Identifying rhizosphere bacteria and potential mechanisms linked to compost suppressiveness towards Fusarium oxysporum by Hildah Amutuhaire, Adi Faigenboim-Doron, Judith Kraut-Cohen, Jonathan Friedman, Eddie Cytryn

“…Several studies have underlined the role of microorganisms in disease suppression, but the mechanisms facilitating this disease suppression remain unclear. We evaluated the impact of compost amendment on the composition and functional capacity of the rhizosphere microbiome in cucumber plants (Cucumis sativus) inoculated with Fusarium oxysporum f. sp. radicis-cucumerinum (FORC) under controlled greenhouse conditions using amplicon sequencing, shotgun metagenomic and culture-based techniques. …”
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A Photosynthetic Bacterium Suitable for Treating High-Salinity Sea Cucumber Boiling Broth by Shaokun Dong, Yusi Guo, Jinrui Ji, Pu Song, Ning Ma, Hongjin Qiao, Jinling Cai

“…This study aimed to evaluate a photosynthetic bacterium capable of effectively treating SCBB, which was isolated from the intertidal sediment samples. …”
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Mechanical characterization of epoxy-HA hybrid composites reinforced with woven carbon fiber and nylon fiber mesh for external fixator by Harini Sosiati, Ankas Pamasti, Rahmad Kuncoro Adi, Aulia Zaki Kusuma, Putra Dwi Darmawan, Totok Suwanda

“…Four different layering sequences (C-N-C-N-C, C-N-N-C-C, N-C-N-C-C, and N-N-C-C-C) were tested to evaluate their mechanical performance for potential application in external fixators. …”
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Pyroptosis drives tumor progression and immune evasion in Hepatocellular Carcinoma: a single-cell and spatial transcriptomic study by Siyu Tao, Yunhao Yang

“…Methods Single-cell RNA sequencing (scRNA-seq) data from 10 HCC patients were obtained from the GEO database (GSE149614), along with spatial transcriptomic data and bulk RNA-seq data from TCGA. …”
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Single-cell transcriptomic analysis of the human vascular atlas provides new insights into vasorelaxation redundancy and heterogeneity by Elisa Avolio, Sarah F. Pearce, David Wambeke, Paolo Madeddu

“…However, it remains unknown whether vasorelaxant mediators reiterate this pattern.Working hypothesisThe expression of “sentinel” gene transcripts provides a first insight into angiotypic and organotypic heterogeneity of vasorelaxation.MethodsThe expression of NO- and PGI2-generating enzymes and potassium channels was evaluated by analyzing single-cell RNA-sequencing data derived from the Human Vascular Cell Atlas. …”
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Gut Microbiome dysbiosis and immune activation correlate with somatic and neuropsychiatric symptoms in COVID-19 patients by Paula L. Scalzo, Austin G. Marshall, Sirena Soriano, Kristen Curry, Mario Dulay, Timea Hodics, Eamonn M. M. Quigley, Todd J. Treangen, María M. Piskorz, Sonia Villapol

“…Gut microbiome profiling was performed using full-length 16 S rRNA gene sequencing to evaluate microbial diversity and composition. …”
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Linking changes in the soil microbial community to C and N dynamics during crop residue decomposition by Cyrine REZGUI, Isabelle TRINSOUTROT-GATTIN, Marie BENOIT, Karine LAVAL, Wassila RIAH-ANGLET

“…It is an important management strategy that can improve soil fertility and enhance agricultural productivity. This work aims to evaluate the extent of the changes that may occur in the soil heterotrophic microbial communities involved in organic matter decomposition and C and nitrogen (N) mineralization after the addition of crop residues. …”
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Exploiting mitochondrial dysfunction to overcome BRAF inhibitor resistance in advanced melanoma: the role of disulfiram as a copper ionophore by Bolun Zhao, Fazhan Ban, Yuehua Li, Qiong Shi, Sen Guo, Xiuli Yi, Huina Wang, Tianwen Gao, Chunying Li, Guannan Zhu

“…RNA sequencing identified downstream factors regulated by intracellular copper levels, and the CRISPR-Cas9 system was used to knock out candidate genes in BRAFi-resistant cells for mechanistic validation. …”
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Activity of β-Lactamase Inhibitor Combinations Against Enterobacterales Isolated from Patients with Intra-Abdominal Infection from United States Medical Centres (2019–2023) by Helio S. Sader, John H. Kimbrough, Marisa L. Winkler, Rodrigo E. Mendes, Mariana Castanheira

“…<b>Objective</b>: To evaluate the antimicrobial susceptibility of Enterobacterales isolated from patients with intra-abdominal infections (IAI) in United States (US) medical centres. …”
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Intestinal flora and metabolomics of post-discharge elderly CAP patients treated with syndrome differentiation in traditional Chinese medicine by LIU Xiaopeng, ZHOU Linqiong, MENG Yuanyuan, YAN Zihan, WANG Minghang

“…Objective To evaluate the effect of syndrome differentiation in traditional Chinese medicine on intestinal flora and metabolomics in elderly patients with community-acquired pneumonia（CAP）after discharge from the hospital. …”
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Paternal advanced age and sperm quality are indicators for Preimplantation Genetic Testing in egg donation cycles by Jeimy Pedraza, Hugo Sierra, Jacqueline Cordero, Esther López-Bayghen

