The Effect of Overcoming the Digital Divide on Middle Frontal Gyrus Atrophy in Aging Adults: Large-Scale Retrospective Magnetic Resonance Imaging Cohort Study by Yumeng Li, Xinyue Zhang, Jiaqing Sun, Junying Zhang, Aiqin Zhu, Xin Li, Zhanjun Zhang

“…ResultsThe DD group showed significant deficits in executive function (tPdtPdPtPP ConclusionsOlder adults who overcome the DD demonstrate preserved gray matter structure and slower cognitive decline, particularly in frontotemporal regions critical for executive function. …”
Get full text

A Parametric Analysis of the Effect of Hybrid Nanoparticles on the Flow Field and Homogeneous-Heterogeneous Reaction between Squeezing Plates by Wajid Ullah Jan, Muhammad Farooq, Aamir Khan, Asma Alharbi, Rehan Ali Shah, Rashid Jan, Sahar Ahmed Idris

“…To check the validity of the results obtained from the shooting mode, the Matlab built-in function BVP4c and Mathematica built-in function homotopy analysis method (HAM) are used. …”
Get full text

Migraine is a risk factor for dementia: a systematic review and meta-analysis of cohort studies by Wenyan Zhu, Yijun Zhan, Jian Pei, Qinhui Fu, Ruiqi Wang, Qianwen Yang, Qingyang Guan, Like Zhu

“…Migraine affects cognitive function during an attack, but reports are inconsistent on whether the effect of migraine on cognitive function persists and increases the risk of developing dementia. …”
Get full text

A SINGLE MECHANISM OF ACTION OF HYPOLIPIDEMIC DRUGS. BASIC PRINCIPLES OF PRIMARY PREVENTION OF ATHEROSCLEROSIS, ATHEROMATOSIS AND CORONARY SYNDROME by V. N. Titov, M. Yu. Kotlovskiy, Ye. V. Kurdoyak, A. V. Yakimenko, I. Yu. Yakimovich, N. V. Aksyutina, Yu. V. Kotlovskiy, A. M. Dygai

“…Hypolipidemic drugs are not the means of primary prevention of hyperlipidemia and atherosclerosis. This prevention should be based on normalization of the biological function of trophology and biological reaction of exotrophy and correction of quality and quantity of food according to real, quite limited functional possibilities ofHomo sapiens. …”
Get full text

Evaluating the efficacy of Internet-Based Exercise programme Aimed at Treating knee Osteoarthritis (iBEAT-OA) in the community: a study protocol for a randomised controlled trial by Abhishek Abhishek, Sameer Akram Gohir, Paul Greenhaff, Ana M. Valdes

“…Given the high prevalence of knee OA, a potentially cost-effective, digitally delivered approach to treat knee OA should be trialled. This study aims to explore the benefits of iBEAT-OA (Internet-Based Exercise programme Aimed at Treating knee Osteoarthritis) in modulating pain, function and other health-related outcomes in individuals with knee OA.Methods and analysis A randomised controlled trial was designed to evaluate the efficacy of a web-based exercise programme in a population with knee OA compared with standard community care provided by general practitioners (GPs) in the UK. …”
Get full text

Comparative efficacy of different anti-shortening screws in preventing postoperative shortening in displaced femoral neck fractures: a retrospective cohort study by Fengfei Lin, Dongze Lin, Jiajie Liu, Ke Zheng, Chaohui Lin

“…Postoperative shortening is a significant issue, causing functional decline and increased avascular necrosis risk. …”
Get full text

Effects of Physical Exercise on Substance Use Disorder: A Comprehensive Review by Roberto Montón-Martínez, Ismael Castellano-Galvañ, Alba Roldán, Alejandro Javaloyes, Iván Peña-González, José Manuel Sarabia, Diego Pastor, Manuel Moya-Ramón

“…Strength training and concurrent programs provide additional benefits for muscular and cognitive function, although their effects on mental health are less consistent. …”
Get full text

Timing of percutaneous vertebroplasty in the management of osteoporotic vertebral compression fractures: a retrospective cohort study by Huawei Wei, Qiuxue Zhang, Bing Song, Hongwei Yue, Jing Li, Hongjian Zhang, Yanming Wang

“…Early surgical treatment may result in greater pain relief, improved vertebral function, and fewer complications, but patient-specific factors should be considered when determining the optimal surgical timing.…”
Get full text

Sphingosylphosphorylcholine is a substrate for the Pseudomonas aeruginosa phospholipase C/sphingomyelinase, PlcH by Pauline DiGianivittorio, Kristin Schutz, Lauren A. Hinkel, Matthew J. Wargo

“…ABSTRACT Sphingolipids are critical to eukaryotic cell membrane structure and function and play important roles in a variety of host processes that impact infection. …”
Get full text

The Otago Exercise Program's effect on fall prevention: a systematic review and meta-analysis by Chenyu Wang, Sung Min Kim, Sung Min Kim, Sung Min Kim

“…However, it does not significantly impact physical function or upper limb strength. This study has limitations, including potential bias, study heterogeneity, and variations in interventions, which may affect result reliability. …”
Get full text

