Targeted next-generation sequencing enhances precision and rapid detection in healthcare-associated infection Surveillance: Unveiling multidrug-resistant colonization in ICUs by Tangchun Liu, Shuyan Deng, Wandi Liu, Jinzhao Zhang, Pengfei Wang, Zhengfei Yang

“…Objectives: This study aims to evaluate the potential advantages of targeted next-generation sequencing (tNGS) over conventional bacterial culture methods for pathogen detection in hospital-associated infections (HAIs). …”
Get full text

Study on Hydrocarbon Accumulation Periods Based on Fluid Inclusions and Diagenetic Sequence of the Subsalt Carbonate Reservoirs in the Amu Darya Right Bank Block by Yunpeng Shan, Hongjun Wang, Liangjie Zhang, Penghui Su, Muwei Cheng, Zhenhua Bai

Get full text

Complete sequencing of the mitochondrial genome of tea plant Camellia sinensis cv. ‘Baihaozao’: multichromosomal structure, phylogenetic relationships, and adaptive evolutionary an... by Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zixu Wang, Zixu Wang, Zixu Wang, Zixu Wang, Wei Zhou, Wei Zhou, Wei Zhou, Wei Zhou, Sijie Liu, Sijie Liu, Sijie Liu, Sijie Liu, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yihui Gong, Yihui Gong, Yihui Gong, Yihui Gong

“…It systematically unveils its multi-chromosomal structure, RNA editing patterns, and adaptive evolutionary mechanisms, providing critical theoretical insights into the structural complexity and evolutionary mechanisms of the tea plant mitochondrial genome.MethodsThe mitochondrial genome was fully analyzed using genome sequencing and annotation techniques. RNA editing sites were predicted to evaluate editing patterns. …”
Get full text

CEBPA-associated familial acute myeloid leukemia mimicking Werner syndrome: a case report by Tanguy Demaret, Damien Feret, Barbara Lambert, Delphine Pranger, Jean-Louis Dargent, Maria Dolores Martin Martinez, Antonio Renda, Isabelle Maystadt, Isabelle Maystadt

“…We report a 41-year-old man referred for medical genetic evaluation because of 3 synchronous tumors (colon, kidney, and thyroid) and premature aging. …”
Get full text

The audit of the teaching programs of French as a foreign language: The case of the Department of French at the University of Salahaddin, Erbil. by Ali Saleh Malo

Get full text

On evaluating MHC-II binding peptide prediction methods. by Yasser El-Manzalawy, Drena Dobbs, Vasant Honavar

Get full text

Algorithms for preliminary evaluation of the technical state of social buildings by Yu. V. Zazulya, O. V. Ashikhmin, D. S. Bayanov

“…The correlation between the detected damages and the type of structural elements as well as the year of building construction was revealed. A rational sequence of actions to evaluate the technical state of the structures of buildings with recommendations for their elimination has been proposed.…”
Get full text

Evaluation Of Radiomorphological Changes On Panoramic Radiography In Defense Athletes by Kübra Başaran Aslan, Burak Erdinç Aslan, Binali Çakır

“…The chronic remodeling/resorption process of the jaw is influenced by gender, genetics, systemic conditions, sequence of tooth loss, duration of edentulism and other unknown factors. …”
Get full text

Whole-Exome Sequencing Identifies a Novel POLG Frameshift Variant in an Adult Patient Presenting with Progressive External Ophthalmoplegia and Mitochondrial DNA Depletion by Justin Kurtz, Joseph Americo Fernandes, Mahesh Mansukhani, William C. Copeland, Ali B. Naini

“…Here, we report a 57-year-old female who presented with ophthalmoplegia, ptosis, muscle weakness, and exercise intolerance with a subsequent muscle biopsy demonstrating mitochondrial myopathy on histopathologic evaluation and multiple mtDNA deletions by southern blot analysis. …”
Get full text

Evaluating the Role of Content in Subjective Video Quality Assessment by Milan Mirkovic, Petar Vrgovic, Dubravko Culibrk, Darko Stefanovic, Andras Anderla

“…It is dependent on many variables, one of them being the content of the video that is being evaluated. Despite the evidence that content has an impact on the quality score the sequence receives from human evaluators, currently available VQA databases mostly comprise of sequences which fail to take this into account. …”
Get full text

Disassemblability evaluation methods for supporting easy disassembly design by Ryohei TSURUTA, Shiki IWASE, Yoshimasa KUWANO, Yasuo ASAGA, Hidekazu NISHIGAKI

