Development of a highly sensitive luciferase assay for intracellular evaluation of coronavirus Mpro activity by Bao Dong, Bao Dong, Yuehong Chen, Xin Wang, Jing Li, Sen Zhang, Xiaoping Kang, Yuchang Li, Biao Li, Liangning Liao, Zhengwei Zhang, Jiaqi Xiong, Lele Shao, Shenghai Huang, Ye Feng, Tao Jiang, Tao Jiang, Tao Jiang, Tao Jiang

“…Additionally, the system proved suitable for evaluating and screening of antiviral compounds, including lufotrelvir, GC376, Nirmatrelvir, X77, MG-101, and the potential inhibitor Cynaroside. …”
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The value of multi-sequence magnetic resonance imaging and whole-tumor apparent diffusion coefficient histogram analysis in differentiating p53 abnormal from non-p53 abnormal endom... by Yuying Sun, Jieying Zhang, Yilin Wang, Xinxin Zhang, Yan Chen

“…MinADC demonstrated the highest discrimination ability in differentiating p53abn from non-p53abn EC [AUC 0.70(0.60;0.80)].ConclusionPreoperative multi-sequence MRI findings and whole-tumor ADC histogram metrics are conducive to differentiating p53abn from non-p53abn EC.…”
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Investigating fungal diversity through metabarcoding for environmental samples: assessment of ITS1 and ITS2 Illumina sequencing using multiple defined mock communities with differe... by Raf Winand, Elizabet D’hooge, Alexander Van Uffelen, Bert Bogaerts, Julien Van Braekel, Stefan Hoffman, Nancy H. C. J. Roosens, Pierre Becker, Sigrid C. J. De Keersmaecker, Kevin Vanneste

“…Classification performance was first evaluated using ITS1 and ITS2 sequences of all species in the DMCs, generated by Sanger sequencing, to evaluate the discriminatory power of ITS and set a baseline for subsequent comparison with Illumina sequencing. …”
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Genetic Diversity of Local Wheat (<i>Triticum aestivum</i> L.) and Traceability in the Production of Galician Bread (Protected Geographical Indication) by Microsatellites by Luís Urquijo-Zamora, Santiago Pereira-Lorenzo, Ángeles Romero-Rodríguez, Matilde Lombardero-Fernández, Ana María Ramos-Cabrer, Cristina Isabel Fernández-Otero

“…Seventeen simple sequence repeats (SSRs) were evaluated to elucidate their genetic structure, determine their origins, and differentiate them from commercial cultivars for traceability purposes. …”
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A hybrid algorithm for flexible job-shop scheduling problem with setup times by Ameni Azzouz, Meriem Ennigrou, Lamjed Ben Said

“…The FJSP problems cover two difficulties, namely, machine assignment problem and operation sequencing problem. This paper addresses the flexible job-shop scheduling problem with sequence-dependent setup times to minimize two kinds of objectives function: makespan and bi-criteria objective function. …”
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Contestable AI for criminal intelligence analysis: improving decision-making through semantic modeling and human oversight by Falk Maoro, Michaela Geierhos

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MMPred: a tool to predict peptide mimicry events in MHC class II recognition by Filippo Guerri, Filippo Guerri, Valentin Junet, Valentin Junet, Judith Farrés, Xavier Daura, Xavier Daura, Xavier Daura

“…We present MMPred, a software tool that integrates epitope prediction and sequence alignment algorithms to streamline the computational analysis of molecular mimicry events in autoimmune diseases. …”
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Prediction-Based Tip-Over Prevention for Planetary Exploration Rovers by Siddhant Shete, Raúl Domínguez, Ravisankar Selvaraju, Mariela De Lucas Álvarez, Frank Kirchner

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Assessment of the association of ACE gene polymorphism with acute coronary syndrome in patients after a coronavirus disease 2019 by L. A. Shpagina, V. A. Kozik, V. N. Maksimov, I. S. Shpagin, L. A. Panacheva, S. A. Karmanovskaya, N. G. Lozhkina

“…Aim. To evaluate the association of the nucleotide sequence variant rs1799752 (I/D) of the angiotensin-converting enzyme (ACE) gene with acute coronary syndrome (ACS) in patients after a coronavirus disease 2019 (COVID-19).Material and methods. …”
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Impact of Chemotherapy Alone and in Combination with Immunotherapy on Oral Microbiota in Cancer Patients—A Pilot Study by Adriana Padure, Ioana Cristina Talpos-Niculescu, Paula Diana Ciordas, Mirabela Romanescu, Aimee Rodica Chis, Laura-Cristina Rusu, Ioan Ovidiu Sirbu

