Tubeimoside I Inhibits the Proliferation of Liver Cancer Through Inactivating NF-κB Pathway by Regulating TNFAIP3 Expression by Zhang Y, Zhou M, Zhu L, Chen L, Zhang H, Huang Z, Zhou H

“…To uncover the molecular mechanisms, RNA sequencing was performed to identify the downstream targets of TBMS1. …”
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Bioprospecting of novel silica solubilizing bacteria as bioinoculants for sustainable silica management by Elina Maharjan, Sonam Mahawar, Surya Chauhan, Sudhir Kumar Upadhyay, Santosh Ranjan Mohanty, Ajaz Ahmad, Rajesh Kumar Singh, Devendra Jain

“…All potent silica-solubilizing plant growth-promoting rhizobacterial isolates were identified using 16S rDNA sequencing and belongs to Enterobacter sp., Serratia surfactantfaciens, and Klebsiella sp. …”
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Comparison of muscle magnetic resonance imaging data with clinical and laboratory parameters in follow-up of patients with idiopathic inflammatory myopathy by A. A. Kolomeyichuk, L. P. Ananyeva, A. N. Helkovskaya-Sergeeva, A. D. Koltakova, L. V. Ptichkina, D. O. Kazakov

“…All patients underwent MRI of the hip and calf muscles twice on the Philips Multiva 1.5 Tesla (Philips, The Netherlands) employing T1, T2, and STIR-T2 sequences, signs of oedema and fatty remodeling were assessed on a 4-point semiquantitative scale. …”
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Dysbiosis of Gut Microbiota Promotes Hepatocellular Carcinoma Progression by Regulating the Immune Response by Nan Zhang, Yusong Gou, Shan Liang, Ning Chen, Yali Liu, Qiushui He, Jing Zhang

“…This cross-sectional study is aimed at evaluating microbiome dysbiosis, gut damage, and microbial translocation in different stages of HCC. …”
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Production of Bacterial β-Galactosidase Using Wastes of Dairy Industry by Safaa Salah El-Din Taha, Osama Abd El-Hamid Ibrahim, Einas Hamed El-Shatoury, Amany Mohamed El-Deeb, Hayam Abd El-Naby Sayed

“…A total of eleven LAB isolates were evaluated for their ability to produce intracellular lactase in a submerged fermentation setup under static conditions. …”
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Measurable residual disease in hematologic malignancies: a biomarker in search of a standard by Namrata S. Chandhok, Mikkael A. Sekeres

“…Commonly used modalities for detecting MRD include multiparametric flow cytometry (MFC), next-generation sequencing (NGS), and polymerase chain reaction-based methods (PCR). …”
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Immune regulatory genes impact the hot/cold tumor microenvironment, affecting cancer treatment and patient outcomes by Mengmeng Sang, Jia Ge, Juan Ge, Juan Ge, Gu Tang, Qiwen Wang, Jiarun Wu, Liming Mao, Liming Mao, Xiaoling Ding, Xiaorong Zhou

“…Kyoto Encyclopedia of Genes and Genomes and Hallmark pathway enrichment were evaluated through gene set variation analysis. Additionally, hub genes that regulate the tumor microenvironment were identified, and their expression patterns were analyzed using single-cell RNA sequencing. …”
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Ultrasound assisted homing of human umbilical cord mesenchymal stem cells promotes recovery from acute respiratory distress syndrome by Bei-Ying Wang, Xiao Zhang, Ting-Tian Li, Wei-Wei Qin, Xiang Liu, Kong-Miao Lu, Li-Xin Sun, Wei Han

“…Cxcl5 and Igf1 was found to be differentially expressed and highly enriched by mRNA sequencing in MSC and sonicated groups and verified by PCR combined with ELISA. …”
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Predicting survival in bladder cancer with a novel apoptotic gene-related prognostic model by Ding-ming Song, Kun Feng, Wen-fei Luo, Dong-shan Lv, Li-po Zhou, Yi-bo He, Yanyang Jin

“…The model’s predictive ability for immunotherapy were evaluated using Tumor Immune Dysfunction and Exclusion (TIDE) and the Imvigor210 study.The single-cell sequencing was used to display the expression level of the ARGM.Finally,qRT-PCR was executed to validate the expression level of ARGM. …”
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The mitigative effects of Blautia producta 1009924 on DSS-induced intestinal inflammation by Yishu Chen, Yan Ma, Yang Leng, Xiaoling Li, Sishi Qin, Xiaoyan Li, Zhao Zhang, Zhao Zhang, Huajun Yu