Age-associated alterations in immune and inflammatory responses in captive olive baboons (Papio anubis) by Michele M. Mulholland, Bharti P. Nehete, Ashley DeLise, Angela M. Achorn, Lisa M. Pytka, Pramod N. Nehete, Pramod N. Nehete

“…Though there are phenotypic and functional similarities between baboons and humans, specific differences exist in immune cell expression and immune function of lymphocytes that should be considered for better experimental outcomes in the development of therapeutics and restoring innate and adaptive immune function in aged individuals.…”
Get full text

A Case of Granulomatous Interstitial Nephritis Associated with <i>Mycobacterium chimaera</i> Disseminated Infection by Martina Cacciapuoti, Maria Mazzitelli, Elena Naso, Maria Loreta De Giorgi, Giovanni Samassa, Valentina Di Vico, Serena Marinello, Lucia Federica Stefanelli, Lorenzo Calò, Annamaria Cattelan, Federico Nalesso

“…The patient was started on antimicrobial therapy with azithromycin, moxifloxacin, rifampicin, and ethambutol while prednisone was tapered down, leading to an improvement in kidney function, blood count, and blood calcium level. Our case suggests that a <i>Mycobacterium chimaera</i> infection should be considered for patients with a history of cardiac surgery and granulomatous interstitial nephritis even in the absence of mycobacteria in a kidney biopsy.…”
Get full text

Cauda Equina Syndrome Without Perineal Sensory Changes or Lower Extremity Neurological Deficits Following Postoperative Spinal Epidural Hematoma: A Case Report and Literature Revie... by Guanyi Liu, Qing Li, Hongfeng Ruan, Bingke Zhu, Weihu Ma, Yong Hu

“…Furthermore, this case highlights the need for continued research into the prevention of SEH and the development of more robust diagnostic criteria for CES in postoperative patients. Future studies should focus on developing more comprehensive guidelines for monitoring postoperative patients, especially regarding urinary function, to aid in the early detection of CES.…”
Get full text

To Study the Thyroid Hormone Levels in Neonates of Rural and Urban Vidarbha Region by Ankita Kondhalkar, Meghali Kaple, Ranjit S. Ambad, Archana Dhok, Ashsish Anjankar

“…In many screening programs, TSH is the primary marker for evaluating thyroid function and is the preferred test for clinicians diagnosing various thyroid disorders. …”
Get full text

Approbation of the mechanism of economic reliability on the example of an industrial enterprise by A. R. Terentyeva

“…The author of the article came to the following conclusions: the implemented mechanism of economic reliability in the activity of an industrial enterprise allows identifying bottlenecks, as well as developing measures to eliminate them, thereby increasing the level of economic reliability; the action of this mechanism should be continuous, since the intensification of technological dynamics is an aggressive factor influencing the efficiency, stability and sustainability of the functioning of an industrial enterprise. …”
Get full text

Single‐stage ACL reconstruction and displaced bucket handle Meniscus repair is associated with lower Meniscus repair failure rates compared to two‐stage surgery by Carolina Kekki, Riccardo Cristiani, Anders Stålman, Christoffer vonEssen

“…Abstract Purpose To compare displaced bucket‐handle meniscus repair (BHMR) failure rates, subjective and objective knee function after BHMR in the setting of ACLR performed as a single‐or two‐stage procedure, and assess factors associated with BHMR survival. …”
Get full text

Association between blood lead levels and constipation in adults: insights from NHANES data (2005–2010) by Yue-Juan Li, Hui Dong, Wen-Xing Chen, Deng-Chao Wang, Miao Yu

“…This may suggest a complex mechanism of lead’s impact on gastrointestinal function. Future research should further explore the causal relationship and potential biological mechanisms between blood lead and constipation.…”
Get full text

More but Smaller: Marine Heatwaves Exacerbate Size Truncation in Overfished Fish Communities in the Skagerrak by Kjell Magnus Norderhaug, Portia Joy Nillos Kleiven, Thomas Wernberg, Ann‐Elin Synnes, Karen Filbee‐Dexter, Sigurd Espeland, Jonas Thormar, Kyrre Heldal Kartveit, Lene Christensen, Even Moland

“…Particular attention should be directed at changes in the distribution and function of foundation species due to their disproportionately important ecological roles. …”
Get full text

Unraveling an uncommon encounter: hypokalemic periodic paralysis with Brugada phenocopy amidst hypokalemia by Razan Dankar, Salim Barakat, Elie El-Charabaty, Syed Salman Hamid Hashmi, Suzanne E. El Sayegh

“…Conclusion: Clinicians should consider including HPP in differential diagnoses of patients presenting with weakness. …”
Get full text

Exploring Oxidative Stress and Metabolic Dysregulation in Lung Tissues of Offspring Rats Exposed to Prenatal Polystyrene Microplastics: Effects of Melatonin Treatment by Hong-Ren Yu, Ching-Yi Tsai, Wei-Ling Chen, Po-Yu Liu, You-Lin Tain, Jiunn-Ming Sheen, Yi-Siang Huang, Mao-Meng Tiao, Chih-Yung Chiu

“…Furthermore, we evaluated the therapeutic effects of melatonin treatment on lung function in 120-day-old offspring and found that melatonin treatment significantly improved lung function and histologic change in the affected offspring. …”
Get full text