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8301
Worldwide Research Trends on Lung Cancer and Microbiota: A Bibliometric and Visualized Analysis
Published 2025-07-01“…To provide an overview, annual publications, countries/regions, and keywords were evaluated through a bibliometric analysis, and extracted and analyzed key clinical information.Results: A total of 579 publications were reviewed, with 177 clinical studies chosen for detailed analysis. …”
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8302
New submodel for emissions from Explosive Volcanic ERuptions (EVER v1.1) within the Modular Earth Submodel System (MESSy, version 2.55.1)
Published 2025-07-01“…This setup was successfully evaluated with satellite observations of stratospheric <span class="inline-formula">SO<sub>2</sub></span> burden and aerosol optical properties. …”
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8303
Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating &alpha;7nAChR in a Rat Model of Asphyxial Cardiac Arrest
Published 2025-07-01“…An oxygen-glucose deprivation/reoxygenation (OGD/R) model of primary microglia was established to confirm the role of α 7nAChR in inhibiting pyroptosis.Results: Single-cell RNA sequencing of rat brain and immunofluorescent co-localization showed that pyroptosis is principally occurred in microglia rather than neurons, astrocytes, oligodendrocytes, or endothelial cells in CA/CPR rats. …”
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8304
Magnesium ions regulate the Warburg effect to promote the differentiation of enteric neural crest cells into neurons
Published 2025-01-01“…Non-targeted metabolomic sequencing, cellular acidification rate, oxygen consumption, and western blot analyzed sugar metabolism changes. …”
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8305
Lonafarnib Protects Against Muscle Atrophy Induced by Dexamethasone
Published 2025-02-01“…Muscle function was evaluated by grip strength and compound muscle action potential (CMAP) in the gastrocnemius (GC) and tibialis anterior (TA) muscles. …”
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8306
Association of a Sulfur-Containing Diet and a CTH Polymorphism with Bone Density in the Uyghur Population of China: A Preliminary Study
Published 2025-06-01“…Skeletal health of the calcaneus was evaluated using quantitative ultrasound scanning.Results: The study included a total of 200 participants, comprising 81 males and 119 females. …”
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8307
Novel Classification of Peroneal Tendon Disease Reveals Cellular and Molecular Phenotypes of the Tenosvnovium
Published 2024-12-01“…A qualitative assessment evaluated the cell spatial distribution relative to tissue structures (e.g., fat, fibrous tissue, and vascularity). …”
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8308
Combined microbial inoculation and reduced inorganic fertilization enhances diversity and functionality in potato rhizosphere microbiome at field scale
Published 2025-08-01“…Microbial community composition and diversity were assessed using sequencing data and estimated absolute abundance. The functional potential of the soil microbiome was evaluated by quantifying key genes involved in carbon and nitrogen biogeochemical cycles via quantitative PCR. …”
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8309
Facial sensory symptoms in medullary infarcts Sintomas sensitivos na face em infartos medulares
Published 2005-12-01“…All patients were submitted to conventional brain MRI including axial T1-, T2-weighted and Fluid attenuated inversion-recovery (FLAIR) sequences. MRIs were evaluated blindly to clinical features to determine extension of the infarct to presumed topographies of the ventral trigeminothalamic (VTT), lateral spinothalamic, spinal trigeminal tracts and spinal trigeminal nucleus. …”
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8310
LINC02888 promotes HGSOC progression and immune evasion via PPIB-mediated stabilization of LAPTM5 mRNA and inhibition of RIG-I-like receptor signaling
Published 2025-06-01“…The effect on the RIG-I–like receptor pathway was evaluated by measuring the expression levels of RIG-I, IRF7, and ISG15. …”
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8311
A Monocyte-Driven Prognostic Model for Multiple Myeloma: Multi-Omics and Machine Learning Insights
Published 2025-06-01“…Next, MM patients with the low MGPS score exhibiting significantly better overall survival (OS) than the high MGPS score (p< 0.0001). Finally, we evaluated the predictive value of MGPS for treatment response and explored its molecular mechanisms. …”
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8312
Estimating the effect of South Africa travel restrictions in November 2021 on the SARS-CoV-2 Omicron outbreak in the Netherlands: a descriptive analysis and modelling study