“…Semen characteristics were evaluated by a seminogram. Biopsies were performed on Day 5 or Day 6, and Preimplantation Genetic Testing for Aneuploidies (PGT-A) was used to determine chromosome integrity with Next-Generation Sequencing. …”
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GRLGRN: graph representation-based learning to infer gene regulatory networks from single-cell RNA-seq data by Kai Wang, Yulong Li, Fei Liu, Xiaoli Luan, Xinglong Wang, Jingwen Zhou

“…The reconstruction of GRNs can help investigate cellular dynamics, drug design, and metabolic systems, and the rapid development of single-cell RNA sequencing (scRNA-seq) technology provides important opportunities while posing significant challenges for reconstructing GRNs. …”
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598 Neutrophils propagate inflammation and fibrosis in primary sclerosing cholangitis by Abid Anwar, Sofia Jerez Ortega, Maleeha Kalaiger, Kaitlin Friesland, Jordan Young, Amaury E. Tuerlinckx, Usman Yaqoob, Robert C. Huebert, Nidhi Jalan-Sakrikar

“…Intrahepatic leukocytes (IHL) isolated from mice livers were evaluated for neutrophil abundance and activation state. …”
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CIP2A promotes inflammation and exacerbates osteoarthritis by targeting CEMIP by Jingyue Su, Xuying Sun, Xin Chen, Kang Wei, Danni Luo, Shengwu Yang, Chunwu Zhang, Jian Xu, Zhenhan Deng

“…Downstream of CIP2A was screened by RNA sequencing and coimmunoprecipitation coupled with mass spectrometry in mouse chondrocytes. …”
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Enhanced intraoperative visualization of the optic chiasm using contrast-enhanced balanced steady-state free precession imaging during endoscopic transsphenoidal surgery by Yosuke Fujimoto, Masaaki Kohta, Yuichi Fujita, Masaaki Taniguchi, Tomoaki Nakai, Kazuhiro Tanaka, Atsushi Fujita, Eiji Kohmura, Takashi Sasayama

“…Abstract Preoperative balanced steady-state free precession (bSSFP) imaging is helpful in endoscopic transsphenoidal surgery (ETSS) for accurately evaluating the optic chiasm and surrounding structures. …”
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Plinabulin exerts an anti-proliferative effect via the PI3K/AKT/mTOR signaling pathways in glioblastoma by Rouxin Wang, Jing Cheng, Huanqi Zhang, Kaizhi Luo, Rui Wu, Yangling Li, Yuanheng Zhu, Chong Zhang

“…Crucial target genes were identified through RNA sequencing and bioinformatics analysis. Protein levels were evaluated in a concentration-dependent manner using western blot analysis.Results: Plinabulin suppressed glioblastoma cell proliferation by causing cell cycle G2/M phase arrest and inhibited migration. …”
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Spatial distribution and source apportionment of nitrogen in typical plain river networks and bacterial community response by Aiju You, Aiju You, Qiaoxi Zheng, Pengcheng Yao, Pengcheng Yao

“…And the changes of the bacterial community were analyzed through 16S rRNA gene sequencing.ResultsThe concentration of total nitrogen (TN) revealed a distinct spatial pattern, with the industrial area demonstrating the highest levels, followed closely by the aquaculture area and the domestic and agricultural areas. …”
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In Vitro Activities of Ceftazidime-Avibactam and Comparator Agents Against Carbapenem-resistant Enterobacterales (CRE) Collected in Africa/Middle East ATLAS Global Surveillance Pro... by Dr Meredith Hackel, Dr Gregory Stone, Dr Daniel Sahm

“…Isolates nonsusceptible to meropenem were screened for metallo-β-lactamase (MBL) genes by PCR and sequencing. Results: Ceftazidime-avibactam was active against more Enterobacterales isolates than all comparators tested (95.1% susceptible; MIC₉₀ = 1 mg/L). …”
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LINC02167 stabilizes KSR1 mRNA in an m5C-dependent manner to regulate the ERK/MAPK signaling pathway and promotes colorectal cancer metastasis by Junwen Qi, Tao Jiang, Bowen Liu, Qihang Hu, Junnan Chen, Ning Ma, Yixin Xu, Hu Song, Jun Song

“…Methods LINC02167 expression was analyzed in CRC tissues via real-time quantitative polymerase chain reaction and fluorescence in situ hybridization. Functional assays evaluated its role in CRC cell migration, invasion, and metastasis in vitro and in vivo. …”
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Effects of arabinoxylan on BDNF/TrkB/p-CREB signaling pathway in the prefrontal cortex and intestinal microbiome in post-stroke depressed rats by Bin-yu Bi, Lin Lin, Liu Huang, Jun Zhou, Wei-juan Yan, Ling Huang, Jie Wang, Xue-bin Li

“…Body mass, sugar and water consumption experiments and open-field experiments were used to evaluate the behavior of rats. The pathological changes were observed by H&E staining. …”
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