Evaluation of Risk Factors, Etiology, Diagnosis, and Auxiliary Diagnostic Methods of Children With Recurrent Wheezing Between 1-24 Months by Ali Furkan Çetin, Öner Özdemir

“…Objective: Wheezing should be evaluated separately from recurrent lower respiratory tract infections in terms of both etiology and risk factors. …”
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THE VASCULAR ENDOTHELIUM FUNCTION INDICATORS IN ORAL LIQUID OF IQOS SMOKING ADOLESCENTS by T.M. Popova, O.A. Nakonechna, O.V. Tishchenko, L.S. Kryvenko

“…The revealed changes indicate the endothelial dysfunction in young smokers. The development of pathological processes in the vascular endothelium depends on the smoking duration. …”
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Thyroid-stimulating hormone and thyroid hormone levels in association with occupational hazards in male coal miners by Yingshi DAI, Yingjun CHEN, Yingqi LUO, Yanhui LIU, Liuquan JIANG, Fan YANG, Gaisheng LIU, Qingsong CHEN

“…Current research on the thyroid mainly focuses on the impacts of lifestyle factors on thyroid dysfunction, while less attention is paid to the factors affecting thyroid hormone levels, especially occupational hazards, which warrants further investigation. …”
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Narrative Review on the Management of Neck of Femur Fractures in People Living with HIV: Challenges, Complications, and Long-Term Outcomes by Yashar Mashayekhi, Chibuchi Amadi-Livingstone, Abdulmalik Timamy, Mohammed Eish, Ahmed Attia, Maria Panourgia, Dushyant Mital, Oliver Pearce, Mohamed H. Ahmed

“…Additionally, HIV-related immune dysfunction, cART-induced osteoporosis, and perioperative infection risks further pose challenges in ongoing surgical management. …”
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Incidence of severe maternal outcomes following armed conflict in East Gojjam zone, Amhara region, Ethiopia: using the sub-Saharan Africa maternal near-miss criteria by Tirusew Nigussie Kebede, Kidist Ayalew Abebe, Ambachew Getahun Malede, Abinet Sisay, Ayenew Yirdie, Worku Taye, Tebabere Moltot Kitaw, Bezawit Melak Fente, Mesfin Tadese, Tesfanesh Lemma Demisse, Mulualem Silesh, Solomon Hailemeskel Beshah, Getaneh Dejen Tiche, Michael Amera Tizazu, Moges Sisay Chekole, Birhan Tsegaw Taye

“…Over 80% of women with SMO showed evidence of organ dysfunction upon arrival or within 12 h of hospitalization. …”
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The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency by Prabha Chandrasekaran, Máté Krausz, Yu Han, Noriko Mitsuiki, Annemarie Gabrysch, Christina Nöltner, Michele Proietti, Theo Heller, Caroline Grou, Virginie Calderon, Poorani Subramanian, Drew R. Jones, Yik Siu, Clayton Deming, Sean Conlan, Steven M. Holland, Julia A. Segre, Gulbu Uzel, Bodo Grimbacher, Emilia Liana Falcone

“…While regulatory T-cell dysfunction remains central to CTLA4-D immunopathogenesis, mechanisms driving disease severity and intestinal pathology are unknown but likely involve intestinal dysbiosis. …”
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Analysis of prognosis of neurological sequelae in children with carbon monoxide poisoning by Tuoying Wen, Jinghong Liang, Yulan Wei, Weijun Lin, Liya Pan

“…So, for children who were unconscious for more than one day or presented characteristic changes in cranial imaging, long-term follow-up should be carried out to determine whether delayed encephalopathy or subsequent cognitive impairment occurs.…”
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Performing the HINTS-exam using a mixed-reality head-mounted display in patients with acute vestibular syndrome: a feasibility study by Nadia Sadok, Gijs Luijten, Gijs Luijten, Gijs Luijten, Fin H. Bahnsen, Christina Gsaxner, Lorenz Peters, Theda Eichler, Theresa Rombach, Stephan Lang, Sameh Khattab, Jens Kleesiek, Jens Kleesiek, Jens Kleesiek, Jens Kleesiek, Jens Kleesiek, Dagny Holle, Moritz Meyer, Jan Egger, Jan Egger, Jan Egger, Jan Egger, Jan Egger

“…The feasibility study included 21 healthy subjects, seven patients with acute peripheral vestibular dysfunction and two stroke patients. Eye gaze, head position, and orientation were captured using a MR-OST-HMD and an in-house developed application designed to simulate the HINTS-Exam. …”
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High‐Density Lipoprotein‐Associated Cholesterol Abnormalities in a Clinical Outcomes Study of Dysferlin‐Deficient Limb–Girdle Muscular Dystrophy Type R2 by Zoe White, Laura Rufibach, Heather Gordish Dressman, Heather Hilsden, Dan Cox, Simone Spuler, John W. Day, Kristi J. Jones, Diana X. Bharucha‐Goebel, Emmanuelle Salort‐Campana, Alan Pestronk, Maggie C. Walter, Carmen Paradas, Tanya Stojkovic, Madoka Mori‐Yoshimura, Elena Bravver, Jordi Diaz‐Manera, Elena Pegoraro, Jerry R. Mendell, the Jain COS Consortium, Volker Straub, Pascal Bernatchez

