CARDIORENAL SYNDROME IN PATIENTS WITH CHRONIC HEART FAILURE AS A STAGE OF THE CARDIORENAL CONTINUUM (PART I): DEFINITION, CLASSIFICATION, PATHOGENESIS, DIAGNOSIS, EPIDEMIOLOGY by E. V. Reznik, I. G. Nikitin

“…Cardiorenal syndrome type 1 or 2 develops in most cases of heart failure: cardiorenal syndrome presents with the development ofchronic kidney disease in patients with chronic heart failure and acute kidney injury in patients with acute heart failure. Impaired renal function has an unfavorable prognostic value. It leads to an increase in the mortality of patients with heart failure. …”
Get full text

Record Keeping Systems and Service Delivery in Uganda: Case Of Kabale District Local Government by Turyasingura John Bosco, agaba moses, Kabagambe Jesse David, Barigye Godfrey

“…To do this, emphasis should be placed on relationship-building, objectivity, punctuality, and communication. …”
Get full text

The magnitude of untreated dental caries and its predictors among pregnant women attending antenatal care at health facilities in Gondar town, Northwest Ethiopia by Amare Teshome Tefera, Solomon Berhe, Samuel Seifu, Martha Solomon, Zelalem Ayichew, Aynishet Adane, Wubet Birhan, Tadesse Awoke Ayele, Shashe Zewdu

“…Abstract Introduction Pregnancy-associated hormonal alterations and reduced immunological function contribute to diminished oral hygiene, thereby increasing the susceptibility of pregnant women to oral diseases, especially dental caries. …”
Get full text

Estimation and prediction of water conservation in the upper reaches of the Hanjiang River Basin based on InVEST-PLUS model by Pengtao Niu, Zhan Wang, Jing Wang, Yi Cao, Peihao Peng

“…Therefore, through the visualization analysis of the LULC changes of URHRB and water conservation function, it is found that the land and resources department should pay attention to the LULC changes of water sources and adjust the territorial spatial planning in time to cope with the huge water conservation gap in the future.…”
Get full text

Exploring the Antifibrotic Mechanisms of Ghrelin: Modulating TGF-β Signalling in Organ Fibrosis by Mei Li, Chang Zheng, Huiyi Wang, Shan Wang

“…This imbalance can lead to compromised organ function and potential failure, posing significant health risks. …”
Get full text

The effect of 4 weeks of virtual reality, interval nordic walking and ambient music interventions on cardiorespiratory recovery in the elderly patients with HFrEF in response to ca... by Ardavan Taheri, Maede Makaremi, Valiollah Dabidiroshan

“…HR, SBP, RPP and cardiorespiratory function (VO2peak, O2 pulse and time-to-exhaustion (TTE) were measured using a 12-lead ECG system, immediately after and at 1st and 3rd minute of recovery following an incremental CPET, before and after 4 weeks of interventions. …”
Get full text

Council of Experts: chronic shoulder pain as a multidisciplinary problem by A. E. Karateev, A. M. Lila, N. V. Zagorodniy, L. I. Alekseeva, S. V. Arkhipov, V. V. Arkov, M. S. Makarov, A. P. Rachin, V. A. Shirokov, M. N. Khokhlova, V. A. Nesterenko

“…In CSP, it is necessary to exclude septic, oncological, visceral, systemic rheumatic and other diseases, as well as musculoskeletal pathology of the cervical spine, upper chest and back, which can cause pain in the shoulder region.Therapy for diseases that cause CSP should be personalized and complex, aimed at maximum pain control and restoration of function. …”
Get full text

Method of Estimating the Equivalence of Dissolution Profiles: a Modern View (Review) by I. E. Shohin, N. S. Bagaeva, E. A. Malashenko, V. N. Kuzina

“…If f2 is not used, it is necessary to use model-dependent and model-independent methods that are statistically correct, and their use is sufficiently justified (difference factor f1, Weibull distribution function, comparison of release degrees at different time points (according to the student's t-criterion). …”
Get full text

Everolimus in clinical practice after liver transplantation: a single-center experience by O. A. Gerasimova, D. A. Granov, F. K. Zherebtsov

“…Everolimus allows maintaining of a stable renal function to prevent progression of renal failure; conversion should be initiated as early as possible. …”
Get full text

