The Different Effects of Atorvastatin and Pravastatin on Cell Death and PARP Activity in Pancreatic NIT-1 Cells by Ya-Hui Chen, Yi-Chun Chen, Chin-San Liu, Ming-Chia Hsieh

“…Thus, the PARP1 activation should be considered in the development of effective statin therapies for diabetes. …”
Get full text

Henoch Schonlein Purpura as a Cause of Renal Failure in an Adult by Shweta Kukrety, Pradeepa Vimalachandran, Rajesh Kunadharaju, Vishisht Mehta, Agnes Colanta, Mahmoud Abu Hazeem

“…Purpuric skin rash with renal involvement should raise suspicion for HSP. This is the oldest known patient with HSP.…”
Get full text

Towards Noninvasive Detection of Oesophageal Varices by Kara Rye, Robert Scott, Gerri Mortimore, Adam Lawson, Andrew Austin, Jan Freeman

“…Current guidelines recommend that all cirrhotic patients should undergo screening endoscopy at diagnosis to identify patients with varices at high risk of bleeding who will benefit from primary prophylaxis. …”
Get full text

Role of Pseudoexons and Pseudointrons in Human Cancer by Maurizio Romano, Emanuele Buratti, Diana Baralle

“…As a result, eukaryotic cells have developed a very efficient macromolecular machinery, called the spliceosome, to correctly recognize the pre-mRNA sequences that need to be inserted in a mature mRNA (exons) from those that should be removed (introns). In healthy individuals, alternative and constitutive splicing processes function with a high degree of precision and fidelity in order to ensure the correct working of this machinery. …”
Get full text

Revisiting the Corneal and Blink Reflexes for Primary and Secondary Trigeminal Facial Pain Differentiation by Zafar Ali Khan

“…Dental surgeons and oral and maxillofacial surgeons should consider corneal reflex in neurological assessment of patient presenting with trigeminal neuralgia-like symptoms. …”
Get full text

Reinsurance: Substance, range and importance by Petrović-Tomić Nataša

“…Reinsurance - at least in Serbian law - represents one of the institutes of Insurance Law of whom a little is known. It should not be surprising as the contract of reinsurance traditionally is not regulated in civil codes or laws on contract of insurance. …”
Get full text

Standard Deviation of Fiber-Coupling Efficiency for Free-Space Optical Communication Through Atmospheric Turbulence by Woohyeon Moon, Hoon Kim

“…Next, a new formula for the second moment of coupled optical power is developed by introducing the spatial filter to the fourth-order coherence function. The computer simulation is carried out to evaluate the accuracy of the formulas. …”
Get full text

Chronic Persistent Asthma: A Review of Medicines in the Step-Up Approach by Elvis Irusen

“…With this therapeutic armamentarium the practitioner should aim to achieve the goals of asthma therapy that are focused on clinical and lung function parameters. …”
Get full text

Exercise Dysfunction and Pulmonary Rehabilitation Strategies in COPD Patients at High-Altitudes: A Review by Fan LX, Wang HJ

“…Effective pulmonary rehabilitation (PR) strategies are essential and should encompass individualized assessments, tailored exercise programs, supplemental oxygen therapy, and nutritional and psychological support. …”
Get full text

E-democracy: Slacktivism vs civic activism by Albina BORISENKO

“… There are many studies in Russia on how the open government and e-democracy should be arranged, what tools they use, what has been done, and what can be done in the future. …”
Get full text

Hyperkalemia and Renin–Angiotensin–Aldosterone System Inhibitors Dose Therapy in Heart Failure With Reduced Ejection Fraction by Giuseppe MC Rosano, Ilaria Spoletini, Cristiana Vitale, Stefan Agewall

“…To reduce mortality in these patients, RAASi should be uptitrated to the maximally tolerated dose. …”
Get full text

Anticoagulant therapy for the prevention of recurrent stroke in patients with atrial fibrillation: a comprehensive risk management by V. A. Sorokoumov

“…This approach, along with the risk of recurrent stroke and possible bleeding events, takes into account other risks that can significantly worsen the prognosis and health of a patient with AF, such as the risk of coronary events, impairment of renal function, and cognitive impairment that can lead to low adherence to treatment. …”
Get full text

Planned spatial arrangement of high-speed railway lines in Poland by Juliusz Engelhardt

“…On the basis of this analysis, a general recommendation was formulated that when designing the spatial and geographical layout of new high-speed railway lines, the layout of passenger flows inside the country should also be taken into account. The new concepts of the geographic route of high-speed railway lines related to the railway component of the project to build the Central Communication Port (CPK) in Poland do not fully take into account this postulate because they have been completely subordinated to the function of transporting and transporting passengers to the planned central airport. …”
Get full text

The Vandal habrosýne and its Significance in Procopius’ Narrative on the Rise and Fall of the Vandal State by Michał Stachura

“…However, a closer look at the actual function of this passage in Procopius’ narrative on the rise and fall of the Vandal state brings this seemingly obvious interpretation into question. …”
Get full text

Antibody-Negative Relapse of Goodpasture Syndrome with Pulmonary Hemorrhage by Charlene L. Rohm, Sara Acree, Aseem Shrivastava, Asif A. Saberi, Louis Lovett

“…Clinicians should have enhanced awareness of this atypical presentation of a rare disease.…”
Get full text

Hypokalemic Paralysis Secondary to Immune Checkpoint Inhibitor Therapy by Pragathi Balakrishna, Augusto Villegas

“…On discharge, paralysis was resolved. Renal function and potassium were normalized. Nivolumab was discontinued, and he was started on pembrolizumab. …”
Get full text

PPV Criterion of a Defect Rock Slope under Blasting SV-Waves by Shiwei Lu, Yingkang Yao, Yongsheng Jia, Jinshan Sun, Zhen Zhang

“…In the background of an iron mine in central China, the relation between the stress field and the PPV of the incident wave is analyzed and the function of PPV threshold is deduced using both deterministic and probabilistic methods to evaluate the slope stability. …”
Get full text

Prosthodontic Rehabilitation Alternative of Patients with Cleft Lip and Palate (CLP): Two Cases Report by Emrah Ayna, Emine Göncü Başaran, Köksal Beydemir

“…With education and appropriate recall, the patients should be able to maintain their oral health.…”
Get full text

Uterine fibroids of gigantic size: a clinical case by Marina V. Koval, Anna M. Bogdanova, Georgy P. Svetlakov, Irina Yu. Kovaleva, Vilena I. Chashchina

“…Uterine fibroid (UF) is the most common benign tumor in the structure of gynecological diseases of the female reproductive system, accounting for 45–70% of the total cases. Special attention should be paid to the rare cases with gigantic UFs. …”
Get full text

Efficacy of Lockdowns in Africa by Daglous Makumbe

“…Except for a few countries in Europe and Africa that did not act homogeneously, the rest of the world ceased to function. Whilst lockdowns were effective in western countries, in the African continent, it was a different case. …”
Get full text