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7661
Irisin mitigates osteoporotic-associated bone loss and gut dysbiosis in ovariectomized mice by modulating microbiota, metabolites, and intestinal barrier integrity
Published 2025-04-01“…Gut microbiota composition was examined via 16S rDNA sequencing. Intestinal cytokines and barrier proteins were measured using immunohistochemistry and ELISA. …”
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7662
Epithelial Membrane Protein 1 is a Potential Prognostic Biomarker for Ovarian Cancer
Published 2022-11-01“…Oncomine and Gene Expression Profiling Interactive Analysis tools (GEPIA) were used to evaluate EMP1 expression. EMP1 alterations were identified using cBioPortal and the prognostic value of EMP1 was assessed using Kaplan-Meier analysis and OncoLnc online tools. …”
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7663
Extended-Spectrum Beta-Lactamase- and Plasmidic AmpC-Producing <i>Enterobacterales</i> among the Faecal Samples in the Bulgarian Community
Published 2024-08-01“…Antimicrobial susceptibility was evaluated by the disk diffusion method. <i>bla</i><sub>ESBL</sub> or plasmidic AmpC (pAmpC) genes were detected by PCR and sequencing. …”
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7664
EEG spectral cohrence inter and intrahemispheric during catching object fall task Coerência espectral do eletrencefalograma inter e intra-hemisférica durante a tarefa de apreensão...
Published 2007-03-01“…The aim of the present study was to evaluate coherence measures at Theta through qEEG during the accomplishment of a specific motor task. …”
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7665
The use of propensity score matching to assess the effectiveness of the endometrial receptivity analysis in patients with recurrent implantation failure
Published 2025-01-01“…BackgroundOne potential cause of implantation failure is abnormal endometrial receptivity, and how to objectively evaluate endometrial receptivity has been a matter of great concern. …”
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7666
Unveiling the cytotoxicity of Red Sea Moorena producens via LC-QTOF-MS/MS chemical profiling, network pharmacology, and molecular docking
Published 2025-12-01“…Marine cyanobacteria, such as Moorena producens belonging to the family: Oscillatoriaceae, are rich sources of bioactive compounds with potential anticancer properties.Objective This study aims to identify and characterize bioactive compounds from M. producens and evaluate their anticancer activity against breast and liver cancer cell lines.Materials and methods M. producens was collected and authenticated using 16S rRNA sequencing. …”
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7667
Hepatobiliary phase manifestations of breast cancer liver metastasis: differentiating molecular types through Gd-EOB-DTPA-enhanced MRI
Published 2025-03-01“…Abstract Objective The primary objective of this study is to evaluate the diagnostic efficacy of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) -enhanced magnetic resonance imaging (MRI) in distinguishing breast cancer liver metastasis (BCLM) across different molecular types. …”
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7668
Oxidative stress gene expression in ulcerative colitis: implications for colon cancer biomarker discovery
Published 2025-07-01“…This study aimed to identify key molecules and pathways involved in the co-occurrence of CRC and UC, as well as the role of oxidative stress in disease progression, through bioinformatics analysis of public RNA sequencing databases. We downloaded datasets from public repositories and conducted gene set enrichment analysis (GSEA), screening for oxidative stress-related differentially expressed genes (OXSRDEGs) to evaluate their diagnostic potential. …”
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7669
Effects of immersive leisure-based virtual reality cognitive training on cognitive and physical function in community-based older adults: A randomized controlled trial
Published 2025-04-01“…The control group received non-cognitive training. The outcomes evaluated were cognitive function assessed by Montreal Cognitive Assessment (MoCA), immediate memory assessed by Wechsler Memory Scale (WMS)-Word List, working memory and mental flexibility assessed by WMS-Digit Span Forward, WMS-Digit Span Backward, and WMG-Digit Span Sequencing (DSS), and physical function assessed by the Timed Up and Go (TUG) test. …”
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7670
Molecular and genetic diversity in melanoma of eye