“…It leads to slow proximal and distal muscle weakening that generally results in loss of ambulation around early adulthood but without the lethal cardiorespiratory dysfunction observed in the more severe Duchenne MD. …”
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Broad repetitive transcranial magnetic stimulation (rTMS) of the precuneus in Alzheimer's disease: A rationale and study design by Michael K. Leuchter, Hanadi A. Oughli, Kelly A. Durbin, Nicholas J. Jackson, David Elashoff, Timothy S. Chang, Juliana Corlier, Doan Ngo, Cole Matthews, Darice Wong, Brent L. Fogel, Gal Bitan, Andrew F. Leuchter, Keith Vossel, Nanthia Suthana

“…Abstract INTRODUCTION Brain network dysfunction, particularly within the default mode network (DMN), is an increasingly apparent contributor to the clinical progression of Alzheimer's disease (AD). …”
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Cardiofaciocutaneous syndrome and immunodeficiency: data from an international multicenter cohort by Benedetta Elena Di Majo, Benedetta Elena Di Majo, Chiara Leoni, Eleonora Cartisano, Eleonora Cartisano, Chiara Fossati, Germana Viscogliosi, Valentina Trevisan, Lucia Pia Bruno, Francesca Conti, Mattia Moratti, Emilia Monaco, Donato Rigante, Donato Rigante, Beatrice Rivalta, Beatrice Rivalta, Caterina Cancrini, Caterina Cancrini, Aleksandra Szczawińska-Popłonyk, Aleksander Jamsheer, Aleksander Jamsheer, Monika Obara-Moszyńska, Viktoria Zakharova, Anna Shcherbina, Julija Rodina, Beyhan Tüysüz, Saumya Shekhar Jamuar, Saumya Shekhar Jamuar, Jiin Ying Lim, Jeannette Goh, Anna Cereda, Teresa Agovino, Ilaria Contaldo, Maria Luigia Gambardella, Adriana Cristina Balduzzi, Adriana Cristina Balduzzi, Alessia Cherubino, Giovanni Antonio Marrocco, Silvia Bellesi, Valentina Carusi, Gabriele Rumi, Andrea Biondi, Giuseppe Zampino, Giuseppe Zampino, Francesco Saettini, Francesco Saettini

“…Given these findings, routine immunological assessment should be considered in CFCS patients to facilitate early detection and appropriate management of immune dysfunction.…”
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Leprosy neuropathy: clinical presentations by Osvaldo J M Nascimento

“…Arthritic presentation is occasionally seen, usually misdiagnosed as rheumatoid arthritis. Attention should be given to autonomic dysfunctions in leprosy. …”
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Autosomal dominant HK1-related neurodevelopmental disorder with visual defects and brain anomalies (NEDVIBA): An emerging mitochondrial disorder by Bobby G. Ng, Erik A. Eklund, Jill A. Rosenfeld, Abdallah F. Elias, Aya Abu-El-Haija, Celine Bris, Magalie Barth, Jong-Hee Chae, Murim Choi, Holly A. Dubbs, Carl Fratter, Nicola Foulds, Candace Gamble, Ralitza H. Gavrilova, Jaclyn Haven, Trevor L. Hoffman, Jill V. Hunter, Austin Larson, Timothy Edward Lotze, Pilar Magoulas, Emily C. Magness, Debra M. Bootin, Eric D. Marsh, Victoria Nesbitt, Matthew T. Pastore, Joanna Poulton, Shamima Rahman, Fernando Scaglia, Chaya Murali, Jennifer Posey, Joshua Rotenberg, Betsy Schmalz, Deepali N. Shinde, Zöe Powis, Rivka Sukenik-Halevy, Kristen V. Truxal, Tami Uster, Matheus Vernet Machado Bressan Wilke, Erik Klee, Hyewon Woo, Donald Younkin, Jianhua Zhao, Jorge Granadillo, Seema Lalani, David Chitayat, Wendy K. Chung, Hudson H. Freeze, Volkan Okur

“…In terms of genotype-phenotype correlation, we find that all individuals carrying a missense variant at the threonine 457 residue have severe clinical features. Conclusion: HK1 should be included in mitochondrial disorder gene sequencing panels.…”
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VULVAR AND VAGINAL GRAFT VERSUS HOST DISEASE IN A PATIENT WITH CHRONIC PHASE CHRONIC MYELOID LEUKEMIA AFTER ALLOGENEIC STEM CELL TRANSPLANTATION by Esra Pirinççi, M. Orhan Ayyıldız, Abdullah Karakuş, Reyhan Gündüz

