Gamma-ray spectrometric evaluation in watersheds with gold anomalies in stream sediments, Passo Feio Complex, Caçapava do Sul region (Brazil) by Luiza Lima Alves, César Augusto Moreira, Ana Flávia da Silva Araújo, Lenon Melo Ilha, João Pedro Prado de Oliveira, Sissa Kumaira, Marco Antonio Fontoura Hansen, Henri Masquelin

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Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs by Kelley Kilpatrick, Jonah N. Cullen, Farah F. Almeer, LeeAnn Higgins, Todd Markowski, Marjory Brooks, Steven G. Friedenberg, Molly Racette

“…ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. …”
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Lung-directed delivery of a ligand-mediated chimeric lysin has an enhanced ability to eradicate pulmonary and intracellular Staphylococcus aureus by Xiaoxu Zhang, Dongyan Xiong, Xiaohong Li, Heng Xue, Min Chen, Junping Yu, Hongping Wei

“…Antimicrobial activities of the two lysins (ClyC, p-ClyC) against S. aureus were evaluated in vitro and in a murine lung infection model. …”
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Discovering the Potential Role of the C2 DUSP2+ MCs Subgroup in Lung Adenocarcinoma by Shengyi Zhang, Xinhan Li, Zhikai Xiahou, Ailing Chen, Renfang Sun, Chao Liu, Jie Yuan

“…CCK-8 assay could validate the activity of a specific cell subgroup sequenced in single cell sequencing to confirm the role of this cell subgroup in tumor proliferation. …”
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Host-mimicking conditions promote Pseudomonas aeruginosa PA14 virulence gene expression by Amber Grace, Rajnish Sahu, Donald R. Owen, Vida A. Dennis

“…RNA sequencing showed that multiple Type III Secretion (T3SS), Type I Secretion (T1SS), pyoverdine biosynthesis, uptake and efflux, and Type IV pili (T4P) initiation genes were promoted when PA14 was transitioned into host-mimicking conditions but remained unchanged when transitioned into standard AST conditions. …”
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Radiation target: Moving from theory to practice by Qian Li, Guoping Zhao, Wei Han, Shengmin Xu, Lijun Wu

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New insight into the development of synpolydactyly caused by expansion of HOXD13 polyalanine based on weighted gene co-expression network analysis by Xiumin Chen, Xiaofang Shen, Tao Yang, Yixuan Cao, Xiuli Zhao

“…Conclusions These findings evaluated the main genes related to SPD with PAE mutations in HOXD13 and advance our understanding of human limb development.…”
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Results of various somatic mutations detection in patients with chronic myeloid leukemia by E. A. Kuzmina, E. Yu. Chelysheva, B. V. Biderman, O. A. Shukhov, E. A. Stepanova, E. P. Gadzhieva, A. N. Petrova, I. S. Nemchenko, A. V. Bykova, M. A. Guryanova, A. V. Kokhno, A. G. Turkina, A. B. Sudarikov

“…Somatic mutations in chronic myeloid leukemia (CML) patients are considered as possible factors for the failure of tyrosine kinase inhibitor (TKI) therapy, and the study of their characteristics is of interest.Aim. To evaluate the genetic profile of blood cells in CML patients using nextgeneration sequencing.Materials and methods. …”
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Data simulation to optimize frameworks for genome-wide association studies in diverse populations by Jacquiline W. Mugo, Nicola Mulder, Emile R. Chimusa

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Analysis of the effect of caffeine on the efficiency of wastewater treatment processes by integrated methods by Angelika Skorupa, Małgorzata Worwąg, Mariusz Kowalczyk

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Exploring Cancer Patients’ and Caregivers’ Perspectives and Knowledge Regarding Biomarker Testing in Canada by Patil Mksyartinian, Selina Xu, Chrissa Barroma, Sandra Peláez, Barry D. Stein

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Oxcarbazepine may be an effective option for Chinese pediatric patients with self-limited focal epilepsy of neonatal/infantile onset: a retrospective cohort study by Na Sun, Xueying Wang, Shaoping Huang, Lin Yang, Dan Li

