A case of familial recurrent 17q12 microdeletion syndrome presenting with severe diabetic ketoacidosis by Can Aydın, Eylem Kıral, Ezgi Susam, Aslı Kavaz Tufan, Coskun Yarar, Nuran Çetin, Sinem Kocagil, Birgül Kırel

“…The genetic analysis of the patient and her mother revealed a loss of 1.6 megabases in chromosome 17q12. Conclusions. MODY5 should be kept in mind in patients with diabetes who present with extra pancreatic findings, especially with renal cystic disease, more over, a genetic analysis including the study of 17q12MD should be carried out in patients who present with additional neuropsychiatric findings. …”
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Determination of Factors Affecting Sleep Quality in Postoperative Patients and Improvement of Correctible Causes by Ayşegül Özgök, Gökçe Selçuk Sert, Dilek Öztürk Kazancı

“…We think that sleep has a very important place in accelerating the recovery process of postoperative patients and that sleep disorders should be questioned better and that postoperative patients with sleep disorders should definitely seek psychological and medical help.…”
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Cardiovascular toxicity in testicular germ cell tumor survivors by Zuzana Orszaghova, Beata Mladosievicova, Michal Mego, Michal Chovanec

“…Cardiovascular risk assessment and prevention should be central components, especially in survivors treated with cisplatin-based chemotherapy. …”
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The contribution of childhood trauma to irritability symptoms by Lana Ruvolo Grasser, Ruiyu Yang, Melissa A. Brotman, Jillian Lee Wiggins

“…Early life experiences should be considered in assessment and treatment of youth with clinically impairing irritability. …”
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The role of anticoagulants in the treatment of community-acquired pneumonia in patients combined with coronavirus infection by I. M. Fushtei, V. O. Mochonyi, O. V. Soloviov

“…Anticoagulant selection should take into consideration not only biochemical and coagulation parameters, such as elevated D-dimer, fibrinogen, and low antithrombin, which are the targets of this therapy. …”
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Fatal case of EBV induced hemophagocytic lymphohistiocytosis (HLH), presenting with acute abdomen by Gina Rami Salama Ibrahim Abdelmesih

“…Physicians needs to be aware of its causes and pathogenesis for early recognition and appropriate treatment. Multiple organ dysfunction can rapidly develop. No documented prognostic indicator can alarm the physician of the developing HLH and therefore HLH should be considered in all critically ill patients. …”
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Managing Aminotransferase Elevations in Patients with Friedreich Ataxia Treated with Omaveloxolone: A Review and Expert Opinion on Use Considerations by Susan Perlman, Mathieu Anheim, Sylvia Boesch, James H. Lewis, David R. Lynch

“…Per label, omaveloxolone should be temporarily discontinued if aminotransferases increase to > 5 × the upper limit of normal (ULN) or > 3 × ULN with other evidence of liver dysfunction. …”
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Two Cases of Late Diagnosis Pituitary Stalk Interruption Syndrome and Literature Review by Alkhalifa M, Alsalman Z, Al Elq A, Al-khadrawi Z, Radwan H

“…To the best of our knowledge, this is the first case series of such late diagnosis PSIS from Saudi Arabia.Conclusion: The key message of this paper is that rare etiologies such as PSIS should be kept in mind, especially for young patients presenting with clinical evidence of pituitary hormonal deficiencies, and MRI should be considered to confirm diagnosis. …”
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The Role of Ferritin in Assessing COVID-19 Severity by Yu. S. Polushin, I. V. Shlyk, E. G. Gavrilova, E. V. Parshin, A. M. Ginzburg

“…The persistent increase of ferritin level in blood during 4-6 days of stay in ICU should be considered as a reason to intensify anticytokine therapy.…”
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Recovering Voiding and Sex Function in a Patient with Chronic Complete Spinal Cord Injury by Olfactory Ensheathing Cell Transplantation by Di Chen, Haitao Xi, Ke Tan, Hongyun Huang

“…In the future, the deep mechanisms of why he got positive results, but other patients with similar condition did not get so much benefits from OEC transplantation should be explored.…”
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Seasonal Influence on the Impact of Human Chorionic Gonadotropin (hCG) on Testicular Haemodynamics and Hormonal Responses in Canines: A Comparative Study by Behnam Nadali, Arman Abdous, Nima Karami, Mohammad Jokar, Ourang Ataie Amarloie, Mehran Farhoodi

