Feasibility of three dimensional and strain transthoracic echocardiography in a single-centre dedicated NHS cardio-oncology clinic by Patrick O’Driscoll, David Gent, Liam Corbett, Rod Stables, Rebecca Dobson

“…Recommendations highlight that either two-dimensional (2D) or three-dimensional (3D) left ventricular ejection fraction (LVEF), alongside global longitudinal strain (GLS) should be routinely performed for surveillance of patients at risk of cancer therapy-related cardiac dysfunction (CTRCD). …”
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Combined resection of the transpancreatic common hepatic artery preserving the gastric arterial arcade without arterial reconstruction in hepatopancreatoduodenectomy: a case report by Takashi Miyata, Yusuke Yamamoto, Teiichi Sugiura, Yukiyasu Okamura, Takaaki Ito, Ryo Ashida, Sunao Uemura, Yoshiyasu Kato, Katsuhisa Ohgi, Atsushi Kohga, Tsuneyuki Uchida, Shusei Sano, Katsuhiko Uesaka

“…Conclusions When planning PD, including hepatopancreatoduodenectomy, for patients with a tp-CHA, surgeons should simulate various situations for maintaining the hepatic arterial flow. …”
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Cerebellar hemorrhage in patients treated with edoxaban for portal vein thrombosis after hepatobiliary surgery: a report of two cases by Hiroya Iida, Toru Miyake, Masaji Tani, Takuya Tanaka, Kayo Kawakami, Yoshihiro Ikuno, Ryoichi Mandai, Tomoharu Shimizu

“…The monitoring of hepatic dysfunction and decision for continuation of drug may be required during edoxaban use for PVT, especially after hepatobiliary surgery.…”
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Cardiovascular function shows early impairment in asymptomatic adolescents diagnosed with type 1 diabetes mellitus: an ultrasound-derived myocardial work study by Martina Ghirardo, Martina Ghirardo, Irene Cattapan, Irene Cattapan, Jolanda Sabatino, Jolanda Sabatino, Alice Pozza, Alice Pozza, Jennifer Fumanelli, Jennifer Fumanelli, Martina Avesani, Joaquin Gutierrez De Rubalcava Doblas, Carlo Moretti, Biagio Castaldi, Giovanni Di Salvo

“…BackgroundCardiac dysfunction and endothelial damage are known complications of type 1 diabetes mellitus (T1D) mainly affecting adults. …”
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Issues of intensive care and liver transplantation tactics in fulminant liver failure by L. U. Agumava, V. A. Gulyaev, K. N. Lutsyk, O. D. Olisov, R. B. Akhmetshin, K. M. Magomedov, B. I. Kazymov, A. R. Akhmedov, K. F. Alekberov, B. I. Yaremin, M. S. Novruzbekov

“…Patients with acute liver failure should be treated at a liver transplant center whenever possible. …”
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Status quo and influencing factors of cancer-related cognitive impairment in patients with bone metastasis (骨转移瘤患者癌症相关认知功能障碍现状及影响因素分析)... by ZHAO Lingling (赵玲玲), ZHANG Xiaojuan (张晓娟), CHEN Ping (陈平), LU Xin (鲁鑫)

“…While focusing on the improvement of physical function symptoms, attention should be paid to the screening and intervention of cognitive dysfunction. …”
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A correlation analysis of Lee’s grade CKD stage and hypertension in IgA nephropathy by LIAO Ying, HE Yong-cheng, HU Hao-fei, QI Dong-li