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A causal intervention framework for synthesizing mobility data and evaluating predictive neural networks by Ye Hong, Yanan Xin, Simon Dirmeier, Fernando Perez-Cruz, Martin Raubal

“…We evaluate the interventional location sequences using mobility metrics and input them into well-trained networks to analyze performance variations. …”
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Combining and congruence evaluation of phylogenetic signals from different genes based on geometric approach by V. M. Efimov, V. Yu. Kovaleva, Yu. N. Litvinov

“…All sequences of each gene are represented as a set of points in Euclidean space. …”
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Human TCR repertoire in cancer by Lin Chen, Yuan Hu, Bohao Zheng, Limei Luo, Zhenzhen Su

“…The TCR repertoire analysis, enabled by advanced sequencing technologies, is poised to become a crucial tool in the future of cancer diagnosis, monitoring, and therapy evaluation.…”
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Detection and Evaluation of Non-Recombinants in cDNA Libraries by Multiple Cloning Region PCR by Dilip Bandyopadhyay, Farhad D. Vesuna

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Multi-Parametric MRI Combined with Radiomics for the Evaluation of Lymphovascular Space Invasion in Cervical Cancer by Huanhuan Wang, Jie Meng, Guoqiang Dong, Lijing Zhu, Zhengyang Zhou, Yuan Jiang, Li Zhu

“…Background: To explore the feasibility of radiomic models using different magnetic resonance imaging (MRI) sequences combined with clinical information in evaluating the status of lymphovascular space invasion (LVSI) in cervical cancer. …”
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Rapid, user-friendly, cost-effective DNA and library Preparation methods for whole-genome sequencing of bacteria with varying cell wall composition and GC content using minimal DNA... by Bertrand Bearzatto, Jean-François Durant, Jérôme Ambroise, Jean-Luc Gala

“…Results Whole-genome sequencing performance was evaluated on Bacillus cereus (B. cereus), Staphylococcus epidermidis (S. epidermidis), and Enterobacter cloacae (E. cloacae) ATCC strains. …”
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Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circula... by Le Son Tran, Hong-Anh Thi Pham, Vu-Uyen Tran, Thanh-Truong Tran, Anh-Thu Huynh Dang, Dinh-Thong Le, Son-Lam Nguyen, Ngoc-Vu Nguyen, Trieu-Vu Nguyen, Binh Thanh Vo, Hong-Thuy Thi Dao, Nguyen Huu Nguyen, Tam Huu Tran, Chu Van Nguyen, Phuong Cam Pham, Anh Tuan Dang-Mai, Thien Kim Dinh-Nguyen, Van Hieu Phan, Thanh-Thuy Thi Do, Kiet Truong Dinh, Han Ngoc Do, Minh-Duy Phan, Hoa Giang, Hoai-Nghia Nguyen

“…In this study, we developed a protocol for liquid biopsy using ultra-deep massively parallel sequencing (MPS) with unique molecular identifier tagging and evaluated its performance for the identification and quantification of tumor-derived mutations from plasma of patients with advanced NSCLC. …”
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Evaluation of a Rhenium(I) Complex and Its Pyridostatin-Containing Chelator as Radiosensitizers for Chemoradiotherapy by António Paulo, Sofia Cardoso, Edgar Mendes, Elisa Palma, Paula Raposinho, Ana Belchior

“…G-quadruplex (G4) DNA ligands have emerged in recent years as a potential new class of radiosensitizers binding to specific DNA sequences. Recently, we have shown that the Re(I) tricarbonyl complex PDF-Pz-Re and its pyrazolyl-diamine chelator PDF-Pz, carrying a <i>N</i>-methylated pyridostatin (PDF) derivative, act as G4 binders of various G4-forming DNA and RNA sequences. …”
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Evaluation of 16S rRNA Databases for Taxonomic Assignments Using a Mock Community by Sang-Cheol Park, Sungho Won

“…Particularly in metagenomics, which identifies the composition of microorganisms using thousands of sequences, its importance is even greater. Identification is inevitably affected by the choice of database. …”
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Full-time sequence assessment of okra seedling vigor under salt stress based on leaf area and leaf growth rate estimation using the YOLOv11-HSECal instance segmentation model by Xiaowei Cao, Yifan Li, Yaben Zhang, Zhibo Zhong, Ruxiao Bai, Peng Yang, Feng Pan, Xiuqing Fu

“…A high-throughput, Full-Time Sequence Crop Germination Vigor Monitoring System was developed to automatically capture image data from seed germination to seedling growth stage, while maintaining stable temperature and lighting conditions. …”
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