Dual-platform integration of HPTLC and firefly algorithm-optimized chemometrics with hammersley sequence sampling for simultaneous quantification of bisoprolol, amlodipine, and mut... by Lateefa A. Al-Khateeb, Ahmed Emad F. Abbas, Mohamed R. Elghobashy, Nisreen F. Abo Talib, Ibrahim A. Naguib, Mohammed Alqarni, Michael K. Halim

“…The FA-PLS model incorporated a novel Hammersley Sequence Sampling (HSS) strategy for validation set construction, ensuring uniform concentration space coverage and eliminating sampling bias inherent in conventional random approaches. …”
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Targeted Next-Generation Sequencing Identified Compound Heterozygous Mutations in MYO15A as the Probable Cause of Nonsyndromic Deafness in a Chinese Han Family by Longhao Wang, Lin Zhao, Hu Peng, Jun Xu, Yun Lin, Tao Yang, Hao Wu

“…This study is aimed at identifying the genetic cause of congenital hearing loss in a Chinese Han family. Auditory evaluation before and after cochlear implantation and targeted next-generation sequencing of 140 deafness-related genes were performed for the deaf proband. …”
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COMPARISON MEASUREMENT AND CALCULATION OF BRAIN TUMOR IN MRI MODALITIES UTILISING SPIN-ECHO PULSE SEQUENCE T1-WEIGHTED CONTRAST AND DIGITAL IMAGE PROCESSING APPLICATIONS by Maizza Nadia Putri, Kusworo Adi, M.Irwan Katili, Sidin Hariyanto, Dwi Rochmayanti

“…Background: Evaluation of brain tumor MRI image results performed by radiologists employing the linear measurement method has several weaknesses and is sensitive to subjectivity. …”
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Exome sequencing identifies a homozygous splice site variant in RP1 as the underlying cause of autosomal recessive retinitis pigmentosa in a Pakistani family by Abdur Rashid, Asad Munir, Muhammad Zahid, Mukhtar Ullah, Atta Ur Rehman

“…Clinical examinations included visual acuity test, visual field, fundoscopy, and ocular coherence tomography (OCT). Whole exome sequencing (WES) was performed on the proband’s DNA, and Sanger sequencing was performed to validate the WES findings. …”
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Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay by Julia Faillace Thiesen, Elise Jacquemet, Pascal Campagne, Denis Chatelain, Etienne Brochot, Yves-Edouard Herpe, Nolwenn M. Dheilly, Fabrice Bouilloux, Bénédicte Rognon, Alexandre Douablin, Guillaume Leboucher, Florent Percher, Marc Eloit, Philippe Pérot

“…Further performance evaluation remains to be done on larger and prospective cohorts.…”
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Safety assessment of a novel marine multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 according to phenotype and whole genome-sequencing analysis by Xueyan Mo, Mengcheng Zhou, Yanmei Li, Lili Yu, Huashang Bai, Peihong Shen, Xing Zhou, Haojun Zhu, Huijie Sun, Ru Bu, Chengjian Jiang

“…The application of microorganisms as probiotics is limited due to lack of safety evaluation. Here, a novel multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 with aroma-producing properties was identified from marine mangrove microorganisms. …”
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Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using s... by Zhaorui Cheng, Xiangyu Yang, Yi Ren, Huimin Wang, Qi Zhang, Sailing Lin, Wenhao Wu, Xiaolu Yang, Jiahan Zheng, Xinzhu Liu, Xin Tao, Xiaoyong Chen, Yuxin Qian, Xiushen Li

“…This study aims to investigate these mechanisms using single-cell RNA sequencing data. Methods: Single-cell RNA sequencing data from HCC patients were obtained from the GEO database. …”
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Next-generation sequencing in early-stage multiple primary lung cancer: The prognostic significance of genomic accumulation status and BCL2L11del by Mu-Ting Wang, Chen-Hui Ni, Yan-Qi Lu, Wei Zheng, Shu-Liang Zhang, Mao-Hui Chen, Bin Zheng, Chun Chen

“…Clinical variables were collected, and the NGS sequencing of a large panel of 116 tumor-associated genes was performed. …”
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Physics-Informed Fast Transient Stability Assessment of Non-Fixed Length in Power Systems by LI Xiang, CHEN Siyuan, ZHANG Jun, KE Deping, GAO Jiemai, YANG Huanhuan

“…To address this, a new transient power angle stability evaluation method is proposed for power systems with grid-forming new energy based on the physics-informed sequence-to-sequence (PI-seq2seq) neural networks and cascaded convolutional neural networks models. …”
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Genetic Evaluation of Children with Global Developmental Delay—Current Status of Network Systems in Taiwan by Yong-Lin Foo, Julie Chi Chow, Ming-Chi Lai, Wen-Hui Tsai, Li-Chen Tung, Mei-Chin Kuo, Shio-Jean Lin

“…This review article aims to introduce the screening and referral network of genetic evaluation for children with developmental delay in Taiwan. …”
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Human motion similarity evaluation based on deep metric learning by Yidan Zhang, Lei Nie

