The relationship between social isolation and cognitive function in older patients with chronic obstructive pulmonary disease: a latent profile analysis by Minghua Han, Hongxia Wu, Huize Xu, Jian Zhao, Zhongwen Chang, Qian Zhao

“…Conclusion The findings reveal a significant association between social isolation patterns and cognitive dysfunction risk in older COPD patients. Nurses and healthcare providers should prioritize screening for cognitive impairment in the “High Social Isolation-Interaction Deficiency Group”, as this subgroup exhibits the highest prevalence of cognitive deficits. …”
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The Effects of Glucagon‐Like Peptide‐1 Receptor Agonists on Mitochondrial Function Within Skeletal Muscle: A Systematic Review by Victoria J. Old, Melanie J. Davies, Dimitris Papamargaritis, Pratik Choudhary, Emma L. Watson

“…Data are very limited and solely presented in animal and in vitro models. Future studies should be conducted in human populations in order to begin to understand the effect of GLP‐1 RAs and GLP‐1‐based therapies on human skeletal muscle mitochondria.…”
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Integrative diagnostic criterion for evaluation of COVID-19 severity and the risk of post-COVID syndrome by I. V. Nesterova, M. G. Atazhakhova, V. A. Matushkina, Yu. V. Teterin, V. N. Gorodin, G. A. Chudilova

“…A significant decrease in IDC indicates the persisting hyper-activation of NG and a need for targeted immunotherapy aimed at modulating the NG dysfunction.…”
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Immune Checkpoint Inhibitors and Cardiovascular Adverse Events by Maria Luisa De Perna, Elia Rigamonti, Raffaele Zannoni, Vittoria Espeli, Giorgio Moschovitis

“…In hemodynamically unstable patients, treatment with high‐dose steroids should be initiated (intravenous methylprednisolone 1000 or 1250 mg oral methylprednisolone during 4 days). …”
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Prospective longitudinal assessment of Albumin-to-Creatinine ratio (ACR) in a clinical cohort of people living with HIV in Gaborone, Botswana by Mosepele Mosepele, Kago Kebotsamang, Ponego Ponatshego, Kesaobaka Molebatsi, Thato Moshomo, Lucky Mokgatlhe, Shahin Lockman, Robert Gross, Joseph Jarvis, Shabbar Jaffar, Duolao Wang

“…Abstract Background People living with HIV (PLWH) in sub-Saharan Africa are vulnerable to end organ dysfunction such as albuminuria, which is associated with an increased risk of cardiovascular and renal events. …”
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Somatostatin and its receptors involvement in sevoflurane-induced neurotoxicity: a narrative review by Yixuan Niu, Jinnan Xu, Yanyong Cheng, Linhong Zhong, Jing Wang, Yanan Jiang, Chen Wang, Zhengjie Miao, Fan Wang, Chuanyu Qi, Tiannan Chen, Yi Gao, Hong Jiang, Jia Yan

“…Mechanistically, SSTR4 activation exacerbates synaptic dysfunction through adenylate cyclase (AC) inhibition, reducing cAMP levels and diminishing AMPA receptor phosphorylation. …”
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Are We Getting Better?: Ongoing Challenges of Atrioventricular Valve Repair in Children With Single Ventricle Physiology by Sachiko Kadowaki, Maelys Venet, Teerapong Tocharoenchok, Kok Hooi Yap, Chun‐Po Steve Fan, Yasmin Zahiri, Mimi X. Deng, Olivier Villemain, Alejandro Floh, David J. Barron, Osami Honjo

“…Alternative treatment strategies should be considered for this high‐risk subgroup.…”
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Primary Prevention Strategy for Non-Communicable Diseases (NCDs) and Their Risk Factors: The Role of Intestinal Microbiota by Itzel Ivonn López-Tenorio, Óscar Rodrigo Aguilar-Villegas, Yoshua Espinoza-Palacios, Lorena Segura-Real, Berenice Peña-Aparicio, Amedeo Amedei, María Magdalena Aguirre-García

“…Therefore, primary healthcare must be both exclusive and of the highest quality, ensuring comprehensive care. The primary goal should be to improve quality of life with a focus on patients, families, and communities, as most of these diseases can be prevented and controlled, although not cured. …”
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Economic evaluations of pharmacological and non-pharmacological interventions for delirium: A systematic review and meta-analysis by Md Parvez Mosharaf, Khorshed Alam, Jeff Gow, Rashidul Alam Mahumud

“…Background: Delirium, a prevalent cognitive dysfunction in older adults, particularly in hospital and surgical settings, significantly increases patient morbidity, mortality, and healthcare costs. …”
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HISTOGENETIC ASPECTS OF PNEUMOFIBROSIS DURING CONIOTIC CHANGES IN KUZBASS MINERS by Олег Иванович Бондарев, Сергей Николаевич Филимонов

“…Intracellular changes occurring in PC should serve as a foundation for further in-depth study of complex pathogenetic aspects in medicine.…”
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Pulmonary Hemorrhage in Premature Infants: Pathophysiology, Risk Factors and Clinical Management by Sariya Sahussarungsi, Anie Lapointe, Andréanne Villeneuve, Audrey Hebert, Nina Nouraeyan, Satyan Lakshminrusimha, Yogen Singh, Christine Sabapathy, Tiscar Cavallé-Garrido, Guilherme Sant’Anna, Gabriel Altit

