Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. by Soumya Raychaudhuri, Joshua M Korn, Steven A McCarroll, International Schizophrenia Consortium, David Altshuler, Pamela Sklar, Shaun Purcell, Mark J Daly

“…One hypothesis is that CNV events cause disease by affecting genes with specific brain functions. Under these circumstances, we expect that CNV events in cases should impact brain-function genes more frequently than those events in controls. …”
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Partnership delivery of evidence-based therapy intervention to improve upper-limb function: a retrospective analysis by Anne Gordon, Erika Molteni, Tomoki Arichi, Jill Massey, Ben Siegle, Leanne Dreyer

“…Of caregivers surveyed, 97.85% would repeat the programme, and 100% would recommend it to others.Conclusions Evelina REACH is a clinically effective, goal-directed intensive activity-based therapy intervention that fosters lasting functional improvements in upper-limb use. Further research should explore optimal and scalable co-delivery models to enhance children’s access to evidence-based therapy in statutory healthcare.…”
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Randomized Control Trial Comparing Effects of Tourniquets on Neurology and Functional Outcomes after Total Knee Arthoplasty by Gur-Aziz Singh Sidhu, Saphalya Pattnaik, Mothana Gawad, Rafia Ghani, Harjot Kaur, Neil Ashwood

“…The literature reveals a divided opinion on whether TKA should be performed with or without a tourniquet, with conflicting results on post-operative pain, blood loss, and functional outcomes.. …”
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Dispersal mode mediates the seed functional traits of woody plants’ responses to urbanization in remnant forest patches by Minglu Guo, Zijin Wang, Yanjun Zheng, Ying Pan, Jingyi Yang

“…This study focuses on the impacts of urbanization on woody plants in Guiyang, China, emphasizing seed functional traits to understand plant adaptive strategies and support urban biodiversity conservation. …”
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Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease by Steven Ness, Konstantina Sampani, Fatima Tuz-Zahra, Nurgul Aytan, Sreevardhan Alluri, Marissa G. Fiorello, Xuejing Chen, Nicole H. Siegel, Michael L. Alosco, Weiming Xia, Yorghos Tripodis, Thor D. Stein, Manju L. Subramanian

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A Detailed Anatomical Description of the Gastrocnemius Muscle—Is It Anatomically Positioned to Function as an Antagonist to the Anterior Cruciate Ligament? by Kevin Thomas, Jason Peeler

“…Our data clearly illustrate that the femoral attachment of the medial head of the gastrocnemius was much different (or more complex) than previously described and that it wraps around the posterior side of the medial femoral condyle and attaches more anteriorly. Further research should be directed at exploring the functional significance (if any) of these differences and examining the effect they may have on ACL function and knee joint kinematics.…”
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A Pilot Study on the Influence of Diaphragmatic Function on Iliopsoas Muscle Activity in Individuals with Chronic Ankle Instability by Takumi Jiroumaru, Shun Nomura, Yutaro Hyodo, Michio Wachi, Junko Ochi, Nobuko Shichiri, Takamitsu Fujikawa

“…This study highlights the association between reduced iliopsoas activity during end-inspiration and compromised diaphragmatic function in patients with CAI. Future research should explore dynamic movement tasks and larger sample sizes to elucidate neuromuscular mechanisms further and refine rehabilitation strategies.…”
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Spatial Patterns and Functioning of Water Springs in the Sacred Landscape Structure: The Case of Lviv and Volyn Oblasts of Ukraine by Olena Mishchenko, Valerii Petlin, Serhii Puhach

“… Sacred springs are significant among water sources, as they serve not only natural functions but also social ones, fulfilling the spiritual needs of residents and pilgrims. …”
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The Relationship Between Social Participation and Cognitive Function in Older Adults: The Mediating Role of Activities of Daily Living by Chong Zhang, Juan Xiong, Wenqi Luo, Lin Sun

“…Families can organize regular activities, communities create self-entertainment programs, and healthcare providers integrate social activities into geriatric care. Future studies should explore additional confounding factors and use more comprehensive measures of social participation to better capture its impact on cognitive function.…”
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Comparison of Postural and Functional Indicators in Adolescent Boys with and Without Non-specific Chronic Low Back Pain by moein yari bishak, Ebrahim mohammad ali nasab firouzjah, Mehri Mohammadi Dangraloo

