Identification of leaf rust resistance loci in hard winter wheat using genome‐wide association mapping by Indira Priyadarshini Lakkakula, James A. Kolmer, Rajat Sharma, Paul St. Amand, Amy Bernardo, Guihua Bai, Amir Ibrahim, Robert L. Bowden, Brett F. Carver, Jeffrey D. Boehm Jr., Meriem Aoun

“…A panel of 732 elite HWW genotypes was evaluated for response to US Pt races at the seedling stage and at the adult plant stage in leaf rust nurseries in Oklahoma, Texas, and Kansas. …”
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Alcohol-induced bone loss driven by dysregulated spatial distribution of gut microbiota and PGD2-IL17 pathway-mediated osteoclast activation by Haoyu Guo, Haoyu Guo, Yujing Bi, Gongzi Zhang, Shicheng Luo, Xiaopeng Jia, Xiaopeng Jia, Ruifu Yang, Ye Peng, Lihai Zhang

“…Segmented intestinal samples and fecal samples were analyzed using 16S rRNA sequencing and metabolomics. Mechanistic studies were conducted by supplementing R. intestinalis, prostaglandin D2 (PGD2), and its specific immune inhibitor, ramatroban. …”
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Characterization of Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> in Diarrhoeal Faeces from 0 to 5-Year-Old Children Attending Public Hospitals in Franceville,... by Anicet-Clotaire Dikoumba, Pierre Philippe Mbehang Nguema, Leresche Even Doneilly Oyaba Yinda, Romeo Wenceslas Lendamba, Jean Constan Obague Mbeang, Guy Roger Ndong Atome, Christophe Roland Zinga Koumba, Sylvain Godreuil, Richard Onanga

“…The objective was to evaluate the prevalence of antibiotic resistance to extended-spectrum beta-lactamase-producing <i>Escherichia coli</i> in children at public hospitals in Franceville, Gabon. …”
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Dried blood spot as alternative specimen for molecular epidemiology studies among HCV/HIV coinfected patients by Geane Flores, Barbara Vieira Lago, Amanda R Caetano, Jessica Silva, Vanessa Marques, Carlos Eduardo Brandão-Mello, Marcia Amendola-Pires, Jose Pilotto, Lia Lewis-Ximenez, Livia Melo Villar

“…HCV RNA from both serum and DBS samples was RT-PCR amplified and sequenced with HCV NS5B-specific oligonucleotides. …”
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Optimizing muscle mass and function in advanced lung cancer patients: randomized, double-blind, placebo-controlled trial protocol using High Eicosapentaenoic acid and PROtein (HEPR... by Imanuely Borchardt, Carla Prado, Tatiane Montella, Gisele Fraga Moreira, Gisele Farias, Marina Xavier Reis, Fernanda Taveira, Fernanda Carneiro Dias, Pedro De Marchi, Alberto Davalos, Carolina Alves Costa Silva, Carlos GilMoreira Ferreira, Andreia Melo, Wilza Peres

“…Conclusions The HEPRO study aims to evaluate a viable dietary intervention strategy to improve MM and function in patients with lung cancer.…”
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Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expr... by Milita Darguzyte, Philipp Antczak, Daniel Bachurski, Patrick Hoelker, Nima Abedpour, Rahil Gholamipoorfard, Hans A. Schlößer, Kerstin Wennhold, Martin Thelen, Maria A. Garcia-Marquez, Johannes Koenig, Andreas Schneider, Tobias Braun, Frank Klawonn, Michael Damrat, Masudur Rahman, Jan-Malte Kleid, Sebastian J. Theobald, Eugen Bauer, Constantin von Kaisenberg, Steven R. Talbot, Leonard D. Shultz, Brian Soper, Renata Stripecke

“…LV delivery harnessed the detection of lymphocyte subsets in bone marrow (αβ and γδ T-cells and NK cells) and the expression of HLA-DR. Furthermore, RNA sequencing showed that LV delivery increased the expression of different human reactome pathways, such as defense responses to other organisms and viruses. …”
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Pathologic Genetic Mutations May Correlate with Poor Visual Outcome in Patients with Hydroxychloroquine Retinopathy by Hsun-I. Chiu, Hui-Chen Cheng, Chih-Chiau Wu, Shih-Jen Chen, De-Kuang Hwang, Yi-Ming Huang, Yu-Bai Chou, Po-Kang Lin, Tai-Chi Lin, Ko-Hua Chen, Pei-Yu Lin, Yu-Fan Chang, An-Guor Wang

