Landstrom, Selma F. Mohammed, Saidi Mohiddin, Mohammed Y. Khanji, Anwar A. Chahal

“…A multimodal non‐invasive imaging approach is essential for accurate morpho‐functional assessment of cardiac chambers and is key to establish the cardiac phenotype and to rule out an underlying ischaemic aetiology. …”
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Parents’ perceptions of core outcomes in neonatal research in two Nigerian neonatal units by Ian Sinha, Melissa Gladstone, Janneke van de Wijgert, Kevin Mortimer, Sarah Kathryn Read, Aisha Jibril, Olukemi Tongo, Abimbole Akindolire, Isa Abdulkadir, Helen Nabwera, Stephen Allen, Olusegun Akinyinka, Dominic Umoru, Chinyere Ezeaka, Ireti Fajolu, Beatrice Ezenwa, Zainab Imam, Martha Mwangome, Alison Talbert, Pauline Andang’o, Walter Otieno, Grace Nalwa, Graham Devereux, Ismaela Abubakar, Nicholas Embleton

“…Further research should assess the opinions of families in other low-resource settings and also engage a broader range of stakeholders.…”
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Neurobiological and Microbiota Alterations After Bariatric Surgery: Implications for Hunger, Appetite, Taste, and Long-Term Metabolic Health by Sebastián Chapela, Ludwig Alvarez-Córdova, Andres Martinuzzi, Rosario Suarez, Victoria Gonzalez, Ezequiel Manrique, Janeth Castaño, Gianluca Rossetti, Luigi Cobellis, Vincenzo Pilone, Evelyn Frias-Toral, Luigi Schiavo

“…Neuroimaging studies reveal structural and functional changes in brain regions involved in reward processing and cognitive control, contributing to reduced cravings and altered food choices. …”
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Plasticity in activity patterns of ungulates under the influence of shade coffee agricultural intensification in Ethiopia by Behailu Etana, Peter J. Fashing, Anagaw Atickem, Afework Bekele, Nils Chr. Stenseth

“…Several ungulates play a crucial role in maintaining forest functions and are vulnerable to disturbances caused by humans. …”
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A Rare Cause of Hypergonadotropic Hypogonadism: Transaldolase Deficiency in Two Siblings by Melek Yıldız, Zerrin Önal, Gözde Yeşil, Tuğçe Göksu Kabil, Güven Toksoy, Şükran Poyrazoğlu, Firdevs Baş, Özlem Durmaz, Feyza Darendeliler

“…The diagnosis of transaldolase deficiency should be kept in mind for these patients, and they must be evaluated for gonadal functions, especially during puberty.…”
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FtsZ as a novel target for antibiotics development: Promises and challenges by Ming-Wei Wang, Kaini Hang, Wei Han, Xin Li, Qingtong Zhou, Dehua Yang

“…However, clinical translation is hindered by weak binding affinities, inhibitory inefficacy, dynamic conformational flexibility, and evolving drug resistance linked to FtsZ's functional plasticity. To address these challenges, future efforts should be directed to resolve transient assembly intermediates, leveraging machine learning with high-throughput screening, and integrating structural biology with pharmacokinetic optimization. …”
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Berries anthocyanins as potential SARS-CoV–2 inhibitors targeting the viral attachment and replication; molecular docking simulation by Omar Messaoudi, Hicham Gouzi, Abdelaziz Nasr El-Hoshoudy, Farouk Benaceur, Chirag Patel, Dweipayan Goswami, Djoudi Boukerouis, Mourad Bendahou

“…Considering the obtained results, regular consumption of berry fruits, which are rich in anthocyanin compounds, should be supportive to inhibit viral infectious by reducing of propagation and pathogenicity of SARS-CoV–2.…”
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GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery by Loes van Schie, Wander Van Breedam, Charlotte Roels, Bert Schepens, Martin Frank, Ahmad Reza Mehdipour, Bram Laukens, Wim Nerinckx, Francis Santens, Simon Devos, Iebe Rossey, Karel Thooft, Sandrine Vanmarcke, Annelies Van Hecke, Xavier Saelens, Nico Callewaert

“…To further increase the versatility of VHHs, we explored the VHH scaffold in a structure-guided approach to select regions where the introduction of an N-glycosylation N-X-T sequon and its associated glycan should not interfere with protein folding or epitope recognition. …”
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