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Integrated Analysis of Single‐Cell and Bulk RNA‐Sequencing Defines N7‐Methylguanosine (m7G)‐Mediated Modifications' Role in Prognosis and the Tumor Immune Microenvironment in Hepat...
Published 2025-06-01“…Method Single‐cell RNA sequencing (scRNA‐seq) data was sourced from the GEO repository. …”
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Whole-exome sequencing identified a novel heterozygous variant in UBAP2L in a Chinese family with neurodevelopmental disorder characterized by impaired language, behavioral abnorma...
Published 2024-12-01“…The variant was inherited from the affected mother, and confirmed in the proband and his parents by Sanger sequencing. This is the first familial report of a deleterious UBAP2L variant. …”
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TET2 gene mutation status associated with poor prognosis of transition zone prostate cancer: a retrospective cohort study based on whole exome sequencing and machine learning model...
Published 2025-04-01“…Kaplan-Meier curves with log-rank testing and Cox regression models were applied to evaluate the prognostic significance of selected mutant driver gene and clinicopathological characteristics in a cohort of 132 patients with TZ PCa. …”
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Next-Generation Sequencing–Based Testing Among Patients With Advanced or Metastatic Nonsquamous Non–Small Cell Lung Cancer in the United States: Predictive Modeling Using Machine L...
Published 2025-06-01“… BackgroundNext-generation sequencing (NGS) has become a cornerstone of treatment for lung cancer and is recommended in current treatment guidelines for patients with advanced or metastatic disease. …”
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The Mechanism of Relieving Diarrheal Irritable Bowel Syndrome Using Polyphenols from <i>Ribes nigrum</i> L. Based on a Network Pharmacology Analysis and 16S rRNA Sequencing
Published 2024-11-01“…Finally, 16S rRNA sequencing and reverse q-RTPCR were utilized to evaluate the components that mediate the impact of RNPs on IBS-D. …”
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Biodegradation of ZEN by Bacillus mojavensis L-4: analysis of degradation conditions, products, degrading enzymes, and whole-genome sequencing, and its application in semi-solid-st...
Published 2025-03-01“…In this study, the strains with high degradation rate were screened through co-culture with ZEN, and identified by bacterial morphology, 16S rDNA sequencing and whole genome sequencing. The detoxification effect of L-4 strain on ZEN was evaluated under different ZEN concentration, treatment time, pH value and temperature, the degradation products were identified, and the degradation effect of L-4 strain on ZEN contaminated corn meal was evaluated. …”
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Effects of species and sex on the gut microbiome of four laboratory-reared fruit fly lines (Diptera: Tephritidae) using full-length 16S rRNA PacBio Kinnex sequencing
Published 2025-07-01“…We evaluated the gut microbiome of four lines of pest tephritid fruit fly adults (Bactrocera dorsalis, Bactrocera latifrons, Ceratitis capitata, Zeugodacus cucurbitae) using near full-length 16S rRNA sequencing with a PacBio Kinnex concatenation-based approach. …”
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Effect of individual variations in genes related to dopamine brain transmission on performance with and without rewards during motor sequence and probabilistic learning tasks in ch...
Published 2025-01-01“…Dopamine is a neurotrasmitter known to affect motor skill acquistion in animals and humans and may be influenced by individual variations in genes related to brain transmission of dopamine. To evaluate potential genetic influences on learning in young people with and without CP, we calculated individual dopamine-related gene scores and compared these to the ability to learn two different tasks, an implicit sequence learning task and a probablistic classification task. …”
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Genomic selection and weighted single-step genome-wide association study of sheep body weight and milk yield: Imputing low-coverage sequencing data with similar genetic background...
Published 2025-04-01“…ABSTRACT: Low-coverage whole-genome sequencing (LcWGS), a cost-effective genotyping method, offers greater flexibility in variant detection than SNP chips. …”
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Comparative analysis of bacterial abundance and diversity in tumour tissue of oral squamous cell carcinoma and non-tumour tissue: insights from a systematic review of 16S ribosomal...
Published 2025-04-01“…Result Evaluating the selected 13 articles, we have identified the exclusive and relative abundance of bacteriome in TT and NT at phylum, genus, and species levels. …”
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Temporally Unpredictable Sounds Exert a Context-Dependent Influence on Evaluation of Unrelated Images.
Published 2015-01-01“…It is unknown whether this influence is mediated by an evaluation of the unpredictable sound sequences themselves, or by an interaction with task context. …”
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Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality.
Published 2016-08-01“…Because the HIV-1 replication process is highly error-prone, the detection of identical viral genomes in distinct host cells provides evidence for the clonal expansion of infected cells. We evaluated alignments of unique, near-full-length HIV-1 sequences to determine the relationship between clonality in a short region and clonality in the full genome. …”
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Evaluation of DNA barcoding reference databases for marine species in the western and central Pacific Ocean
Published 2025-07-01“…While the quality of these databases has long been debated, a critical knowledge gap remains in their comprehensive evaluation and comparison at regional scales. Marine metazoan species in the western and central Pacific Ocean (WCPO), a region characterized by high biodiversity and limited sequencing efforts, are an example of this gap. …”
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Design and Evaluation of a Physical Protection System for a Radioactive Waste Intermediary Storage
Published 2022-12-01“…Therefore, it carried out an evaluation of the Physical Protection System (PPS) applying the DEPO (Design and Evaluation Process Outline) methodology with a sequence of three phases of the protection system design and assessment of its vulnerabilities. …”
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Safety of Simultaneous Scalp and Intracranial EEG and fMRI: Evaluation of RF-Induced Heating
Published 2025-05-01Get full text
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Long time-series and high-frequency ecological evaluation of Henan section of the Yellow River
Published 2025-01-01“…This study proposed a new Spatial-Temporal Comprehensive Evaluation of Eco-environment Quality Index (SCEQI) model. …”
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Evaluation of the Clinical Effects and Frequency of MEFV Gene Mutation in Patients with Inflammatory Bowel Disease
Published 2021-01-01“…Here, the frequency of Mediterranean Fever (MEFV) gene mutation and its effect on the outcome of IBD were evaluated. Methods. DNA sequence analysis detected the variants on the MEFV gene in patients with IBD. …”
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