“…Abstract Introduction To evaluate the progression rate and identify potential genetic risk factors for poor visual outcome in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy. …”
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A Study of Spontaneous Self-Injurious Behavior and Neuroimaging in Rhesus Macaques by Ya-Li Zhang, Yi-Cheng Qiao, Yun-Chao Ji, Hong-Di Huang, Long Zhang, Jian-Xiong Ruan, Chen-Yao Li, Hui-Heng Xie, Bao-Lin Zhang, Qi Zhou, Sha-Sha Yue, Xiao-Mei Yu, Ming-Hao Qiu, Chuan-Kai Yu, Si-Chu Wu, Yu-Fang Zhou, Yan-Ling Li, Hong-Mei Zhu, Shu-Zhen Dong, Kang Huang, Yun Wang, Qiong Wang, Yi-Jiang Li, Ya Xie, Hui-Ling Chen, Long-Bao Lv, Shu Liu, Yong-Gang Yao, Chun Wang, Ning Liu, Jian-Hong Wang

“…However, previous studies have yet to comprehensively evaluate the translational value of self-injury in NHPs through integrated behavioral and neuroimaging characterization. …”
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Deciphering differential biomarkers for anti-interleukin-6 receptor and anti-tumour necrosis factor-α treatment response in rheumatoid arthritis by multiomics analysis by Emilie Gerard, Michel Didier, Matthias Herrmann, Inoncent Agueusop, Daniel Margerie, Anne Remaury, Raphaël Brard, Francesca Frau, Gilbert Thill, Yaligara Veeranagouda, Markus Kohlmann, Nadine Biesemann

“…Change in gene expression levels (n=522 peripheral blood samples from 261 patients) by both treatments was assessed using RNA sequencing analysis.Results Serum biomarkers most predictive to anti-IL-6R were different from those of anti-TNF-α; predictive biomarkers for anti-IL-6R were correlated with innate immune activation and synovial inflammation, while predictive biomarkers for anti-TNF-α seemed to be more T-cell and neutrophil-related. …”
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A TaqMan qPCR for precise detection and quantification of diarrheagenic Escherichia coli by Bingyu Xue, Huanrong Zhang, Xia Yan, Xiaoyan Su, Yuling Zhou, Junjin Xie, Sheng Li, Yang Zhou, Lin Li

“…To accurately and efficiently identify the five DEC types, this study retrieved the corresponding gene sequences from NCBI based on the virulence genes specified in Chinese national standards: invE, stx1, stx2, sth, stp, lt, aggR, astA, pic, bfpB, and escV. …”
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Predicting recurrence risk in endometrial cancer: a multisequence MRI intratumoral and peritumoral radiomics nomogram approach by Jie Li, Jie Li, Dianpei Ma, Dianpei Ma, Xiuting Chen, Xiuting Chen, Junting Wei, Junting Wei, Jiali Xu, Yingming Zhao, Zhizhen Gao

“…The predictive performance of the FM model was evaluated using receiver operating characteristic (ROC) curve analysis, calibration curve assessment, clinical decision curve analysis (DCA), clinical impact curve (CIC), and the DeLong test. …”
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Object Detection in Laparoscopic Surgery: A Comparative Study of Deep Learning Models on a Custom Endometriosis Dataset by Andrey Bondarenko, Vilen Jumutc, Antoine Netter, Fanny Duchateau, Henrique Mendonca Abrão, Saman Noorzadeh, Giuseppe Giacomello, Filippo Ferrari, Nicolas Bourdel, Ulrik Bak Kirk, Dmitrijs Bļizņuks

“…A custom dataset was curated, comprising of 199 video sequences and 205,725 frames. Of these, 17,560 frames were meticulously annotated by medical professionals. …”
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Large clones of clonal hematopoiesis affect outcome in mantle cell lymphoma: results from the FIL MCL0208 clinical trial by Simone Ragaini, Anna Galli, Elisa Genuardi, Martina Gandossini, Beatrice Alessandria, Aurora Maria Civita, Andrea Evangelista, Enrico Amaducci, Vittorio Stefoni, Federica Cavallo, Filippo Ballerini, Benedetta Puccini, Daniele Vallisa, Mariagrazia Michieli, Anna Pascarella, Angelo Palmas, Caterina Patti, Elisa Lucchini, Maria Grazia Careddu, Michele Merli, Massimiliano Postorino, Carola Boccomini, Monica Balzarotti, Vittorio Ruggero Zilioli, Maria Gomes da Silva, Benedetto Bruno, Ettore Rizzo, Marco Ladetto, Luca Malcovati, Simone Ferrero

