Modelling soil prokaryotic traits across environments with the trait sequence database ampliconTraits and the R package MicEnvMod by Jonathan Donhauser, Anna Doménech-Pascual, Xingguo Han, Karen Jordaan, Jean-Baptiste Ramond, Aline Frossard, Anna M. Romaní, Anders Priemé

“…We present a comprehensive, customizable workflow for inferring prokaryotic phenotypic traits from marker gene sequences and modelling the relationships between these traits and environmental factors, thus overcoming the limited ecological interpretability of marker gene sequencing data. …”
Get full text

Clinical implementation of next-generation sequencing testing and genomically-matched therapy: a real-world data in a tertiary hospital by Jin Won Kim, Hee Young Na, Sejoon Lee, Ji-Won Kim, Koung Jin Suh, Se Hyun Kim, Yu Jung Kim, Keun-Wook Lee, Jong Seok Lee, Jaihwan Kim, Jin-Hyeok Hwang, Kihwan Hwang, Chae-Yong Kim, Yong Beom Kim, Soomin Ahn, Kyu Sang Lee, Hyojin Kim, Hye Seung Lee, So Yeon Park, Gheeyoung Choe, Jee Hyun Kim, Jin-Haeng Chung

“…Abstract Next-generation sequencing (NGS) cancer profiling has gained traction in routine clinical practice in South Korea. …”
Get full text

Chromosomal instability by low-coverage whole-genome sequencing assay predicts prognosis in bladder cancer patients underwent radical cystectomy by Qi Ding, Hailiang Zhu, Bo Fan, Lisheng Wang, Xiaohua Jin, Cheng Cao, Ying Shi, Zhijiang Fan, Wenjian Tu, Feng Li

“…Abstract Purpose To investigate chromosomal instability (CIN) in tumor tissue from radical bladder resection and to evaluate whether it can be used as a biomarker for the molecular typing of (BC). …”
Get full text

Clinical application value of simultaneous plasma and bronchoalveolar lavage fluid metagenomic next generation sequencing in patients with pneumonia-derived sepsis by Jiayan Li, Dongxu Pan, Yuxin Guo, Bo Zhang, Xinglin Lu, Chen Deng, Feifei Xu, Zongnan Lv, Qinhe Chen, Yafeng Zheng, Shuhao Nong, Lihua Su, Rongfa Qin, Fufu Jiang, Wei Gai, Gang Qin

“…Abstract Background Despite the increasing use of metagenomic next-generation sequencing (mNGS) in sepsis, identifying clinically relevant pathogens remains challenging. …”
Get full text

Identification of novel metabolism-related biomarkers of Kawasaki disease by integrating single-cell RNA sequencing analysis and machine learning algorithms by Chenhui Feng, Zhimiao Wei, Xiaohui Li, Xiaohui Li

“…Identifying signature cells and genes related to BAM and FAM could offer a deeper understanding of their role in the pathogenesis of KD.MethodWe analyzed the public single-cell RNA sequencing (scRNA-seq) dataset GSE1687323 to characterize the immune cell-type landscape in KD. …”
Get full text

Single-cell sequencing-based study of ferroptosis mechanisms in heat stroke: identification of key biomarkers and dynamic analysis of the immune microenvironment by Defeng Yin, Qin Guo, Hao Jiang, Yonglan Hu, Lu Liu, Xiang Li, Chenglin Wang, Shilin Li, Kaiyu Jin, Yingchun Hu

“…Methods Peripheral blood samples from 29 heat stroke patients, recruited at an early stage of the condition, underwent transcriptome sequencing, and single-cell RNA sequencing was conducted for two representative cases. …”
Get full text

Unraveling the significance of cuproptosis in hepatocellular carcinoma heterogeneity and tumor microenvironment through integrated single-cell sequencing and machine learning appro... by Wang Liu, Liangjing Xia, Yuan peng, Qiang Cao, Ke Xu, Huiyan Luo, Yongjun Peng, Yanping Zhang

“…The GSVA method was applied to evaluate the activity of 18 programmed cell death pathways. …”
Get full text

Differential Analysis of Oral Microbiota in db/db Mouse Model of Type 2 Diabetes Utilizing 16S rRNA Sequencing by PAN Qianjia, GE Junyi, HU Nan, HUA Fei, GU Min