“…Despite advancements in neonatal care, PH remains a major contributor to neonatal mortality and long-term neurodevelopmental impairment. Future research should focus on individualized risk stratification, early diagnostic tools, and optimized treatment protocols to improve outcomes. …”
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Impact of Polystyrene Microplastics on Human Sperm Functionality: An In Vitro Study of Cytotoxicity, Genotoxicity and Fertility-Related Genes Expression by Filomena Mottola, Maria Carannante, Ilaria Palmieri, Lorenzo Ibello, Luigi Montano, Mariaceleste Pezzullo, Nicola Mosca, Nicoletta Potenza, Lucia Rocco

“…Possible environmental and working exposure to pollutants should be considered during the counselling for male infertility.…”
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Mapping the future: bibliometric insights into ferroptosis and diabetic nephropathy by Tangwen Wei, Yang Qin, Xiaohui Lin, Xiujuan Wang, Suyi Chen, Xia Chen, Nan Yan, Xinyi Wei, Zhichang Zhang, Bing Wei

“…Preclinical agents, including ginkgolide B (GB) and dapagliflozin, effectively restored iron homeostasis and attenuated oxidative damage.ConclusionFerroptosis is a promising therapeutic target for DN, yet its clinical translation remains in its infancy. Future efforts should prioritize large-scale clinical trials, single-cell mechanistic profiling, and interdisciplinary integration to bridge molecular insights with precision therapies. …”
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New opportunities for preclinical diagnostics of antitumor therapy cardiotoxicity: results of an observational study by Yu. A. Vasyuk, D. A. Vyzhigin, E. Y. Shupenina, E. O. Novosel, E. A. Ulyanova

“…During the observation of oncological patients receiving chemo- and targeted therapy, it was found that a specific pattern, previously not described, was revealed in patients with developed systolic dysfunction upon visual assessment of the longitudinal strain of the LV. …”
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СORONAVIRUS INFECTION WITH AN OBESITY by S. N. Ionov, S. S. Saidov, O. V. Abanina, M. Yu. Petrov, E. S. Klimova

“…SARS infection has been found to cause hyperglycemia in some patients due to dysfunction of the islets of the pancreas as a result of a viral attack. …”
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An Overview of Oxidative Stress in Sex Chromosome Aneuploidies in Pediatric Populations by Roberto Paparella, Fabiola Panvino, Francesca Tarani, Benedetto D’Agostino, Lucia Leonardi, Giampiero Ferraguti, Sabrina Venditti, Fiorenza Colloridi, Ida Pucarelli, Luigi Tarani, Marco Fiore

“…TS is marked by estrogen deficiency, cardiovascular anomalies, and metabolic dysfunction, all linked to heightened oxidative stress. …”
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Fear of hypoglycemia: a key predictor of sleep quality among the diabetic population by Hafiz Rashid Hussain, Nabeel Ahmed, Muhammad Waseem Akram, Faisal Gulzar, Jawad Akbar Khan, Muhammad Asad, Sana Tahseen, Tanveer Ahmed, Abdul Malik, Suhail Akhtar, Ayesha Shahid, Mah Noor, Maryam Pervaiz, Muneeb Ur Rahman

“…Healthcare providers should prioritize patient education targeting common FOH concerns and assess patients with disturbed sleep for elevated FOH levels, as it may contribute to sleep disturbances.…”
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Vibration Energy Color Doppler Imaging (VECDI) in Evaluating the Effect of Screw Fixation on Sacroiliac Joint Stiffness: A Prospective Pilot Study by Caleb Gottlich, Thomas Githens, Alex Drusch, Neil Jain, Cyrus Caroom, Phillip S. Sizer

“…Direct inferences regarding VECDI’s exact sensitivity to SIJ dysfunction cannot be concluded from our investigation due to small sample sizes. …”
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SUCCESSFUL APPLICATION OF PERIPHERAL VENO-ARTERIAL EXTRACORPOREAL MEMBRANE OXYGENATION FOR CARDIAC ALLOGRAFT ANTIBODY-MEDIATED REJECTION WITH SEVERE HEMODYNAMIC COMPROMISE by V. N. Poptsov, E. A. Spirina

“…Patient was discharged from ICU on the 2nd and 26th day after VA ECMO in stable clinical status. Conclusion. VA ECMO should be crucial component of treatment of cardiac allogaft antibody-mediated rejection with severe hemodynamic compromise.…”
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Viral infections and immune modulation in bladder cancer: implications for immunotherapy by Lívia Bitencourt Pascoal, Mehrsa Jalalizadeh, Gabriela Barbosa, Andrea Nazare Monteiro Rangel da Silva, Maria Alice Freitas Queiroz, Ekaterina Laukhtina, Shahrokh F. Shariat, Alessandra Gambero, Leonardo O. Reis

“…This review discusses the interplay between viral antigenic load, immune dysfunction, and tumor microenvironment remodeling, highlighting their potential impact on immunotherapies. …”
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