Fecal microbiota landscape of commercial poultry farms in Faisalabad, Pakistan: A 16S rRNA gene-based metagenomics study by Muhammad Moman Khan, Muhammad Ahmed Mushtaq, Muhammad Suleman, Umer Ahmed, Muhammad Faisal Ashraf, Rizwan Aslam, Mashkoor Mohsin, Stefan Rödiger, Yasra Sarwar, Peter Schierack, Aamir Ali

“…Fecal samples from 18 poultry farms (twelve layers and six broilers) in Faisalabad, Pakistan were analyzed using 16S rRNA gene sequencing of the V3-V4 region to evaluate bacterial composition. …”
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UBE2N modulates osteoclast differentiation via BTK-PLCγ2-Ca2+ signaling pathway to promote osteoporosis by Yiqing Chen, Ruixue Ying, Liya Ai, Fang Dai, Qiu Zhang, Ping Wang, Fuhua Chen

“…The aim of this study is to evaluate the effects and mechanisms of UBE2N in promoting osteoclastogenesis. …”
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Integrated analyses and a novel nomogram for the prediction of significant fibrosis in patients by Mengxin Lu, Shuai Tao, Xinyan Li, Qunling Yang, Cong Du, Weijia Lin, Shuangshuang Sun, Conglin Zhao, Neng Wang, Qiankun Hu, Yuxian Huang, Qiang Li, Yi Zhang, Liang Chen

“…A nomogram that included the three factors was tabled to evaluate the probability of significant fibrosis occurrence. …”
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Polymorphisms in the <i>SNCA</i> gene and the risk of synucleopathy by Natalia Yu. Abramycheva, Ludmila S. Karan, Anna O. Protopopova, Ivan V. Minaev, Irina A. Berdalina, Ekaterina Yu. Fedotova, Sergey N. Illarioshkin

“…Genotyping of 16 SNPs of the SNCA gene was performed by direct Sanger sequencing on a capillary genetic analyzer. The Benjamini–Hochberg procedure was applied for multiple pairwise comparisons. …”
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Unmet needs in abnormal uterine bleeding due to ovulatory dysfunction by Tommaso Simoncini, Hisham Arab, Nataliia Pedachenko, Qinjie Tian, Fernando Pineda, Balamba Puranam, Rubina Sohail, Maria Celeste Osorio Wender

“…There remains regional disparity in treatment practices, often influenced by institutional and insurance regulations as well as cultural and religious practices. A panel of experts evaluated current gaps in ovulatory disorder management guidelines and discussed potential strategies for addressing these unmet needs. …”
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Repositioning of moxidectin: a promising approach in cutaneous leishmaniasis therapy by Al Samra Lynn, El Nahas Mohamad, Mneimneh Ilham, Tokajian Sima, Nemer Georges, Sinno Aia, Rahy Kelven, Thoumi Sergio, Zibara Zahraa, El Khatib Ahmad, Sabbagh Dalal, Guillot Jacques, Karam Louna, Ali Lazo, Baghdadi Ruqaya, Al Khoury Charbel

“…Additionally, we evaluated the therapeutic index of MOX using the Galleria mellonella infection model. …”
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Isolation and Characterization of Colistin-Resistant <i>Enterobacteriaceae</i> from Foods in Two Italian Regions in the South of Italy by Rosa Fraccalvieri, Angelica Bianco, Laura Maria Difato, Loredana Capozzi, Laura Del Sambro, Stefano Castellana, Adelia Donatiello, Luigina Serrecchia, Lorenzo Pace, Donatella Farina, Domenico Galante, Marta Caruso, Maria Tempesta, Antonio Parisi

“…This study aimed to assess the prevalence of colistin-resistant <i>Enterobacteriaceae</i> in raw and ready-to-eat food samples collected from two regions of Italy (Apulia and Basilicata) and to evaluate their resistance phenotypes and genetic characteristics. …”
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Production of Indole-3-Acetic Acid and Degradation of 2,4-D by Yeasts Isolated from Pollinating Insects by Camila G. de Oliveira, Angela Alves dos Santos, Eduardo J. P. Pritsch, Stéfany K. Bressan, Anderson Giehl, Odinei Fogolari, Altemir J. Mossi, Helen Treichel, Sérgio L. Alves

“…Seven yeast strains were isolated from insects, identified via ITS sequencing, and assessed for IAA production in YPD medium. …”
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Unveiling the potential of native Blueberry-derived yeasts as biocontrol agents against Botrytis cinerea and Alternaria alternata by Florencia Isabel Chacón, Pedro Eugenio Sineli, Santiago Bernabé Guiñazú, Fátima Micaela Alvarez, Anja Poehlein, Rolf Daniel, Julián Rafael Dib

“…Native yeasts were isolated and identified based on the PCR-amplified and sequenced D1/D2 domains of the 26S rRNA gene. Members of the genera: Rhodotorula, Hanseniaspora, Naganishia, Moesziomyces, Rhizosphaera, Metschnikowia, Clavispora, Pallidophorina, Hannaella, Aureobasidium, Sporobolomyces, Filobasidium, and Cystobasidium were identified. …”
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Chlorophyll a/b-binding Overexpression 2 regulates nitric oxide signaling in Arabidopsis response to sulfur deficiency by Oluwaseun Olayemi Aluko, Zhixin Liu, Yaping Zhou, Hao Liu, Aizhi Qin, Qianli Zhao, Mengfan Li, Chunyang Li, Luyao Kong, Lulu Yan, Vincent Ninkuu, Jean-David Rochaix, Lam-Son Phan Tran, Xuwu Sun

