Length–Weight Distribution of Non-Zero Elements in Randomized Bit Sequences by Christoph Lange, Andreas Ahrens, Yadu Krishnan Krishnakumar, Olaf Grote

“…Cryptographic outputs should look more random than deterministic in order to provide an attacker with as little information as possible. …”
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Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo by Gonzalo I. Mendoza-Ochoa, J. David Barrass, Isabella E. Maudlin, Jean D. Beggs

“…Unexpectedly, depleting factors such as Prp16 or Prp22, that are known to function at the second catalytic step or later in the splicing pathway, resulted in a defect in the first step of splicing, and accumulation of arrested spliceosomes. …”
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Unveiling the Anti-Aging Potential of Marine Natural Bioproducts by Nedeljka Rosic

“…Aging is a natural process resulting in the progressive impairment of multiple functions in the human body, leading to a decline in cellular functionality and the development of aging-related diseases. …”
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Xanthine oxidase inhibitors in asymptomatic hyperuricemia by O. V. Zhelyabina, M. S. Eliseev

“…The use of xanthine oxidase (XO) inhibitors in a number of trials was accompanied by a reduction in the risk of CVD and by an improvement in renal function. Epidemiological studies have also established that there is a significant positive correlation of the serum concentration of UA with obesity, dyslipidemia, insulin resistance, and cerebrovascular and peripheral vascular diseases. …”
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Mechanistic insights into the sleep-glymphopathy-cerebral small vessel disease loop: implications for epilepsy pathophysiology and therapy by Zaw Myo Hein, Zaid Adnan Subhi Al-Zaghal, Mazira Muhammad Ghazali, Usman Jaffer, Hafizah Abdul Hamid, Hafizah Abdul Hamid, Muhammad Zulfadli Mehat, Muhammad Zulfadli Mehat, Muhammad Danial Che Ramli, Che Mohd Nasril Che Mohd Nassir

“…Targeting sleep modulation, glymphatic function, and cerebrovascular health presents a promising avenue for therapeutic intervention. …”
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Exposome and Metabolome Analysis of Sugarcane Workers Reveals Predictors of Kidney Injury by Arthur D. Stem, Stephen Brindley, Keegan L. Rogers, Adil Salih, Carlos A. Roncal-Jimenez, Richard J. Johnson, Lee S. Newman, Jaime Butler-Dawson, Lyndsay Krisher, Jared M. Brown

“…Future work should determine whether long-term occupational exposure to silica and pesticides across multiple seasons contributes to CKD in these workers. …”
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Risk factors for cardiovascular diseases in patients received complex treatment for cranial and craniospinal tumors in childhood by A. I. Novikova, M. G. Poltavskaya, M. G. Pavlova, P. Sh. Chomakhidze, V. M. Sotnikov, N. A. Potemkina, A. A. Bykova, Z. K. Salpagarova, Z. Z. Fashafsha, T. V. Soboleva, O. V. Andreeva, O. G. Zheludkova, D. А. Andreev

“…To study the traditional risk factors for cardiovascular disease (CVD), indicators of endothelial function and exercise tolerance in patients received complex treatment for cranial and craniospinal tumors in childhood, including radiation therapy.Material and methods. …”
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Heart failure, dementia is associated with increased stroke severity, in‐hospital mortality and complications by Lijun Zuo, YanHong Dong, Yang Hu, Zixiao Li, Hongqiu Gu, Xingquan Zhao, Yongjun Wang

“…Conclusions Stroke patients with dementia and HF have an increased risk of in‐hospital mortality and complications. Future studies should strengthen the risk factor control among individuals with both dementia and HF for stroke prevention.…”
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Primary repair vs arthroscopic reconstruction for proximal anterior cruciate ligament tears: a comparative study by Sergey A. Gerasimov, Ekaterina A. Morozova, Daria A. Naida, Denis O. Kolmakov, Andrey A. Zykin, Ekaterina V. Khramtsova

“…Primary ACL repair still retains a large number of limitations. It cannot and should not replace ACL reconstruction. However, with strict adherence to the indications and surgical technique, primary ACL repair demonstrates comparable functional outcomes.…”
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Multidimensional assessment of women after severe maternal morbidity: the COMMAG cohort study by Renato T Souza, José Guilherme Cecatti, Maria Laura Costa, Elton C Ferreira, Rodolfo C Pacagnella, Carla Silveira, Carla B Andreucci, Dulce Maria Toledo Zanardi, Juliana P Santos, Carina R Angelini, Mary A Parpinelli, Maria Helena Sousa