“…Incidence and severity of genital GVHD in women should be included in GVHD intervention studies.…”
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Comparison of Serenoa repens, lycopene, and selenium versus dutasteride for the treatment of LUTS/BPH: an Italian multicenter case-control prospective study (COMP study) by Giuseppe Morgia, Arturo Lo Giudice, Sebastiano Cimino, Giulio Reale, Gaetano Larganà, Enza La Manna, Massimo Madonia, Alessandro Tedde, Francesco Santaniello, Giuseppe Vespasiani, Stefano Zaganelli, Salvatore Arnone, Nicola Cruciano, Maurizio Carrino, Francesco Persico, Carlo Terrone, Rafaela Malinaric, Andrea Minervini, Marco Carini, Giorgio Ivan Russo

“…The main outcome measures included International Prostatic Symptoms Score (IPSS) and IPSS quality-of -life (QoL), International Index of Erectile Function (IIEF-5), Qmax measured at uroflowmetry and the Male Sexual Health Questionnaire (MSHQ).ResultsWe have observed increasing of Qmax of 2 points in group A and 2,5 points group B; IPSS has been reduced of 4 points in group A and 4,5 points in group B; IIEF-5 didn’t change in group A and it has been reduced in group B by -1; regarding the MSHQ, only the item MSHQ-Satisfaction has changed in group A: -1, in group B MSHQ was reduced by -2 points in ED, by -5 points in EJ, by -2,5 points in Satisfaction, by -0,5 points in Intercourse, by -3,2 points in Desire.ConclusionsSeR-Se-Ly could be a valid alternative to dutasteride, providing comparable effects on symptoms related to LUTS/BPH and avoiding sexual dysfunctions. SeR-Se-Ly should not be substituted for dutasteride in those patients for whom prostate volume reduction is desired.…”
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Randomised trial comparing weight loss through lifestyle and GLP-1 receptor agonist therapy in people with MASLD by Ahmad Moolla, Toryn Poolman, Nantia Othonos, Jiawen Dong, Kieran Smith, Thomas Cornfield, Sarah White, David W. Ray, Sofia Mouchti, Ferenc E. Mózes, Helena Thomaides-Brears, Stefan Neubauer, Jeremy F. Cobbold, Leanne Hodson, Jeremy W. Tomlinson

“…Background & Aims: Glucagon-like peptide 1 receptor agonist (GLP-1RA) therapies deliver histological benefit in people with metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line models by Fangfang Zhang, Tatjana Dorn, Barbara Gnutti, Yair Anikster, Sarah Kuebler, Rebecca Ahrens-Nicklas, Rachel Gosselin, Shamima Rahman, Ronen Durst, Enrica Zanuttigh, Miriam A. Güra, Christine M. Poch, Anna B. Meier, Karl-Ludwig Laugwitz, Hans-Joachim Schüller, Ana C. Messias, Ody C. Sibon, Dario Finazzi, Alyssa Rippert, Dong Li, Kristen Truxal, Deipanjan Nandi, Brent C. Lampert, Mildrid Yeo, Alice Gardham, Batel Nissan, Smadar Horowitz Cederboim, Alessandra Moretti, Arcangela Iuso

“…These findings underscore the importance of timely diagnosis and treatment in PPCS DD. Future research should focus on optimizing pantethine supplementation and exploring additional therapies to enhance CoA levels and cardiac function in affected individuals.…”
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Rare neurological and neuropsychiatric manifestations of scrub typhus: a case series of 10 cases by Ritwik Ghosh, Arpan Mandal, Moisés León-Ruiz, Dipayan Roy, Shambaditya Das, Souvik Dubey, Julián Benito-León

“…This otherwise curable disease may result in multi-organ dysfunction syndrome and death if the diagnosis is delayed. …”
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Modified cavocavostomy technique for deceased donor liver transplantation by S. E. Voskanyan, A. I. Artemyev, A. I. Sushkov, K. K. Gubarev, D. S. Svetlakova, M. V. Popov, V. S. Rudakov, A. N. Bashkov, E. V. Naydenov, M. Muktarzhan

“…The volumes of intraoperatively transfused blood components were, respectively: packed red cells 630 ml (interquartile range: 0–1280 ml) and 600 ml (interquartile range: 0–910 ml), p=0.262; blood reinfusion 770 ml (interquartile range: 360–1200 ml) and 700 ml (interquartile range: 0–1200 ml), p=0.370; fresh frozen plasma 2670 ml (interquartile range: 2200 and 3200 ml) and 2240 ml (interquartile range: 1880–2900 ml), p=0.087.When using classic caval reconstruction technique, the proportion of grafts with early dysfunction was higher: 44% vs. 17% (p=0.011), due to the higher rate of retransplantations in this group. …”
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Gender-Dependent Modulation of Alzheimer’s Disease by Brain Ischemia. Comment on Lohkamp et al. Sex-Specific Adaptations in Alzheimer’s Disease and Ischemic Stroke: A Longitudinal... by Ryszard Pluta

“…Therefore, future studies should consider, for example, studies using single-cell technologies that can provide insight into the timing and sequence of cellular dysfunctions across sexes and analyze the continuity of changes over time, starting from short-term observations of a few days and ending with long-term observations of a year or more, to assess the continuity and differentiation of changes.…”
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