Product Development Study of Freeze-Dried Apples Enriched with Sea Buckthorn Juice and Calcium Lactate by Marcellus Arnold, Wojciech Białas, Bartosz Kulczyński, Ribi Ramadanti Multisona, Joanna Suliburska, Michał Świeca, Aneta Wojdyło, Anna Gramza-Michałowska

“…Enriched or fortified foods are typically linked to ultra-processed foods, limiting the choice of functional food in the market. Addressing the market potential, particularly the elder population with osteoporosis, the functional food industry should consider developing a healthy snack enriched with bioactive substances. …”
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Artificial intelligence-assisted RNA-binding protein signature for prognostic stratification and therapeutic guidance in breast cancer by Yunxia Zhao, Li Li, Shuqi Yuan, Zixin Meng, Jiayi Xu, Zhaogen Cai, Yijing Zhang, Xiaonan Zhang, Tao Wang

“…It provides actionable insights for personalized therapy, paving the way for improved clinical outcomes. Future studies should validate findings across diverse populations and expand functional analyses.…”
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Exploring dual-coating strategies for probiotic microencapsulation using polysaccharide and protein systems by Phin Yin Sin, Suat Hian Tan, Mohd Fazli Farida Asras, Chin Mei Lee, Thong Chuan Lee, Md. Rezaul Karim, Nyuk Ling Ma

“…These synergistic interactions significantly improve probiotic viability and functionality under extreme conditions. This review examines the mechanisms, benefits, and challenges of dual-coating strategies. …”
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Insurance Payor Status and Outcomes in Pediatric Sports-Related Injuries: A Rapid Review by Katherine M. Kutzer, Lulla V. Kiwinda, Daniel Yang, John Kyle Mitchell, Emily J. Luo, Emily J. Harman, Stephanie Hendren, Kendall E. Bradley, Brian C. Lau

“…Outcomes included time to be seen by a provider, treatment access, complication and revision rates, postoperative Emergency Department (ED)/Urgent Care utilization, readmission rates, hospital length of stay, pain, functional scores, discharge destinations, return to activity, and follow-up. …”
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Performance of multiscale landscape metrics as indicators of soil C, N, P, and physicochemical properties of NFV in ML reaches of Yellow River Basin, China by Chenhui Wei, Kaili Chen, Zhan Yang, Siqi Yao, Chen He, Lin Zhang

“…Landscape metrics are significant indicators of ecological functions. However, limited data are available regarding the relationship between landscape metrics and soil ecological functions. …”
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The DRP1 receptor FIS1 is critical to the expansion of triple-negative breast cancer tumor-initiating cells by Tetiana Katrii, Tanya Freywald, Malkon G. Estrada, Amr El Zawily, Behzad Toosi, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, Andrew Freywald, Scot C. Leary

“…Conclusion Our data collectively suggest that FIS1 targeting should allow for the suppression of TICs in TNBC tumors without compromising mitochondrial functionality or causing major, systemic toxicity. …”
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Analgesic and Neuroprotective Roles of Dexmedetomidine in Spine Surgery: A Systematic Review by Spyridoula Roberta Afrati, Ioanna Lianou, Angelos Kaspiris, Vasileios Marougklianis, Anastasia Kotanidou, Spiros G. Pneumaticos

“…Although many studies displayed the effectiveness of DEX in postoperative pain management, the impact of DEX on functional improvement after spinal surgeries is still debatable. …”
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Clinical Case of Echinococcosis of the Orbit. Modern Approaches to Diagnosis and Treatment by D. S. Gorbachev, A. N. Kulikov, S. S. Kozlov, A. A. Kolbin, A. V. Voronov, A. V. Kudryavtseva, I. S. Kovalevskaya, A. I. Yakovenko, M. A. Burnasheva, N. N. Haritonova, N. V. Zemlyanukhin

“…It is noted that the duration of antiparasitic therapy should be determined in each case individually.…”
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A Method for Assessing the Severity of Obstructive Jaundice of Non-Neoplastic Origin by A. P. Vlasov, N. S. Sheyranov, O. V. Markin, T. I. Vlasova, T. A. Muratova, V. E. Ryazantsev, D. E. Timoshkin, K. M. Sinyavina, A. V. Kolesov

“…AIM OF STUDY To develop a method for assessing the severity of obstructive jaundice (OJ) of non-neoplastic orogin on the basis of functional parameters of the liver and the activity of pathogenetic agents of hepatodepression.MATERIAL AND METHODS Clinical and laboratory studies of 142 patients with breast cancer of non-tumor origin. …”
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The human STING agonist E7766 induces immunogenic tumor clearance, independent of tumor-intrinsic STING expression in the KRASG12D/+ Trp53−/− murine model of sarcoma by Karys M. Hildebrand, Kurt N. Hildebrand, Carolina Salazar Arcila, Kayla Marritt, Jahanara Rajwani, Golpira Elmi Assadzadeh, Antoine Dufour, Frank R. Jirik, Michael J. Monument