“…All children were followed up regularly in the outpatient clinic.ResultsThe 26 children, 13 male and 13 female, were followed for a mean of 54.0 (49.0, 58.5) months. Trio whole-exome sequencing (WES) revealed no pathogenic genetic abnormalities in 16 children, and known pathological genes including PRRT2, SCN2A and KCNQ2 were detected in 10 children. …”
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Genomic Insights into <em>Stutzerimonas kunmingensis</em> TFRC-KFRI-1 Isolated from Manila Clam (<em>Ruditapes philippinarum</em>): Functional and Phylogenetic Analysis by Myunglip Lee, Sunghun Yi, Jiho Choi, Yukyoung Park, Chaehyeon Lim, Yucheol Kim

“…This strain, belonging to the family <i>Pseudomonadaceae</i>, was previously classified as <i>Pseudomonas kunmingensis</i> but later reclassified to the genus <i>Stutzerimonas</i>, known for species with bioremediation and probiotic properties. To evaluate its genomic features and potential applications, we performed draft-genome sequencing and analysis. …”
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Genomic analysis for the identification of bioactive compounds in Xenorhabdus stockiae strain RT25.5 by Wipanee Meesil, Helge B. Bode, Christian Rückert-Reed, Yi-Ming Shi, Sacha J. Pidot, Paramaporn Muangpat, Triwit Rattanarojpong, Narisara Chantratita, Sutthirat Sitthisak, Apichat Vitta, Aunchalee Thanwisai

“…Through high-throughput genome sequencing, assembly, and annotation, followed by advanced bioinformatics analyses, we elucidated the genetic basis of its antimicrobial potential. …”
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Spectrum of VHL mutations in clear cell renal cell carcinoma by N. N. Mazurenko, I. V. Tsyganova, V. V. Strelnikov, A. V. Balbutsky, T. F. Malivanova, E. B. Kuznetsova, V. A. Draudin-Krilenko, O. V. Shangina, A. F. Mukeria, V. B. Matveev, D. G. Zaridze

“…The DNA samples were obtained from snap-frozen carcinoma biopsies and used for Sanger sequencing, while 62 ccRCC DNA cases were studied by next generation sequencing (NGS) analysis in parallel. …”
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Novel loss-of-function mutations in VPS13A cause chorea-acanthocytosis in two families by Xiao-Hong Lin, Bin Xiao, Ru-Kai Chen, Jia-Ying Chen, Nai-Qing Cai, Chun-Yan Cao, Li-Qiong Zhan

“…This article reports two families with ChAc and summarizes some suggestive characteristics, providing an effective basis for clinicians to screen ChAc in the early stage and effectively reduce the misdiagnosis and missed diagnosis of this disease.MethodsWe first performed whole-exome sequencing (WES) and confirmed three NA cases in two families. …”
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Effect of Bio-Fermented Distillers Grain on Growth, Intestines, and Caecal Microbial Community in Broilers by Ping Xu, Changsong Liu, Hongxia Ding, Pinpin Chen, Xin Fan, Xu Wang, Shijie Li, Jintao Peng, Zutao Zhou, Deshi Shi, Shengbo Cao, Yuncai Xiao

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Population Structure and Genetic Diversity of Agave Germplasms in China by Xiaoli Hu, Yubo Li, Shibei Tan, Lisha Chen, Dietram Samson Mkapa, Chen Lin, Qingqing Liu, Gang Jin, Tao Chen, Xu Qin, Kexian Yi, Xing Huang

“…Cost-effective amplicon sequencing technology was used to identify genetic variants. …”
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Development and Application of Novel SSR Markers to Assess the Genetic Diversity and Population Structure of <i>Phacelia secunda</i> Along an Altitudinal Gradient in the Central Ch... by Cristian Torres-Díaz, Ana Ortíz-Sepúlveda, Moisés A. Valladares, Darío Farias-Cantillana, Marco A. Molina-Montenegro, Gabriel I. Ballesteros

“…In this study, we developed and characterized novel polymorphic microsatellites for this species, using an Illimina MiSeq sequencing platform. Nineteen polymorphic loci were obtained, with alleles numbers ranging from 3 to 13 per locus (mean = 5.84). …”
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Influence of Different Transposon Families on Genomic Stability of Shewanella oneidensis MR1 by Benjamin Fritz, Christian Jonas Lapp, Johannes Gescher

“…This study focused on transposases, specifically insertion sequences (IS), which make up approximately 4.7% of the organism's genome, and evaluated their impact on genome stability under stress conditions. …”
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