“…ABSTRACT Human chorionic gonadotropin (hCG) is widely used to treat reproductive dysfunction by enhancing testicular blood flow and stimulating hormonal activity. …”
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Renal outcome of children with unilateral renal agenesis by Çağla Serpil Doğan, Meral Torun Bayram

“…In conclusion, urological anomalies usually accompany URA and should be followed closely to decrease the risk of renal failure. …”
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Correlation between Age and Surgical Approach for Thoracic and Lumbar Hemivertebra by Alexandrina Nikova, Varvara Chatzipaulou, Belkis Malkots, Reichan Molla Mustafa, Christina Valsamidou, Theodosis Birbilis

“…Conclusion If not treated, HV leads to deterioration and dysfunction. The most optimal result, however, is achieved only when the surgical approach is applied according to age and rest of the accompanying factors, which should be considered in future management planning.…”
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Small-Fiber Neuropathy: An Etiology-Oriented Review by Alessandro Furia, Rocco Liguori, Vincenzo Donadio

“…Conclusions: Idiopathic forms of SFN remain the most prevalent in the literature, but association with different disorders (e.g., infectious, autoimmune) should prompt investigation for SFN in the presence of a congruent clinical picture (e.g., pain with neuropathic features).…”
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Association of co-existing vitamin B6 and B12 deficiency with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome: a case report by Stephan Hu, Sharon Brown-Kunin, Paul Martin, Yujie Wang

“…Conclusions Patients with POEMS syndrome may have symptoms that are difficult to distinguish from deficiencies in vitamin B6 or vitamin B12. Management of POEMS should include screening of vitamin B6 and B12 to ensure other possible associated causes of symptoms are appropriately treated.…”
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Effect of Vestibular Stimulation on Balance and Gait in Parkinson’s Disease: A Systematic Review by Ardavan Iravani-Naeeni, Amir Mohagheghi

“…<b>Conclusions:</b> While VS appears to offer potential benefits in improving balance and gait in PwP, the presence of biases in the reviewed studies necessitate caution in interpreting the results. Further research should focus on addressing these biases to confirm the therapeutic potential of VS in PD.…”
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Harnessing mitochondrial biogenesis to combat acute kidney injury: Current insights and futuredirections by Yajie Hao, Fahui Chen, Xiya Ren, Xiu Huang, Xiaoshuang Zhou

“…AKI suppresses MB, resulting in mitochondrial dysfunction, oxidative stress, and further renal damage. …”
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Angiostrongylosis meningomyelitis without blood eosinophilia by Thanyalak Amornpojnimman, Nuttha Sanghan, Nichanan Ekpitakdamrong, Prut Koonalinthip, Sumonthip Leelawai, Pornchai Sathirapanya

“…A 44-year-old man developed acute paraplegia with bowel and bladder dysfunction. Spinal magnetic resonance images showed a long T2W hyperintensity signal from the 1st to 8th spinal thoracic level. …”
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Fever as a Catalyst for Life‐Threatening Arrhythmias in Brugada Syndrome: A Rare Case of Brugada Syndrome Unmasked in a Young Male by Ibrahim Khalil, Md. Imran Hossain

“…Febrile states exacerbate sodium channel dysfunction, increasing the likelihood of ventricular arrhythmias and SCD. …”
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Oxygenator Is the Main Responsible for Leukocyte Activation in Experimental Model of Extracorporeal Circulation: A Cautionary Tale by Alessio Rungatscher, Maddalena Tessari, Chiara Stranieri, Erika Solani, Daniele Linardi, Elisabetta Milani, Alessio Montresor, Flavia Merigo, Beatrice Salvetti, Tiziano Menon, Giuseppe Faggian

“…The present study has generated fundamental information on the role of oxygenator of ECC in activating inflammatory signaling pathways on leukocytes, leading to systemic inflammatory response, and organ dysfunction. The present results suggest that experimental animal models of ECC used in translational research on inflammatory response should be based on standardized, reproducible oxygenators with clinical characteristics.…”
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