“…In this study, a zebrafish intestinal inflammation model was established by induction with 0.5% dextran sulfate sodium (DSS) for 72 h to evaluate the effect of B. producta 1009924 on alleviating intestinal inflammation.ResultsThis strain B. producta 1009924 is a strict anaerobe, forming circular, off-white colonies on BHI medium. …”
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Adrenocortical carcinoma survival gene HMMR was identified as being targeted by fluorouracil and epirubicin using a gene coexpression network-based drug repositioning strategy by Zahra Jafari, Seyed-Morteza Javadirad, Seyede Elmira Yazdi Rouholamini

“…Hub gene expression was associated with TP53 mutations and cancer stage. Hub genes were evaluated using regression analysis. Hub genes were associated with immune cell infiltration. …”
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Cobalt Chloride-simulated Hypoxia Promoted Ossification of the Posterior Longitudinal Ligament Through the HIF1A–BMP4 Axis by Shihao Lu, Junbin Liu, Junzhe Sheng, Aochen Xu, Zichuan Wu, Chen Xu, Jiabin Yuan, Yang Liu

“…Osteogenic differentiation was evaluated through Alizarin Red S staining and alkaline phosphatase (ALP) assays, with optical density (OD) values measured using a microplate reader. …”
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Dietary Protein-Induced Changes in Archaeal Compositional Dynamics, Methanogenic Pathways, and Antimicrobial Resistance Profiles in Lactating Sheep by Maida Mushtaq, Xiaojun Ni, Muhammad Khan, Xiaoqi Zhao, Hongyuan Yang, Baiji Danzeng, Sikandar Ali, Muhammad Hammad Zafar, Guobo Quan

“…A total of nine fecal samples (three from each group) were analyzed via 16S rRNA and metagenomics sequencing. Higher archaeal alpha diversity and richness were observed in the H_m and H_h groups compared to the H_l group (<i>p</i> < 0.05). …”
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PALB2 deficiency may sensitize H3K27M-mutant pediatric HGG cells to BMN673/talazoparib by Xiaowen Guan, Xinke Xu, Xiaolan Mo, Houliang Deng

“…Additionally, we utilized whole-exome sequencing and CRISPR/Cas9 genome editing to generate Res259 cell lines with stable deficiencies in ARID1A, P53, or PALB2, followed by viability assays to evaluate drug sensitivity. …”
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KaiXinSan-JiaWei ameliorates cognitive dysfunction in APP/PS1 mice by intervening in gut microbiota and its metabolites by Lulu Mana, Fang Chen, Xiaoxia Yuan

“…Analysis of gut microbiota was conducted using 16S rRNA sequencing, and gut microbial metabolite (short chain fatty acids, SCFAs) content was detected using GC-MS. …”
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Non‐traditional yeasts from cool‐climate vineyards for novel low‐alcohol wines by Lihua Fan, Craig Doucette, Matthew B. McSweeney, Marcia English, Jun Song, Mindy Vinqvist‐Tymchuk, Gavin Kernaghan

“…The resulting wines were evaluated for sensory properties by 15 experienced panelists. …”
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Integrative analysis of epigenetic subtypes in acute myeloid Leukemia: A multi-center study combining machine learning for prognostic and therapeutic insights. by Jincan Li, Shengyue Wang

“…This study aimed to develop an integrated epigenetic-based classification system and evaluate its prognostic value.<h4>Methods</h4>We performed multi-omics analysis on five independent cohorts totaling 1,103 AML patients. …”
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Sparstolonin B potentiates the antitumor activity of nanovesicle-loaded drugs by suppressing the phagocytosis of macrophages in vivo by Yuefeng Zhang, Zuo Mou, Wei Song, Xiaoqin He, Qin Yi, Zhekai Wang, Xietong Mao, Wei Wang, Yangtao Xu, Yang Shen, Peng Ma, Kaihuan Yu

“…PANC-1 cell-derived tumors were established in nude mice in vivo, inhibitor pretreatment or no treatment was administered before intravenous injection of ENVs-DOX, and the therapeutic efficacy of ENVs-DOX was evaluated. Results NVs derived from PANC-1 cells were first prepared and identified. …”
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Reevaluation of the gastrointestinal methanogenic archaeome in multiple sclerosis and its association with treatment by Pei Yee Woh, Yehao Chen, Christina Kumpitsch, Rokhsareh Mohammadzadeh, Laura Schmidt, Christine Moissl-Eichinger

“…To address this, we re-evaluated the association between methanogenic archaea and MS using metagenomic data from the International Multiple Sclerosis Microbiome Study. …”
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Neurodevelopment Genes Encoding Olduvai Domains Link Myalgic Encephalomyelitis to Neuropsychiatric Disorders by Mauricio Arcos-Burgos, Mauricio Arcos-Holzinger, Claudio Mastronardi, Mario A. Isaza-Ruget, Jorge I. Vélez, Donald P. Lewis, Hardip Patel, Brett A. Lidbury

“…The sharing of these associations by the two cohorts supports their validity and grants the necessity of future studies to evaluate the implications for ME/CFS aetiology.…”
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