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981
New Potential Ultracompact X-Ray Binaries for Space-based Gravitational-wave Detectors from a Low-mass Main-sequence Companion Channel
Published 2025-01-01“…We investigate the formation and evolution of ultracompact X-ray binaries (UCXBs) using the COMPAS binary evolution code, starting from the zero-age main sequence (MS). Focusing on the low-mass MS companion channel, we simulate gravitational-wave (GW) signals from UCXBs with LEGWORK and evaluate their detectability by space-based observatories such as Taiji and TianQin. …”
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982
Next-Generation Sequencing (NGS) in non-small cell lung carcinoma: A real-world experience in the public health system of Galicia (Northwest Spain).
Published 2025-01-01“…These results were compared with those obtained by the NGS panel to evaluate the performance of the NGS method and to identify potential novel mutations. …”
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983
Integrated single-cell and bulk RNA sequencing analysis establishes a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in neuroblas...
Published 2025-07-01“…This study aimed to construct a CAF-related prognostic model and identify the immune status of patients with NB via single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (RNA-seq). …”
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984
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985
Mitochondrial DNA variant detection in over 6,500 rare disease families by the systematic analysis of exome and genome sequencing data resolves undiagnosed cases
Published 2025-07-01“…The mtDNA is not always specifically evaluated in patients with suspected Mendelian disease, resulting in overlooked diagnostic variants. …”
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986
Investigating the Quantification Capabilities of a Nanopore-Based Sequencing Platform for Food Safety Application via External Standards of Lambda DNA and Lambda Spiked Beef
Published 2024-10-01“…The goal of this project was to evaluate the quantitative capabilities of the real-time NGS Oxford Nanopore Technologies’ MinION sequencer through a shotgun-based sequencing approach. …”
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987
Metagenomic next-generation sequencing (mNGS) versus tissue culture technique (TCT) in diagnosis of spinal infection: a systematic review and meta-analysis
Published 2025-07-01“…Traditional Tissue Culture Technique (TCT) has limitations, while Metagenomic Next-Generation Sequencing (mNGS) has emerged as a promising diagnostic tool. …”
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988
Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study
Published 2025-05-01“…This study was assigned to explore the association between early microbiological responses defined by quantitative targeted amplicon-based next-generation sequencing (QtNGS) and clinical outcomes in patients with Acinetobacter baumannii-dominant VA-LRTI.Measurements and main resultsA prospective observational study including 34 participants was conducted to assess the probability of predicting clinical outcomes using sequencing-based early microbiological response. …”
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989
Analysis of Genetic Diversity and Core Germplasm Construction of <i>Castanea crenata</i> Siebold and Zucc. Using Simple Sequence Repeat Markers and Morphological Traits
Published 2025-06-01“…This study investigates the taxonomic status, phylogenetic relationships, and genetic diversity of Japanese chestnut (<i>Castanea crenata</i> Siebold & Zucc.) in Liaodong, China, and across East Asia. Additionally, it evaluates core germplasm resources through cluster and population structure analyses using simple sequence repeat (SSR) marker data from 13 <i>Castanea henryi</i>, <i>18 Castanea seguinii</i>, and 27 <i>Castanea mollissima</i>, and 142 Japanese chestnut resources. …”
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990
Deciphering the role of SEMA4A/MAPK signaling in sepsis: insights from Mendelian randomization, transcriptomic, single-cell sequencing analyses, and vitro experiments
Published 2025-07-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were conducted to elucidate the functional pathways of core genes. Single-cell RNA sequencing (scRNA-seq) analysis was employed to evaluate gene expression profiles across various cell types in sepsis. …”
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991
Medical students’ perception of supervision in MedUniVienna’s structured internal medicine and surgery clerkship program: Subject-specific differences and clerkship sequence effect...
Published 2025-02-01“…The effect of different clerkship sequences on students' impressions of clinical supervision remains unclear. …”
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992
Probiotic characteristics and whole genome sequencing of Pediococcus pentosaceus SNF15 and its protective effect on mice diarrhea induced by Escherichia coli K99
Published 2025-03-01“…Finally, 16S rRNA sequencing was performed to compare the composition and relative abundance of the gut microbiota among the different groups. …”
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993
The administration sequences of immune checkpoint inhibitors and chemotherapy cause discrete efficacy when treating non-small cell lung cancer: a retrospective study
Published 2025-04-01“…Patients were categorized into the concurrent, immune-chemo, and chemo-immune groups based on different sequences of treatment administration. The primary endpoints evaluated were survival and treatment efficacy. …”
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994
Single-cell RNA sequencing via endoscopic ultrasound-guided fine-needle biopsy for pancreatic tumors uncovered an aggressive subclone with a poor prognosis
Published 2025-03-01“…Background: Single-cell RNA sequencing (scRNA-seq) is a powerful tool which can unveil regulatory connections between genes and cells. …”
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995
Genome-Wide Association Study of Birth Wool Length, Birth Weight, and Head Color in Chinese Tan Sheep Through Whole-Genome Re-Sequencing
Published 2024-12-01“…In this study, the phenotypic traits of wool length, birth weight, and head coat color were evaluated in 256 Chinese Tan sheep breeds. Whole genome sequencing generated 23.67 million high-quality SNPs for genome-wide association studies (GWAS). …”
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996
Lightweight photovoltaic modules technologies: reliability evaluation and market opportunity
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997
Comprehensive analysis of single-cell and bulk RNA sequencing data unveils antigen-presenting and processing fibroblasts and establishes a predictive model in gastric cancer
Published 2025-06-01“…Methods Bioinformatics analysis was conducted using single-cell and bulk RNA sequencing datasets of GC retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases. …”
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998
Diagnostic Performance of Clinical Metagenomic Next-Generation Sequencing for Suspected Central Nervous System Infections in a Municipal Hospital: A Retrospective Study in China
Published 2025-05-01“…The diagnostic performance of CSF mNGS, conventional microbiological tests (CMT), and the combination of CSF mNGS and CMT were evaluated by comparing to the final diagnosis.Results: Among 52 suspected CNSi patients, 35 were diagnosed as CNSi. …”
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999
RNA sequencing reveals dynamic expression of genes related to innate immune responses in canine small intestinal epithelial cells induced by Echinococcus granulosus protoscoleces
Published 2024-11-01“…Therefore, this study aimed to evaluate gene transcription patterns in canine small intestinal epithelial cells (CIECs) following stimulation by E. granulosus protoscoleces (PSCs). …”
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1000
Specific Technique for Examination of Industrial Equipment in Forensic Commodity Evaluation
Published 2020-04-01Get full text
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