Obstructive hypertrophic cardiomyopathy: from genetic insights to a multimodal therapeutic approach with mavacamten, aficamten, and beyond by Khadija Sarwer, Saeeda Lashari, Nida Rafaqat, Maher, Abdul Raheem, Muneeb Ur Rehman, Syed Muhammad Iraj Abbas

“…These mutations lead to disrupted sarcomere function, resulting in hypertrophic changes and LVOT obstruction. …”
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MODALITY AND PERSUASION IN ADVERTISING: THE TRANSLATION ASPECT by Natalia I. Talan

“…Advertising performs several main functions, including the following ones: the central function – is the function of influence and also important communicative functions, which are divided into primary: communicative, regulatory and generalizing ones, and secondary: emotional, aesthetic, contact ones. …”
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A preliminary estimate of the environmental burden of disease associated with exposure to pyrethroid insecticides and ADHD in Europe based on human biomonitoring by Anthony Purece, Sofie Theresa Thomsen, Dietrich Plass, Anastasia Spyropoulou, Kyriaki Machera, Philippe Palmont, Amélie Crépet, Rafiqa Benchrih, Brecht Devleesschauwer, Nina Wieland, Paul Scheepers, Deepika Deepika, Vikas Kumar, Gerardo Sanchez, Jos Bessems, Dario Piselli, Jurgen Buekers

“…A sensitivity analysis showed that by applying a different exposure-response function from outside the EU, the population attributable fraction decreased from an average of 18 to 7%. …”
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Development of Sub-channel Program and Multi-objective Optimization Method Research for Printed Circuit Heat Exchanger by CHEN Liqin, HUO Honglei, XIE Renyao, YANG Yi

“…Taking it as the objective function, the purpose of the research is to optimize the regenerator from multiple dimensions. …”
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Surgical vs. non-surgical management of cervical spine fractures associated with ankylosing spinal disorders: a matched retrospective comparison assessing mortality by Josefin Åkerstedt, Ali Buwaider, Victor Gabriel El-Hajj, Johan Wänman, Henrik Frisk, Simon Blixt, Anna MacDowall, Erik Edström, Adrian Elmi-Terander, Anastasios Charalampidis

“…Preoperative variables included age, sex, trauma type, neurological function, fracture morphology, and treatment method. …”
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Which outcomes are key to the pre-intervention assessment profile of a child with developmental coordination disorder? A systematic review and meta-analysis by Bouwien Smits-Engelsman, Marisja Denysschen, Jessica Lust, Dané Coetzee, Ludvík Valtr, Marina Schoemaker, Evi Verbecque

“…Background: Purpose of this study was to determine what key aspects of function should be incorporated to make up a pre-intervention assessment profile of a child with Developmental Coordination Disorder (DCD); more specifically, what aspects of functioning are implicated in DCD and what is their relative impact? …”
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Differences in Soil Reinforcement and Root Fatigue Properties of Typical Shrubs in Semi-arid Mining Areas by Xin Zhang, Bo Wang, Tiejun Liu, Jianying Guo, Hugang Wang, Zhenqi Yang

“…The cumulative root length and root surface area were mostly concentrated in the 10-20 cm shallow soil, with proportions of 30.1% and 29.8%, respectively. ② The tensile force of the taproots of the three shrubs before and after fatigue was positively correlated with root diameter by a power function relationship, and a negative power function relationship between tensile strength and root diameter was observed. …”
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Medications for Hypertension Change the Secretome Profile from Marrow Stromal Cells and Peripheral Blood Monocytes by Nikunj Satani, Kaavya Giridhar, Chunyan Cai, Natalia Wewior, Dominique D. Norris, Jaroslaw Aronowski, Sean I. Savitz

“…MSCs are proposed to promote recovery through the release of secretomes that modulate the function of beneficial immune cells. The majority of stroke patients have comorbidities including hypertension, for which they are prescribed antihypertensive medications that might affect the function of MSCs, when they are administered in stroke patients. …”
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Delayed diagnosis of the full triad autoimmune polyendocrine syndrome type 2 with adrenal crisis: a case report and literature review by Zihong Yao, Zihong Yao, Hui Chen, Xuejian Hu, Dan Ge, Xiangyu Xu, Danxia Xu

“…Thyroxine replacement therapy and potential TCM-induced changes may have aggravated cortisol metabolism and immune imbalances, hastening adrenal failure. Clinicians should implement stepwise organ-function monitoring in patients with any single-gland autoimmune disease, maintain vigilance for exogenous medication use, and implement multidisciplinary management strategies to mitigate the risk of AC. …”
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Cognitive-motor dual-task training on gait and balance in stroke patients: meta-analytic report and trial sequential analysis of randomized clinical trials by Lu Zhang, Jiangping Ma, Xiaoqing Liu, Aiping Jin, Kai Wang, Xiaobing Yin

“…Conclusion Cognitive-motor dual-task training (CMDT) compared with conventional physical single-task training might be an effective intervention for improving static balance function in stroke patients (low-quality evidence), which should be interpreted cautiously due to heterogeneity and potential biases. …”
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Remote monitoring and teleconsultations can reduce greenhouse gas emissions while maintaining quality of care in cystic fibrosis by Martinus C. Oppelaar, Michiel A. G. E. Bannier, Monique H. E. Reijers, Hester van der Vaart, Renske van der Meer, Josje Altenburg, Lennart Conemans, Lennart Conemans, Bart L. Rottier, Bart L. Rottier, Marianne Nuijsink, Lara S. van den Wijngaart, Peter J. F. M. Merkus, Jolt Roukema

