Experience in Diagnostic of HIV Drug Resistance in the Mekong Delta Region, Vietnam: A Comparative Analysis Before and After the COVID-19 Pandemic by Huynh Hoang Khanh Thu, Alexandr N. Schemelev, Yulia V. Ostankova, Vladimir S. Davydenko, Diana E. Reingardt, Ton Tran, Le Chi Thanh, Thi Xuan Lien Truong, Areg A. Totolian

“…HIV-1 genotyping and mutation detection were performed based on an analysis of the nucleotide sequences of the <i>Pol</i> gene region. A total of 116 HIV-infected individuals with virological failure in 2019 and 2022 were assessed for HIV drug resistance. …”
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Clonorchis sinensis-driven hepatocarcinogenesis via E2F1-CD24 transcriptional axis: mechanistic and therapeutic implications by Wen-Min Lu, Jin Yan, Zhao-Ji Liu, Yong Wu, Qian-Ru Cui, Ji Feng, Yu Chen, Guang-Zhi Zhu, Tao Peng, Jing Zhou, Guo-Dong Lu

“…Preliminary single-cell sequencing revealed marked overexpression of cluster of differentiation 24 (CD24) in HCC tissues, suggesting its potential pathological role. …”
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Análisis del estilo de juego de dos equipos entrenados por ‘Pep’ Guardiola (Analysis of the playing style of two teams coached by ‘Pep’ Guardiola) by Luis Pueyo Romeo, Víctor Murillo Lorente, Javier Álvarez Medina, Mario Amatria Jiménez

“…Various variables were assessed to define their playing style, utilizing descriptive statistics and a quantitative analysis (χ²) to evaluate the differences between both teams. The results reveal significant differences in the construction of offensive sequences between them. …”
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TLR4/MyD88 expression patterns and novel genetic variants: association with aggressive clinicopathological features in colorectal cancer by Thai Tra Dang, Thai Tra Dang, Viet Nhat Pham, Ngoc Dung Tran, Thu Hang Ngo, Van Mao Can, Huy Hoang Nguyen, Thi Xuan Nguyen, Thanh Chung Dang

“…DNA sequencing identified genetic variants in TLR4 and MyD88 genes. …”
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Circular RNA circ-Olfm1 induces progression of Alzheimer’s disease by regulating FOXO3a by YANG Hongyan, LIAO Qirong, HOU Mingliang

“…In starBase database, there are complementary sequences observed between circ-Olfm1 and miR-330-5p. …”
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Revealing the Mechanism of <i>Hemerocallis citrina</i> Baroni in Depression Treatment Through Integrated Network Pharmacology and Transcriptomic Analysis by Shan Gao, Jihui Lu, Yixiao Gu, Yaozhi Zhang, Cheng Wang, Feng Gao, Ziqi Dai, Shujing Xu, Jindong Zhang, Yuqin Yang, Haimin Lei

“…Its antidepressant effect was evaluated by chronic unpredictable mild stress (CUMS)-induced depression. …”
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Let-7a-5p derived from parathyroid hormone (1–34)-preconditioned BMSCs exosomes delays the progression of osteoarthritis by promoting chondrocyte proliferation and migration by Litao Shao, Lu Ding, Weizhao Li, Chi Zhang, Yu Xia, Miaoyu Zeng, Zhizhong Ye, David Y. B. Deng

“…Through MicroRNA (miRNA) sequencing analysis, this study aims to reveal the effects and potential mechanism of miRNA (let-7a-5p) in ExoPTH to repair OA cartilage. …”
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Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model by Cassandra M. Flynn, Tamunotonye Omoluabi, Alyssa M. Janes, Emma J. Rodgers, Sarah E. Torraville, Brenda L. Negandhi, Timothy E. Nobel, Shyamchand Mayengbam, Qi Yuan

“…While probiotics have shown cognitive benefits in amyloid-centered AD models, their effect on pretangle tau pathology remains elusive. Methods This study evaluates the effects of probiotics in a rat model of preclinical AD, specifically targeting hyperphosphorylated pretangle tau in the locus coeruleus. …”
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Kaempferol and Vitamin E Improve Production Performance by Linking the Gut–Uterus Axis Through the Reproductive Hormones and Microbiota of Late-Laying Hens by Jing Zhang, Jie Zhang, Kangle Li, Xinyue Fu, Yanhui Liang, Minling Zhang, Shaolong Zhuang, Yuyun Gao

“…This study evaluated the effects of kaempferol (KAE), and vitamin E (VE) on the performance, reproductive hormones, and the composition of the cecum and uterus microbiota in late-laying hens. …”
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Gut microbiota’s role in the enhancement of type 2 diabetes treatment by a traditional Chinese herbal formula compared to metformin by Chengdong Xia, Liya Yue, Yinyu Wang, Cuidan Li, Guannan Ma, Yingjiao Ju, Peihan Wang, Jie Wang, Xiaoyuan Jiang, Xiaotong Wang, Fei Chen

