In-depth insight into tumor-infiltrating stromal cells linked to tertiary lymphoid structures and their prospective function in cancer immunotherapy by Maedeh Radandish, Niloofar Mashhadi, Amir Hossein Aghayan, Motahareh Taghizadeh, Sara Salehianfard, Sheida Yahyazadeh, Omid Vakili, Somayeh Igder

“…Furthermore, it highlights the dual functional roles of TLSs as sites of both anti-tumor immune activation and immunosuppression, notably via the enrichment of regulatory T cells. …”
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A comparison of three methods in categorizing functional status to predict hospital readmission across post-acute care. by Chih-Ying Li, Amol Karmarkar, Yong-Fang Kuo, Hemalkumar B Mehta, Trudy Mallinson, Allen Haas, Amit Kumar, Kenneth J Ottenbacher

“…To facilitate clinical and scientific use, we suggest the most appropriate method to categorize functional status should be based on the strengths and weaknesses of each method.…”
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AGREE: an upper limb motorized exoskeleton for restoring arm functions: a single-blinded randomized controlled trial by Marta Gandolla, Beatrice Luciani, Valeria Longatelli, Peppino Tropea, Agnese Seregni, Massimo Corbo, Francesco Braghin, Alessandra Pedrocchi

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The Contractile Function of Ventricular Cardiomyocytes Is More Sensitive to Acute 17β-Estradiol Treatment Compared to Atrial Cardiomyocytes by Tatiana A. Myachina, Xenia A. Butova, Raisa A. Simonova, Denis A. Volzhaninov, Anastasia M. Kochurova, Galina V. Kopylova, Daniil V. Shchepkin, Anastasia D. Khokhlova

“…Here we found a chamber specificity of myocardial contractile function to E2 that should be taken into account for the potential side effects of HRT.…”
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A Black Sticky Rice-Derived Functional Ingredient Improves Anxiety, Depression, and Stress Perception in Adult Volunteers by Pattamaporn Natthee, Jintanaporn Wattanathorn, Wipawee Thukham-mee, Pongsatorn Paholpak, Poonsri Rangseekajee, Nawanant Piyavhatkul, Suphayanakorn Wattanathorn, Supaporn Muchimapura, Terdthai Tong-Un

“…Our results show that the novel functional ingredient can improve anxiety, depression, and stress perception partly by decreasing oxidative stress and inflammation; however, randomized, double-blind, placebo-controlled studies with a larger sample size should be performed to confirm this benefit.…”
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Clinical and instrument-based assessment of balance, gait, and motor functions in pediatric cerebral palsy: A systematic review by Dilnoza Karibzhanova, Prashant K. Jamwal, Amna Riaz Khawaja, Zaidagul Kystaubayeva, Akim Kapsalyamov, Meiram Shakenov, Sunil Agrawal

“…Given the diversity in assessment needs – whether evaluating dynamic, functional, or static balance – there is a need to identify the most suitable tools for each aspect. …”
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A Copula Function–Monte Carlo Method-Based Assessment of the Risk of Agricultural Water Demand in Xinjiang, China by Xianli Wang, Zhigang Zhao, Feilong Jie, Jingjing Xu, Sheng Li, Kun Hao, Youliang Peng

“…This study employs the copula function (CF) and Monte Carlo (MC) methods to evaluate agricultural water demand risk at 66 stations in Xinjiang. …”
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From Waste to Resource: Nutritional and Functional Potential of Borlotto Bean Pods (<i>Phaseolus vulgaris</i> L.) by Antonella Smeriglio, Martina Imbesi, Mariarosaria Ingegneri, Rossana Rando, Manuela Mandrone, Ilaria Chiocchio, Ferruccio Poli, Domenico Trombetta

“…These results highlight the potential of borlotto bean pods as a sustainable source of nutritionally and functionally relevant compounds. Future studies should focus on the bioavailability of active constituents, formulation into delivery systems, and in vivo validation to support potential nutraceutical applications.…”
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Exploiting Microperimetry as a Functional End Point in Healthy Aging and Different Stages of Age-Related Macular Degeneration by Johannes Schrittwieser, MD, Klaudia Birner, MD, Leonard M. Coulibaly, MD, Ursula Schmidt-Erfurth, MD, Gregor S. Reiter, MD, PhD

“…Objective: To compare functional parameters between healthy aged eyes and different stages of age-related macular degeneration (AMD) based on functional parameters in microperimetry (MP) in 2 commonly used MP devices. …”
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Effects of functional training on physical and technical performance among the athletic population: a systematic review and narrative synthesis by Wensheng Xiao, Te Bu, Junlong Zhang, Haogang Cai, Wuyi Zhu, Xiaorong Bai, Lin Zhang, Soh Kim Geok