“…WT roots had more upregulated genes than the coe2 roots; thus, activation of these genes is tightly linked to WT and coe2 root responses to LS stress. We further evaluated the involvement of AtPSBO1 (a photosynthetic-inducible gene) in coe2 growth regulation under LS conditions. …”
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The rise of serotype 8 is associated with lineages and mutations in the capsular operon with different potential to produce invasive pneumococcal disease by Covadonga Pérez-García, Aída González-Díaz, Mirian Domenech, Mirella Llamosí, Aída Úbeda, Juan Carlos Sanz, Ernesto García, Carmen Ardanuy, Julio Sempere, Jose Yuste

“…In this study, we elucidate the rise of serotype 8 causing IPD in Spain. We evaluated isolates received during the period 2008–2023 including whole genome sequencing characterization and host–pathogen interaction studies. …”
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Identification and Phylogenetic Analysis of <i>Flavobacterium</i> spp. Associated with Aquaculture Fish Diseased from Brazil by Peter Charrie Janampa-Sarmiento, Henrique Lopes Costa, Júlio César Câmara Rosa, Guilherme Campos Tavares, Henrique César Pereira Figueiredo

“…Due to the recent taxonomic reclassification of the species <i>Flavobacterium columnare</i> into four new species—<i>Flavobacterium columnare</i>, <i>Flavobacterium davisii</i>, <i>Flavobacterium covae</i>, and <i>Flavobacterium oreochromis</i>—it is necessary to re-evaluate isolates of previous outbreaks to better understand the epidemiology related to this bacterial group. …”
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Calcium-Sensing Receptor as a Novel Target for the Treatment of Idiopathic Pulmonary Fibrosis by Kasope Wolffs, Renjiao Li, Bethan Mansfield, Daniel A. Pass, Richard T. Bruce, Ping Huang, Rachel Paes de Araújo, Bahareh Sadat Haddadi, Luis A. J. Mur, Jordanna Dally, Ryan Moseley, Rupert Ecker, Harry Karmouty-Quintana, Keir E. Lewis, A. John Simpson, Jeremy P. T. Ward, Christopher J. Corrigan, Renata Z. Jurkowska, Benjamin D. Hope-Gill, Daniela Riccardi, Polina L. Yarova

“…To address this question, we evaluated polyamine abundance using metabolomic analysis of IPF patient saliva. …”
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Stemness-driven clusters in ovarian cancer: immune characteristics and prognostic implications by Xinyan Zeng, Xinyan Zeng, Wentian Wu, Xiaoqin Li, Xiaoqin Li, Xiaorui Wu, Xiaorui Wu, Yingying Du, Ping Li, Ping Li, Ping Li

“…Differences in the tumor microenvironment (TME), tumor mutation burden (TMB), immune checkpoint expression, and drug sensitivities were evaluated between risk groups. Single-cell RNA sequencing was used to investigate stemness-related cell types. …”
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Comprehensive characterization of NK cell-related genes in cutaneous melanoma identified a novel prognostic signature for predicting the prognosis, immunotherapy, and chemotherapy... by Haili Ma, Jian Liu, Huan Jin, Min Zhang, Qian Liang, Zhiqiang Guo

“…The model's accuracy and efficacy were evaluated through various statistical methods. Immunological characteristics, as well as the effectiveness of immunotherapy and chemotherapy in groups defined by the NKIGs signature, were explored. …”
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Prenatal Diagnosis of Fetal Visceral Situs Abnormalities: A Retrospective Study by Xiaoping Gong, Mingli Lv, Guanjie Wang, Yunyun Cao, Ping Chen, Hui Wang

“…Background: To explore the necessity for prenatal diagnosis and evaluate related diagnostic methods for fetal visceral situs abnormalities. …”
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A Comprehensive Review of Detection Methods for <i>Staphylococcus aureus</i> and Its Enterotoxins in Food: From Traditional to Emerging Technologies by Assia Mairi, Nasir Adam Ibrahim, Takfarinas Idres, Abdelaziz Touati

“…This review critically evaluates modern and traditional methodologies for detecting <i>S. aureus</i> and its enterotoxins in food matrices, emphasizing their principles, applications, and limitations. …”
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New insights into the cultivability of human milk bacteria from ingestion to digestion and implications for their Immunomodulatory properties by Charles Le Bras, Alizé Mouchard, Lucie Rault, Marie-Françoise Cochet, Olivia Ménard, Nolwenn Jacquet, Victoria Chuat, Florence Valence, Yves Le Loir, Amandine Bellanger, Amélie Deglaire, Isabelle Le Huërou-Luron, Sergine Even

“…This approach enabled a more in-depth investigation of CM than conventional methods based on the individual sequencing of a subset of isolates and resulted in a moderate gain in diversity within each HM sample. …”
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A rare homozygous INS variant causes adult-onset diabetes by Cees J Tack, Tine Glendorf, Hanka Venselaar, Ron A Wevers, Jolein Gloerich, Roel Tans, Antonius E van Herwaarden, Danique M H van Rijswijck, Alain van Gool

“…Insulin receptor affinity and downstream signaling potency were evaluated in vitro.Results Auto-immune diabetes was excluded. …”
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Functional analysis of Parabacteroides distasonis F4: a novel probiotic strain linked to calf growth and rumen fermentation by Xiaoran Feng, Yunlong Liu, Shengyang Xu, Junnan Ma, Hao Yuan, Haixin Wang, Jiachen Hu, Sijie Jin, Shanji Liu, Jin Zhong, Tao Ma, Yan Tu

“…This study aims to identify a target strain based on the findings from multi-omics analysis and literature review, isolating and evaluating the target microbial strains from both the rumen and hindgut contents for their probiotic potential. …”
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