Published 2025-05-01“…In the Netherlands, direct flights from South Africa were banned from 26 November 2021 onwards to curb Omicron (B.1.1.529) importation.Objectives This study retrospectively evaluated the effect of the South African travel ban and the timing of its implementation on subsequent Omicron infections in the Netherlands and, in order to help inform future decision-making, assessed alternative scenarios in which the reproduction number (Re) and volume of indirectly imported cases were varied.Design Descriptive analysis and modelling study.Outcome measure Time (days) from 26 November 2021 to reach 10 000 cumulative Omicron infections in the Netherlands.Methods To benchmark the direct importation rate of Omicron from South Africa, we used the proportion (n/N, %) of passengers arriving on two direct flights from South Africa to the Netherlands on 26 November 2021 with a positive PCR sequencing result for Omicron VoC infection. …”
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8313
Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result
Published 2025-03-01“…A BALB/c-derived xenograft mouse model was established to evaluate the functional role of MyD88 in tumor progression and immunotherapy response. …”
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8314
Exosomes Derived from Apelin-Pretreated Mesenchymal Stem Cells Ameliorate Sepsis-Induced Myocardial Dysfunction by Alleviating Cardiomyocyte Pyroptosis via Delivery of miR-34a-5p
Published 2025-01-01“…Cardiomyocyte pyroptosis was determined by TUNEL staining. RNA sequencing was used to identify differentially expressed functional miRNAs between MSC-EXOs and Apelin-MSC-EXOs. …”
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8315
Differential Gut Microbiome Profiles in Long-Distance Endurance Cyclists and Runners
Published 2024-12-01“…Fecal samples were obtained and subjected to taxonomic analysis to assess the relative abundances of species across subjects based on 16S rRNA sequencing results. Both alpha and beta diversity of the bacterial communities were evaluated to identify compositional variations between the groups. …”
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8316
Recurrence Prediction by Multi-Omics in the Patient with Colorectal Peritoneal Metastases After Cytoreductive Surgery: A Prospective Biomarker Study
Published 2025-04-01“…., Ltd, Guangzhou, Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Da Wang, Department of Colorectal Surgery and Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China, Tel +86-571-87784720, Email wangda0618@zju.edu.cn Lifeng Sun, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang, 310009, People’s Republic of China, Tel +86-571-87783586, Email sunlifeng@zju.edu.cnBackground: Colorectal cancer with peritoneal metastases (CRCPM) exhibits high recurrence post-cytoreductive surgery (CRS). This study evaluated tumor tissue biomarkers and combined circulating tumor DNA (ctDNA) and methylation analysis via ultra-deep next-generation sequencing (NGS) for recurrence prediction.Methods: CRCPM patients undergoing surgery were enrolled (n=21). …”
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8317
Study on the Influence and Mechanism of Resveratrol on Cognitive Impairment in Chronic Kidney Disease Rats Through Regulating Gut Microbiota and the TLR4/NF&kappa;B Pathway
Published 2025-05-01“…Serum Interleukin-6 (IL-6), Tumor Necrosis Factor-alpha (TNF-α), and Lipopolysaccharide (LPS) levels were measured via ELISA. Histopathology evaluated kidney, colon, and hippocampal damage. Gut microbiota composition was analyzed by 16S rRNA sequencing, and hippocampal Toll-Like Receptor 4 (TLR4)/ the Nuclear Factor-κB (NFκB) pathway proteins were quantified via Western blot.Results: CKD groups exhibited elevated 24-hour urinary albumin, serum urea nitrogen, and creatinine (P < 0.01), with glomerular atrophy. …”
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8318
MiRNAs and Neutrophil-Related Membrane Proteins from Plasma-Derived Extracellular Vesicles for Early Prediction of Organ Dysfunction and Prognosis in Septic Patients
Published 2024-12-01“…We performed miRNA sequencing of the isolated EVs, followed by bioinformatic analysis. …”
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8319
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers
Published 2025-03-01“…Co-cultures of TMPRSS2 model systems with blood peripheral mononuclear cells were employed to evaluate immune cell migration, cytotoxicity and cytokine release. …”
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8320
Cinobufagin Suppresses Lipid Peroxidation and Inflammation in Osteoporotic Mice by Promoting the Delivery of miR-3102-5p by Macrophage-Derived Exosomes
Published 2024-10-01“…MicroCT, HE staining, and TRAP staining were employed to evaluate bone mass and therapeutic outcomes, while mRNA sequencing and immunoblotting were utilized to assess markers of bone metabolism, inflammation, and lipid peroxidation. …”
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