Omega-3 fatty acids: multi-target mechanisms and therapeutic applications in neurodevelopmental disorders and epilepsy by Miao Li, Zhiqiang Li, Yuying Fan

“…This review summarizes the multi-pathway roles of Omega-3 fatty acids in NDDs and epilepsy, emphasizing the potential as a core component of integrated treatment strategies. Future studies should prioritize precision nutrition approaches and functional food development to optimize patient outcomes in neuropsychiatric care.…”
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Hypogonadism in the Aging Male Diagnosis, Potential Benefits, and Risks of Testosterone Replacement Therapy by Prasanth N. Surampudi, Christina Wang, Ronald Swerdloff

“…These symptoms include decreased libido, erectile dysfunction, decreased vitality, decreased muscle mass, increased adiposity, depressed mood, osteopenia, and osteoporosis. …”
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Overlapping Clinical Manifestations of Multisystem Inflammatory Syndrome in Children with Other Endemic Diseases of Pakistan: A Case Report by Anam Zafar, Sughra Wahid, Asad Ullah, Hassan Mumtaz

“…MIS-C should be kept in the differentials of diseases with multisystem involvement in the wake of the COVID-19 pandemic, as its clinical spectrum closely mimics other endemic illnesses of tropical and subtropical regions.…”
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Advances in brain and religion studies: a review and synthesis of recent representative studies by Patrick McNamara, Patrick McNamara, Patrick McNamara, Jordan Grafman, Jordan Grafman

“…To adequately account for SA perceptions, however, recent evidence suggests that REM sleep and dreaming mechanisms likely play a role. Future research should examine neurodevelopmental mechanisms of acquired SA perceptions as well as societal-level effects such as brain mediated religious beliefs of in-group cohesion and out-group hostility.…”
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How to choose appropriate medication for overactive bladder: Findings from the largest integrated clinical trial database analysis of mirabegron studies by Hann-Chorng Kuo

“…However, if the patients have risk of cognitive dysfunction, a history of constipation, dry mouth, and urinary retention, starting with mirabegron 50 mg might be more safe and appropriate. …”
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Post-stroke emotional incontinence or bipolar disorder? by Mnif L, Sellami R, Masmoudi J

“…Conclusion: The clinician should carefully explore any history of premorbid bipolar disorder, personality disorder characterized by mood instability, and family history of bipolar disorder. …”
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A rare case report of catecholamine-induced takotsubo in a patient with anaphylaxis shock due to amoxicillin–clavulanate by Thang Quoc Le, Thanh Huu Nguyen, Anh Duc Vu, Hai Dang Pham

“…Regardless of the duration of the event or the optimal epinephrine dosage in patients with anaphylactic shock, physicians should be aware of the risk of TTS.…”
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Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish. by Anna L Chapman, Ellen J Bennett, Tennore M Ramesh, Kurt J De Vos, Andrew J Grierson

“…Our findings support the idea that MFN2 mutation status should be investigated in patients presenting with early-onset recessively inherited axonal CMT.…”
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Challenges in the implementation of cardio-oncology trials: lessons learnt from investigating statins in the prevention of anthracycline cardiotoxicity by John Lee, Sean Tan, Satish Ramkumar

“…Addressing these challenges collaboratively between oncology and cardiology will be crucial for optimizing patient outcomes in this vulnerable population. Future studies should emphasize both immediate cardioprotective effects and long-term cardiovascular benefits of statins, especially in the context of atherosclerotic cardiovascular disease in cancer survivors.…”
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Sex and Age Differences in the Impact of Metabolic Syndrome on Heart Failure Development by Tae-Eun Kim, Do Young Kim, Hyeongsu Kim, Sung Hea Kim

“…The pathophysiological mechanisms linking MetS to HF are complex and multifaceted, with the components of MetS contributing to cardiac deterioration through impaired myocardial energy metabolism, increased inflammation, and endothelial dysfunction. Numerous clinical studies have confirmed the relationship between MetS and HF. …”
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Hypokalemic Paralysis Secondary to Immune Checkpoint Inhibitor Therapy by Pragathi Balakrishna, Augusto Villegas