“…Objective To analyze the correlation of Lee’s grade CKD stage and hypertension in IgA nephropathy in order to provide the basis for guiding diagnosis and treatment of primary IgA nephropathy.Methods A total of 430 patients with primary IgA nephropathy diagnosed by renal biopsy in Shenzhen 2nd People’s Hospital were enrolled as the research objects.We analyzed their clinical data,including sex,age,weight,blood pressure,serum albumin,creatinine,uric acid,blood lipids(total cholesterol,triglyceride,low density lipoprotein cholesterol,high density lipoprotein cholesterol),24-h urinary protein and renal pathology Lee’s grade.The glomerular filtration rate was estimated by serum creatinine levels.These patients were divided into CKD stage 1-5 according to the estimated glomerular filtration rate.At the same time,these patients were divided into hypertension group(including hypertension grade 1,2 and 3) and non-hypertension group according to the level of blood pressure.The correlation between hypertension and the clinical data,renal pathology Lee’s grade,CKD stage was analyzed.Results Among 430 IgA nephropathy patients,the male:female ratio was1.05:1,the age was 13 to 72 years old(mean 34.5 ± 9.4 years),and incidence peak age was 21-30 years old.Age was older and weight was heavier in hypertension group than in non-hypertension group(P<0.05 for both).The prevalence of hypertension in these group data was 46.7%.In hypertension group,there were 42 patients with hypertension grade 1(9.8%),57 patients with hypertension grade 2(13.2%),and 102 patients with hypertension grade 3(23.7%),respectively.The age was older,body weight was heavier,and 24-h urinary protein,serum creatinine,uric acid,total cholesterol,triglyceride and low density lipoprotein cholesterol were higher,and the serum high density lipoprotein cholesterol was lower in hypertension group than in non-hypertension group(P<0.05 for all).There were 66,63 and 44 cases of renal pathology Lee’s grade,Ⅳ and Ⅴ,respectively in hypertension group.Spearman correlation analysis showed that hypertension was correlated with renal pathology Lee’s grade(r=0.394,P=0.0000).There were 60,36 and 11 cases of CKD stage 3-5 respectively in hypertension group.Spearman correlation analysis showed that hypertension was correlated with CKD stage(r=0.477,P=0.0000).Multiple factors Logistic regression analysis showed that serum creatinine,Lee’s grade and CKD stage were correlated with IgA nephropathy with hypertension.Conclusions The prevalence of IgA nephropathy with hypertension was higher,and its CKD stage and renal pathology Lee’s grade were more severe correspondingly.So we should strengthen the control of blood pressure to delay the progress of renal dysfunction.…”
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Evaluation of risk factors for poor wound healing after cesarean delivery in patients with gestational diabetes mellitus: a retrospective study by Yan Liu, Ye Wang, Shao-Hua Gao, Hui Wu, Chun-Yu Zhang, Jia-Li Yao, Pei-Xia Cai

“…Candida infection also showed a statistical association but was based on limited case numbers and should be interpreted cautiously. Targeted perioperative strategies may help reduce PWH risk in this population.…”
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The role of triglycerides in predicting new-onset arthritis in the general population over 45 years old: evidence from the China health and retirement longitudinal study by Weiwei Ma, Honggu Chen, Jing Deng, Qipeng Yuan, Huanan Li, Huanan Li

“…Due to its strong association with chronic pain and dysfunction, arthritis has become an important challenge in public health. …”
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Clinical and Imaging Characteristics of Patients with Cervical Compressive Myelopathy Presenting with Unilateral Motor Deficits by Masatsune Sato, Hisanori Mihara, Hyonmin Choe, Takanori Niimura, Yuji Kawashima, Yutaka Inaba

“…Future research to improve treatment outcomes should focus on spinal cord circulation assessment using advanced imaging techniques.…”
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Plasminogen as a Marker for Assessing Thrombotic Risk During Hepatitis in Cameroon: Case–Control Study by Romaric De Manfouo Tuono, Marius Mbiandjeu Tchoumke, Winy Asdrid Djoumeni Tepe, Winnie Ketcha Jeuta, Simon Ngamli Fewou

“…Importantly, hepatic dysfunction that arises from hepatitis may perturb the clotting process. …”
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Pathophysiological mechanisms and clinical consequences of exposure to new psychoactive substances (“salts”) on a newborn by Elena V. Loshkova, Ivan V. Doroshenko, Tatiana S. Liulka, Anatoly I. Khavkin, Elena I. Kondratieva, Nuriniso D. Odinaeva, Yulia S. Rafikova, Viktor A. Zhelev, Andrey L. Solnyshko, Evgeniy V. Mikhalev, Sergey P. Ermolenko, Ivan R. Grishkevich, Nikolay E.  Melnikov, Anton A. Bohunetsky, Elizaveta I. Makarevich