“…Comprehensive clinical indicators of T2DM were measured before and after treatment. High-throughput sequencing was used to assess changes in gut microbiome composition and function. …”
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Aurantio-obtusin modulates Wilms Tumour 1 within the breast tumour microenvironment reducing immunosuppression and tumour growth by Rui Li, Dómhnall J O’Connor, Barry Digby, Pilib Ó. Broin, Xiao Hu, Ning Ge, Paul G. Loftus, Vatsal Kumar, Eoin McEvoy, Stephen J. Elliman, Michael J. Kerin, Laura R. Barkley

“…Co-culture assays were performed to evaluate the role of CAF-derived WT1 in T cell proliferation and differentiation using flow cytometry. …”
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Serum miRNA-186-3P and miRNA-382-3P constitute a novel Diagnostic miRNA signature for palindromic rheumatism by Fangfang Yuan, Zefu Weng, Qiong Yang, Jing Luo, Lina Ying, Haiyan Huang, Xin Zhang, Yahui Chen, Jixia Lin, Junhong He

“…Using next-generation high-throughput sequencing (NGS), this study aimed to screen miRNAs specifically expressed in the serum of patients with PR to construct a miRNA signature and verify its diagnostic efficacy.MethodsPatients with PR (N=4), patients with rheumatoid arthritis (RA; N=3), and healthy individuals (Con; N=3) were included in an exploration cohort. …”
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Expression of the IL-18-related gene PTX3 correlates with clinicopathological features and prognosis in glioma patients by Delin Wang, Cuimei Liu, Bohao Sun, Xiaodong Zhang, Yejun Zhou, Zhonglin Hu, Duanzheng Cao, Jing Zhang, Jinfang Xu

“…Materials and Methods RNA sequencing data and clinical information for glioma patients were obtained from The Cancer Genome Atlas (TCGA). …”
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Analysis of Soil Fungal Community Characteristics of <i>Morchella sextelata</i> Under Different Rotations and Intercropping Patterns and Influencing Factors by Weilin Feng, Jiawen Wang, Qunli Jin, Zier Guo, Weiming Cai

“…Using Illumina NovaSeq high-throughput sequencing coupled with ecological and statistical analyses, the relative abundance, alpha diversity index, beta diversity, and intergroup differences in fungal communities were assessed. …”
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Metabolism of oxyfluorfen by actinobacteria Micrococcus sp. F3Y by Li Yao, Yue Wen, Yue Wen, Yuting Sha, Leqin Wang, Xianrui Bi, Shuhan Si, Min Shen, Shusong Zhang, Haiyan Ni

“…F3Y, an oxyfluorfen‒degrading actinobacterium, and evaluated its degradation efficiency in yeast powder‒supplemented mineral medium (YPM) medium and oxyfluorfen‒contaminated soil. …”
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Microbiome-driven gene dysregulation in oesophageal cancer: a multi-omics analysis by Chaitali Nath

“…In total, 57,500 genes were evaluated for differential expression, focusing on those correlated with oesophageal cancer-associated microbes.2,5 Differentially expressed genes (DEGs) were identified, with emphasis on immune activation and epithelial remodeling. …”
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Assessment of Microbial and Nutritional compositions of Fermented Plantain flour across the three Senatorial districts in Ogun State, Nigeria by Osiyemi, E. O., Okoh, O. A., Akindele, S. T., Raufu, T. T., Obafebi, T. O.

“…Serial dilution was employed for the total bacteria count, while identification was carried out using 16S rRNA sequencing.  Nutritional assessments of the flour samples were also evaluated using techniques to determine the crude protein, fat, fiber, ash content, and moisture content of the flour samples.  …”
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Detection of the 30-bp deletion and protein expression of Epstein-Barr virus latent membrane protein 1 in extranodal NK/T cell lymphoma and its clinicopathological significance by Xingmei Lu, Qingsong Han, Peng Li, Kate Huang, Xiuhuan Ji, Suidan Chen, Rixu Lin, Xiaoyu Wang

“…Methods The clinical and histological characteristics of 42 ENKTCL cases were retrospectively evaluated. Del-LMP1 was detected using a nested polymerase chain reaction and Sanger sequencing, while LMP1 protein expression was assessed via immunohistochemistry. …”
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Optimizing Genomic Selection Methods to Improve Prediction Accuracy of Sugarcane Single-Stalk Weight by Zihao Wang, Chengcai Xia, Yanjie Lu, Qi Liu, Meiling Zou, Fenggang Zan, Zhiqiang Xia

“…After rigorous filtering of Hyper_seq_FD sequencing data from 409 sugarcane samples, we identified 31,204 high-quality single-nucleotide polymorphisms (SNPs) evenly distributed across all 32 chromosomes, providing a comprehensive representation of the sugarcane genome. …”
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Mechanistic insights into Circ-MBOAT2-mediated regulation of TLK1 through miR-664b-3p in non-small cell lung cancer by DanTing Zhao, Cong Wang, GuangCheng Zhang, ZhengChang Song, ChunYu Luan

“…Methods Our investigation focused on the interplay among circ-MBOAT2, miR-664b-3p, and Tousled-like kinase 1 (TLK1) mRNA in NSCLC tissues, along with their association with the clinical and pathological characteristics of NSCLC patients. Sequences or plasmids were transfected into A549 cells. …”
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