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Optimization on construction machinery considering sequence-dependent setup times and personnel fatigue based on the improved gray wolf and whale algorithm.
Published 2025-01-01“…Through rigorous analysis and comparison with existing algorithms, the proposed IHWGWO demonstrates a significant reduction in both iteration count and financial expenditure. …”
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Study on the Division of the Affected Zone under Construction Unloading and Its Construction Sequence of the Multiline Parallel River-Crossing Pipe Jacking
Published 2023-01-01“…For further discussion, the construction sequence of the multiline parallel river-crossing pipe jacking has been studied.…”
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Transcriptomic sequencing and expression verification of identified genes modulating the alkali stress tolerance and endogenous photosynthetic activities of industrial hemp plant.
Published 2025-01-01“…Transcriptomic analysis (RNA-sequencing) revealed the considerably enriched GO terms as well as KEGG pathways that exposed the significant DEGs. …”
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Impact of the Spatiotemporal Relationship Between Blast Source and Protected Area on Wave Arrival Sequence and Vibration Control Methods in Bench Blasting
Published 2025-04-01“…Following the Anderson principle, reconstructed single-hole vibrations are superimposed according to the wave arrival sequence to validate control efficacy. Statistical analysis of concurrent wave arrivals across all-direction monitoring points identifies high-probability vibration hazard locations. …”
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Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women
Published 2025-08-01“…Genetic testing facilitates screening and informs targeted risk-reduction and treatments. However, genes included in testing panels are from European-ancestry studies. …”
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Unraveling the significance of cuproptosis in hepatocellular carcinoma heterogeneity and tumor microenvironment through integrated single-cell sequencing and machine learning appro...
Published 2025-05-01“…Methods Single-cell RNA sequencing data were obtained from the GEO database and processed using the Seurat R package for quality control, including data filtering, batch effect correction, and dimensionality reduction via PCA and UMAP to visualize cell distribution and identify distinct subpopulations. …”
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Comparison of CT-like MRI sequences for preoperative planning of cochlear implantation using super-high-resolution CT as a reference
Published 2025-01-01“…Methods Six cadaveric temporal bone specimens were used. 3-T MRI scans were performed using radial volumetric interpolated breath-hold (STARVIBE), pointwise-encoding time reduction with radial acquisition (PETRA), and ultrashort time of echo (UTE) sequences. …”
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High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy
Published 2025-08-01“…This study employs high-throughput sequencing-based transcriptomics to investigate AMA-associated dysregulation in placental angiogenesis, exploring links to redox imbalance. …”
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Single nuclei RNA-sequencing unveils alveolar macrophages as drivers of endothelial damage in obese HFpEF-related pulmonary hypertension
Published 2025-07-01“…Single nucleus RNA-sequencing (snRNA-seq) was employed to study the AMs transcriptional landscape and cell-cell interactions. …”
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KDDC: a new framework that integrates kmers, dataset filtering, dimension reduction and classification algorithms to achieve immune cell heterogeneity classification
Published 2025-05-01“…IntroductionIntegrating immune repertoire sequencing data with single cell sequencing data offers profound insights into the diversity of immune cells and their dynamic changes across various disease states.MethodsHere, we propose a novel KDDC framework that integrates kmers, dataset selection, dimensionality reduction and classification algorithms to facilitate the heterogeneous classification of immune cells.Results and DiscussionBy comparing various kmer length combinations across seven different classification algorithms, we found that B cell receptor-based cellsubset classification outperforms T cell receptor-based classification, achievingan average AUC of over 96%. …”
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Reduction in mitochondrial DNA methylation leads to compensatory increase in mitochondrial DNA content: novel blood-borne biomarkers for monitoring occupational noise
Published 2025-05-01“…MtDNA damage was evaluated through mitochondrial DNA copy number (mtDNAcn) and lesion rate, and mtDNA methylation changes were identified via pyrophosphate sequencing. Results: There was a reduction in MT-RNR1 methylation of 4.52% (95% CI: −7.43% to −1.62%) among workers with abnormal hearing, whereas changes in the D-loop region were not statistically significant (β = −2.06%, 95% CI: −4.44% to 0.31%). …”
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The clinical management and efficacy of metagenomic next-generation sequencing in patients with pyogenic spinal infection: a single-center cohort study
Published 2024-11-01“…Abstract Objective This study aims to evaluate the clinical management and effectiveness of metagenomic next-generation sequencing (mNGS) in patients with pyogenic spinal infections. …”
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Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with brucellosis resistance/susceptibility in Shami goat
Published 2025-01-01“…On the other hand, there were significant reductions in the glucose, total protein albumin, urea, calcium, inorganic phosphorus, sodium, copper, zinc, iron, TAC, GSH, SOD, GPx, IL-10 and fibrinogen in the infected compared to the non-infected does. …”
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A phraseological and phonological analysis of don’t: A stay abroad perspective
Published 2021-12-01Get full text
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Identification of yield-related QTLs and their applications using DH population in maize
Published 2025-08-01“…Concurrently, we observed a reduction in ear height (EH), which is also a favorable phenotype in maize. …”
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