Open-label randomised clinical trial investigating whether robot-assisted kidney transplantation can reduce surgical complications compared to open kidney transplantation (ORAKTx):... by Milla Ortved, Julia Dagnæs-Hansen, Hein V. Stroomberg, Thomas Kistorp, Malene Rohrsted, Søren Schwartz Sørensen, Andreas Røder

“…Abstract Background Kidney transplantation is the ultimate treatment for end-stage kidney disease. Function of the kidney graft is not only dependent on medical factors but also on a complication-free surgical procedure. …”
Get full text

Patterns of obesity development before the diagnosis of type 2 diabetes: the Whitehall II cohort study. by Dorte Vistisen, Daniel R Witte, Adam G Tabák, Christian Herder, Eric J Brunner, Mika Kivimäki, Kristine Færch

“…They experienced slightly worsening of beta cell function and insulin sensitivity from 5 years prior to diagnosis. …”
Get full text

Digital Interventions for Cognitive Dysfunction in Patients With Stroke: Systematic Review and Meta-Analysis by Chen Wang, Min Liu

“… Abstract BackgroundIn recent years, digital technologies have shown possibilities for improving cognitive function after stroke, but their effectiveness and treatment options vary, the optimal treatment remains unclear, and the current evidence is somewhat contradictory. …”
Get full text

Effects of high-intensity interval training in a cold environment on arterial stiffness and cerebral hemodynamics in sedentary Chinese college female students post-COVID-19 by Xiangyuan Chen, Niyuan Hu, Huifeng Han, Guoliang Cai, Ying Qin

“…Future research should further explore the mechanisms by which sedentary behavior, post-COVID-19 recovery status, and adaptation to cold environments collectively influence cardiovascular function and cerebral hemodynamics, providing a more comprehensive understanding of these factors.…”
Get full text

Biomechanical Analysis of Different Pacifiers and Their Effects on the Upper Jaw and Tongue by Luca Levrini, Luigi Paracchini, Luigia Ricci, Maria Sparaco, Stefano Saran, Giulia Mulè

“…Choosing the right pacifier is essential to avoid potential negative effects on craniofacial development and to ensure that the benefits of proper oral function are maintained. Therefore, healthcare professionals and parents should consider these biomechanical factors when introducing pacifiers to newborns.…”
Get full text

Exploring the Impact of Stroke on Lower Limb Proprioception: Insights into Physiotherapy Interventions for Rehabilitation: Systematic Review by Trishna Saikia Baruah, Pratap Chandra Sarma

“…Emerging therapies, including telerehabilitation and neurostimulation, highlight the potential for innovative approaches in stroke rehabilitation and functional recovery. Conclusion: This review highlights that targeted physical therapy interventions, such as sensory re-education and balance training, significantly improve stroke survivors' proprioception, balance, and motor function, promoting better functional recovery. …”
Get full text

The clinical efficacy of proprioceptive neuromuscular facilitation technique in the treatment of scapulohumeral periarthritis: a systematic review and meta-analysis by Chengyu Zhu, Xueyan Huang, Jiaying Yu, Ying Feng, Haifang Zhou

“…In clinical work, medical staff should pay attention to the psychological state of patients with SP. …”
Get full text

Deciphering the role of hsa-piR-775 in primary ovarian insufficiency through FOXG1 modulation by Hui Ding, Xuewei Qin, Yu Li, Yuan Fang, Lina Wu

“…This supports piRNAs’ potential as biomarkers and therapeutic targets in POI. Future studies should focus on validating these findings in larger cohorts and exploring piRNA-based therapeutic interventions for POI.…”
Get full text

The effect of transcranial direct current stimulation on the interplay between executive control, behavioral variability and mind wandering: A registered report by Andreas Alexandersen, Gábor Csifcsák, Josephine Groot, Matthias Mittner

“…Furthermore, we recommend that previously reported effects of tDCS on mind wandering and other cognitive functions should only be accepted after a successful pre-registered replication.…”
Get full text

Impact of Terminalia chebula Retz polysaccharide and Rubia cordifolia L. processed Terminalia chebula Retz polysaccharides on cyclophosphamide-induced immunosuppression in Chinese... by Jing Wang, Tiejin Tong, Qiang Wu, Min He

“…These findings highlight RTCP’s potential as a natural immunomodulator in poultry. Further research should optimize dosing and explore gut-microbiota-immune interactions to enhance therapeutic applications.…”
Get full text