L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells by Yi Kuang, Yi Kuang, Yong Jian, Yong Jian, Dinghuan Wang, Dinghuan Wang, Lihao Bai, Lihao Bai, Kunlin Yu, Kunlin Yu, Chunlin Wang, Chunlin Wang, Wuling Liu, Wuling Liu, Sheng Liu, Sheng Liu, Wan Li, Yaacov Ben-David, Yaacov Ben-David, Xiao Xiao, Xiao Xiao

“…RNA sequencing analysis revealed that differentially expressed genes (DEGs) mainly enriched in protein processing of endoplasmic reticulum (ER). …”
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Isolation and identification of pathogenic bacteria causing cut chrysan-themum receptacle browning and screening of antibacterial agents(切花菊花心褐化病原菌分离鉴定及抑菌药剂筛选)... by 胡雅鑫(HU Yaxin), 郭梓婷(GUO Ziting), 方萍(FANG Ping), 管志勇(GUAN Zhiyong), 陈素梅(CHEN Sumei), 陈发棣(CHEN Fadi), 王利凯(WANG Likai)

“…Among the 15 commonly used ecofriendly and low-toxicity antibacterial agents evaluated, 80% ethylicin emerged as the most effective, with a 1 000-time dilution significantly inhibiting receptacle browning in two other chrysanthemum cultivars. …”
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High-salt-driven gut microbiota dysfunction aggravates prostatitis by promoting AHR/SGK1/FOXO1 axis-mediated Th17 cell differentiation by Jing Chen, Rui Feng, Bin-Bin Gong, Wei-Kang Wu, Bang-Shun Dai, Rui Tan, Wen-Long Xu, Tong Meng, Xiao-Bin Wang, Yun-Zheng Xiao, Cheng Yang, Li Zhang, Chao-Zhao Liang

“…Methods Patients diagnosed with CP/CPPS were evaluated with the National Institutes of Health Chronic Prostatitis Symptom Index scoring system, and the correlation between the symptoms of CP/CPPS with HSD was analyzed. …”
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Gegen-Sangshen oral liquid and its active fractions mitigate alcoholic liver disease in mice through repairing intestinal epithelial injury and regulating gut microbiota by Shulin Wei, Mingxing Li, Long Zhao, Tiangang Wang, Ke Wu, Jiayue Yang, Yubin Liu, Yueshui Zhao, Fukuan Du, Yu Chen, Shuai Deng, Jing Shen, Zhangang Xiao, Wanping Li, Xiaobing Li, Yuhong Sun, Li Gu, Mei Wei, Zhi Li, Xu Wu

“…Lipid accumulation in hepatocytes was evaluated by oil red O staining. Ethanol metabolism was assessed by determining the activity of ADH and ALDH enzymes. …”
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Protective effects of miR-24-2-5p in early stages of breast cancer bone metastasis by Margherita Puppo, Martine Croset, Davide Ceresa, Manoj Kumar Valluru, Victor Gabriel Canuas Landero, Monserrat Hernandez Guadarrama, Michele Iuliani, Francesco Pantano, Penelope Dawn Ottewell, Philippe Clézardin

“…Endogenous miR-24-2-5p expression levels were also quantified during murine osteoclast differentiation. RNA-sequencing (RNA-seq) analysis of BC cells was performed to evaluate transcriptomic changes associated with miR-24-2-5p overexpression. …”
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Spatial Distribution of Equid Exposure to <i>Rickettsia</i> spp. in Goiás State, Midwestern Brazil by Gracielle Teles Pádua, Mariana Avelar Tavares, Nicolas Jalowitzki de Lima, Warley Vieira de Freitas Paula, Gabriel Cândido dos Santos, Lucianne Cardoso Neves, Raphaela Bueno Mendes Bittencourt, Raquel Loren dos Reis Paludo, Ennya Rafaella Neves Cardoso, Bianca Barbara Fonseca da Silva, Bruno Rodrigues de Pádua, Ana Carolina Borsanelli, Filipe Dantas-Torres, Gina Paola Polo, Felipe da Silva Krawczak