“…Here, we report a comprehensive next-generation sequencing–based analysis of the M-CH mutational landscape at baseline and follow-up in patients enrolled in the Fondazione Italiana Linfomi MCL0208 phase 3 trial, evaluating lenalidomide maintenance vs observation after chemoimmunotherapy and autologous stem cell transplantation (ASCT) in untreated young patients with MCL. …”
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Differential diversity and structure of autotrophs in agricultural soils of Qinghai Province by Lianyu Zhou, Xuelan Ma, Qiaoyu Luo, Feng Qiao, Huichun Xie, Longrui Wang, Wenjuan Sun, Yu Liu, Yun Ma

“…This process was performed using Illumina amplicon sequencing of the ribulose-1,5-bisphosphatecarboxylase/oxygenase (RubisCO) gene (cbbL Form I) and activity data. …”
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Hemotropic pathogens in aborted fetuses of domestic ruminants: transplacental transmission and implications for reproductive loss by Daria Jurković Žilić, Šimun Naletilić, Željko Mihaljević, Ema Gagović, Silvio Špičić, Irena Reil, Sanja Duvnjak, Maja Zdelar Tuk, Adnan Hodžić, Relja Beck

“…PCR screening followed by sequencing were used to detect Anaplasmataceae, Babesia, Theileria, and hemotropic Mycoplasma.ResultsThirteen hemopathogens were detected in 94 of 651 fetuses (14.44%), including Anaplasma marginale, Anaplasma ovis, Anaplasma phagocytophilum, Theileria orientalis, Theileria ovis, Theileria sp. …”
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BCL6 promotes the progression of high-grade serous ovarian cancer cells by inhibiting PLAAT4 by An Wan, An Wan, An Wan, Wei-Dong Zhao, Gang Chen, Cheng Peng, Jin-Hui Tao, Jin-Hui Tao

“…Cleavage under targets and tagmentation (CUT&amp;Tag) was combined with RNA sequencing (RNA-seq) analyses to screen and identify the downstream regulatory mechanisms of BCL6. …”
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Architecture and implementation of ulrb algorithm in R by Francisco Pascoal, Rodrigo Costa, Luís Torgo, Catarina Magalhães, Paula Branco

“…Furthermore, we use a 16S rRNA gene amplicon sequencing dataset from the Arctic Ocean to provide illustrative examples, with code, on how to use and explore ulrb capabilities. …”
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Determination of biomarkers associated with neoadjuvant treatment response focusing on colibactin-producing Escherichia coli in patients with mid or low rectal cancer: a prospectiv... by Nicolas Barnich, Philippe Rouanet, Marta Jarlier, Caroline Chevarin, Johan Gagniere, Mathilde Bonnet, Pierre-Emmanuel Colombo, Guillaume Carrier, Hélène de Forges, Christophe Taoum, Gwenaelle Roche, Catherine Fiess

“…Currently, no study has evaluated the potential association between intestinal microbiota composition and tumour response to CRT in mid and low rectal cancer. …”
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<i>Rotavirus alphagastroenteritidis</i>: Circulating Strains After the Introduction of the Rotavirus Vaccine (Rotarix^®) in Luanda Province of Angola by Dikudila G. Vita, Cristina Santiso-Bellón, Manuel Lemos, Zoraima Neto, Elsa Fortes-Gabriel, Miguel Brito, Cruz S. Sebastião, Jesus Rodriguez-Diaz, Celso Cunha, Claudia Istrate

“…The aim of this study was to evaluate the distribution of <i>R. alphagastroenteritidis</i> genotypes among children under five years of age, hospitalized with acute gastroenteritis (AGE), after the introduction of the rotavirus vaccine. …”
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From clinical observations to molecular insights: Decoding immune checkpoint inhibitors‐induced prostatitis by Peng Luo, Ying Liu, Lan Xu, Zaoqu Liu, Linhui Wang, Hank Z. H. Wong, Quan Cheng, Anqi Lin, Xiao Fang, Aimin Jiang

“…Food and Drug Administration Adverse Event Reporting System (FAERS) database and evaluated risk through the application of the reporting odds ratio. …”
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