“…Addressing the challenge of high disassembly costs impeding economic efficiency, an evaluation method considering economic feasibility is proposed. …”
Get full text

Evaluation of six molecular assays for the detection of Aigai virus by Styliani Pappa, Anna Papa

“…The aim of the present study was to evaluate the performance of six molecular assays to detect AIGV. …”
Get full text

Evaluating hippocampal replay without a ground truth by Masahiro Takigawa, Marta Huelin Gorriz, Margot Tirole, Daniel Bendor

“…Using this two-track paradigm, our framework selects replay events based on their temporal fidelity (sequence-based detection), and evaluates the detection performance using each event’s track discriminability, where sequenceless decoding across both tracks is used to quantify whether the track replaying is also the most likely track being reactivated.…”
Get full text

Synthesis and Evaluation of Melittin-Modified Peptides for Antibacterial Activity by Xiangxiang Xu, Hongyi Fu, Weihui Wu, Liang Zong, Dan Li, Bo Zhuang, Yelin Qi, Xiuli Qi, Ting Liang

“…Preparation and characterization of melittin-modified peptide—Using molecular simulation software, the structure of the melittin-modified peptide was adjusted to predict its activity and select the most appropriate amino acid sequence. The peptide was synthesized through solid-phase peptide synthesis employing the Fmoc strategy and subsequently purified using liquid chromatography. …”
Get full text

Evaluation of Imprint and Multi‐Level Dynamics in Ferroelectric Capacitors by Sara Vecchi, Francesco Maria Puglisi, Pascal Appelt, Roberto Guido, Xuetao Wang, Stefan Slesazeck, Thomas Mikolajick, Suzanne Lancaster

Get full text

Toward precision oncology in LUAD: a prognostic model using single-cell sequencing and WGCNA based on a disulfidptosis relative gene signature by Panpan Li, Han Zhang, Limin Sun, Xiaojuan Wu

“…Gene expression in single cell RNA sequencing (scRNA-seq) data was assessed using the AUcell algorithm. …”
Get full text

NETosis-based prognostic model reveals immune modulation in clear cell renal cell carcinoma using single-cell and bulk RNA sequencing by Zijie Yu, Zihao Xu, Xi Zhang, Wenchuan Shao, Da Zhong, Xinghan Yan, Tingfei Jiang, Yichun Wang, Ninghong Song

Get full text

High tumor mutational burden assessed through next-generation sequencing predicts favorable survival in microsatellite stable metastatic colon cancer patients by Annabella Di Mauro, Mariachiara Santorsola, Giovanni Savarese, Roberto Sirica, Monica Ianniello, Alessia Maria Cossu, Anna Ceccarelli, Francesco Sabbatino, Marco Bocchetti, Anna Chiara Carratù, Francesca Pentimalli, Gerardo Ferrara, Guglielmo Nasti, Michele Caraglia, Alessandro Ottaiano

“…Comprehensive clinical and molecular profiling was conducted, including next-generation sequencing (NGS) for TMB evaluation with the TruSight Oncology® kit. …”
Get full text

High precision characterization of RCCX rearrangements in a 21-hydroxylase deficiency Latin American cohort using oxford nanopore long read sequencing by Aldana Claps, Jorge E. Kolomenski, Franco Fernández, Natalia Macchiaroli, Marina L. Ingravidi, Marisol Delea, Cecilia Fernández, Tania Castro, Julieta Laiseca, Laura Kamenetzky, Melisa Taboas, Liliana Dain

“…A total of 34 samples were sequenced in 2 amplicons of 8.5 Kb covering the centromeric and telomeric RCCX modules. …”
Get full text

Molecular genetic profiling of a rare case of primary pulmonary adenoid cystic carcinoma: Insights from whole exome sequencing and literature review by Jianhao Xu, Fang Cao, Liqian Yao, Jingfeng Gu, Lanfen Pan, Jiarui Min, Zijie Xu, Jihao Su, Zhiyong Deng, Song Xu

“…Aim: The study seeks to enhance understanding of PPACC through comprehensive analysis of a reported case, incorporating pathological diagnosis, immunohistochemistry, special staining, and molecular alterations identified via whole exome sequencing. Methods: A retrospective analysis was conducted on a PPACC case treated at the institution, encompassing pathological examination, immunohistochemical profiling, special staining techniques, and molecular alterations revealed by whole exome sequencing. …”
Get full text