“…In addition, it is necessary to pay attention to the fact that the use of NPAS is of great social and economic significance, the description of such clinical observations, as well as in vitro studies, is relevant, and the expansion of ideas about the short-term and long-term negative consequences of the use of NPAS should serve as an initiating stage for the development of rehabilitation strategies for these patients…”
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Relevance of anxiety in clinical practice of Guillain-Barré syndrome: a cohort study by Raphaël Porcher, Djillali Annane, Andrea Polito, Tarek Sharshar, Takoua Merhbene, Morgane Blanc, Marion Antona, Marie-Christine Durand, Diane Friedman, David Orlikowski, Marie-Hélène Marcadet

“…Uncertainty was independently associated with subsequent MV.Conclusions Early management of patients with GBS should evaluate anxiety and assess its causes both to adjust psychological support and to anticipate subsequent deterioration.…”
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Herbal medicine evaluation for reimbursement-based facial palsy (HERB-FP): a retrospective analysis using Korean health insurance claim data 2020–2024 by Soo-Dam Kim, Man Young Park, Eunbyul Cho, Jiyun Cha, Changsop Yang, Sungha Kim

“…As the second-phase program expands in scope and duration, further research should explore its long-term clinical and economic outcomes to guide evidence-based healthcare policy development.…”
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The Utility of Maternal Blood S100B in Women with Suspected or Established Preeclampsia—A Systematic Review by Grigorios Karampas, Athanasios Tzelepis, Sevasti Koulouraki, Despoina Lykou, Dimitra Metallinou, Lena Erlandsson, Konstantinos Panoulis, Nikolaos Vlahos, Stefan Rocco Hansson, Makarios Eleftheriades

“…Still, additional studies should be conducted in order to establish a standard method of measurement and solidify its clinical use in preeclampsia management, providing individualized care in order to improve perinatal outcomes and provide personalized follow-up postpartum.…”
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The role of statins during pregnancy on maternal risk of preeclampsia: a systematic review and meta-analysis by Pantea Khalili, Zixing Zhong, Yanqing Peng

“…While subgroup findings suggest that early initiation may be associated with reduced risk, these observations should be interpreted with caution and require confirmation in future high-quality trials. …”
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Association between perceived stress and MAFLD partially mediated by smoking and drinking by Yan Gong, Shengshu Wang, Jianan Jiang, Qiang Zeng, Weimin Wang, Yansong Zheng, Wenping Lv

“…Public health strategies should target both smoking and drinking especially in high-stress populations, given their compounded risk for MAFLD.…”
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Postcholecystectomy syndrome: the modern approach: resolution of Advisory council by V. T. Ivashkin, A. V. Okhlobystin, D. S. Bordin, E. Ya. Seleznyova, Yu. A. Kucheryavy, Ye. V. Bystrovskaya, O. C. Vasnev, M. F. Osipenko, G. H. Musayev, Yu. O. Shulpekova

“…Follow-up program for the patient of the cholecystectomy should include regular assessment of clinical symptoms for duly diagnostics of acute and/or severe complications and associated diseases, that may require surgical treatment. …”
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Prognostic significance of PD‐L2 expression in patients with oral squamous cell carcinoma—A comparison to the PD‐L1 expression profile by Manuel Weber, Falk Wehrhan, Christoph Baran, Abbas Agaimy, Maike Büttner‐Herold, Marco Kesting, Jutta Ries

“…Conclusion Peripheral blood PD‐L1 expression might be a prognostic marker for OSCC patients and a possible parameter to monitor immune dysfunction in malign diseases. In the peripheral blood, PD‐L1 might be more relevant for immune tolerance than PD‐L2. …”
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SURGICAL TREATMENT CHOICE FOR PATIENTS WITH NON-RESECTABLE PANCREATIC HEAD CANCER by Borys H. Bezrodnyi, Ihor V. Kolosovych, Yevhenii O. Nesteruk

“…With a Karnofsky index <80, it is advisable to perform stenting of the common bile duct with SEMS, with a Karnofsky index >80, double biliodigestive and prophylactic gastrodigestive bypass surgery should be performed. When multiorgan dysfunction and cholangitis develop against the obstructive jaundice, the treatment consists of two stages, the first – transpapillary biliary drainage with plastic stents, the second – elective surgical intervention.…”
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