“…Of these, one <i>A. cajennense</i> s.l. specimen amplified a fragment of both the <i>omp</i>A and <i>glt</i>A genes, and one <i>A. sculptum</i> specimen amplified a fragment of the <i>glt</i>A gene through conventional PCR. Sequencing confirmed the detection of <i>R. amblyommatis</i>. …”
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Influence of different amelioration methods for replant peach orchards on phosphorus-dissolving microbial composition as well as yield and quality of yellow-fleshed peaches by WANG Qingfeng, ZHOU Deping, ZHAO Zheng, WU Shuhang, CHU Changbin

“…In addition, Illumina Miseq sequencing was applied to determine soil phosphorus-dissolving microbial composition and diversity by targeting phoD gene. …”
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Analysis of Tolerance to Heavy Metal Ions and Their Oxides on Endogenous Short-Range Denitrification Systems Domesticated by Different Valence Iron by JIN Baodan, YAN Yeyu, BAI Zhixuan, LIU Ye, WANG Baogui, DU Jingjing, PANG Long, JI Jiantao, Ma Chuang

“…The research tried to domesticate the EPD system using various valence states of iron, namely nanoscale zero-valent iron (nZVI), ferrous ions (Fe²⁺), and ferric ions (Fe³⁺), and evaluated its response to different heavy metal ions and their nano-oxides, including CuSO₄, ZnSO₄, nano-CuO, and nano-ZnO.MethodsThe study utilized a 10-liter sequencing batch reactor (SBR) to construct the EPD system, with four distinct setups: a control system (S1), and systems supplemented with nZVI (S2), Fe²⁺ (S3), and Fe³⁺ (S4). …”
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Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomizatio... by Xiaoxiao Zhao, Jiannan Li, Shaodi Yan, Yu Tan, Runzhen Chen, Nan Li, Jinying Zhou, Chen Liu, Peng Zhou, Yi Chen, Hongbing Yan, Hanjun Zhao, Li Song

“…Methods Deep-targeted sequencing employing a unique molecular identifier (UMI) for the analysis of 42 CHIP mutations—achieving an impressive mean depth of coverage at 1000 × —was conducted on a cohort of 1430 patients diagnosed with acute myocardial infarction (473 patients with T2DM and 930 non-DM subjects). …”
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Clinical study on compound glycyrrhizin injection wet compress for wounds healing after Hemoporfin-mediated photodynamic therapy for port-wine stains (复方甘草酸苷注射液湿敷治疗鲜红斑痣海姆泊芬光动力术后创面的... by DAI Hongmei (代红梅), HUO Ruiling (霍瑞玲), ZHOU Yanhua (周燕华), HUANG Xiuying (黄秀英), XU Weilun (徐伟伦)

“…Methods A prospective, randomized controlled study design was used to assign patients to trial and control groups in a 1: 1: 1 ratio by computer-generated randomization sequences, and evaluators were blinded (unaware of grouping information) for outcome determination. …”
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全基因组关联分析标准化流程的构建与扩展应用(Development and Extended Applications of Standardized Processes for Genome-Wide Association Studies) by 许喆1，2，石延枫1，2，张杰1，2，姜明慧1，2，刘阳1，2，李昊1，2，3，廖晓凌4，程丝1，2，3(XU Zhe1,2, SHI Yanfeng1,2, ZHANG Jie1,2, JIANG Minghui1,2, LIU Yang1,2, LI Hao1,2,3, LIAO Xiaoling4, CHENG Si1,2,3)

“…The quality of GWAS was evaluated by the genome inflation coefficient and quantile-quantile plots. …”
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Impact of short-term aircraft noise on cardiovascular disease risk in the area surrounding London Heathrow airport: the RISTANCO epidemiological study by Xiangpu Gong, Nicole Itzkowitz, Calvin Jephcote, Kathryn Adams, Glory O Atilola, John Gulliver, Marta Blangiardo, Anna Hansell

“…We provided input data for the model such as temperature and evaluated outputs against annual average Civil Aviation Authority (CAA) noise levels (that use the ANCON noise model). …”
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