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1901
Investigating the effects of various irrigation methods on bacterial communities in paddy soil
Published 2024-12-01“…The study evaluated the impact mechanisms of different irrigation methods on these bacterial communities. …”
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1902
Molecular mechanisms of cryoablation-mediated lung cancer suppression unveiled by non-coding RNA regulatory network profiling
Published 2025-08-01“…RNA sequencing identified differentially expressed genes (DEGs), and bioinformatics analysis constructed lncRNA/miRNA-mRNA regulatory networks, with key targets validated by RT-qPCR and Western blotting. …”
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1903
The influence of the geroprotective cytokine on the transcriptome of young and senescent mesenchymal stem cells
Published 2025-04-01“…Data description To evaluate transcriptomic changes induced by the potential geroprotective factor GDF11, we performed RNA sequencing on four groups of samples: ‘young’ MSCs (MmC-/GDF11-) and senescent MSCs (MmC+/GDF11-) without the addition of GDF11, as well as ‘young’ (MmC-/GDF11+) and senescent MSCs (MmC+/GDF11+) with the addition of GDF11. …”
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1904
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1905
Integrated multi-omics and machine learning reveal an immunogenic cell death-related signature for prognostic stratification and therapeutic optimization in colorectal cancer
Published 2025-07-01“…Through the integrative analysis of single-cell RNA sequencing and bulk transcriptomic data, 11 ICD-related genes with prognostic significance were identified in CRC. …”
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1906
Identification of a deubiquitinating gene-related signature in ovarian cancer using integrated transcriptomic analysis and machine learning framework
Published 2025-04-01“…Methods We conducted an integrated analysis of single-cell RNA sequencing and bulk transcriptome data from public databases. …”
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1907
Single cell transcriptomics in blood of patients with chronic obstructive pulmonary disease
Published 2025-01-01“…Hence, we evaluated gene expression in the peripheral blood of patients with COPD. …”
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1908
Indoor potted plants have little effect on office dust fungal communities
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1909
Pets in the household increase ocular surface microbiome exchanges between dog and owner
Published 2025-06-01“…This study investigates sharing of ocular surface microbiome between dogs and owners by characterizing dog and owner ocular microbiomes, and evaluating the impact of several lifestyle factors on microbiome similarities between them.To this aim, conjunctival swabs were collected from 15 dogs and their owners for subsequent DNA extraction and 16S rRNA V3-V4 regions sequencing. …”
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1910
3D printed magnesium silicate/β-tricalcium phosphate scaffolds promote coupled osteogenesis and angiogenesis
Published 2025-01-01“…In this research, we evaluated and analyzed magnesium silicate/β-Tricalcium phosphate (MS/β-TCP) scaffold on angiogenesis and bone regeneration in vitro and in vivo, and the mechanism of its action were described. …”
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1911
Synergistic antifungal activity of minocycline as an effective augmenting agent of fluconazole against drug-resistant Candida tropicalis
Published 2025-05-01“…Whole-genome and RNA sequencing elucidated the synergistic mechanisms observed. …”
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1912
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1913
Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease
Published 2025-02-01“…The Mini-Mental State Examination (MMSE) was utilized to evaluate cognitive function. High-throughput sequencing was used to identify differentially expressed miRNAs in plasma exosomes, while metagenomic sequencing was employed to detect differences in the abundance of gut microbiota. …”
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1914
High-throughput based detection of eukaryotic pathogens for sea cucumber in Dalian costal area
Published 2025-04-01“…Concurrently, various environmental factors were measured seasonally to evaluate their potential impacts on the relative abundance of the identified pathogens. …”
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1915
Identification of QTLs and candidate genes screening for hypoxia tolerance in Pacific white shrimp (Litopenaeus vannamei)
Published 2025-07-01“…This study aimed to uncover the genetic basis of hypoxia tolerance to enhance farming efficiency and sustainability. We evaluated hypoxia tolerance in a shrimp mapping family and identified quantitative trait loci (QTLs) and candidate genes associated with this trait. …”
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1916
Identification of circRNA expression signatures correlated with disease severity in pediatric systemic lupus erythematosus
Published 2025-07-01“…The potential of circRNAs as biomarkers for SLE severity was evaluated through receiver operating characteristic (ROC) analysis. …”
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1917
Clinical Application of a Customized Gene Panel for Identifying Autism Spectrum Disorder-Associated Variants
Published 2025-07-01“…Despite the recent advantages in next-generation sequencing (NGS) technology, ASD etiology is still unclear. …”
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1918
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1919
Copper Metabolism-Related Genes as Biomarkers in Colon Adenoma and Cancer
Published 2025-06-01“…The degree of immune infiltration was evaluated using single-sample Gene Set Enrichment Analysis (ssGSEA), and the expression profiles of these biomarkers across various cell types were further characterized using single-cell RNA sequencing (scRNA-seq). …”
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1920