“…Action feature vectors independent of camera viewpoint and human skeleton structure are extracted in the low-dimensional dense spaces, and motion similarity metrics are performed based on these features, thereby effectively eliminating the effects of camera viewpoint and human skeleton size differences on motion similarity evaluation. Specifically, when extracting the action information feature vectors using the automatic encoder-decoder network model, a sliding window method is used to divide the key point sequences of each limb part into sequence patches, and the action information feature vectors independent of the camera viewpoint and skeleton structure are extracted in a smaller time unit, so as to obtain a more refined action similarity evaluation result. …”
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SOLUTION TO EVALUATION PROBLEM OF HIDDEN SEMI-MARKOV QP-MODELS by V. M. Deundyak, M. A. Zhdanova

“…That is the selection problem based on the recorded in the data channel model error sequence from the base of hidden semi-Markov QP-models that generates the closest to the channel sequence error streams. …”
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Minor variant detection in amplicons using 454 massive parallel pyrosequencing: experiences and considerations for successful applications by Ina Vandenbroucke, Herwig Van Marck, Peter Verhasselt, Kim Thys, Wendy Mostmans, Stéphanie Dumont, Veerle Van Eygen, Katrien Coen, Marianne Tuefferd, Jeroen Aerssens

“…Furthermore, because accuracy of the DNA polymerase is vital for reliable UDS results, a comparative analysis of error profiles from seven different DNA polymerases was performed and experimentally as-sessed in parallel by 454 sequencing. Finally, intra and interrun variability evaluation of the 454 sequencing protocol revealed highly reproducible results in amplicon-based UDS.…”
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Targeted Next-Generation Sequencing of Plasma DNA from Cancer Patients: Factors Influencing Consistency with Tumour DNA and Prospective Investigation of Its Utility for Diagnosis. by Pamela J Kaisaki, Anthony Cutts, Niko Popitsch, Carme Camps, Melissa M Pentony, Gareth Wilson, Suzanne Page, Kulvinder Kaur, Dimitris Vavoulis, Shirley Henderson, Avinash Gupta, Mark R Middleton, Ioannis Karydis, Ioannis Karydis, Denis C Talbot, Anna Schuh, Jenny C Taylor

“…We investigate a next-generation sequencing approach for mutation detection in ctDNA in two related studies using a targeted panel. …”
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Infiltrating B-cell subtypes and associated hub genes in nasopharyngeal carcinoma identified from integrated single-cell, bulk RNA-sequencing, and immunohistochemical data by Fangyan Zhong, Junjun Chen, Tianzhu Lu, Lin Zhang, Zhiliang Liu, Chunhong Guan, Xiaopeng Xiong, Xiaochang Gong, Jingao Li

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High-flow nasal cannula for pre- and apneic oxygenation during rapid sequence induction intubation in emergency surgery: A systematic review and meta-analysis. by Hong Tang, Yanyan Yang, Hong Li

“…<h4>Background</h4>Rapid sequence induction intubation (RSII) is commonly used in emergency surgeries for patients at high risk of aspiration. …”
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Costs of biomarker testing in advanced non‐small cell lung cancer: a global study comparing next‐generation sequencing and single‐gene testing by Umberto Malapelle, Chien‐Chin Chen, Enrique deÁlava, Paul Hofman, Daniel Kazdal, Tae‐Jung Kim, Tony Kiat Hon Lim, Aleš Ryška, Angelica A Saetta, Ed Schuuring, Giancarlo Troncone, Michele Biscuola, Yi‐Lin Chen, Gek San Tan, Charles Hugo Marquette, Maria Michelli, Arja terElst, Hana Vošmiková, Joshua Kapp, Sebastian Gonzalez‐McQuire, Andromachi Giannopoulou, Jean Marie Franzini, Victoria Lucia Rabsiun Aramburu, Anna Baggi, Albrecht Stenzinger

“…Abstract Current European/US guidelines recommend that molecular testing in advanced non‐small cell lung cancer (aNSCLC) be performed using next‐generation sequencing (NGS). However, the global uptake of NGS is limited, largely owing to reimbursement constraints. …”
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Improved image quality and reduced acquisition time in prostate T2-weighted spin-echo MRI using a modified PI-RADS-adherent sequence by Stephen J. Riederer, Eric A. Borisch, Adam T. Froemming, Roger C. Grimm, Sara Hassanzadeh, Akira Kawashima, Naoki Takahashi, John Thomas

“…The adherent and modified sequences were evaluated in phantoms and 62 consecutive prostate MRI subjects. …”
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Application value of long-read sequencing in full characterization of thalassemia-associated structural variations: identifying a novel large segmental duplication and literature r... by Zeyan Zhong, Ganwei Zheng, Dina Zhu, Yongqiong Liu, Zezhang Lin, Zhiyang Guan, Fu Xiong, Jianhong Chen, Xuan Shang

“…Results A novel large duplication (αααα280) was identified using LRS technique and validated by Sanger sequencing. Additionally, we conducted a systematic review of known SVs and evaluated the advantages and disadvantages of various methods in analyzing complex SVs. …”
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The Grain Protein Content of Polish Cereals Other than Wheat: Can It Be Increased by Combining a Crop Sequence System, Cultivar Selection, and Plant Protection? by Marta K. Kostrzewska, Magdalena Jastrzębska

“…The GPCs of winter rye, winter triticale, spring barley, and spring oats grown in 2018–2022 in northeast Poland were evaluated to determine the influence of the crop sequence system (continuous monocropping, crop rotation), cultivar (two for each species), plant protection level (control treatment, herbicide, herbicide, and fungicide), and interactions among these factors. …”
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