“…Controls were randomly selected among women without SMM admitted to the same maternity and same time of childbirth.Primary and secondary outcome variables Validated tools were applied, addressing post-traumatic stress disorder (PTSD) and quality of life (SF-36) by phone, and then general and reproductive health, functioning (WHO Disability Assessment Schedule), sexual function (Female Sexual Function Index (FSFI)), substance abuse (Alcohol, Smoking and Substance Involvement Screening Test 2.0) and growth/development (Denver Developmental Screening Test) of children born in the index pregnancy in a face-to-face interview.Results All instruments were applied to 638 women (315 had SMM; 323 were controls, with the assessment of 264 and 307 children, respectively). …”
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Polycystic liver disease in a third level hospital by Luis A. Torrez-Arias, Maria F. Higuera-De la Tijera

“…Most growth monitoring should be performed with imaging studies and questionnaires for symptoms and quality of life. …”
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Ways of Improving the Results of Treatment for Pulmonary Thromboembolism by M. I. Neimark, A. G. Zaltsman, A. V. Akatov, A. V. Beller, S. V. Zaitsev, M. V. Boyarkov

“…Objective: to reveal the predictors of clinically significant deterioration of cardiac pump function resulting from alveolar opening maneuver (AOM) (mobilization) made early after extracorporeal circulation during standard cardiosurgery. …”
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Monitoring Plasma Concentrations of Intravenously Administered Fosfomycin to Prevent Drug-Related Adverse Events: A Retrospective Observational Study by Kathrin Marx, Nina Malmström, Marie Quast, Annette Glas, Ralph Wendt, Martina Kinzig, Fritz Sörgel, Maike Fedders, Thilo Bertsche, Christoph Lübbert

“…In particular, the impact of acute renal insufficiency on fosfomycin plasma concentrations should be considered. Individualized fosfomycin dosing based on TDM and the intensive monitoring of renal function contribute to reducing drug-related side effects.…”
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Exercise-Induced Excessive Blood Pressure Elevation Is Associated with Cardiac Dysfunction in Male Patients with Essential Hypertension by Binfeng Xia, Pengyu Cao, Li Zhang, Huihui Huang, Rongyu Li, Xia Yin

“…EH patients with exercise-induced cardiac dysfunction have reduced peak cardiac output and exercise tolerance and impaired vascular diastolic function. CPET examination should be performed on EH patients and EH patients with exercise-induced cardiac dysfunction to develop precise drug therapy and effective individual exercise prescription, to avoid arteriosclerosis and exercise-induced cardiac damage. …”
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Assessing the Skeletal Muscle Pump During Lower Limb Counterpressure: Lags and Causality in Cardiovascular Regulation by Silvin P. Knight, Eoin Duggan, Feng Xue, Roman Romero‐Ortuno

“…The study provides a novel methodological framework for assessing skeletal muscle pump function and its impact on cardiovascular dynamics. …”
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Identification of FABP5 as an immunometabolic marker in human hepatocellular carcinoma by Yan Lu, Shuang Zhou, Han Wang, Fangming Liu, Weiren Liu, Chunhui Yang, Mengxin Tian, Guangshuai Jia, Bijun Zhu, Mingxiang Feng, Tiankui Qiao, Xinxin Wang, Wei Cao, Xiangdong Wang, Yinghong Shi, Duojiao Wu

“…The immunometabolic marker FABP5 should be investigated in larger, longitudinal studies to determine their potential as prognostic biomarkers for HCC.…”
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Pyrroloquinoline Quinone (PQQ): Its impact on human health and potential benefits by Tingdong Yan, Muhammad Farrukh Nisar, Xiaomeng Hu, Jieming Chang, Yichen Wang, Yan Wu, Zhaoguo Liu, Yi Cai, Jia Jia, Yanming Xiao, Chunpeng Wan

“…Future research directions should focus on determining the optimal dosages of PQQ for specific health outcomes and assessing its long-term effectiveness and safety. …”
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Neuromuscular factors predicting lower limb explosive strength in male college sprinters by YanJin Li, QiaoFeng Guo, Jia Shao, YanMing Gan, YaJing Zhao, Yue Zhou, Yue Zhou

“…Therefore, training related to the neural function of sprinters should be emphasized. In addition, H reflex and V wave can be used widely to assess and monitor the neural function of sprinters in future research. …”
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Kidney Dysfunction and Pathology in the Setting of Hemophagocytic Lymphohistiocytosis by Miroslav Sekulic, Ibrahim Batal, Satoru Kudose, Dominick Santoriello, M. Barry Stokes, Belinda Jim, Hans-Peter Marti, Øystein Eikrem, Jai Radhakrishnan, Vivette D. D’Agati, Glen S. Markowitz

“…Conclusion: Kidney dysfunction in HLH should not be assumed to be solely attributable to ATI, and in certain scenarios a kidney biopsy may be warranted.…”
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X-inactive-specific transcript: a long noncoding RNA with a complex role in sex differences in human disease by Dan N. Predescu, Babak Mokhlesi, Sanda A. Predescu

“…In this review, we summarize recent knowledge about XIST structure/function correlation and involvement in human disease with focus on XIST abnormal expression in males. …”
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