“…BackgroundRemote care usefulness and climate change co-benefits should be addressed simultaneously to incentivize political action.ObjectivesTo assess the changes in healthcare consumption, lung function and greenhouse gas (GHG) emissions during the COVID-19 pandemic in Dutch cystic fibrosis (CF) care.DesignRetrospective multicentre observational study in five Dutch CF centres.MethodsEighty-one participants were included. …”
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The efficacy and safety of nusinersen within the expanded access program in Russia by S. B. Artemieva, L. M. Kuzenkova, E. S. Ilyina, Yu. A. Kursakova, L. M. Kolpakchi, E. Yu. Sapego, A. A. Golenko, S. G. Popovich, D. V. Parshin, O. A. Shidlovskaya, Yu. O. Papina, A. V. Monakhova, D. V. Vlodavets

“…Overall motor development and motor function was assessed using the Hammersmith Infant Neurological Status Scale Part 2 and the Philadelphia Pediatric Hospital Neonatal Motor Scale. …”
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Clinical and Histopathological Determinants for Kidney Allograft Survival in the Eurotransplant Senior Program (ESP) at the Time of Allocation by Tom N. Langer, Tom N. Langer, Thorsten Wiech, Thorsten Wiech, Mercedes Noriega, Sergey Biniaminov, Tobias B. Huber, Tobias B. Huber, Lutz Fischer, Lutz Fischer, Florian Grahammer, Florian Grahammer, Florian Grahammer, Malte A. Kluger, Malte A. Kluger

“…Arteriolosclerosis (arteriolar hyalinosis) correlated with a higher risk for primary non-function (P < 0.05). The number of HLA mismatches was not significantly associated with graft outcome. …”
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Analysis of Energy Metabolism and Lipid Spatial Distribution in Hypoxic-Ischemic Encephalopathy Revealed by MALDI-MSI by Xingxing Zhao, Peipei Chen, Lun Yu, Chuchu Gao, Sannan Wang, Zuming Yang, Zongtai Feng

“…By targeting xanthine metabolic pathways, restoring mitochondrial function, and intervening in region-specific lipid remodeling, brain energy homeostasis may be improved and neurological damage attenuated. …”
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Correlates and determinants of physical activity among older adults of lower versus higher socio-economic status: a systematic review and meta-analysis by Olivia S. Malkowski, Jessica Harvey, Nick P. Townsend, Mark J. Kelson, Charlie E. M. Foster, Max J. Western, Physical Activity Inequalities in Later Life consortium

“…Future longitudinal and experimental research should gauge the suitability of these correlates as intervention targets.…”
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VOKATIVE AS AN ELEMENT OF UKRAINIAN SPEECH ETIQUETTE (SPECIAL FEATURES AND TRENDS IN THE FRAMEWORK OF THE NEWEST COMMUNICATIVE DISCOURSE) by Olena M. Turchak

“…Vocative case performs the function of the addressee`s action. In contrast to the Ukrainian language, nominative case performs two functions – nominative and appellative in the Russian language The vocative case in the Ukrainian language should be considered taking into account the category of gender, number, declination and group. …”
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Vibrotactile Feedback Strategies for Trunk-Stabilizing Exercises in a Home-Based Scenario: Qualitative Interview Study Among Physiotherapists by Kaya Holzmeyer, Lisa-Marie Lüneburg, Luca Oppici, Philipp Flößel, Doris Lachmann, Jens Krzywinski, Susanne Narciss

“…We identified key feedback characteristics recommended by physical therapists: reduced frequency, differentiated content, multimodal feedback, and trunk-proximal vibrotactile cues. These approaches should be tested in hypotheses-driven research and further patient studies should be conducted.…”
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Framework for Kidney Health Follow‐Up Among Neonates With Critical Cardiac Disease: A Report From the Neonatal Kidney Health Consensus Workshop by Stephen M. Gorga, Tara Beck, Paulomi Chaudhry, Marissa J. DeFreitas, Dana Y. Fuhrman, Catherine Joseph, Catherine D. Krawczeski, David M. Kwiatkowski, Michelle C. Starr, Matthew W. Harer, Jennifer R. Charlton, David J. Askenazi, David T. Selewski, Katja M. Gist

“…Thirty percent to 50% of adults with congenital heart disease have impaired kidney function, even in the absence of prior kidney injury episodes. …”
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The characteristics and prognosis of bronchiectasis patients with airflow limitation: a prospective longitudinal study by Yuanting Cai, Linbin Xv, Zili Zhu, Shiyi He, Tianyu Sun, Chao Cao

“…Patients with bronchiectasis concomitant with airflow limitation should be identified as early as possible, and individualized treatment methods should be formulated.…”
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Structural optimization and performance evaluation of a sugarcane leaf mulching machine by Weihua Huang, Shuo Wang, Chang Ge, Lijiao Wei, Dongjie Du, Zhaojun Niu, Ming Li, Zhenhui Zheng

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