Suggested Topics within your search.
Suggested Topics within your search.
-
3821
Pharmacokinetics and Safety of HRS-1780 in Renal Impaired Subjects: A Multicenter, Non-Randomized, Open-Label Study [Corrigendum]
Published 2025-06-01“…Page 3760, first line, the text “Our current study had similar findings” should read “Our study observed an increase in the exposure to HRS-1780 with both mild and moderate renal impairment compared with normal renal function, which however, was not statistically significant. …”
Get full text
Article -
3822
Genetic and Gene-by-Environment Influences on Aggressiveness in Dogs: A Systematic Review from 2000 to 2024
Published 2025-08-01“…The findings highlight the relevance of gene–environment interactions but underscore that aggression is often poorly defined and measured across studies. Future research should prioritize standardized phenotyping tools, broader breed inclusion, and the functional validation of genetic findings. …”
Get full text
Article -
3823
Phthalates and Non-Phthalate Plasticizers and Thyroid Dysfunction: Current Evidence and Novel Strategies to Reduce Their Spread in Food Industry and Environment
Published 2025-03-01“…Thyroid hormones (THs) play a crucial role in various biological functions, including metabolism, cell growth, and nervous system development, and any alteration involving the structure of the thyroid gland and TH secretion may result in thyroid disease. …”
Get full text
Article -
3824
The neuroprotective role of CncC in a Drosophila model of Parkinson's disease.
Published 2025-01-01“…This chemical affects mitochondrial function by blocking electron transfer, resulting in increased reactive oxygen species production and accumulation. …”
Get full text
Article -
3825
Epidemiological patterns and therapeutic approaches of toad toxin poisoning in a retrospective case study
Published 2025-02-01“…Recent studies have increasingly confirmed its pharmacological benefits, including cardioprotection, anesthetic effects, anti-inflammatory properties, enhancement of sexual function, and antineoplastic activities. This toxin is applied in the treatment of diverse medical conditions such as chronic bronchitis, pharyngitis, and colon cancer. …”
Get full text
Article -
3826
Unlocking the Influence of Digital Marketing Strategies on Startup Performance: A Case Study in Bangladesh
Published 2025-03-01“…The findings suggest enterprises with less than 10 years of Operation should emphasize digital marketing specifically social media marketing to leverage the expanding digital trend, particularly in the restaurant, retail, and textile industries. …”
Get full text
Article -
3827
The ASSIST Trial: Acute Effects of Manipulating Strength Exercise Volume on Insulin Sensitivity in Adults Living With Obesity: A Randomized Controlled, Crossover, Clinical Trial
Published 2025-07-01“…ABSTRACT Aims To investigate the influence of exercise volume on the transient increase in insulin sensitivity and β‐cell function that occurs in the hours following an acute bout of strength exercise. …”
Get full text
Article -
3828
Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis
Published 2025-07-01“…Clinical significance: Curcumin (200–500 mg/day) and tanshinone are recommended as adjuvant treatment options for COPD, but blind combination should be avoided; the safety of ingredients such as quercetin needs to be further verified. …”
Get full text
Article -
3829
Effects of an integrated social-art intervention on cognitive and psychosocial outcomes among older adults with mild cognitive impairment in nursing homes: a mixed methods study
Published 2025-05-01“…Quantitative outcomes were measured at baseline (T0), immediately post-intervention (T1), and at 24-week follow-up (T2), with global cognitive function as the primary outcome, and specific cognitive functions, psychosocial indicators, functional abilities, and quality of life as secondary outcomes. …”
Get full text
Article -
3830
Impact of congenital cytomegalovirus infection on vestibular dysfunction and hearing outcomes in a cohort of children
Published 2025-05-01“…Therefore, vestibular evaluation should be included in the audiological work up and follow-up in children with cCMV.…”
Get full text
Article -
3831
Do preoperative interventions affect patient satisfaction or expectation fulfilment following total hip arthroplasty? A systematic review
Published 2025-06-01“…Secondary outcomes analysed were pain, function, length of stay (LOS), and postoperative complications. …”
Get full text
Article -
3832
Safety and efficacy of oral edible bird’s nest supplementation: Anti-inflammatory and immunomodulatory benefits for Arabian race stallions during exercise
Published 2025-01-01“…Key objectives included assessing EBN’s impact on hepatic and renal function, hematological profiles, and sialic acid (SA) levels. …”
Get full text
Article -
3833
Digital Behavior Change Interventions to Promote Physical Activity and Reduce Sedentary Behavior Among Survivors of Breast Cancer: Systematic Review and Meta-Analysis of Randomized...
Published 2025-06-01“…However, no significant differences were found in steps (P=.69), time spent in light PA (P=.51), time spent in moderate to vigorous PA (P=.43), sedentary time (P=.18), or physical function (P=.71 or .11). ConclusionsDBCIs effectively improve upper-body mobility, function, quality of life, and pain management in survivors of breast cancer. …”
Get full text
Article -
3834
Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial
Published 2025-01-01“…Alternative provocative tests or biomarkers should be explored.…”
Get full text
Article -
3835
Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission
Published 2024-12-01“…Clinical pharmacists should regularly analyze DDIs in prescribed pharmaco-therapy which enhances medication safety and also contributes to the quality of provided health care.…”
Get full text
Article -
3836
Application of Levi’s Muscle Index in frailty assessment: comparison of bioimpedance measures among older adults
Published 2025-06-01“…IntroductionFrailty is prevalent among older adults and is characterized by reductions in physical function and muscle quality. Despite the emerging clinical utility of bioelectrical impedance analysis (BIA) and phase angle (PhA) as a bioimpedance index, little is known about how bioimpedance indices such as Levi’s Muscle Index (LMI), reactance/height (Xc/Height), and resistance/height (R/Height), relate to physical function and frailty.MethodsThis cross-sectional study examined 208 community-dwelling older adults (female, n = 183; age = 74.2 ± 6.9 years; BMI = 30.4 ± 6.4 kg/m2) to compare physical function measures and bioimpedance indices across frailty categories determined by the FRAIL questionnaire. …”
Get full text
Article -
3837
Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis
Published 2025-01-01“…Conclusions The non-insulin-based IR indicators, including TyG index, METS-IR and eGDR, were independently associated with the frailty progression and physical function decline. Monitoring and managing abnormal glucose metabolism should be recommended as a part of comprehensive strategies to prevent or delay the progression of frailty.…”
Get full text
Article -
3838
The analysis of risk factors for diabetic kidney disease progression: a single-centre and cross-sectional experiment in Shanghai
Published 2022-06-01“…Women should pay attention to controlling inflammation and TGs, and men should strictly control blood pressure. …”
Get full text
Article -
3839
Control Indicators for Typical Persistent Organic Pollutants in Lake Sediments
Published 2025-05-01“…Combined with the co-distribution patterns of heavy metal pollution, the response relationship between pollutant concentrations and lake functions was established. The results showed that control indicators for dioxins should be strictly graded according to lake functions: 10 ng/kg for lakes of landscape and storage functions (aligned with China’s Class I construction land standards), 5 ng/kg for lakes used for agricultural irrigation (referencing German agricultural land standards), and 1 ng/kg for lakes used for fishery purposes (based on background values and Dutch standards). …”
Get full text
Article -
3840
Recurrent patellar dislocation: treatments and challenges
Published 2025-02-01“…We believe that regardless of the surgical method used, patellar dislocation should not occur at 0°–90° of postoperative knee flexion and extension, and the range of motion should not be limited. …”
Get full text
Article