“…Therefore, future studies should focus on the physical and technical performance of different sports groups with different types and durations of functional training programs to expand the current evidence base.…”
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Forest restoration and biodiversity enhancement across China: Regional case insights into ecosystem function recovery and conservation outcomes by Peng Zhang, Lixiao Ni, Hind Alofaysan, Mammadova Simuzar Sultan, Norboy Karimov

“…Freshwater ecosystems are increasingly subjected to multiple anthropogenic stressors, notably pesticide contamination and nutrient enrichment, which jointly threaten biodiversity and impair key ecosystem functions. This study conducts a comprehensive ecological risk assessment to evaluate the interactive effects of these stressors on freshwater biodiversity and ecological processes across diverse aquatic systems in China. …”
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Effects of hemodilution on coagulation function during prolonged hypotensive resuscitation in a porcine model of severe hemorrhagic shock by Clifford G Morgan, Leslie E Neidert, Emily N Hathaway, Sylvain Cardin, Jacob J Glaser, Peter J Hemond, Michael M Tiller

“…Future studies should address therapeutics that can mitigate potential hemodilutional effects such as lack of fibrinogen or platelets.Level of evidence Not applicable—Basic Animal Research.…”
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Bridging Science and Lifestyle: A Feasibility Study for Developing a Novel Functional Food to Support Well-Being by Efstratios Christodoulou, Sotiria Laoutari, Fani Athanasiou, Eleni Poutli, Demetriana Andreou, Yiannis Kourkoutas, Antonios E. Koutelidakis

“…This research also examines consumer preferences to identify key characteristics that novel functional foods designed to enhance mental well-being should possess. …”
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Neural mechanisms of spatial navigation in ASD and TD children: insights from EEG microstate and functional connectivity analysis by Yao Wang, Yao Wang, Yao Wang, Jianing Wang, Chong Lu, Chong Lu, Chong Lu, Chong Lu, Chong Lu

“…EEG microstates and functional connectivity (FC) are useful tools for investigating these differences. …”
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Clinical Characteristics and Potential Mechanisms in Patients with Abnormal Liver Function Indices and Elevated Serum IgG4 by Jing Wang, Yue Zhang, Dandan Jiang, Lu Zhou, Bangmao Wang

“…Glucocorticoid therapy is effective in patients with abnormal liver function indices and IgG4-related disease. Assessing immune function in patients with abnormal liver function indices and elevated serum IgG4 levels should facilitate diagnosis and treatment of the disease.…”
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Enhancing bioactive profiles of elderberry juice through yeast fermentation: a pathway to low-sugar functional beverages by Amir Shazad, Ali Zein Alabiden Tlais, Davide Gottardi, Pasquale Filannino, Francesca Patrignani, Rosalba Lanciotti, Marco Gobbetti, Raffaella Di Cagno

“…In response to the growing need for functional beverages, this study aimed to harness yeast metabolism to optimize elderberry juice fermentation, targeting sugar reduction and enrichment of bioactive compounds with enhanced functional properties. …”
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Impact of Polystyrene Microplastics on Human Sperm Functionality: An In Vitro Study of Cytotoxicity, Genotoxicity and Fertility-Related Genes Expression by Filomena Mottola, Maria Carannante, Ilaria Palmieri, Lorenzo Ibello, Luigi Montano, Mariaceleste Pezzullo, Nicola Mosca, Nicoletta Potenza, Lucia Rocco

“…Possible environmental and working exposure to pollutants should be considered during the counselling for male infertility.…”
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Assessing mesh size and diffusion of alginate bioinks: A crucial factor for successful bioprinting functional pancreatic islets by Carolin Hermanns, Rick H.W. de Vries, Timo Rademakers, Adam Stell, Denise F.A. de Bont, Omar Paulino da Silva Filho, Marlon J. Jetten, Carlos D. Mota, Sami G. Mohammed, Vijayaganapathy Vaithilingam, Aart A. van Apeldoorn

“…A crucial factor in selecting a cell compatible bioink, that maintains islet functionality, is the mesh size and diffusion capacity of the bioink. …”
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Association between insecticide exposomics and cognitive function in older adults: an observational study based on NHANES 2011–2014 by Mengfan Zhang, Xiaofang Guo, Yuanjun Chen, Xinghua Liu, Xingdong Lin

“…ObjectiveThis study aims to investigate the association between exposure to insecticide exposomics and cognitive function, among adults aged 60 and above.MethodsWe employed a multi-stage probability sampling method to analyze data derived from the National Health and Nutrition Examination Survey (NHANES) conducted between 2011 and 2014. …”
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Effect of dapagliflozin on the structural and functional properties of arterial vessels in patients with type 2 diabetes mellitus in combination with obesity by О. А. Soloviuk, R. L. Kulynych

“…Modern trends in the treatment of type 2 diabetes mellitus (DM) should include not only the normalization of carbohydrate metabolism disorders, but also a possible positive effect on the cardiovascular system. …”
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