“…The composition of the oral microbiota was evaluated through double-labelled amplification and sequencing on the Illumina MiSeq platform, followed by bioinformatics analysis using QIIME software(version 1.6.0).ResultsThe FBG levels and OGTT results on the 6th and 37th days after the start of the experiment indicated that db/db mice exhibited more pronounced symptoms of type 2 diabetes compared to db/m mice. …”
Get full text

Patient-Related Metadata Reported in Sequencing Studies of SARS-CoV-2: Protocol for a Scoping Review and Bibliometric Analysis by Karen O'Connor, Davy Weissenbacher, Amir Elyaderani, Ebbing Lautenbach, Matthew Scotch, Graciela Gonzalez-Hernandez

“… BackgroundThere has been an unprecedented effort to sequence the SARS-CoV-2 virus and examine its molecular evolution. …”
Get full text

Automated quantification of T1 and T2 relaxation times in liver mpMRI using deep learning: a sequence-adaptive approach by Lukas Zbinden, Samuel Erb, Damiano Catucci, Lars Doorenbos, Leona Hulbert, Annalisa Berzigotti, Michael Brönimann, Lukas Ebner, Andreas Christe, Verena Carola Obmann, Raphael Sznitman, Adrian Thomas Huber

“…Abstract Objectives To evaluate a deep learning sequence-adaptive liver multiparametric MRI (mpMRI) assessment with validation in different populations using total and segmental T1 and T2 relaxation time maps. …”
Get full text

MRI-based pseudo-CT sequences as a radiation-free alternative to CT for obstetric pelvimetry: a proof-of-concept study by Caroline Chabot, Mathilde Haegeman, Eya Chaouch, Dana Dumitriu, Renaud Menten, Patricia Steenhaut, Pierre Bernard, Perrine Triqueneaux, Nicolas Michoux, Frédéric E. Lecouvet

“…This proof-of-concept study evaluates the reliability of these sequences and the agreement with CT for pelvimetry in a predominantly elderly population. …”
Get full text

The Role of Applying Metagenomic Next-Generation Sequencing (mNGS) in Periprosthetic Joint Infection with Sinus Tract: A Retrospective Study by Yuan X, Wang Q, Ding H, Li H, Fang X, Zhang W, Huang Z

“…Metagenomic next-generation sequencing (mNGS) offers a culture-independent diagnostic approach. …”
Get full text

Evaluation of the Manipulation Potential of the Internet in the Political Sphere by V. V. Borshchenko

Get full text

Performance Evaluation of MRMED Algorithm by Monitoring BER by SYED RIZWAN-UL-HASAN, Muhammad Tahir

Get full text

Evaluation of the Transparency of the Medical Insurance System in Ukraine by Oleksii Zakharkin, Liudmyla Zakharkina, Paulina Srovnalikova, Volodymyr Novikov, Iryna Basanets

Get full text

Comparison of different magnetic resonance cholangiography techniques in living liver donors including Gd-EOB-DTPA enhanced T1-weighted sequences. by Sonja Kinner, Verena Steinweg, Stefan Maderwald, Arnold Radtke, Georgios Sotiropoulos, Michael Forsting, Tobias Schroeder

“…<h4>Conclusions</h4>3D T2w sequences are essential for preoperative biliary tract evaluation in potential living liver donors. …”
Get full text

Revealing the Next Word and Character in Arabic: An Effective Blend of Long Short-Term Memory Networks and ARABERT by Fawaz S. Al-Anzi, S. T. Bibin Shalini

Get full text

Histometric evaluation of testis in rabbits treated with Silymarin by Raghda Nazar, Ahmed S. Al-A&amp;acute;Araji

Get full text

Can whole-body diffusion-weighted magnetic resonance sequence replace 18F-fluorodeoxyglucose-positron emission tomography in the management of lymphoma? by Rafik M. Ibrahim, Mwanajaa Abdalla Mwachui, Ahmed El-Gowily, Azza Mohamed Amin Darwish

“…The aim of this study was to assess the role of whole-body diffusion-weighted MR sequence in management of lymphoma, compared to conventional FDG-PET CT, as well as to ascertain whether WB-DW-MRI is a good alternative to FDG PET/ CT for the diagnosis of lymphoma and subsequent treatment evaluation. …”
Get full text

Evaluation of the antinociceptive potential of sodium valproate in mice by Lidia Cristina Chitac, Sorin Beschea, Monica Neamtu, Delia Bulea, Veronica Bild

Get full text