Published 2018-11-01“…The following genes were studied by Sanger sequencing: GNAQ, GNA11, KIT, BRAF, NRAS. Results. Mutations in GNAQ and GNA11 were found in 81 % (59/73) of UM, in 42 % (31/73) and 38 % (28/73) of cases correspondently. …”
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7671
Comprehensive Analysis of Multi-Omics Data on RNA Polymerase as an Adverse Factor in Head and Neck Squamous Cell Carcinoma
Published 2025-03-01“…Focusing on head and neck squamous cell carcinoma (HNSC), we integrated bulk RNA sequencing, single-cell, and spatial transcriptome data to identify POLR2C expression patterns and its potential regulation by Yin Yang 1 (YY1). …”
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7672
Maternal Transmission of Rotavirus to Calves and Comparison of Colostrum and Fecal Microbiota in Holstein and Hanwoo Cattle
Published 2024-11-01“…This study aimed to evaluate rotavirus transmission to calves and analyze microbial communities in cow milk and neonatal calf feces within dairy and beef cattle. …”
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7673
The bile duct and liver cancer: ON-treatment surveillance of tumor evolution and response to systemic treatment (BILLIONSTARS) study
Published 2025-06-01“…Tissue obtained in the clinical setting through surgery or biopsy along with tissue from research autopsies will be evaluated with targeted deep sequencing. Circulating tumor DNA (ctDNA) and other relevant biomarkers will be analyzed in blood samples obtained at different timepoints, depending on the type of treatment; before surgery or the start of systemic treatment, prior to each course of systemic treatment, if applicable, and at end of treatment. …”
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7674
Improving prenatal diagnosis with combined karyotyping, CNV-seq and QF-PCR: a comprehensive analysis of chromosomal abnormalities in high-risk pregnancies
Published 2025-01-01“…We evaluated clinical characteristics, diagnostic yields, and inter-method concordance rates. …”
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7675
Therapeutic potential of a newly isolated bacteriophage against multi-drug resistant Enterococcus faecalis infections: in vitro and in vivo characterization
Published 2025-02-01“…The phage genome was purified, sequenced, and subjected to bioinformatics analysis for identifying and characterizing its features, as well as, the suitability for clinical application. …”
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7676
Clinical, Radiological, and Molecular Findings in Cases with TRAPPopathies
Published 2023-09-01“…Clinical, radiological, and molecular findings obtained by whole exome sequences of cases were re-evaluated. Results: Molecular analysis revealed homozygous c.454+3A>G p.(?) …”
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7677
Clinical characteristics, diagnosis, outcomes and lung microbiome analysis of invasive pulmonary aspergillosis in the community-acquired pneumonia patients
Published 2023-07-01“…The lung microbiome detected by mNGS was characterised and its association with clinical features was evaluated.Main results IPA was diagnosed in 26 (23.4%) of 111 CAP patients. …”
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7678
Biomimetic phosphorus dendrimer multi-epitope nanovaccine enhances humoral and cellular immune response against African swine fever virus
Published 2025-07-01“…Single-cell RNA sequencing (scRNA-seq) revealed that immunization with PPH-Nb-rAg@PM increased the proportions of B cells, T cells, NK cells, plasma cells, and macrophages in the mouse spleen. …”
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7679
Association of rs440446 in the APOE intron region with multidimensional cognitive function, lipid/metabolic markers, and spontaneous neural activity in Chinese urban community-dwel...
Published 2025-07-01“…Fractional amplitude of low-frequency fluctuations (fALFF) was used to evaluate differences in spontaneous neural activity, and Pearson correlations were calculated between fALFF values and cognitive function.Resultsrs440446 GG homozygotes were associated with poorer language function. …”
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7680
Characterization of alginate-degrading bacteria isolated from seaweed-producing areas of South Korean territory and verification of the bacteria as plant growth-promoting biofertil...
Published 2025-06-01“…This study isolated 13 alginate-degrading bacterial strains from over a thousand seaside soil bacteria in South Korea and investigated their alginate-degrading characteristics. Through 16S rDNA sequencing, Marinomonas sp., Zobellella sp., and Pseudomonas sp. were newly identified at the subspecies level. …”
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