“…This study aimed to compare specific postural and functional indicators in adolescent boys with and without non-specific chronic low back pain. …”
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Decreased β-cell function in a case with Becker muscular dystrophy accompanied by post-transplant diabetes by Kazuya Motohashi, Takaaki Murakami, Daisuke Otani, Toshihiro Nakamura, Takao Kato, Osamu Seguchi, Masahito Ogura, Daisuke Yabe, Nobuya Inagaki

“…Although he did not show evident glucose intolerance before heart transplantation, he demonstrated decreased β-cell function. Despite the shared background of BMD, his older brother, who had not undergone heart transplantation, showed only slightly impaired glucose tolerance and preserved β-cell function. …”
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Significantly Decreased Islet β Cell Function is Closely Associated with Hyperglycemia in Chronic Hepatitis B Patients by Dafeng Liu, Lingyun Zhou, Xinyi Zhang, Yilan Zeng, Lang Bai, Dongbo Wu, Hong Tang

“…Further research should be done to verify the compromised islet β cell function and then to investigate the mechanisms behind the effect of hepatitis B virus infection on islet β cell function in CHB patients.…”
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Assessment of the Short-Term Effectiveness of Kinesiotaping and Trigger Points Release Used in Functional Disorders of the Masticatory Muscles by Danuta Lietz-Kijak, Łukasz Kopacz, Roman Ardan, Marta Grzegocka, Edward Kijak

“…Because hidden trigger points can spontaneously activate, they should be found and released to prevent further escalation of the discomfort. …”
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Functional recovery after lumbar spinal stenosis surgery: Postural balance and residual urine as objective markers by Andreas K. Andresen, Leah Y. Carreon, Mikkel Østerheden Andersen

“…Discussion and conclusion: Postural balance and post void residual urine, along with patient reported outcome measures, improved shortly after surgery, and the improvement was sustained two years after surgery. Physicians should consider using these two functional objective measures to evaluate disease severity and treatment effectiveness in patients with lumbar spinal stenosis.…”
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Positional Differences in Youth Water Polo Players: Cognitive Functions, Specific Swimming Capacities and Anthropometric Characteristics by Neven Kovačević, Frane Mihanović, Linda Lušić Kalcina, Tatjana Matijaš, Tea Galić

“…These recommendations should take into account anthropometric characteristics, specific functional swimming capacities and cognitive functions that influence players’ game intelligence, which can be enhanced through properly designed training programs.…”
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The mediating role of step counts in the relationship between diverse neighbourhood destinations and older adults’ physical function by Chien-Yu Lin, Hsin-Yen Yen, Ming-Chun Hsueh, Jong-Hwan Park, Yung Liao

“…These findings suggest strategic allocation of neighbourhood resources, such as parks, to promote walking behaviour and enhance physical functioning in older adults. Future research should explore park design, usage patterns, and other potential mediators related to public transport stations to refine strategies for maintaining and improving physical functioning in ageing populations.…”
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Intra-abdominal pressure and residual renal function decline in peritoneal dialysis: a threshold-based investigation by Jingjing Zhang, Lei Song, Zhongwei Ma, Lina Sun, Xiaoqing Wang, Duanyan Liu, Feng Huang, Yulin Man

“…IAP, as one of the factors contributing to the rapid decline in RRF in the first year of PD, should be given due attention.…”
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THE IMPACT OF THIRD-GENERATION BETA-BLOCKER ANTIHYPERTENSIVE TREATMENT ON ENDOTHELIAL FUNCTION AND THE PROTHROMBOTIC STATUS. EFFECTS OF SMOKING by G. P. Vyssoulis, A. G. Marinakis, K. A. Aznaouridis, E. A. Karpanou, A. N. Arapogianni, D. V. Cokkinos, C. I. Stefanadis

“…The effect of vasodilating β-blockers on endothelial function and prothrombotic state has not been investigated. …”
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Spatial and Temporal Changes and Prediction of Habitat Quality in Key Ecological Function Area of Hu'nan Province by Zheng Yunyou, Liu Yanting, Yao Peng, Xie Xianjun, Zhang Guangjie, Deng Chuxiong

“…Therefore, resource and environment control should be strengthened in Nanyue key ecological function zones.…”
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Assessment of endothelial function and arterial rigidity in patients with type 1 diabetes at different stages of diabetic nephropathy by Evgenia Pavlovna Kosobyan, Ivona Renata Yarek-Martynova, Alexander Sergeevich Parfenov, Lyubov' Leonidovna Bolotskaya, Marina Vladimirovna Shestakova

“…Assessment of vascular stiffness and endothelial function in patients with type 1 diabetes at different stages of diabetic nephropathy and without it. …”
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