“…Hence, given the increasing frequency of immunotherapy use, awareness should be raised in regard to irAEs and their appropriate management.…”
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Rivastigmine as a Symptomatic Treatment for Apathy in Parkinson’s Dementia Complex: New Aspects for This Riddle by Rita Moretti, Paola Caruso, Matteo Dal Ben

“…Similar to other NPS, apathy may be due to a dysfunction of the nigrostriatal pathway, even though, not all the PD patients become apathetic, indicating that apathy should not entirely be considered a dopamine-dependent syndrome, and in fact it might also be related to acetylcholine defects. …”
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Rheumatoid arthritis and bacterial infections by N L Prokopjeva, N N Vesikova, I M Marusenko, V A Ryabkov

“…So timely detection and proper sanation of infection focuses should be performed in pts with RA…”
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Modulation of Oxidative Stress in Diabetic Retinopathy: Therapeutic Role of Natural Polyphenols by Verónica Gómez-Jiménez, Raquel Burggraaf-Sánchez de las Matas, Ángel Luis Ortega

“…Nanotechnology-based delivery systems enhance drug stability, tissue targeting, and sustained release, offering potential for early intervention. Future strategies should integrate antioxidant therapies and precision diagnostics to prevent early irreversible retinal damage in diabetic patients.…”
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Immunomodulatory Activity of Granulocyte Colony-Stimulating Factor and its Therapeutic Effect on Liver Failure by Jinhua Hu, Zijian Sun, Jingjing Tong, Jing Chen, Zifeng Liu, Haijuan Wang

“…Liver failure is characterized by the rapid deterioration of liver function, often accompanied by ascites, coagulation dysfunction, hepatic encephalopathy, and other critical complications. …”
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Cardiovascular Effectiveness and Safety of Antidiabetic Drugs in Patients with Type 2 Diabetes and Peripheral Artery Disease: Systematic Review by Antonio Cimellaro, Michela Cavallo, Marialaura Mungo, Edoardo Suraci, Francesco Spagnolo, Desirée Addesi, Medea Pintaudi, Carmelo Pintaudi

“…Therefore, the clinical approach should not ignore vascular protection with the aim of reducing limb and overall CV events besides a mere glucose-lowering effect. …”
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Impact of adjuvant trastuzumab therapy and its discontinuation on cardiac function and mortality in patients with early-stage breast cancer: An analysis based on the Japanese Recei... by Keiko Miyazato, Hiroshi Ohtsu, Akihiko Shimomura, Naohiro Yonemoto, Chikako Shimizu, Kazuhiro Sase, Shinichiro Ueda

“…However, trastuzumab-induced cardiac dysfunction may force the discontinuation of adjuvant trastuzumab therapy. …”
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Hashimoto’s thyroiditis and nanophthalmos in Gabriele-de Vries syndrome: a case report by Hui Huang, Dongguang Zhang, Yu Yang, Li Yang, Yong Chai

“…This suggests that thyroid dysfunction in GADEVS may be associated with underlying immune dysfunction and warrants further evaluation. …”
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Outcomes of pediatric heart transplantation in children with selected genetic syndromesCentral MessagePerspective by Sarah Wilkens, MD, MPH, Jaimin Trivedi, MBBS, MPH, Deborah Kozik, MD, Andrea Nicole Lambert, MD, MSCI, Bahaaldin Alsoufi, MD

“…Although early and late post-transplantation care is individualized to each patient, the presence of a GS should not influence the decision to list for HT.…”
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Predictors, prevalence and prognostic role of pulmonary hypertension in patients with chronic kidney disease: a systematic review and meta-analysis by Chunlong Lin, Qilong Ge, Lei Wang, Pan Zeng, Mingmin Huang, Dan Li

“…Therefore, patients with high prevalence of PH should be identified for treatment.…”
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