“…Using STING deficient mice, and CRISPR/Cas9 gene editing, we demonstrated that STS clearance following STING therapy was dependent on host STING and not tumor-intrinsic STING pathway functionality. E7766 represents a promising candidate able to remodel the TME of murine STS tumors toward an inflamed phenotype independent of tumor-intrinsic STING functionality, and should be considered for potential translation in STS treatment.…”
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Legal regulation of the system of public administration entities providing the administrative and legal regime of special economic zones by O. A. Lakaev

“…Rules on the special economic zones administration should be set out in a chapter entitled “Peculiarities of Implementation public authorities in special economic zones”. …”
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Advances in KEAP1-based PROTACs as emerging therapeutic modalities: Structural basis and progress by Jing Chen, Disheng Feng, Rui Zhu, Hua Li, Lixia Chen

“…Kelch-like ECH-associated protein 1 (KEAP1) functions as a substrate adaptor for the Cullin 3-RING E3 ligase complex, mediating the ubiquitination and subsequent proteasomal degradation of nuclear factor erythroid 2-related factor 2 (NRF2). …”
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Mobile-Based Women’s Sexual Health Education Application: Providing a Content Model by Maryam Jahanbakhsh, Mahnaz Noroozi, Majid Jangi, Fateme Ghadiri Kofrani

“…Background and Aim: Education on sexually transmitted diseases and functional disorders in Iranian women’s society are two important issues that should be addressed as aspects of sexual health. …”
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From fixing to connecting—developing mutual empathy guided through movement as a novel path for the discovery of better outcomes in autism by Anat Baniel, Eilat Almagor, Neil Sharp, Ohad Kolumbus, Martha R. Herbert, Martha R. Herbert

“…These methods should enable refinement and scalability of tracking and assessing the mechanisms and effectiveness of the interventions.…”
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Screening of Nutritionally Important Components in Standard and Ancient Cereals by Vesna Dragičević, Milena Simić, Vesna Kandić Raftery, Jelena Vukadinović, Margarita Dodevska, Sanja Đurović, Milan Brankov

“…Sustainable nutrition and food production involve dietary habits and farming systems which are eco-friendly, created to provide highly nutritious staple crops which could serve as a functional food at the same time. This research sought to provide a comprehensive analysis of whole-grain cereals, and some ancient grains toward important macro- (protein), micro-nutrients (mineral elements), and bioactive compounds, such as dietary fiber (arabinoxylan and β-glucan) and antioxidants (phytic acid, total glutathione, yellow pigment, and phenolic compounds) to provide functionality in a sustainable diet. …”
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LABORATORY STUDY OF POLYMERIZATION DEPTH OF COMPOSITE MATERIALS by O.A. Udod, Kh.I. Bekuzarova

“…All these allows restoring the anatomical shape of teeth and functional characteristics even with a significant degree of damage. …”
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Microbiome matters: how transplantation methods and donor origins shape the successful restoration of the seagrass Posidonia oceanica by Arnaud Boulenger, Tânia Aires, Aschwin H. Engelen, Gerard Muyzer, Michel Marengo, Sylvie Gobert

“…These results imply that restoration strategies should prioritize methods enhancing sediment–root interactions to support microbial recovery. …”
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Spatiotemporal Variation and Driving Mechanisms of Carbon Budgets in Territorial Space for Typical Lake-Intensive Regions in China: A Case Study of the Dongting Lake Region by Suwen Xiong, Zhenni Xu, Fan Yang, Chuntian Gu

“…However, methods for measuring territorial space carbon budgets tailored to “production–living–ecological” functions are underdeveloped, and the mechanisms driving carbon imbalance risks remain unclear. …”
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Improving the efficiency of the formation of professional competencies Masters in “Information Security” based on the use o CASE-technologies by A. V. Gavrilov, V. A. Sizov

“…For the formation of the register of enterprise information resources, it is proposed to build a structural-functional enterprise model using the IDEF0 notation. …”
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Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease by Fabiana Sassone, Catherine Estay-Ahumada, Michel J. Roux, Dominique Ciocca, Paola Rossolillo, Marie-Christine Birling, Janet R. Sparrow, Diego Montenegro, David Hicks

“…Non-invasive fundus imaging showed widespread photoreceptor loss, confirmed by ocular coherence tomography. Functional recording by single flash and flicker electroretinography showed significant decline in photopic (cone) light responses. …”
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